Turkish Journal of Chemistry最新文献_第10页

N-(2-Aminobenzoyl)benzotriazole Mediated Synthesis of 3-Acyl-2-alkyl(aryl)-4-hydroxyquinolines and 3-Acylamino-4(3H) quinazolinones. N-(2-氨基苯甲酰基)苯并三唑介导的 3-酰基-2-烷基(芳基)-4-羟基喹啉和 3-酰氨基-4(3H)喹唑啉酮的合成。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-16 eCollection Date: 2024-01-01 DOI: 10.55730/1300-0527.3642

İlbilge Merve Şenol, Sevtem Gökbulut Satioğlu, İlhami Çelik

引用次数: 0

Quaternized chitosan/PVA/natural bioactive agent electrospun wound scaffolds: production, characterization, and investigation of release kinetics. 季铵化壳聚糖/PVA/天然生物活性剂电纺伤口支架：生产、表征和释放动力学研究。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-16 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3633

Ezgi Eren Belgin, Cankız Gizem Delibalta

{"title":"Quaternized chitosan/PVA/natural bioactive agent electrospun wound scaffolds: production, characterization, and investigation of release kinetics.","authors":"Ezgi Eren Belgin, Cankız Gizem Delibalta","doi":"10.55730/1300-0527.3633","DOIUrl":"10.55730/1300-0527.3633","url":null,"abstract":"Quaternized chitosan (HTCC) was synthesized and characterized to increase chitosan solubility. Then HTCC was electrospun with poly (vinyl alcohol) (PVA) and prepared natural bioactive agent (Calendula officinalis) extract was loaded onto fibers for wound scaffold applications. Morphological, structural, and mechanical characterization of the produced wound scaffolds was performed and their in vitro bioactive component release behavior was investigated. As a result, it was observed that the degree of quaternization of chitosan was 0.89, and synthesized HTCC was soluble in acidic, basic, alkaline media and could be electrospun with PVA in the presence of a natural bioactive agent. The presence of HTCC increased Young's modulus and the tensile strength of the PVA scaffolds, while the presence of bioactive extract caused a decrease in Young's modulus and an increase in tensile strength. Calendula officinalis is released in a controlled and slow manner from the scaffolds within approximately 55 h. The release behavior was consistent with the Higuchi kinetic model. In this study, the effect of PVA cooperator on HTCC nanofiber production in the presence of a bioactive component was investigated for the first time. HTCC and Calendula officinalis extract were also used together for the first time in the composition of a fiber scaffold. The mechanical properties and release kinetics of these scaffolds were also investigated for the first time. According to the results, it is thought that the wound scaffolds produced have the potential to be used as a new treatment tool, especially for chronic wounds.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1529-1539"},"PeriodicalIF":1.4,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Production of gelatin fibrous mats using different nanofiber production methods for medical applications and comparison of their properties. 使用不同的纳米纤维生产方法生产医疗用明胶纤维毡并比较其特性。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-16 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3631

Melike Güngör, Kevser Sağlamkol, Zeynep Yağmur Baydemir, Ali Kiliç

{"title":"Production of gelatin fibrous mats using different nanofiber production methods for medical applications and comparison of their properties.","authors":"Melike Güngör, Kevser Sağlamkol, Zeynep Yağmur Baydemir, Ali Kiliç","doi":"10.55730/1300-0527.3631","DOIUrl":"10.55730/1300-0527.3631","url":null,"abstract":"In the literature, there are studies on medical applications using different nanofiber production methods with natural polymers. However, each system has different fiber-forming capabilities. For this reason, in this study, we investigated the production of nanofibers from a biodegradable natural polymer, gelatin, using four separate nanofiber production methods, namely electrospinning (ES), electroblowing (EB), solution blowing (SB), and centrifugal spinning (CS). Our aim was to determine the most suitable fibrous web structure for medical applications and contribute to science in this respect. It was observed that the thinnest fibers (386 nm) and the heaviest mats (15.975 g m-2) were produced by the SB method as a result of using 10 wt.% gelatin solution with a total of 10 mL. With the ES and EB methods, tighter fabric structures were obtained than with the others due to the presence of electric fields. In the CS method, more and bead-free fibers were produced due to the increase in viscosity with a 12.5 wt.% gelatin solution. Moreover, with the concentration of 12.5 wt.%, the fiber diameters of SB and CS samples increased about 2-fold.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1508-1517"},"PeriodicalIF":1.4,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable graphitic carbon from biomass to be suitable for technological devices. 从生物质中提取适用于技术设备的可持续石墨碳。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-16 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3621

Gökçen Akgül

引用次数: 0

Optimum pyrolysis conditions to prepare the most crystalline boron carbide powder from boric acid-mannitol complex ester. 从硼酸-甘露醇复合酯中制备结晶度最高的碳化硼粉末的最佳热解条件。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3620

