The Scientific World Journal最新文献

{"title":"Navigating Personal, Social, and Environmental Obstacles to Healthy Lifestyle in Jordanian Adolescents.","authors":"Rula A Amr, Ahmed M Al-Smadi, Nanda Alqutob, Rand T Akasheh","doi":"10.1155/tswj/8889672","DOIUrl":"10.1155/tswj/8889672","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to investigate barriers hindering healthy eating and physical activity among Jordanian adolescents. <b>Methods:</b> A random sample of 1040 adolescents (596 males and 444 females) aged 11-17 from various Jordanian schools participated. A nutritionist-administered questionnaire assessed barriers. <b>Results:</b> The study unveiled diverse personal, social, and environmental barriers to healthy lifestyles. Notably, inadequate knowledge of nutrition and limited time for healthy food preparation due to homework emerged as key barriers to healthy eating. Conversely, insufficient exercise skills and reduced enjoyment of physical activity were the primary impediments to physical activity. Females perceived homework as a more substantial barrier than males (<i>p</i>=0.027). <b>Conclusion:</b> These barriers may contribute to increasing childhood obesity rates in Jordan. Future interventions should prioritize creating a supportive environment that respects cultural norms, emphasizing high-quality parks, nutrition and sports education, healthier food options, student motivation, and park visits. Community engagement is crucial for fostering healthier lifestyles among Jordanian youth.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"8889672"},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Healthy Lifestyles in Peruvian University Students During and After the COVID-19 Pandemic.","authors":"Carme Y Baltazar-Meza, María Custodio","doi":"10.1155/tswj/2664351","DOIUrl":"10.1155/tswj/2664351","url":null,"abstract":"<p><p>The COVID-19 pandemic has provoked a worldwide mental health crisis, affecting university students in an exacerbated way, exposing them to the risk of emotional isolation and development of eating disorders. The present study aimed to examine the quality of healthy lifestyle practices in university students from the Faculty of Human Medicine and the Faculty of Education of a Peruvian university during and after the COVID-19 pandemic. This study was conducted during the academic period 2020 and 2023. Data collection was performed between July and August 2020, during the first wave of the COVID-19 pandemic (M1) and between November and December 2023, post-pandemic (M2). In M1 and M2, 370 and 82 students participated, respectively. The results of the Mann-Whitney test revealed significant differences between the total healthy lifestyle score of students in M1 and M2. In the nutrition domain, there are significant differences between the scores obtained in M1 and M2, revealing a decrease in nutritional care. Significant differences were also found between both faculties in substance use in M1 and physical activity practice in M2. Although a trend toward the adoption of healthy habits was observed in the initial stages, the longitudinal analysis reveals a generalized decrease in concern for health and well-being. Medical students, on the other hand, showed greater resilience and more successful adaptation to new circumstances, evidencing the importance of academic training in the promotion of healthy lifestyles. These results underscore the need to implement intervention strategies aimed at promoting healthy habits in the student population, especially in contexts of health crisis.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"2664351"},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomised Controlled Trial Comparing Chemomechanical (Carie-Care™) Versus Conventional Caries Removal for Atraumatic Restorative Treatment.","authors":"Saloni Gupta, Kalyana Chakravarthy Pentapati, Shashidhar Acharya","doi":"10.1155/tswj/6689053","DOIUrl":"10.1155/tswj/6689053","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to evaluate and compare the clinical effectiveness of chemomechanical caries removal (CMCR) using Carie-Care™ versus conventional caries removal for atraumatic restorative treatment (ART). <b>Methods:</b> The study included 32 children aged 6-15 years with one or more one-surface cavitated carious lesions on the occlusal surface of permanent dentition. A total of 82 restorations were placed in permanent molars. The teeth were randomly assigned to two groups and monitored for 18 months after the intervention. For