Tobacco Induced Diseases最新文献

{"title":"The effect of heated tobacco products on metabolic syndrome: A cohort study.","authors":"Yongho Jee, Sang Yop Shin, Mikyung Ryu, Jonathan M Samet","doi":"10.18332/tid/194490","DOIUrl":"10.18332/tid/194490","url":null,"abstract":"<p><strong>Introduction: </strong>Evidence concerning the health effects of using heated tobacco products is needed. The aim of the present study is to investigate the effects of conventional cigarettes (CCs), electronic vaping cigarettes (EVCs), and heated tobacco products (HTPs) on the development of metabolic syndrome.</p><p><strong>Methods: </strong>We conducted a cohort study in South Korea using data from the Korea Medical Institute. The study included 183870 people who visited the Korea Medical Institute, responded to a smoking status questionnaire in 2019, and were followed up in 2020 - ever and current use of CCs, EVCs, and HTPs. We defined the main outcome as incident metabolic syndrome among participants with at least two health checkups separated by a follow-up period of at least a year.</p><p><strong>Results: </strong>The association of using HTPs with risk for metabolic syndrome was estimated after controlling for age, sex, exercise, drinking history, and smoking regular cigarettes and using EVCs, with the Cox proportional hazards model. The risk of incident metabolic syndrome was increased by 68% (HR=1.68; 95% CI: 1.25-2.26) for current HTP users compared to never users. Among HTP users who did not currently smoke conventional cigarettes, the risk was doubled (HR=2.17; 95% CI: 1.31-3.62) when their smoking duration was ≥3 years. The risk of metabolic syndrome increased by 33% (HR=1.33; CI: 1.18-1.49) among HTP users who used them more than 16 times a day. The use of HTP was found to increase the risk of developing metabolic syndrome, with a particularly elevated risk observed among those who used HTPs for more than three years. The risk was higher than that observed in conventional cigarette users.</p><p><strong>Conclusions: </strong>Our findings indicate that HTP use poses comparable risks in relation to metabolic syndrome development.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Association of cigarette smoking with cardiometabolic risk factors: A cross-sectional study.","authors":"Samar Sultan, Fouzy Lesloom","doi":"10.18332/tid/196812","DOIUrl":"https://doi.org/10.18332/tid/196812","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.18332/tid/191246.].</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-period-cohort analysis of smoking prevalence trends among career military personnel in South Korea.","authors":"Sunju Jung, Heewon Kang, Sung-Il Cho","doi":"10.18332/tid/196477","DOIUrl":"10.18332/tid/196477","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated smoking trends among career military personnel in South Korea. After a tobacco tax increase in 2015, the tobacco control program for career military personnel expanded significantly. This study explores long-term smoking trends among career military personnel through age-period-cohort (APC) analysis within the context of targeted tobacco control policies.</p><p><strong>Methods: </strong>This secondary data analysis utilized data from 12052 individuals aged 19--54 years, identified as career military personnel in the Korea Community Health Survey (KCHS) from 2008 to 2022. APC analysis with the intrinsic estimator (IE) method was conducted to address multicollinearity and accurately assess the contributions of age, period, and birth cohort to smoking prevalence.</p><p><strong>Results: </strong>Smoking prevalence significantly decreased among career military personnel, from 46.2% in 2008 to 34.1% in 2022. The highest prevalence of smoking was initially observed in the age group of 22-24 years. Although overall prevalence declined, a slight increase was observed in the age group of mid-30s to early 40s, suggesting that smoking behavior varied across age groups. A significant decrease occurred between 2014 and 2016, with individuals born in the 1970s exhibiting the highest smoking prevalence, and those born after 1980 demonstrating a notably lower smoking prevalence.</p><p><strong>Conclusions: </strong>Although smoking prevalence has declined, the distinct age, period, and cohort characteristics of career military personnel necessitate tailored tobacco control policies that consider the various aspects of military life.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total serum bilirubin levels as mediators of anti-atherosclerosis mechanisms with consideration of smoking status.","authors":"Shigemasa Tani, Kazuhiro Imatake, Yasuyuki Suzuki, Tsukasa Yagi, Atsuhiko Takahashi","doi":"10.18332/tid/195378","DOIUrl":"https://doi.org/10.18332/tid/195378","url":null,"abstract":"<p><strong>Introduction: </strong>Cigarette smoking is a significant risk factor for atherosclerotic cardiovascular diseases (ASCVDs). Mildly elevated total serum bilirubin (TSB) levels can exert anti-atherosclerotic effects and may regulate inflammation. We explore the relationship between TSB levels, smoking, and inflammation.