Turkish Journal of Ophthalmology最新文献_第8页

Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options. 假脱落性青光眼:临床表现和治疗选择。

Turkish Journal of Ophthalmology Pub Date : 2023-08-19 DOI: 10.4274/tjo.galenos.2023.76300

Nurşen Yüksel, Büşra Yılmaz Tuğan

{"title":"Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options.","authors":"Nurşen Yüksel, Büşra Yılmaz Tuğan","doi":"10.4274/tjo.galenos.2023.76300","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2023.76300","url":null,"abstract":"Pseudoexfoliation syndrome (PES) is one of the most common causes of open-angle glaucoma, with a higher risk of vision loss, a higher maximum and mean intraocular pressure (IOP) at diagnosis, and a wider range of IOP fluctuation compared to primary open-angle glaucoma. Patients with this syndrome have a ten-fold higher risk of developing glaucoma than the normal population. A definite diagnosis can be made by the observation of pseudoexfoliation material (PEM) on the anterior lens surface, ciliary processes, zonules, and iris. PEM deposits on the zonules may explain the clinically observed zonular weakness and lens subluxation or dislocation. An increased incidence of cataract development is also associated with PES. There is growing evidence for systemic associations of PES with peripheral, cardiovascular, and cerebrovascular system diseases, Alzheimer's disease, hearing loss, and increased plasma homocysteine levels. Indications for surgery are markedly more common in patients with pseudoexfoliation glaucoma than primary open-angle glaucoma. The goal of this article is to review the latest perspectives on the clinical features, therapy, and systemic associations of this clinically and biologically challenging disease.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f0/36/TJO-53-247.PMC10442753.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10176214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conjunctival Impression Cytology and Tear Film Changes in Sarcoidosis: A Subjective and Objective Diagnosis Study. 结节病结膜印模细胞学和泪膜变化的主客观诊断研究。

Turkish Journal of Ophthalmology Pub Date : 2023-08-19 DOI: 10.4274/tjo.galenos.2022.58153

Özgür Eroğul, Aydın Balcı, Hamidu Hamisi Gobeka, Neriman Efe, Müberra Akdoğan, Ayşe Yeşim Oral, Mustafa Doğan, Çiğdem Özdemir, Murat Kaşıkçı, Sinan Saraçlı

{"title":"Conjunctival Impression Cytology and Tear Film Changes in Sarcoidosis: A Subjective and Objective Diagnosis Study.","authors":"Özgür Eroğul, Aydın Balcı, Hamidu Hamisi Gobeka, Neriman Efe, Müberra Akdoğan, Ayşe Yeşim Oral, Mustafa Doğan, Çiğdem Özdemir, Murat Kaşıkçı, Sinan Saraçlı","doi":"10.4274/tjo.galenos.2022.58153","DOIUrl":"10.4274/tjo.galenos.2022.58153","url":null,"abstract":"Objectives: To evaluate sarcoidosis-induced tear film changes using subjective and objective diagnostic tests, particularly conjunctival impression cytology (IC), and to compare the results with healthy individuals.Materials and methods: This study evaluated clinical data collected between January 2019 and January 2021 from 57 right eyes of 57 sarcoidosis patients without ocular involvement (Group 1) and 33 right eyes of 33 healthy individuals with similar demographic characteristics (Group 2). The Schirmer I test, tear break-up time (TBUT), fluorescein staining, and conjunctival IC were all performed as part of the conjunctival and corneal examinations following a thorough ophthalmological examination. The Ocular Surface Disease Index (OSDI) was used to assess subjective ocular symptoms.Results: The mean ages in Groups 1 and 2 were 49.26±3.18 and 51.91±2.89 years, respectively (p=0.720). The mean Schirmer I test, TBUT, and OSDI scores differed significantly (p<0.05 for all), with Group 1 having a significantly higher percentage of dry eyes than Group 2. Group 1 had significantly higher Nelson's grading system grades than Group 2 based on conjunctival IC analysis (p=0.001). There were no significant differences in visual acuity (p=0.17) or intraocular pressure (p=0.14) between groups.Conclusion: Sarcoidosis patients had significantly higher Nelson grades in conjunctival IC, as well as significantly higher percentages of dry eye as determined by the Schirmer I test, TBUT, and OSDI. Reduced tear quantity and quality may destabilize the tear film layer, resulting in a variety of ocular symptoms.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/81/TJO-53-200.PMC10442751.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10179166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Macular Imaging Characteristics in Children with Myelinated Retinal Nerve Fiber and High Myopia Syndrome. 有髓视网膜神经纤维和高度近视综合征患儿的黄斑影像学特征。