Abdullah Devrim Pekdemir, Müşerref Önal, Yüksel Sarikaya

{"title":"Optimum pyrolysis conditions to prepare the most crystalline boron carbide powder from boric acid-mannitol complex ester.","authors":"Abdullah Devrim Pekdemir, Müşerref Önal, Yüksel Sarikaya","doi":"10.55730/1300-0527.3620","DOIUrl":"10.55730/1300-0527.3620","url":null,"abstract":"A weak acidic complex ester (CE) in solid form was prepared by a condensation reaction between very weak boric acid (BA: H3BO3) and (D)-mannitol (MA: C6H14O6) by the molar ratio of BA/MA = 2. A boron carbide (B4C) precursor was obtained from heating of the CE at 400 °C for 4 h. The precursor was pyrolyzed under argon flow in the interval of 1300-1550 °C for 4 h and at 1400 °C for 1-4 h, respectively. The materials were examined using several techniques such as X-ray diffraction analysis, thermal analysis, scanning electron microscopy, particle size distribution, and nitrogen adsorption/desorption. The optimum pyrolysis temperature and duration were 1400 °C and 4 h, respectively. The most crystalline B4C particles were distributed between 1 and 100 μm with a mean particle size of 20 μm. The specific surface area and specific pore volume were 13.5 m2 g-1 and 0.09 cm3 g-1, respectively. The size of the pores was between 2 and 36 nm with a mean size of 14 nm.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1370-1379"},"PeriodicalIF":1.4,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bromination and conversion of tetrahydro-1H-indene to bisoxirane with a new approach: synthesis, structural characterization by spectroscopic and theoretical methods, and biological analysis supported by DFT and docking. 用一种新方法将四氢-1H-茚溴化并转化为双环氧乙烷：合成、通过光谱和理论方法确定结构特征，以及在 DFT 和对接支持下进行生物学分析。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-11 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3628

Raşit Fikret Yilmaz, Sultan Erkan, Salih Ökten, Ahmet Tutar, Ertan Şahin

{"title":"Bromination and conversion of tetrahydro-1H-indene to bisoxirane with a new approach: synthesis, structural characterization by spectroscopic and theoretical methods, and biological analysis supported by DFT and docking.","authors":"Raşit Fikret Yilmaz, Sultan Erkan, Salih Ökten, Ahmet Tutar, Ertan Şahin","doi":"10.55730/1300-0527.3628","DOIUrl":"10.55730/1300-0527.3628","url":null,"abstract":"In this study, a new method for synthesizing diepoxides is proposed. Tetrahydroindene 1 was brominated with NBS in the presence of LiClO4 and acetic acid, resulting in the formation of dibromodiacetate derivatives 2 and 3. Treatment of compounds 2 and 3 with NaOH in methanol produced a mixture of diepoxides 4 and 5. Additionally, direct bromination of tetrahydro-1H-indene yielded tetrabromo octahydroindene isomers 6 and 7. The structures of the compounds were characterized using spectroscopic techniques such as 1H NMR, 13C NMR, APT, COSY, and XRD. The new method provides an easy and selective route to access epoxides for the synthesis of various chemicals. This study also highlights the selective formation of endo-exo and exo-exo orientations of the obtained diepoxides, distinguishing it from previous studies. The stability and properties of the stereoisomers were investigated using computational methods, revealing the most stable configurations. Reactive sites in the molecules were identified using contour diagrams and molecular electrostatic potential maps. The anticancer properties of the compounds were evaluated in silico, comparing them to 5-fluorouracil (5-FU) against several cancer cell lines. The compounds exhibited the most effective anticancer activity against MCF-7 cells, with the order of anticancer activities generally determined as 2 > 7 > 3 > 6 > 5 > 4 > 5-FU.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1459-1478"},"PeriodicalIF":1.4,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of metal-carbenoid reactions of β-2-five-membered heteroaryl substituted α,β-unsaturated ketones. β-2-五元杂芳基取代的 α、β-不饱和酮的金属-类羰基反应比较。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-11 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3625

Kumsal Eroğlu, Olcay Anaç, Füsun Şeyma Kişkan

引用次数: 0

Synthesis and singlet oxygen generation of boron-2-(4,5-dibromo-1H-imidazole-2-yl)-3,5-dipyrazolopyridine complex for antimicrobial photodynamic therapy. 用于抗菌光动力疗法的硼-2-(4,5-二溴-1H-咪唑-2-基)-3,5-二吡唑吡啶复合物的合成和单线态氧生成。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-11 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3627

