Canine exfoliative cutaneous lupus erythematosus in two mixed breed littermates.

IF 1.9 3区农林科学 Q3 DERMATOLOGY

Veterinary dermatology Pub Date : 2024-09-30 DOI:10.1111/vde.13301

Mirabela Oana Dumitrache, Aurora Livia Ursache, Corina Toma, Andrada Negoescu, Stefan Jonas Rietmann, Tosso Leeb, Marie-Christine Cadiergues

引用次数: 0

Abstract

Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.

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两只混血幼犬患上犬剥脱性皮肤红斑狼疮。

犬剥脱性皮肤红斑狼疮（ECLE）是犬皮肤红斑狼疮中最罕见的变异型，具有很强的品种倾向性。本报告介绍了两例混血犬ECLE病例的临床、组织病理学和免疫组化特征，并证实了预期的基因突变。报告还记录了对奥克替尼的治疗反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary dermatology 农林科学-兽医学

CiteScore

3.20

自引率

21.40%

发文量

审稿时长

12-24 weeks

期刊介绍： Veterinary Dermatology is a bi-monthly, peer-reviewed, international journal which publishes papers on all aspects of the skin of mammals, birds, reptiles, amphibians and fish. Scientific research papers, clinical case reports and reviews covering the following aspects of dermatology will be considered for publication: -Skin structure (anatomy, histology, ultrastructure) -Skin function (physiology, biochemistry, pharmacology, immunology, genetics) -Skin microbiology and parasitology -Dermatopathology -Pathogenesis, diagnosis and treatment of skin diseases -New disease entities