Veterinary dermatology最新文献_第9页

In vitro efficacy of a topical antimicrobial mousse and shampoo at proximal and distal hair locations against Staphylococcus pseudintermedius and Staphylococcus schleiferi. 局部抗菌慕斯和洗发水在头发近端和远端对pseudintermedius葡萄球菌和schleiferi葡萄球菌的体外疗效。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-09-25 DOI: 10.1111/vde.13206

Tia T Taketa, Wayne S Rosenkrantz, Craig E Griffin, Willie A Bidot

{"title":"In vitro efficacy of a topical antimicrobial mousse and shampoo at proximal and distal hair locations against Staphylococcus pseudintermedius and Staphylococcus schleiferi.","authors":"Tia T Taketa, Wayne S Rosenkrantz, Craig E Griffin, Willie A Bidot","doi":"10.1111/vde.13206","DOIUrl":"10.1111/vde.13206","url":null,"abstract":"Background: Topical therapy is essential in assisting with the resolution of pyoderma.Objectives: (i) Evaluate the in vitro efficacy and residual activity of two different hair segments treated with shampoo and mousse against meticillin-sensitive and meticillin-resistant staphylococci; (ii) compare proximal and distal hair portions treated with the products and (iii) describe a new disc diffusion method for assessing residual efficacy.Animals: Eleven privately owned, medium-haired dogs.Materials and methods: In this randomised, blinded and negatively controlled study, dogs were treated once with a 3% chlorhexidine digluconate-0.5% ophytrium shampoo on the lateral thorax, and the corresponding mousse on the opposite side. Hairs were plucked before treatment, two hours post-treatment, and day (D)2, D4, D7, D10 and D14. Hairs were weighed (0.01 g) and cut (1.0 cm) from the proximal portion, moistened with saline and placed on a sterile diffusion disc to absorb the solution. Proximal and distal hair bundles and diffusion discs were placed onto agar inoculated with an isolate of meticillin-sensitive or meticillin-resistant Staphylococcus pseudintermedius or Staphylococcus schleiferi. Inhibition zones were measured following incubation.Results: Distal hairs had larger (p < 0.001) inhibition zones compared to proximal hairs. Mousse had significant differences (p < 0.05) between time points and locations for both the hair bundles and discs, while shampoo only had a significant difference (p < 0.001) between time points for the hairs.Conclusions and clinical relevance: Mousse was effective, and shampoo was only minimally effective in inhibiting bacterial growth in vitro, with the greatest effect occurring at the two hours time point. The distal hair shafts had greater inhibition.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"156-165"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41149336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal pilot study examining the effect of punch biopsy on equine sarcoid growth dynamics. 纵向试验研究，探讨打孔活检对马肉瘤生长动态的影响。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-02 DOI: 10.1111/vde.13236

Lien Gysens, Ann Martens, Maarten Haspeslagh

{"title":"Longitudinal pilot study examining the effect of punch biopsy on equine sarcoid growth dynamics.","authors":"Lien Gysens, Ann Martens, Maarten Haspeslagh","doi":"10.1111/vde.13236","DOIUrl":"10.1111/vde.13236","url":null,"abstract":"Background: Nonexcisional tissue biopsies facilitate pre-operative confirmation of equine sarcoid yet fear of lesion deterioration currently limits its use in the diagnostic workup.Objectives: To evaluate the effect of a single punch biopsy on tumour growth dynamics [thickness, area, circumference, viral load (VL) and Visual Analog Scale (VAS)].Animals: Six client-owned horses with 11 sarcoids of various classification.Materials and methods: Growth dynamics were recorded on a weekly basis, 12 weeks pre- and 24 weeks post-biopsy. The effect of a single punch biopsy on growth dynamics was estimated by linear mixed-effect models. Spearman's rank correlation coefficient (SRCC) was calculated to investigate correlations with the number of weeks before and after the intervention.Results: While statistically significant post-biopsy changes were recorded for all parameters except VL, no parameter was consistently increased after the biopsy intervention. In two of 11 sarcoids, the VL correlation pattern revealed significant strong correlations: sarcoid 6 (pre: r = -0.66, p < 0.05; post: r = 0.81, p < 0.001), increased VL; and sarcoid 8 (pre: r = 0.85, p < 0.001; post: r = 0.17, p > 0.05), no further increase after biopsy.Conclusions and clinical importance: Our results indicate that post-biopsy lesion deterioration is not a general concept that applies to all sarcoids, and both deterioration or improvement are possible outcomes over a 24-week period. Further clinical studies with a larger sample size are needed before a definitive conclusion can be made.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"148-155"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of therapeutic plasma exchange in a case of severe, generalised canine pemphigus foliaceus. 血浆置换治疗严重全身性犬叶状天疱疮1例疗效观察。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-12-04 DOI: 10.1111/vde.13218