Turkish Journal of Ophthalmology Pub Date : 2023-08-19 DOI: 10.4274/tjo.galenos.2023.27612

Almila Sarıgül Sezenöz, Sibel Oto, İmren Akkoyun, Sezin Akça Bayar, Gürsel Yılmaz, Meriç Yavuz Çolak

{"title":"Macular Imaging Characteristics in Children with Myelinated Retinal Nerve Fiber and High Myopia Syndrome.","authors":"Almila Sarıgül Sezenöz, Sibel Oto, İmren Akkoyun, Sezin Akça Bayar, Gürsel Yılmaz, Meriç Yavuz Çolak","doi":"10.4274/tjo.galenos.2023.27612","DOIUrl":"10.4274/tjo.galenos.2023.27612","url":null,"abstract":"Objectives: To investigate the macular imaging features in patients with unilateral myelinated retinal nerve fiber (MRNF) and high myopia syndrome.Materials and methods: Six patients with unilateral MRNF and high myopia syndrome and 13 myopic controls were enrolled in this study. Spectral domain (SD) optical coherence tomography (OCT), SD enhanced depth imaging OCT, and OCT angiography (OCTA) imaging results of MRNF-affected eyes were compared with the fellow eyes and myopic controls.Results: All patients had abnormal foveal reflex and/or ectopia. No significant difference in retinal thickness parameters were noted between the groups. In OCT scans, posterior vitreous detachment (PVD) was observed in 4 out of the 6 MRNF-affected eyes. Regarding OCTA parameters, only a significant increase in acircularity index was noted in myelinated eyes (p=0.01).Conclusion: All patients demonstrated normal foveal contours, macular structure, and OCTA features except for a higher acircularity index. The incidence of PVD was notably increased in the myelinated eyes.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/f1/TJO-53-234.PMC10442755.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10176209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Applications of Mitomycin C in Cornea and External Disease. 丝裂霉素C在角膜及外部疾病中的应用。

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2023.97932

Marcos A Crespo, Christopher J Rapuano, Zeba A Syed

引用次数: 0

Regional Analysis of Inner Retinal Layer Changes in Multiple Sclerosis with and without Optic Neuritis. 伴与不伴视神经炎的多发性硬化症视网膜内层改变的区域分析。

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2023.81486

Belma Kayhan, Şükrü Sevinçli, Nur Demir, Serkan Demir, Murat Sönmez

{"title":"Regional Analysis of Inner Retinal Layer Changes in Multiple Sclerosis with and without Optic Neuritis.","authors":"Belma Kayhan, Şükrü Sevinçli, Nur Demir, Serkan Demir, Murat Sönmez","doi":"10.4274/tjo.galenos.2023.81486","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2023.81486","url":null,"abstract":"Objectives: The study aimed to investigate inner retinal changes in multiple sclerosis (MS) patients by comparing them with healthy controls. The study also aimed to assess regional differences of inner retinal layer involvement in eyes with and without optic neuritis (ON).Materials and methods: This retrospective, cross-sectional study consisted of 141 eyes of 74 relapsing-remitting MS patients and 80 eyes of 40 healthy controls. The study group was separated into two subgroups according to the presence of ON history. Peripapillary retinal nerve fiber layer (pRNFL) thickness, total macular thickness, and thicknesses of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and inner nuclear layer were compared between the MS and healthy control groups and between eyes with and without ON history.Results: Mean pRNFL, total macular, mRNFL, GCL, and IPL thicknesses were significantly thinner in the MS group than in the control group (p<0.001) and in eyes with ON compared to those without ON (p<0.05). Comparison of inner retinal layer thicknesses in the inner 3-mm ring subfields of the ETDRS grid revealed significant thinning in all subfields of the GCL and IPL of eyes with ON (p<0.05). The inferior subfield demonstrated the highest difference.Conclusion: The study demonstrated that GCL and IPL thinning is a robust and reliable biomarker in all MS patients. The thinning was significantly greater in eyes with ON than in eyes without ON. The study also documented that the inferior region showed significantly greater GCL and IPL thinning in eyes with previous ON attacks.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/1d/TJO-53-169.PMC10286840.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9710235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macular and Peripapillary Vascular Densities in Non-Glaucomatous Eyes of Patients with Unilateral Glaucoma. 单侧青光眼患者非青光眼的黄斑和乳头周围血管密度。

