Global, regional, and national burden of tobacco-related neurological disorders from 1990 to 2021: Trends and future projections.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tobacco Induced Diseases Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI:10.18332/tid/201966

Chenyang Zhang, Zhihan An, Jixuan Jiang, Jingyi Ge, Wanqiong Huang, Jialin Pei, Yiyao Liu, Jiayu Yao, Zirui Guo, Xuanxi Liu, Yanhui Cui

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引用次数: 0

Abstract

Introduction: Tobacco use is as a major public health concern around the world, adversely impacting quality of life. Our study aims to analyze the trends in the burden of tobacco-related neurological disorders (ND) at global, regional, and national levels from 1990 to 2021, as well as potential future trends.

Methods: We performed a secondary dataset analysis for the assessment of mortality and disability-adjusted life years (DALYs) using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, to explore the burden of tobacco-related ND. We also analyzed the associations between the burden of ND and factors such as age, gender, and the Sociodemographic Index (SDI).

Results: In 2021, the age-standardized mortality rate (ASMR) and age-standardized DALYs rate (ASDR) for neurological disorders were 0.50 per 100000 persons (95% UI: -0.15-1.98) and 11.25 per 100000 persons (95% UI: 1.36-34.36), respectively. Alzheimer's disease and other dementias (ADOD) had a particularly significant impact on the burden of ND. However, the ASDR for Parkinson's disease was -8.38 per 100000 persons (95% UI: -10.72 - -6.20). The burden of disease was greater in men and older people, with substantial regional variation. While aging and population growth might contribute to the increase in DALYs for tobacco-related ND, epidemiological changes have the potential to reduce the burden. From 2022 to 2050, the BAPC model predicted a decline in the age-standardized rate (ASR) of DALYs and mortality for tobacco-related ND, globally.

Conclusions: Tobacco use increased the burden of ND such as ADOD and multiple sclerosis (MS), while reducing the burden of Parkinson's disease (PD). The burden of disease was disproportionately higher among older individuals and males, with significant disparities across nations and regions. Over the past 32 years, the burden of these diseases has gradually decreased, and this trend is expected to continue from 2022 to 2050.

查看原文本刊更多论文

1990 至 2021 年全球、地区和国家与烟草相关的神经系统疾病负担：趋势和未来预测。

烟草使用是世界各地的一个主要公共卫生问题，对生活质量产生不利影响。本研究旨在分析1990年至2021年全球、区域和国家各级烟草相关神经系统疾病（ND）负担的趋势，以及潜在的未来趋势。方法：我们使用来自2021年全球疾病、伤害和风险因素负担研究（GBD）的数据，对死亡率和残疾调整生命年（DALYs）进行了二次数据集分析，以探讨烟草相关ND的负担。我们还分析了ND负担与年龄、性别和社会人口指数（SDI）等因素之间的关系。结果：2021年，神经系统疾病的年龄标准化死亡率（ASMR）和年龄标准化DALYs率（ASDR）分别为0.50 / 10万人（95% UI: -0.15-1.98）和11.25 / 10万人（95% UI: 1.36-34.36）。阿尔茨海默病和其他痴呆（ADOD）对ND负担的影响尤为显著。然而，帕金森病的ASDR为-8.38 / 100000人（95% UI: -10.72 - -6.20）。男性和老年人的疾病负担更大，地区差异很大。虽然老龄化和人口增长可能导致与烟草有关的ND的DALYs增加，但流行病学变化有可能减轻负担。从2022年到2050年，BAPC模型预测全球范围内与烟草相关ND的DALYs年龄标准化率（ASR）和死亡率将下降。结论：烟草使用增加了adhd和多发性硬化症（MS）等ND的负担，而减轻了帕金森病（PD）的负担。老年人和男性的疾病负担高得不成比例，各国和各区域之间存在显著差异。在过去32年中，这些疾病的负担逐渐减少，预计这一趋势将从2022年持续到2050年。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tobacco Induced Diseases SUBSTANCE ABUSE-PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

CiteScore

5.30

自引率

5.40%

发文量

审稿时长

12 weeks

期刊介绍： Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community. The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.