Group 1, Carie-Care™ gel was applied directly to the carious lesion, followed by cavity washing and gentle excavation using hand instruments. For Group 2, caries was removed using the mechanical method only. The success rate of the restorations, as well as the time taken and pain reactions measured by the sound eye motor (SEM) scale, were assessed between the two groups. <b>Results:</b> The SEM scores were significantly higher (<i>p</i>  <  0.05) in the conventional ART group than in the Carie-Care™ group. The mean time taken for caries removal in the Carie-Care™ group (731.15 ± 197.48 s) was significantly higher than in the ART group (596.66 ± 158.96 s) (<i>p</i> < 0.001). However, there was no significant difference in the clinical performance of Type IX restoration between the groups (<i>p</i>=0.69). <b>Conclusions:</b> The success rates of the restorations were similar between the two methods. However, the added advantage of less trauma associated with using a chemomechanical agent such as Carie-Care™ makes it an attractive option for community health and school dental programs.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"6689053"},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hadoop in Banking: Event-Driven Performance Evaluation.","authors":"Monalisa Panda, Mamata Garnayak, Mitrabinda Ray, Smita Rath, Anuradha Mohanta, Sushree Bibhuprada B Priyadarshini","doi":"10.1155/tswj/4375194","DOIUrl":"10.1155/tswj/4375194","url":null,"abstract":"<p><p>In today's data-intensive atmosphere, performance evaluation in the banking industry depends on timely and accurate insights, leading to better decision making and operational efficiency. Traditional methods for assessing bank performance often need to be improved to handle the volume, velocity, and variety of data generated in real time. This study proposes an event-driven approach for performance evaluation in banking alongside a Hadoop-based architecture. Infused with real-time event analytics, this scalable framework can process and analyze fast-moving transactional data. Hence, the framework allows banks to monitor key performance indicators and detect real-time operational anomalies. This is supported by the Hadoop ecosystem, which provides distribution of the processing and storage, making it fit for handling large datasets with high fault tolerance and parallel computation levels. This study analyzes transaction and user engagement data using Hive queries, focusing on credit card transactions via MasterCard. Two cases are examined: a detailed snapshot of individual transactions and a five-day trend analysis. Metrics like active users, card registrations, and retention are visualized through dashboards. Findings reveal user activity patterns and areas for improvement, emphasizing scalable, data-driven approaches for transaction analytics. This framework conceives a functional approach for banks to exploit extensive data-analytic capabilities to strive for competitive advantage and survivability of a business by adding any required metrics. The findings signify that the Hadoop-integrated event-driven analytics method could act as a game changer for performance evaluation in the banking sector.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"4375194"},"PeriodicalIF":0.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11774567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scale-Up of Tailor-Made Onsite Enzyme Blend From Cassava Peels for Industrial Bioethanol Production.","authors":"Martison Budu, Patrick Boakye, Joseph A Bentil","doi":"10.1155/tswj/2296078","DOIUrl":"10.1155/tswj/2296078","url":null,"abstract":"<p><p>Bioethanol production is one of the key alternatives for fossil fuel use due to climate change. The study seeks to upscale tailor-made onsite enzyme blends for the bioconversion of cassava peels to bioethanol in simultaneous saccharification and fermentation (SSF) process using cassava peels-degrading fungi. The starch and cellulose contents of peels were determined. The results showed significant levels of cellulose (39.78%) and starch (31.21%), indicating that cassava peels are valuable raw materials for bioethanol production. To investigate cassava-degrading microbes, <i>Aspergillus niger</i> demonstrated the highest enzyme activity with a diameter of zone of clearance of 16 mm. Tailor-made enzyme blends were produced with the <i>A</i>. <i>niger</i> using various substrate concentrations (1%, 3%, 5%, 8%, and 10%) of milled cassava peels at periods of 2, 4, 6, 8, and 