Julie Lefrançois, Colombe Otis, Maxim Moreau, Marike Visser, Lauren Bessey, Andrea Gonzales, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Eric Troncy, Frédéric Sauvé
{"title":"Comparison of intradermal and serum testing for environmental allergen-specific immunoglobulin E determination in a laboratory colony of cats with naturally acquired atopic syndrome.","authors":"Julie Lefrançois, Colombe Otis, Maxim Moreau, Marike Visser, Lauren Bessey, Andrea Gonzales, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Eric Troncy, Frédéric Sauvé","doi":"10.1111/vde.13232","DOIUrl":"10.1111/vde.13232","url":null,"abstract":"<p><strong>Background: </strong>Allergen testing is used to select antigens included in the desensitisation vaccine. Intradermal skin test (IDT) is the gold standard in cats, yet allergen-specific immunoglobulin (Ig)E serological testing (ASIS) is often used. Feline data are lacking regarding the agreement between IDT and ASIS results.</p><p><strong>Hypothesis/objectives: </strong>The first objective of the study was to establish a colony of cats with naturally acquired feline atopic syndrome (FAS). Further objectives were to define their hypersensitivity disorder to detail the allergen tests results, and to assess similarity between the allergen tests.</p><p><strong>Animals: </strong>Thirty-five cats with FAS and 10 control cats.</p><p><strong>Materials and methods: </strong>Enrolled cats went through a five phase-screening and quarantine process before joining the colony. An elimination diet trial was performed on all FAS cats. ASIS and IDT were consecutively performed on all cats under sedation.</p><p><strong>Results: </strong>Reactions to 34 allergens were compiled for the 45 cats. Global sensitivity and specificity of ASIS were 34.7% and 78.9%, respectively. Only flea (ICC = 0.26, p = 0.040) and Dermatophagoides pteronyssinus (ICC = 0.48, p < 0.001) allergens had a significant intraclass correlation (weak agreement). Two FAS cats had negative tests including one cat with a concomitant food allergy.</p><p><strong>Conclusions and clinical relevance: </strong>This study depicts the first reported colony of cats with naturally acquired FAS. This is the first feline study to compare and show the poor agreement between allergen tests with a panel of 34 allergens. This colony also harbours two cats with FAS with negative allergen tests. These may represent the first described cats with an intrinsic form of atopic syndrome.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"305-316"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Welcome to the Tenth World Congress of Veterinary Dermatology!","authors":"","doi":"10.1111/vde.13258","DOIUrl":"https://doi.org/10.1111/vde.13258","url":null,"abstract":"","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":"35 Suppl 1 ","pages":"5"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141311816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Figurate erythema in 11 Eastern European sphynx cats.","authors":"Ekaterina Mendoza-Kuznetsova, Viktorija Lokianskiene, Ilze Matise-VanHoutan, Olesya Fiskovich, Thierry Olivry","doi":"10.1111/vde.13240","DOIUrl":"10.1111/vde.13240","url":null,"abstract":"<p><strong>Background: </strong>In humans, figurate erythema (FE) represents a heterogenous group of dermatoses with circular or serpiginous erythematous skin lesions; FE has not been reported in cats.</p><p><strong>Objectives: </strong>To report clinical and histological characteristics and outcomes of FE in sphynx cats from Baltic sea-bordering countries.</p><p><strong>Animals: </strong>Eleven client-owned sphynx cats with FE.</p><p><strong>Materials and methods: </strong>We recruited cases meeting the following criteria: (i) a sphynx breed, (ii) FE with or without scaling, (iii) a chronic, waxing-and-waning course lasting longer than a month and (iv) an absence of other skin diseases.</p><p><strong>Results: </strong>Of 11 cats, there were seven Donskoys, one Peterbald, one Ukrainian Levkoy and two presumed Canadian sphynxes; all except one were males, and the age of onset was <12 months in eight cats. Skin lesions lasted between 1.2 and 56 months, and they consisted of erythematous plaques with a linear-to-serpiginous, annular, gyrate or iris configuration predominating on the trunk and extremities. Scaling was often seen trailing the edge of the centrifugally expanding erythema. All cats were otherwise asymptomatic or mildly pruritic. Dermatophytosis was ruled out by special stains and/or fungal cultures in eight cats. Microscopic lesions revealed focal, mild-to-moderate epidermal hyperplasia and hyperkeratosis, minimal-to-mild dysplasia and subepidermal collagen smudging. Special stains were negative for dermatophytes. The clinical remission of FE was not achieved with diet changes or medical interventions; yet, a spontaneous, transient, partial or complete improvement occurred in most cats.</p><p><strong>Conclusion and clinical relevance: </strong>This is the first report of FE in sphynx cats from Eastern Europe.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"346-353"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michela De Lucia, Carolina Mendes, Giovanna Bertolini