Kaitlyn Bello Edmonds, Jiwoong Her, Catherine Langston, Ryan Jennings, Sandra Diaz

引用次数: 0

Successful treatment of sebaceous adenitis with oclacitinib and low-dose prednisolone in a dog. 奥拉西替尼和低剂量强的松龙成功治疗犬皮脂腺炎。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-11-15 DOI: 10.1111/vde.13216

María Pérez-Aranda, César Yotti, Judith Pérez, Pedro J Ginel

引用次数: 0

Claw bed inverted squamous papilloma associated with canine papillomavirus type 2 in a dog. 狗爪床内翻性鳞状乳头状瘤与犬乳头状瘤病毒2型相关。

IF 1.9 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-10-01 DOI: 10.1111/vde.13208

Ana R Resendes, Karen E Trainor, Monali Bera, Ryan Chuang Fu Cheng, Jennifer Luff

引用次数: 0

Alopecia X in a cloned Pomeranian dog. 克隆博美犬的 X 型脱发症。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-02 DOI: 10.1111/vde.13234

Sébastien Deleporte, Pascal Prelaud, Catherine Laffort

引用次数: 0

Veterinary Dermatology Sustainability group. 兽医皮肤病学可持续发展小组。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-31 DOI: 10.1111/vde.13237

Monika Linek, Mar Bardagi Admetlla, Ivan Ravera, Tati Lima, Geneviève Marignac, Ronnie Kaufmann, Anette Loeffler, Nina Thom

引用次数: 0

Subcutaneous panniculitis-like T-cell lymphoma: Morphological, immunophenotypical and clonality assessment in six cats. 皮下脂膜炎样T细胞淋巴瘤：六只猫的形态学、免疫表型和克隆性评估。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-10-31 DOI: 10.1111/vde.13211

Paola Roccabianca, Silvia Dell'Aere, Giancarlo Avallone, Clarissa Zamboni, Walter Bertazzolo, Luca Crippa, Chiara Giudice, Mario Caniatti, Verena K Affolter

{"title":"Subcutaneous panniculitis-like T-cell lymphoma: Morphological, immunophenotypical and clonality assessment in six cats.","authors":"Paola Roccabianca, Silvia Dell'Aere, Giancarlo Avallone, Clarissa Zamboni, Walter Bertazzolo, Luca Crippa, Chiara Giudice, Mario Caniatti, Verena K Affolter","doi":"10.1111/vde.13211","DOIUrl":"10.1111/vde.13211","url":null,"abstract":"Background: Primary cutaneous lymphoma represents 0.2%-3% of all feline lymphomas, with nonepitheliotropic lymphomas being the most common. In humans and dogs, subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a primary nonepitheliotropic lymphoma with a T-cell phenotype developing in the subcutis and often mimicking inflammation.Objective: The aim of this report is to describe pathological, phenotypical and clonal features of SPTCL in cats.Animals: Six cats with SPTCL were included in this study.Materials and methods: Skin biopsies were formalin-fixed, routinely processed and stained. Histological and immunohistochemical investigation for anti-CD18, CD204, CD79a, CD20, CD3, FeLVp27and FeLVgp70 and clonality assessment were performed.Results: Four male and two female domestic shorthair cats, mean age 11.2 years, developed SPTCL in the abdominal (three), inguinal (two) and thoracic (one) regions. Variably pleomorphic neoplastic lymphoid cells were present in the panniculus in percentages, expanding the septa (six of six) and extending into fat lobules in one of six cats. Tumours were associated with elevated numbers of neutrophils (five of six), lesser macrophages (six of six) and variable necrosis (six of six). Neoplastic cells expressed CD3+ (six of six), with clonal T-cell receptor rearrangement detected in five of six cats.Conclusions and clinical relevance: This is the first description of SPTCL in cats. Lesions can be confused with panniculitis, leading to delay in diagnosis and therapy. Awareness of this neoplastic disease is relevant to avoid misdiagnoses and to gain greater knowledge about the disease in cats.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"207-218"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tumour necrosis factor-α induces C-C motif chemokine ligand 5 production in canine keratinocytes. 肿瘤坏死因子-α诱导犬角质形成细胞产生 C-C motif 趋化因子配体 5。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-12-18 DOI: 10.1111/vde.13227

