Comparatively sonophotochemical and photochemical studies of phthalocyanines with cationic substituents on nonperipheral positions

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Turkish Journal of Chemistry Pub Date : 2023-10-31 DOI:10.55730/1300-0527.3602

MUKADDES ÖZÇEŞMECİ, CEREN CAN KARANLIK, ALİ ERDOĞMUŞ, ESİN HAMURYUDAN

引用次数: 0

Abstract

The term sonophotodynamic therapy (SPDT) refers to a combination of sonodynamic therapy (SDT) and photodynamic therapy (PDT), in which the efficacy of the treatment is boosted by utilizing the proper amount of a sensitizer that is responsive to both light and ultrasound. Although it has been proven in photophysicochemical studies that SPDT enhances singlet oxygen production, related studies in the literature are very limited. Considering this situation, this study aims to investigate the efficacy of synthesized phthalocyanines in terms of PDT and SPDT. The singlet oxygen quantum values calculated as 0.13 for 5, 0.44 for 6, and 0.61 for 7 in photochemical (PDT) application increased to 0.18, 0.86, and 0.92, respectively, with sonophotochemical (SPDT) application. According to the results, singlet oxygen production was more efficient with SPDT. This work will add to the body of knowledge on employing the SPDT approach to increase singlet oxygen generation

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非外周位置带阳离子取代基酞菁的声光化学和光化学比较研究

术语声光动力疗法(SPDT)是指声动力疗法(SDT)和光动力疗法(PDT)的结合，其中通过利用适量对光和超声均有反应的敏化剂来提高治疗效果。虽然在光物理化学研究中已经证明SPDT可以促进单线态氧的产生，但相关的文献研究非常有限。鉴于此，本研究旨在考察合成的酞菁在PDT和SPDT方面的功效。单线态氧量子值在光化学(PDT)应用中分别为0.13(5)、0.44(6)和0.61(7)，在声光化学(SPDT)应用中分别增加到0.18、0.86和0.92。结果表明，SPDT的单线态产氧效率更高。这项工作将增加使用SPDT方法增加单线态氧生成的知识体系

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Turkish Journal of Chemistry 化学-工程：化工

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

3 months

期刊介绍： The Turkish Journal of Chemistry is a bimonthly multidisciplinary journal published by the Scientific and Technological Research Council of Turkey (TÜBİTAK). The journal is dedicated to dissemination of knowledge in all disciplines of chemistry (organic, inorganic, physical, polymeric, technical, theoretical and analytical chemistry) as well as research at the interface with other sciences especially in chemical engineering where molecular aspects are key to the findings. The journal accepts English-language original manuscripts and contribution is open to researchers of all nationalities. The journal publishes refereed original papers, reviews, letters to editor and issues devoted to special fields. All manuscripts are peer-reviewed and electronic processing ensures accurate reproduction of text and data, plus publication times as short as possible.