{"title":"Bilateral pyogranulomatous otitis externa with putative cartilage destruction in a dog: A severe case of auricular chondritis?","authors":"Michela De Lucia, Carolina Mendes, Giovanna Bertolini","doi":"10.1111/vde.13252","DOIUrl":"https://doi.org/10.1111/vde.13252","url":null,"abstract":"Auricular chondritis of unknown cause was suspected in a 10‐year‐old male Bolognese dog with a five‐month history of painful bilateral nodular and ulcerative pyogranulomatous dermatitis of the pinnae with putative auricular cartilage destruction. Pain and lesions resolved with immunosuppressive doses of prednisolone, yet the condition resulted in deformity of both pinnae and external canals.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":"60 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140832119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recommendations for preparing microbiome studies for publication","authors":"Daniel O. Morris","doi":"10.1111/vde.13255","DOIUrl":"https://doi.org/10.1111/vde.13255","url":null,"abstract":"","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":"25 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140842419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christine L. Cain, Ellen White, Lindsey E. Citron, Qi Zheng, Daniel O. Morris, Elizabeth A. Grice, Charles W. Bradley
{"title":"Longitudinal evaluation of the cutaneous and rectal microbiota of German shepherd dogs with perianal fistulas undergoing therapy with ciclosporin and ketoconazole","authors":"Christine L. Cain, Ellen White, Lindsey E. Citron, Qi Zheng, Daniel O. Morris, Elizabeth A. Grice, Charles W. Bradley","doi":"10.1111/vde.13249","DOIUrl":"https://doi.org/10.1111/vde.13249","url":null,"abstract":"BackgroundPerianal fistulas are painful ulcers or sinus tracts that disproportionately affect German shepherd dogs and are proposed as a spontaneous animal model of fistulising Crohn's disease.ObjectivesTo characterise the rectal and cutaneous microbiota in German shepherd dogs with perianal fistulas and to investigate longitudinal shifts with lesion resolution during immunomodulatory therapy.AnimalsEleven German shepherd dogs with perianal fistulas and 15 healthy German shepherd dogs.Materials and MethodsAffected dogs were evaluated and swabbed at three visits, 30 days apart, while undergoing treatment with ciclosporin and ketoconazole. Healthy German shepherd dogs were contemporaneously sampled. Sites included the rectum, perianal skin and axilla. The microbiome was evaluated following sequencing of the V4 hypervariable region of the 16S ribosomal RNA (rRNA) gene.ResultsAlpha diversity was not significantly different between healthy and affected dogs at each of the three body sites (<jats:italic>p</jats:italic> > 0.5), yet rectal and perianal beta diversities from affected dogs differed significantly from those of healthy dogs at Day 0 (<jats:italic>p</jats:italic> = 0.004). Rectal and perianal relative abundance of <jats:italic>Prevotella</jats:italic> spp. increased and perianal <jats:italic>Staphylococcus</jats:italic> spp. relative abundance decreased in affected dogs over time, coincident with lesion resolution.Conclusions and Clinical RelevanceChanges in lesional cutaneous and rectal microbiota occur in German shepherd dogs with perianal fistulas and shift over time with lesion resolution during immunomodulatory therapy. Further investigations of the role of cutaneous and enteric microbiota in the pathogenesis of perianal fistulas, and whether manipulation of microbial populations may ameliorate disease, are needed.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":"21 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John S Munday, Hanna J Klobukowska, Karen Nicholson
{"title":"Amplification of Ovis aries papillomavirus type 2 DNA from an ovine cutaneous fibropapilloma.","authors":"John S Munday, Hanna J Klobukowska, Karen Nicholson","doi":"10.1111/vde.13207","DOIUrl":"10.1111/vde.13207","url":null,"abstract":"<p><p>Seven of 60 Perendale sheep within a flock developed single or multiple exophytic masses on their distal hind limbs. A mass was excised from one sheep and histological evaluation revealed epidermal and mesenchymal proliferation, papillomavirus-induced keratinocyte changes and marked keratohyalin clumping. Ovis aries papillomavirus type 2 DNA sequences were amplified using PCR.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"226-229"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10222835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giordana Zanna, Francesca Abramo, Barbara Contiero, Eric Zini, Francesco Albanese, Elena Borio, Francesco Godizzi, Fabiano Necci, Luca Luciani, Paola Roccabianca
