Turkish Journal of Ophthalmology最新文献_第7页

Vitiligo in a Patient Receiving Adalimumab for Idiopathic Uveitis 接受阿达木单抗治疗特发性葡萄膜炎患者的白癜风

Turkish Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.4274/tjo.galenos.2024.04575

M. Değirmenci, F. Yalçındağ

{"title":"Vitiligo in a Patient Receiving Adalimumab for Idiopathic Uveitis","authors":"M. Değirmenci, F. Yalçındağ","doi":"10.4274/tjo.galenos.2024.04575","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2024.04575","url":null,"abstract":"In recent years, adalimumab has been increasingly used in the chronic treatment of non-infectious uveitis. This case report aimed to describe a drug-induced adverse event in a 34-year-old man who presented with blurred vision and floaters in the right eye and was being treated for intermediate uveitis. The patient had started topical treatment with a diagnosis of uveitis at another center. Best corrected visual acuity at presentation was 0.8 (decimal) in the right eye and 1.0 in the left eye. On examination, the anterior chamber in the right eye was clear, with anterior vitreous cells and mild haze, and snow banking and vitreous opacities in the inferior periphery. Fluorescein angiography (FA) showed hyperfluorescence in the right disc and leakage in the inferior periphery. As the inflammation did not resolve with local treatment, systemic cyclosporine was administered, after which the patient exhibited vomiting and weakness. Cyclosporine was discontinued and adalimumab treatment was started. On examination 5 months later, bilateral vitreous cells and mild vitreous opacity were noted, and FA showed mild leakage in the inferior periphery bilaterally. In addition, a depigmented patchy vitiligo lesion was observed on the chin. Due to the persistence of intraocular inflammation and on the recommendation of the dermatology clinic, adalimumab treatment was continued and topical tacrolimus was started for the lesion. On examination 3 months later, the inflammatory findings had resolved and there was no progression of the vitiligo lesion. The patient’s treatment was continued. Taken together with the previous literature findings, no pathology was found in the patient’s systemic examination, suggesting that this lesion was a side effect of the treatment. Ophthalmologists should be alert for this side effect in patients receiving adalimumab.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"21 10","pages":"112 - 115"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140797007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Contact Lenses and Visual Development in Pediatric Aphakia 隐形眼镜的管理与小儿无晶体眼的视觉发育

Turkish Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.4274/tjo.galenos.2023.56252

T. Şengör, Tuğba Gençağa Atakan

引用次数: 0

Is Glaucoma a Two-Pressure-Related Optic Neuropathy? A Systematic Review and Meta-Analysis 青光眼是双压相关性视神经病变吗？系统回顾与元分析

Turkish Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.4274/tjo.galenos.2024.66267

T. Hoang, Bui Van Anh, P. Subramanian

引用次数: 0

Scleral Contact Lens to Preserve a Corneal Graft in Chronic Lagophthalmos 巩膜接触镜为慢性眼袋患者保留角膜移植体

Turkish Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.4274/tjo.galenos.2024.68253

Zeynep Özbek, Işıl Kefeli

引用次数: 0

A Rare Association: Neovascular Glaucoma Accompanying Anterior Chamber Synchysis Scintillans 罕见的关联:新血管性青光眼伴前房闪烁性合成。

Turkish Journal of Ophthalmology Pub Date : 2024-02-22 Epub Date: 2023-11-27 DOI: 10.4274/tjo.galenos.2023.39016

Serdar Bayraktar, Atakan Acar, Mehmet Ali Şekeroğlu

引用次数: 0

Indocyanine Green Angiography. 吲哚菁绿血管造影

Turkish Journal of Ophthalmology Pub Date : 2024-02-22 DOI: 10.4274/tjo.galenos.2023.89735

Faik Gelişken

引用次数: 0

Using the Amsler Grid Test for Age-Related Macular Degeneration Screening. 使用阿姆斯勒网格测试筛查老年性黄斑变性。

Turkish Journal of Ophthalmology Pub Date : 2024-02-22 DOI: 10.4274/tjo.galenos.2023.04238