Zeynep Ekmekçi, Seda Karaoğlu

{"title":"Synthesis and singlet oxygen generation of boron-2-(4,5-dibromo-1H-imidazole-2-yl)-3,5-dipyrazolopyridine complex for antimicrobial photodynamic therapy.","authors":"Zeynep Ekmekçi, Seda Karaoğlu","doi":"10.55730/1300-0527.3627","DOIUrl":"10.55730/1300-0527.3627","url":null,"abstract":"In this study, the pyridine side of a boron 2-(2'-pyridyl) imidazole (BOPIM) core, which has very few derivatives synthesized in the literature and can show fluorescence properties in solid form, was derivatized with 1-methylpyrazole, predicted to have activity against fungi or bacteria according to the literature. Additionally, its imidazole side was brominated to increase the efficiency of singlet oxygen production by increasing the intersystem crossing. The photophysical properties of the new synthesized BOPIM derivative were investigated in general organic solvents with different polarities. While the wavelength of the maximum absorbance was determined as 406 nm in CH2Cl2 and THF, the wavelength of the highest emission was measured at 497 nm in CH3CN solvent. The largest Stokes shift was determined as 104 nm in CH3CN. This value was considerably higher than those of many photosensitizers. The singlet oxygen generation potential of the BOPIM derivative was revealed using a 440-nm LED lamp in the presence of singlet oxygen scavenger 1,3-diphenylisobenzofuran (DPBF). Additionally, it was demonstrated that the BOPIM derivative had no toxic effects by measurements made in the dark.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1452-1458"},"PeriodicalIF":1.4,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intercalation of pyrazolone-based oxalamide metal complexes into Na-montmorillonite for catalytic liquid-phase oxidation of phenol using H₂O₂. 在 Na-montmorillonite 中掺入吡唑啉酮草酰胺金属复合物，利用 H2O2 对苯酚进行催化液相氧化。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-10 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3630

Serhat Uzan, Eyüp Başaran

{"title":"Intercalation of pyrazolone-based oxalamide metal complexes into Na-montmorillonite for catalytic liquid-phase oxidation of phenol using H2O2.","authors":"Serhat Uzan, Eyüp Başaran","doi":"10.55730/1300-0527.3630","DOIUrl":"10.55730/1300-0527.3630","url":null,"abstract":"The intercalation of pyrazolone-based oxalamide metal complexes into Na-montmorillonite (Na-MMT) for catalytic liquid-phase oxidation of phenol using H2O2 was undertaken by a flexible ligand method using metal ions including Mn(II), Zn(II), and Sn(II). First, the metal ions were exchanged with the sodium ions of Na-MMT, and then these metal ions were complexed with a new pyrazolone-based oxalamide ligand. The intercalated metal complexes were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, elemental analysis, and thermogravimetric analysis. Phenol was successfully oxidized by heterogeneous catalysts based on Mn(II), Zn(II), and Sn(II) pyrazolone-based oxalamide complexes intercalated into Na-MMT. These heterogeneous catalysts catalyze the liquid-phase oxidation of phenol using H2O2 to catechol as the major product and hydroquinone and benzoquinone as the minor products. The Mn(II) and Zn(II) complexes intercalated into Na-MMT showed better activity than the Sn(II) complex intercalated into Na-MMT and the reaction without the catalyst. It has been shown that some metal ion complexes intercalated into Na-MMT are active catalysts for liquid-phase oxidation of phenol with hydrogen peroxide.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1497-1507"},"PeriodicalIF":1.4,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photophysical, thermal, and DFT studies on a tetraaryl-azadipyrromethene ligand and its zinc(II) complex. 四芳基偶氮二吡咯烷乙烯配体及其锌（II）配合物的光物理、热学和 DFT 研究。

IF 1.4 4区化学

Turkish Journal of Chemistry Pub Date : 2023-10-10 eCollection Date: 2023-01-01 DOI: 10.55730/1300-0527.3626

Gökhan Sevinç

{"title":"Photophysical, thermal, and DFT studies on a tetraaryl-azadipyrromethene ligand and its zinc(II) complex.","authors":"Gökhan Sevinç","doi":"10.55730/1300-0527.3626","DOIUrl":"10.55730/1300-0527.3626","url":null,"abstract":"An azadipyrromethene ligand (H1) and homoleptic zinc(II) (H1-Zn) complex were synthesized. The resulting structures were elucidated by NMR, FTIR, and HRMS techniques. The photophysical properties and effects of complexing the zinc(II) atom to azadipyrromethene ligands in solution were studied by means of UV-Vis absorption and fluorescence spectroscopy. Experimental findings were elucidated using density functional theory computations and interfragment charge transfer (IFCT) and electron-hole analyses. The fluorescence features were found to be negligible. The ligand molecule decayed at a rate of 3% while the complex decayed at 2% upon photoirradiation based on photostability experiments. The singlet oxygen quantum yields of the ligand and complex were calculated as 0.127 and 0.233, respectively, signifying low photodynamic activity. The charge transfer transitions were determined between reciprocal ligands responsible for the red shift of the main absorption band by IFCT and electron-hole analysis. Compounds in an inert N2 atmosphere demonstrated high thermal stability. Although the thermogravimetric analysis (TGA) and derivative thermogravimetry curves of the complexes were similar, zinc(II) coordination and homoleptic complex formation reduced the degradation temperatures. These findings suggest that azadipyrromethene and the Zn(II) class of chromophores have beneficial features for use in the development of novel photo- and thermostable materials that combine charge transfer with low energy in the visible and near infrared regions.","PeriodicalId":23367,"journal":{"name":"Turkish Journal of Chemistry","volume":"47 6","pages":"1438-1451"},"PeriodicalIF":1.4,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0