{"title":"Dermoscopic findings and comparison of usefulness of longitudinal versus transversal sections in the histological diagnosis of alopecia X.","authors":"Giordana Zanna, Francesca Abramo, Barbara Contiero, Eric Zini, Francesco Albanese, Elena Borio, Francesco Godizzi, Fabiano Necci, Luca Luciani, Paola Roccabianca","doi":"10.1111/vde.13212","DOIUrl":"10.1111/vde.13212","url":null,"abstract":"<p><strong>Background: </strong>A combination of dermoscopic and histological findings may provide useful information for the diagnosis of hair follicle diseases. However, there are no studies on dermoscopic-histopathological correlations in dogs affected by alopecia X, and comparison of longitudinal versus transversal sectioning of skin biopsy specimens in the assessment of this hair loss disorder has not been thoroughly investigated.</p><p><strong>Hypothesis/objectives: </strong>The aim of this study was to correlate dermoscopic and histological features using both longitudinal and transversal sectioning of skin biopsy samples to gain additional information for the diagnosis of alopecia X.</p><p><strong>Animals: </strong>Nineteen Pomeranian dogs affected by alopecia X and five healthy Pomeranians as controls.</p><p><strong>Materials and methods: </strong>Dermoscopic-histological correlation was performed within the diseased group, whereas histological comparisons against controls. The demographic and clinical characteristics also were related to the histological findings.</p><p><strong>Results: </strong>The dermoscopic findings revealed scattered, thinned, short hairs mixed with amorphous keratoseborrhoeic-like material (follicular plugging), perifollicular and intrafollicular scaling, and hyperpigmentation varying from pinpoint black spots to a diffuse texture. Dermoscopic findings correlated with histological findings for selected qualitative and quantitative findings. The usefulness of transversal sections was demonstrated in accurately determining the hair follicular density and counts, growth arrest phases and in identifying mineralisation of hair follicle basement membrane when compared to the longitudinal. Conversely, no correlations between histological findings and demographic and clinical characteristics were detected.</p><p><strong>Conclusions and clinical relevance: </strong>These data provide evidence of the usefulness of dermoscopic evaluation as an accessory diagnostic tool and of transversal sections of skin biopsies as complementary to the diagnosis of alopecia X.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"126-137"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M O Dumitrache, Z Kalmár, S Roumegous, K Charmes, M Delverdier, J L Le Net, M C Cadiergues
{"title":"Feline straelensiosis: Clinical and histopathological description of a case and first genetic characterisation of Straelensia cynotis.","authors":"M O Dumitrache, Z Kalmár, S Roumegous, K Charmes, M Delverdier, J L Le Net, M C Cadiergues","doi":"10.1111/vde.13214","DOIUrl":"10.1111/vde.13214","url":null,"abstract":"<p><p>Straelensia cynotis is a trombidioid mite that causes painful, usually nonpruritic nodular dermatitis mainly in the dorsal region of dogs. This case report describes the first observation of feline straelensiosis in Europe with clinicopathological findings. Molecular characterisation of the parasite was performed and compared with mites collected from dogs.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"234-237"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89719750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Canine cutaneous lupus erythematosus with prominent interdigital lesions in two greyhounds.","authors":"Eleanor K Wyatt, Vanessa Schmidt, Sara Legnani","doi":"10.1111/vde.13220","DOIUrl":"10.1111/vde.13220","url":null,"abstract":"<p><p>Canine cutaneous lupus erythematosus (CCLE) is a well-described, yet uncommon, autoimmune disease which can present clinically with different variants. This case report describes the clinical and histopathological presentation, and treatment response, of CCLE affecting a novel location, the interdigital skin, in two unrelated greyhounds.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"242-246"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}