Tobacco-related lung cancer burden in the Western Pacific Region from 1990 to 2021: An age-period-cohort analysis from the Global Burden of Disease Study.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tobacco Induced Diseases Pub Date : 2025-03-13 eCollection Date: 2025-01-01 DOI:10.18332/tid/201970

Rui Wang, Zhiqiang Zhang, Xiaoxi Shan, Jiayang Dong, Xinyue Yang, Jing Zhang, Jie Cao

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引用次数: 0

Abstract

Introduction: Lung cancer is a significant health issue in the Western Pacific region, where tobacco use is highly prevalent. This study examines the trends in tobacco-related lung cancer burden from 1990 to 2021, offering insights into the evolution of this critical public health challenge.

Methods: This study uses data from the Global Burden of Disease (GBD) 2021 study to analyze lung cancer rates. It employs an age-period-cohort analysis to explore patterns in mortality and disability-adjusted life-years (DALYs) attributed to tobacco-related lung cancer. The study also uses joinpoint regression analysis to pinpoint changes over different periods.

Results: Our analyses revealed a substantial rise in both the number of deaths and DALYs due to tobacco-related lung cancer in the Western Pacific region from 1990 to 2021. Total deaths increased by 163.42% to 644.5 thousand (95% UI: 517.9-793.8) in 2021, which is 2.6 times the global growth rate of 63.25%. While global ASMR decreased by 25.46%, the Western Pacific Region showed minimal change with a slight increase (AAPC=0.08). SDI analysis revealed an inverse relationship with burden - for example, Singapore's ASMR decreased from 20.4 to 7.0 per 100000 population (high SDI) while China's increased from 23.8 to 25.8 (middle SDI). Age-period-cohort analysis showed the net drift of lung cancer mortality was -0.16% per year. The fastest increase in ASMR occurred between 1998-2004 (APC=1.53%), followed by the steepest decline during 2004-2007 (APC= -1.49%).

Conclusions: The Western Pacific region continues to face a high burden of tobacco-related lung cancer.

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来源期刊

Tobacco Induced Diseases SUBSTANCE ABUSE-PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

CiteScore

5.30

自引率

5.40%

发文量

审稿时长

12 weeks

期刊介绍： Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community. The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.