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2022.68302

Sirel Gür Güngör, Şefik Cezairlioğlu, Ahmet Akman, Ümit Ekşioğlu, Almila Sarıgül Sezenöz, Meriç Yavuz Çolak

{"title":"Macular and Peripapillary Vascular Densities in Non-Glaucomatous Eyes of Patients with Unilateral Glaucoma.","authors":"Sirel Gür Güngör, Şefik Cezairlioğlu, Ahmet Akman, Ümit Ekşioğlu, Almila Sarıgül Sezenöz, Meriç Yavuz Çolak","doi":"10.4274/tjo.galenos.2022.68302","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2022.68302","url":null,"abstract":"Objectives: Our purpose was to investigate vascular alterations in the non-glaucomatous eyes of patients with unilateral primary open angle glaucoma using optical coherence tomography angiography and to evaluate the role of vascular damage in glaucoma pathogenesis.Materials and methods: This cross-sectional study included 60 eyes of 30 patients with unilateral glaucoma (63.4±8.8 years) and 30 eyes of 30 healthy subjects (65.6±9.1 years). Three groups were formed: group A, affected eyes of unilateral glaucoma patients; Group B, non-glaucomatous eyes of unilateral glaucoma patients; and group C, healthy controls.Results: When group A was compared with groups B and C, significant differences were detected in rim area, cup volume, mean cup/disc ratio, and retinal nerve fiber layer thickness parameters (p<0.001 for all). No significant difference was detected between groups B and C (p>0.05 for all). In peripapillary and macular vessel density (VD) comparisons, all parameters except intradisc VD were found to be lower in group A (p<0.0167 for all). No statistically significant difference was detected between groups B and C (p>0.05 for all).Conclusion: The VD values in eyes with glaucoma were found to be lower than in the other two groups. However, no difference was observed between the non-glaucomatous eyes of glaucoma patients and those of healthy individuals. Thus, the results did not support our hypothesis that VD alterations would be observed in the fellow eyes of patients with unilateral glaucoma if the vascular pathway were responsible in the pathogenesis of glaucoma.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f0/bd/TJO-53-154.PMC10286842.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9702069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Concurrent Acute Macular Neuroretinopathy and Paracentral Acute Middle Maculopathy Following Pfizer-BioNTech COVID-19 Vaccination. 辉瑞- biontech新冠肺炎疫苗接种后并发急性黄斑神经视网膜病变和中央旁急性中期黄斑病变1例

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2023.65118

Jale Menteş, Serhad Nalçacı, Cumali Değirmenci

引用次数: 0

A Rare Case Report of Eight Syndrome Secondary to Syringomyelia Associated with Type I Chiari Malformation. 1型Chiari畸形伴脊髓空洞继发综合征8例报道。