Seyyide Ayşenur Kuzucu Üşümüş, Ayşe Gül Koçak Altıntaş, Ayşe Özdemir, Cenk Aypak

{"title":"Using the Amsler Grid Test for Age-Related Macular Degeneration Screening.","authors":"Seyyide Ayşenur Kuzucu Üşümüş, Ayşe Gül Koçak Altıntaş, Ayşe Özdemir, Cenk Aypak","doi":"10.4274/tjo.galenos.2023.04238","DOIUrl":"10.4274/tjo.galenos.2023.04238","url":null,"abstract":"Objectives: To evaluate the use of the Amsler grid test (AGT) in screening for age-related macular degeneration (AMD), one of the most common causes of blindness, in primary healthcare settings.Materials and methods: The AGT was applied to 700 eyes of 355 people aged 50 and over who applied to a family health center in Ankara and had no eye complaints. The test was considered positive if the lines on the AGT card were seen as broken or curved, there was a difference in shape or size between the squares, or a color change or blurring was described in any area. An ophthalmologist was consulted if the AGT was positive in one or both eyes. Patients considered suitable by ophthalmologists were evaluated with optical coherence tomography. AGT results were compared with ophthalmologist examination and tomography findings in terms of AMD detection.Results: The AGT was positive in 97 (13.9%) and negative in 603 (86.1%) out of 700 eyes included in the study. A total of 184 eyes, 79 with a positive AGT and 105 eyes with a negative test, were evaluated by an ophthalmologist. As a result of examinations and tests performed by ophthalmologists, AMD was detected in a total of 67 eyes: 42 of 79 eyes with positive AGT and 25 of 105 eyes with negative AGT but referred to an ophthalmologist for different reasons. In our study, the AGT had 62.7% sensitivity and 68.4% specificity.Conclusion: The AGT is an inexpensive and easily applicable test. Although moderate sensitivity and specificity were found in our study; further studies are needed to evaluate the suitability of its use for AMD screening in primary care with limited facilities.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"54 1","pages":"11-16"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10895168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impression Cytologic Evaluation of the Conjunctiva in Patients Treated with Topical 1% Voriconazole 局部1%伏立康唑治疗患者结膜的印象细胞学评价。

Turkish Journal of Ophthalmology Pub Date : 2024-02-22 Epub Date: 2023-11-27 DOI: 10.4274/tjo.galenos.2023.20268

Cumali Değirmenci, Melis Palamar, Zübeyde Ekin, Özlem Barut Selver, Ali Veral, Ayşe Yağcı

{"title":"Impression Cytologic Evaluation of the Conjunctiva in Patients Treated with Topical 1% Voriconazole","authors":"Cumali Değirmenci, Melis Palamar, Zübeyde Ekin, Özlem Barut Selver, Ali Veral, Ayşe Yağcı","doi":"10.4274/tjo.galenos.2023.20268","DOIUrl":"10.4274/tjo.galenos.2023.20268","url":null,"abstract":"Objectives: The aim of the present study was to evaluate any conjunctival metaplastic changes by impression cytology in patients who underwent topical 1% voriconazole treatment for severe fungal keratitis.Materials and methods: The study was conducted at Ege University Faculty of Medicine, Departments of Ophthalmology and Medical Pathology. Patients who were treated with 1% topical voriconazole for fungal keratitis for at least 3 months were included. The used topical voriconazole treatment was initiated as one drop every hour and was tapered according to clinical improvement in all patients. Treatment was continued 4 times a day for at least 3 months. Impression cytology samples were collected at least 3 months after cessation of topical voriconazole from the affected eyes and from the fellow eyes as a control group. Collected specimens were transferred to the pathology department for evaluation and grading (Nelson’s grading system).Results: The mean age of the patients was 57.68±17.32 years (range, 22-87 years). The impression cytology grade of the inferior bulbar conjunctiva was 1.73±0.77 (range, 0-3) in the study group and 1.19±0.98 (range, 0-3) in the control group (p=0.03). The impression cytology grade of the temporal bulbar conjunctiva was 1.69±0.73 (range, 0-3) in the study group and 1.15±0.88 (range, 0-3) in the control group (p=0.02). The impression cytology grades of the nasal and superior bulbar conjunctiva did not differ statistically (p values 0.13 and 0.17, respectively).Conclusion: Topical voriconazole is an effective broad-spectrum antifungal drug, but it induces conjunctival squamous metaplasia. Clinicians should be aware of this possible side effect of topical voriconazole and should carefully evaluate the conjunctiva of treated patients at each visit to detect possible metaplastic changes.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10895164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138441321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Embedded Episcleral Foreign Body Mimicking Nodular Anterior Scleritis. 模仿结节性前巩膜炎的嵌入式巩膜异物