Kaho Takahashi, Taiga Okazawa, Tomoaki Shingaki, Keiko Furuya, Junpei Kimura, Keitaro Ohmori

{"title":"Tumour necrosis factor-α induces C-C motif chemokine ligand 5 production in canine keratinocytes.","authors":"Kaho Takahashi, Taiga Okazawa, Tomoaki Shingaki, Keiko Furuya, Junpei Kimura, Keitaro Ohmori","doi":"10.1111/vde.13227","DOIUrl":"10.1111/vde.13227","url":null,"abstract":"Background: C-C motif chemokine ligand (CCL)5 induces skin inflammation in healthy dogs. In addition, CCL5 is overexpressed in the skin of experimental models of canine atopic dermatitis (cAD). Tumour necrosis factor (TNF)-α has been shown to be upregulated in cAD. However, it remains unclear whether TNF-α induces CCL5 production in canine keratinocytes.Hypothesis/objectives: To determine the effect of TNF-α on CCL5 production in canine keratinocyte culture and investigate possible synergy with interferon (IFN)-γ and interleukin (IL)-4.Materials and methods: CCL5 protein concentrations were measured by enzyme-linked immunosorbent assay (ELISA) in the culture supernatant of a cell line of canine progenitor epidermal keratinocyte (CPEK) cells stimulated with TNF-α with or without inhibitors of the TNF receptor signalling pathway. CCL5 protein concentrations also were measured in CPEK cells stimulated with TNF-α in the absence or presence of IFN-γ, a T-helper (Th)1-type cytokine, and/or IL-4, a Th2-type cytokine.Results: TNF-α increased CCL5 production in CPEK cells in time- and dose-dependent manners. Inhibitors of the TNF receptor signalling pathway diminished CCL5 production. Although neither IFN-γ nor IL-4 alone induced CCL5 production in CPEK cells, the combination of TNF-α and IFN-γ, and not IL-4, synergistically enhanced CCL5 production in these cells.Conclusions and clinical relevance: TNF-α may be involved in skin inflammation in dogs by promoting CCL5 production in keratinocytes. Furthermore, the synergistic effect of TNF-α and IFN-γ suggests that the local Th1-type milieu may aggravate skin inflammation. Further studies are required to elucidate the role of TNF-α-induced CCL5 production of keratinocytes in the pathogenesis of cAD.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"219-225"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimal microneedle length for hair regrowth in hair cycle arrest (alopecia X) in six dogs. 6只狗毛发周期阻滞(X型脱发)中毛发再生的最佳微针长度。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-12-06 DOI: 10.1111/vde.13219

Yeong-Hun Kang, Min-Sun Kim, Soh-Yoon Kang, Jae-Eun Hyun, Cheol-Yong Hwang

{"title":"Optimal microneedle length for hair regrowth in hair cycle arrest (alopecia X) in six dogs.","authors":"Yeong-Hun Kang, Min-Sun Kim, Soh-Yoon Kang, Jae-Eun Hyun, Cheol-Yong Hwang","doi":"10.1111/vde.13219","DOIUrl":"10.1111/vde.13219","url":null,"abstract":"Background: Hair cycle arrest (HCA) is a chronic alopecic disorder in dogs. Clinical responses vary and are often insufficient. Microneedling (MN) has been used as a successful treatment for HCA in dogs; ideal protocols have not yet been established.Objectives: The objective of the study was to compare the efficacy and safety of three needle lengths for MN in dogs with HCA.Animals: Six unrelated client-owned dogs, including five Pomeranians and one mixed-breed dog, diagnosed with HCA.Materials and methods: Individual alopecic sites were divided into three sections. For each section, different lengths of needles (1, 2 and 3 mm) were used. Efficacy and safety were evaluated at 1, 3 and 6 months. Treated sections were monitored for 20 months.Results: Three months after treatment with 3 mm needles, all sections showed hair regrowth. There was no hair regrowth in two of six sections treated with 2 mm needles, and four of six sections did not show a response to treatment with 1 mm needles. Two dogs developed transient pruritus. Five of six dogs had recurrent hair loss between 5 and 16 months of follow-up.Conclusion and clinical relevance: Microneedling using longer needles stimulated better hair regrowth in dogs with HCA. Alopecia relapsed in most dogs and minor pruritus occurred in some dogs.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"184-193"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0