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2023.19054

Dilek Top Kartı, Pelin Kıyat, Ömer Kartı, Neşe Çelebisoy

{"title":"A Rare Case Report of Eight Syndrome Secondary to Syringomyelia Associated with Type I Chiari Malformation.","authors":"Dilek Top Kartı, Pelin Kıyat, Ömer Kartı, Neşe Çelebisoy","doi":"10.4274/tjo.galenos.2023.19054","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2023.19054","url":null,"abstract":"Eight syndrome is defined as the combination of a unilateral conjugate gaze palsy and ipsilateral seventh cranial nerve palsy. It may occur as a result of demyelinating, vascular, infectious, or compressive lesions of the brainstem localized to the caudal pontine tegmentum. A 43-year-old woman was admitted to our clinic with complaints of headache, inability to look to the left, and weakness on the left side of her face. The complaints had begun abruptly about a month before her admission. Suboccipital decompression surgery for type I Chiari malformation had been performed 10 years earlier. Neuro-ophthalmological examination revealed left-sided horizontal gaze palsy and anisocoria. Cranial and cervical magnetic resonance images revealed cerebellar tonsillar herniation and syringomyelia, the latter of which was considered to be the cause of eight syndrome. No interventions were performed, and periodic follow-up was advised on neurosurgical consultation. Left gaze palsy and facial palsy recovered almost completely in three months, while the anisocoria persisted. Syringomyelia should be considered among the causes of horizontal gaze palsy plus ipsilateral seventh nerve palsy, termed as eight syndrome. Clinical suspicion and appropriate radiological examination can aid in the diagnosis.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/cc/TJO-53-197.PMC10286839.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9710234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lamellar Keratoplasty Using Microkeratome-Assisted Anterior Lamellar Graft in the Management of Deep Limbal Dermoid: A Case Report. 应用微角粒辅助前板层角膜移植术治疗深角膜缘皮样1例。

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2023.93027

Özlenen Ömür Uçakhan Gündüz, Ahmet Kaan Gündüz, Hilal Nalcı Baytaroğlu

引用次数: 0

Comparison of Hybrid Contact Lenses and Rigid Gas-Permeable Contact Lenses in Moderate and Advanced Keratoconus. 混合型隐形眼镜与硬质透气性隐形眼镜治疗中晚期圆锥角膜的比较。

Turkish Journal of Ophthalmology Pub Date : 2023-06-21 DOI: 10.4274/tjo.galenos.2022.82754

Yelda Yıldız Taşcı, Özge Saraç, Nurullah Çağıl, Nilüfer Yeşilırmak

{"title":"Comparison of Hybrid Contact Lenses and Rigid Gas-Permeable Contact Lenses in Moderate and Advanced Keratoconus.","authors":"Yelda Yıldız Taşcı, Özge Saraç, Nurullah Çağıl, Nilüfer Yeşilırmak","doi":"10.4274/tjo.galenos.2022.82754","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2022.82754","url":null,"abstract":"Objectives: We aimed to compare the clinical results and topographic data of the new generation hybrid contact lens (HCL) and rigid gas-permeable contact lens (RGPCL) in patients with moderate and advanced keratoconus.Materials and methods: In this prospective study, HCL users comprised group 1 and RGPCL users comprised group 2. Snellen uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and lens-corrected visual acuity (LCVA); manifest spherical-cylindrical values; corneal topography measurements (flat keratometry [K1], vertical keratometry [K2], mean K, maximum K [Kmax], central corneal thickness [CCT], and thinnest corneal thickness [TCT]); and cone location were recorded.Results: The study included 83 eyes of 51 patients in group 1 and 61 eyes of 40 patients in group 2. The groups were similar in age and gender (p>0.05). Mean LCVA (logMAR) was significantly lower than BCVA in both groups (p<0.001). The mean visual gain with contact lenses (Snellen chart) was 3.4±1.8 lines in group 1 and 4.0±2.1 lines in group 2. There was no significant difference between the two groups in BCVA, LCVA, or lines gained (p>0.05). There was also no significant difference between the two groups in terms of keratoconus stages, mean Kmax, CCT, TCT, or cone location (p>0.05), while mean UCVA (logMAR) and mean K were higher in group 2 (p<0.05). In both groups, the visual gain with lenses was higher in eyes with central cones, and there was significantly greater visual increase in group 2 (p=0.039).Conclusion: In moderate and advanced keratoconus, HCLs improved vision as much as RGPCLs and both lenses were more effective for central cones. Nevertheless, longer term of follow-up and larger numbers of patients are needed for long term follow-up results of HCL.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/9b/TJO-53-142.PMC10286838.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9702068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0