Turkish Journal of Ophthalmology Pub Date : 2024-02-22 DOI: 10.4274/tjo.galenos.2023.37460

Zeynep Özbek, Banu Lebe, Mustafa Kayabaşı, Ali Osman Saatci

{"title":"Embedded Episcleral Foreign Body Mimicking Nodular Anterior Scleritis.","authors":"Zeynep Özbek, Banu Lebe, Mustafa Kayabaşı, Ali Osman Saatci","doi":"10.4274/tjo.galenos.2023.37460","DOIUrl":"10.4274/tjo.galenos.2023.37460","url":null,"abstract":"A 56-year-old man was referred to our clinic for unilateral nodular scleritis unresponsive to systemic corticosteroids. A localized, nodular hyperemia on the nasal bulbar conjunctiva surrounding a central cyst-like lesion together with vascular engorgement was observed on slit-lamp examination of the left eye. No abnormal fundoscopic findings were noted. Surgical exploration revealed an embedded episcleral brown colored, soft to touch, splinter-like organic foreign body (FB) which was confirmed by the histopathological examination. Nodular hyperemia resolved during the postoperative follow-up period, and mild scar tissue accompanied by scleral thinning developed in the left nasal bulbar conjunctiva. Ocular injury associated with FBs may cause significant ocular morbidity depending on the nature and location of the FB. Severe visual disability may occur if left untreated. Subconjunctival FBs are rare and may present with a clinical picture mimicking episcleritis or scleritis. History of trauma involving a FB should always be assessed for an accurate differential diagnosis and appropriate management of patients with anterior scleritis.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"54 1","pages":"46-48"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10895169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demographic, Etiological, and Clinical Characteristics of Eyelid Lacerations. 眼睑裂伤的人口、病因和临床特征

Turkish Journal of Ophthalmology Pub Date : 2024-02-22 DOI: 10.4274/tjo.galenos.2023.05684

Emine Doğan, Şule Bahadır Coşkun, Büşra Güner Sönmezoğlu, Gürsoy Alagöz

{"title":"Demographic, Etiological, and Clinical Characteristics of Eyelid Lacerations.","authors":"Emine Doğan, Şule Bahadır Coşkun, Büşra Güner Sönmezoğlu, Gürsoy Alagöz","doi":"10.4274/tjo.galenos.2023.05684","DOIUrl":"10.4274/tjo.galenos.2023.05684","url":null,"abstract":"Objectives: To evaluate the demographic, etiological, and accompanying clinical factors in eyelid lacerations (EL).Materials and methods: The records of patients who presented to our clinic between 2018 and 2022 with eyelid trauma were retrospectively reviewed. Age, gender, cause of injury, clinical findings, accompanying ocular findings, and additional complications were analyzed.Results: The study included 135 patients (106 male, 29 female) with a mean age of 37.0±18.6 years. Among the patients, 29 (21.4%) were 18 years old or younger, 93 (68.8%) were between 19 and 64 years old, and 13 (9.6%) were 65 years old or older. EL were most caused by various sharp objects in 44 patients (33%), blunt trauma in 40 patients (30%), falls in 30 patients (22%), and traffic accidents in 21 patients (15%). Fifteen eyes (11.1%) had foreign bodies at the wound site. Thirty patients (22.2%) (20 lower eyelid, 10 upper eyelid) had accompanying canalicular lacerations. Twenty-three (17%) patients had accompanying conjunctival lacerations, 14 (10.3%) had open-globe injury, 10 (7.4%) had corneal epithelial defects, 9 (6.6%) had intravitreal hemorrhage, 6 (4.4%) had hyphema, and 5 (3.7%) had retinal detachment. Four patients had lid notching and 1 patient (0.7%) had ectropion. Five patients (3.7%) required suturing. No additional complications were observed.Conclusion: EL are more commonly seen in young adulthood and in males. The most common mechanism of injury is impact by various objects. Eyelash margin and canalicular lacerations frequently accompany these injuries. Serious ocular pathologies such as hyphema and open-globe injury can accompany eyelid trauma.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"54 1","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10895165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0