</p><p><strong>Methods: </strong>This cross-sectional study evaluated health screening participants with no history of ASCVD between 1 April 2019 and 31 March 2020. TSB was compared between non-smokers and smokers using the Kruskal-Wallis test, and the influencing factors of TSB levels were identified using multivariable logistic regression with TSB levels above the 75th percentile set as the dependent variable. Mediation analysis was performed to determine whether TSB levels mediated the association between smoking and inflammation.</p><p><strong>Results: </strong>A total of 8337 participants (mean age: 46.6 ± 13.0 years; 58.9% men) were included. TSB levels were significantly lower in smokers (n=1353) than in non-smokers (n=6984) [median (IQR): 0.72 (0.56-0.92) vs 0.76 (0.60-0.97) mg/dL, p<0.0001]. Multivariable logistic regression analysis demonstrated that smoking was an independent determinant of lower TSB levels (adjusted odds ratio, AOR=0.81; 95% CI: 0.70-0.93, p=0.003). Leukocyte counts and C-reactive protein levels significantly decreased as TSB levels increased (p<0.0001). Moreover, the relationship between the duration of smoking cessation and TSB levels showed a positive correlation. Mediation analysis indicated that cigarette smoking had significant indirect effects on higher leukocyte counts and higher CRP levels (coefficient=0.014; 95% CI: 0.008-0.021; and coefficient=0.002; 95% CI: 0.001-0.003, respectively].</p><p><strong>Conclusions: </strong>Lower TSB levels related to a smoking habit may be associated with higher inflammation, thereby increasing the ASCVD risk. TSB may regulate inflammation and exert antioxidant effects. Furthermore, smoking cessation may lead to higher TSB levels and lower inflammation.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the serum cotinine and trabecular bone score in the adult population: A cross-sectional study.","authors":"Shifu Bao, Weibu Jimu, Nai Mu, Fang Yan, Shuxing Xing, Zheng Zhou","doi":"10.18332/tid/194680","DOIUrl":"10.18332/tid/194680","url":null,"abstract":"<p><strong>Introduction: </strong>Trabecular bone score (TBS) is gaining attention as a novel approach for evaluating bone quality, as it provides insights into skeletal microarchitecture. We aimed to investigate the possible relationship between serum cotinine and TBS in the US population.</p><p><strong>Methods: </strong>This cross-sectional study utilized data from the 2005-2008 National Health and Nutrition Examination Survey (NHANES). A total of 6961 adults aged ≥20 years with complete data on TBS and serum cotinine were included. Serum cotinine levels were measured using isotope-dilution high-performance liquid chromatography coupled with tandem mass spectrometry. TBS was derived from lumbar spine DXA images using the Med-Imap SA TBS Calculator. Weighted multivariable linear regression analyses were conducted, adjusting for age, sex, race, BMI, poverty income ratio (PIR), total spine bone mineral density (TSBMD), smoking status, C-reactive protein (CRP), total protein, blood urea nitrogen, serum creatinine, serum uric acid, serum calcium, alkaline phosphatase, and serum phosphorus. Subgroup analyses were stratified by sex, race, BMI, and PIR.</p><p><strong>Results: </strong>A total of 6961 individuals were included in the analysis, with a mean (± SE) age of 45.20 ± 0.39 years, comprising 49.21% males and 50.79% females. The serum level of cotinine was negatively associated with TBS in the fully adjusted model. Specifically, for each unit increase in the log2-cotinine score, there was a corresponding 0.01 unit decrease in TBS (β= -0.01; 95% CI: -0.02 - -0.01, p=0.002). Participants in the highest tertile of serum cotinine had a significantly lower TBS compared to those in the lowest tertile (β= -0.01; 95% CI: -0.02 - -0.01, p=0.002). Subgroup analysis revealed a significant negative association between serum cotinine and TBS in females (β= -0.021; 95% CI: -0.03 - -0.01), but not in males. No significant associations were found when stratified by race, BMI, and PIR.</p><p><strong>Conclusions: </strong>Serum cotinine was negatively associated with TBS in US adults. Further large-scale prospective studies are still needed to explore the associative relationship of cotinine in TBS.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions for smoking cessation: An overview of Cochrane reviews.","authors":"Chun-Li Lu, Jia-Xuan Li, Qian-Yun Wang, Rui-Ting Wang, Xing-Ru Pan, Xiao-Ying Chen, Chao-Jie Wang, Rui-Lin Chen, Si-Hong Yang, Zhi-Hui Zhao, Jing-Jing Jiang, Xue-Han Liu, Jian-Hua Wang, Xue Xue, Li-Rong Liang, Nicola Robinson, Jian-Ping Liu","doi":"10.18332/tid/195302","DOIUrl":"10.18332/tid/195302","url":null,"abstract":"<p><strong>Introduction: </strong>Evidence of different smoking cessation interventions varies and has been assessed in many Cochrane reviews. We conducted an overview of these Cochrane reviews to summarize the effects of current interventions for smoking cessation.</p><p><strong>Methods: </strong>Nine databases were searched from their inception to October 2024, with no restrictions on language. Two authors independently extracted data from the same studies simultaneously, double checking after extraction. A second round of examination was conducted on all the extracted contents by another author. We employed a measurement tool to assess systematic reviews (AMSTAR-2) to evaluate the methodological rigor of the included systematic reviews (SRs), synthesized the GRADE results as reported, and conducted a narrative synthesis. The research protocol was registered on PROSPERO (CRD42023388884).</p><p><strong>Results: </strong>Seventy-one Cochrane reviews involving 3022 trials were included in this comprehensive analysis. The two predominant smoking cessation interventions were pharmacotherapy (24 SRs) and non-pharmacological therapy (31SRs). Overall, the methodological quality of all the reviews was good. Compared with placebo, the point effect size for each Cochrane review on relative risk (RR) regarding pharmacotherapies for prolonged abstinence rate ranged from 1.11 to 3.34, demonstrating high- or moderate-certainty evidence; whereas for non-pharmacological therapies, it varied from 0.79 to 25.38, but substantial heterogeneity was observed in most meta-analysis (I2>50%). Four studies investigating pharmacotherapies as interventions, adverse events were reported but no significant differences in outcomes were observed.</p><p><strong>Conclusions: </strong>Pharmacotherapy demonstrated some efficacy in promoting prolonged abstinence rate, while the effectiveness of different non-pharmacological interventions for smoking cessation varied widely, highlighting the need for further research on the integration of pharmacotherapy and non-pharmacological therapies.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reasons for cigarette and tobacco product use, dual use, and poly use among university students.","authors":"Mark J M Sullman, Maria E Gras, Jiawei D Hughes, Ioulia Papageorgi, Fran Calvo, Sílvia Font-Mayolas","doi":"10.18332/tid/195379","DOIUrl":"10.18332/tid/195379","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco use remains a significant public health issue worldwide, causing over 7 million deaths annually. Polytobacco use has become a common phenomenon. This study aims to analyze reasons for cigarette and tobacco product use, dual use and poly use among university students by sex, in China and Cyprus, selected owing to their still high consumption rates.</p><p><strong>Methods: </strong>An online survey was conducted among 589 university students (55% women) with a mean age of 24.2 years from Guangzhou, China, and the Republic of Cyprus. Participants reported their use of cigarettes, e-cigarettes, and waterpipes, as well as their reasons for using these products. Statistical analyses included chi-squared tests, and effect sizes were computed using the phi (φ) coefficient.</p><p><strong>Results: </strong>The Chinese participants gave as reasons for using cigarettes: 'because of the taste', 'because it looks cool', 'to get high' and 'because friends and family use them'. These were less frequently given by the Cypriots who opted more for 'to relax and relieve tension'. Compared to the Cypriot participants, the more frequent reasons given for consuming e-cigarettes and waterpipes among Chinese students were: 'due to boredom', 'because it looks cool', 'to get high', 'because I am hooked', 'because friends or family members use them', 'because they are less harmful than regular cigarettes' and 'because friends of family members allow their use more'. Dual or poly users felt more addicted than those who practiced single use. Among e-cigarette users, dual users and poly users valued the taste of the product more than single users. In general, men found more reasons for tobacco use than women did.</p><p><strong>Conclusions: </strong>This study shows substantial differences in the motivation for using these products according to the product type, number of tobacco/nicotine products used, country, and sex. Understanding the reasons for tobacco use can inform targeted interventions aimed at reducing tobacco consumption among young adults.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11583615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective evaluation of parental smoking and the risk of Type 1 diabetes in children.","authors":"Ipek Cicekli, Raika Durusoy","doi":"10.18332/tid/195228","DOIUrl":"10.18332/tid/195228","url":null,"abstract":"<p><strong>Introduction: </strong>The association between secondhand smoking (SHS) and the risk of Type 1 diabetes mellitus (DM) has garnered increasing interest. The aim of this study is to examine whether exposure to SHS is associated with an increased likelihood of Type 1 DM.</p><p><strong>Methods: </strong>This study was designed as a case-control study. Children aged 4-14 years diagnosed with Type 1 DM who were followed in the Endocrine and Metabolic Diseases Outpatient Clinic were included as cases, and healthy children (without any chronic disease) in the same age range were included as the controls. A total of 248 children were included in the study, with two research arms. The structured questionnaire was applied face-to-face. Adjusted odds ratios (AOR) and 95% confidence intervals (CIs) of other risk factors were evaluated by multivariable regression analysis.</p><p><strong>Results: </strong>No difference was found in the number of cigarettes mothers smoked daily and the duration of the smoking period during pregnancy and lactation, between the two groups. Among the cases, the daily number of cigarettes smoked by parents at home was 3.28 ± 4.90, higher than in the controls (p=0.039). Comparing the controls, children with Type 1 DM were more likely to be exposed to SHS at home by 1.08 (95% CI: 1.004-1.15, p=0.039) times in cases.</p><p><strong>Conclusions: </strong>Children with Type 1 DM had higher odds of being exposed to SHS at home. These results suggest substantial health gains could be made by extending effective public health interventions to reduce exposure to SHS and prevent Type 1 DM in children.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of tobacco smoking and alcohol consumption on the treatment efficacy among psoriasis patients: A study protocol.","authors":"Fanlingzi Shen, Yuning Ding, Ruiping Wang","doi":"10.18332/tid/195380","DOIUrl":"10.18332/tid/195380","url":null,"abstract":"<p><p>Psoriasis is a common skin disease. With an in-depth understanding of psoriasis, small-molecule drugs and biologics are developed and used in clinical practice, but some patients still cannot achieve a satisfactory therapeutic effect. Tobacco smoking and alcohol drinking are proven to be factors affecting psoriasis. Still, evidence of the impact of tobacco smoking and alcohol consumption on the efficacy of psoriasis treatment is limited. This study aims to understand the prevalence of tobacco smoking and alcohol drinking among patients with psoriasis in Shanghai and to examine the association between tobacco smoking as well as alcohol drinking and the therapeutic effect in patients with psoriasis. We conducted a longitudinal observational study and recruited at least 500 psoriasis patients at Shanghai Skin Disease Hospital. In this study, patients with clinically diagnosed psoriasis vulgaris, aged ≥18 years, both males and females, with informed consent were recruited. However, patients with pregnancy, serious underlying disease conditions, communication barriers, and violation of medication regulations were excluded. Patients with psoriasis in this study receive a physical examination and case record form interview. The primary outcome indicator is the proportion of patients with PASI₇₅ achievement at Week 8. In this study, we use SAS 9.2 software to analyze the data. This study has been reviewed and approved by the Institutional Ethics Review Committee of Shanghai Skin Disease Hospital in 2021 (NO. 2021-44). It has been registered in the Chinese Clinical Trial Registry (ChiCTR2200066403). Patient recruitment began in January 2021 and is proposed to be finished in December 2024. The findings in this study will provide evidence of how tobacco smoking and alcohol drinking impact the treatment efficacy among patients with psoriasis. Therefore, the implementation of tobacco control and alcohol abstinence benefit the improvement of treatment responses.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of the use of e-cigarettes, combustible cigarettes or dual use with hypertension and mortality in hypertensive individuals: Insights from NHANES 2015-2018.","authors":"Yi Lu, Hao Jiang, Yin Ren, Meixiang Wang, Aili Yuan, Jing Wu, Zhongbao Ruan, Xiangwei Ding","doi":"10.18332/tid/195397","DOIUrl":"10.18332/tid/195397","url":null,"abstract":"<p><strong>Introduction: </strong>Combustible cigarettes have been shown to increase hypertension risk. Nevertheless, data on the association between electronic cigarettes (e-cigarettes), as well as dual use of e-cigarettes and combustible cigarettes, and hypertension, are limited.</p><p><strong>Methods: </strong>This study aims to examine the association of the use of e-cigarettes, combustible cigarettes or dual use with hypertension. Data from the 2015-2018 National Health and Nutrition Examination Survey were used. Weighted logistic regression models were employed to determine the relationship between cigarette use and hypertension. Weighted Cox proportional hazard regression models were developed to evaluate the association between electronic/combustible cigarettes or dual use and mortality in hypertensive individuals.</p><p><strong>Results: </strong>A total of 7696 participants (median age 47 years; 51.76% females) were included. In the adjusted model, the groups of e-cigarette use, combustible cigarette use, and dual use were found to be significantly associated with the risk of hypertension with AOR and 95% CI of 1.56 (1.01-2.42), 1.29 (1.01-1.64) and 1.83 (1.03-3.27) respectively. Significant trends of the relationship between cigarette use and hypertension were observed. The median follow-up for mortality was 38 months. Current e-cigarette use showed a positive correlation with all-cause death and cardiovascular death compared to never e-cigarette use with HR and 95% CI of 1.30 (1.01-1.66) and 1.30 (1.01-1.67), respectively. The trend of association of e-cigarette use with mortality was significant.</p><p><strong>Conclusions: </strong>This study shows that electronic/combustible cigarette use or dual use increased risk of hypertension. E-cigarettes were associated with a higher risk of all-cause mortality and cardiovascular mortality. Notably, the increased risk of mortality among e-cigarette users may be due to underlying, pre-existing comorbidities related to prior combustible cigarette use. Findings from the study provide evidence of the benefits of e-cigarette use control, especially among individuals with hypertension.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"22 ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}