10 days with a spore concentration of 2.1 × 10⁵ cells/mL. The amylolytic and cellulolytic activities were determined as 4.759 U/mL and 4.265 U/mL, respectively, at 5% and 6-day optimal conditions. The enzyme blend was upscaled using three fermentation vessels, thus 0.250 L flask, 1.0 L flask, and 10 L fermenter at optimized conditions in the SSF process for bioethanol production. These optimal conditions were firstly applied to a 0.250 L flask in the SSF process, a fixed enzyme dose of 20 mL and 1.5 g of <i>Saccharomyces cerevisiae</i> with varying substrate concentrations of 5%, 10%, and 20% and ethanol analyzed daily for 10 days. The theoretical ethanol yields recorded were 15.64%, 16.02%, and 14.91% for 0.250, 1, and 10 volumes obtained at different fermentation days. These optimized conditions demonstrate the potential for industrial bioethanol production in Ghana.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"2296078"},"PeriodicalIF":0.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11774575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Antibacterial Activities of <i>Croton macrostachyus</i> and <i>Pycnostachys abyssinica</i> Leaf Extracts Against Some Human Pathogens.","authors":"Getahun Yemata, Endalamaw Yihune, Yewulsew Kebede","doi":"10.1155/tswj/9481587","DOIUrl":"10.1155/tswj/9481587","url":null,"abstract":"<p><p>The present study was aimed to verify the medicinal value of <i>Croton macrostachyus</i> and <i>Pycnostachys abyssinica</i> traditionally used to treat human and animal ailments in Ethiopia. Fresh leaves of these species were collected, dried under shade, and ground into fine powder. The extraction was carried out by the maceration method using methanol as a solvent. The compounds in the crude extract were further profiled by thin layer chromatography (TLC). The antibacterial activity of the compounds was evaluated using the agar well diffusion method. <i>C</i>. <i>macrostachyus</i> had a higher percentage extract yield (22.5%) than <i>P</i>. <i>abyssinica</i> (13.7%). The phytochemical screening showed more abundant phenolic compounds and tannins in the extract of <i>C</i>. <i>macrostachyus</i> and alkaloid, flavonoid, phenolic compounds, and tannins in the extract of <i>P</i>. <i>abyssinica</i>. Overall, <i>C</i>. <i>macrostachyus</i> produced twofold higher growth inhibition zone (24.0 ± 0.5-43.0 ± 1.0 mm) against the tested pathogens than <i>P</i>. <i>abyssinica</i> (7.0 ± 0.5-24.0 ± 0.3 mm). Among the bacteria, <i>Klebsiella pneumoniae</i> was found to be the most sensitive to compounds of <i>C</i>. <i>macrostachyus</i>. The lowest minimum inhibitory concentration (MIC) values (25 mg/mL) were obtained from compounds 1 and 3 of <i>C</i>. <i>macrostachyus</i> leaf extract against <i>Escherichia coli</i> and <i>K</i>. <i>pneumoniae</i> and compounds 2 and 3 of the same against <i>S</i>. <i>aureus</i>. Similarly, compound 1 of <i>P</i>. <i>abyssinica</i> leaf extract produced the lowest MIC (25 mg/mL) against <i>K</i>. <i>pneumoniae</i> and <i>Staphylococcus epidermidis</i> and compound 3 of the same species against <i>E</i>. <i>coli</i> and <i>K</i>. <i>pneumoniae</i>. All the profiled compounds of the two species had both bactericidal and bacteriostatic properties against the tested pathogens. The results of the present study revealed that the compounds of <i>C</i>. <i>macrostachyus</i> had strong antibacterial activity against all the tested pathogens, indicating the high potential of the compounds. However, further characterization and identification of the specific compounds for the development of biocide formulations are suggested.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"9481587"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Multidomain Impact of Palliative Care on End-of-Life Patients: A Comprehensive Evaluation.","authors":"Mohammad O Abu Hasheesh","doi":"10.1155/tswj/4203906","DOIUrl":"10.1155/tswj/4203906","url":null,"abstract":"<p><p><b>Background:</b> Palliative care is recognized for its holistic approach in improving the quality of life for patients and their families, focusing on pain relief, symptom management, and addressing emotional, social, and spiritual needs. However, the field is evolving due to increasing demand for these specialized services, emphasizing the need for the ongoing research into palliative care practices. <b>Research Purpose:</b> Is to investigate the multidomain impact of palliative care on end-of-life patients and evaluate their effectiveness on these domains. <b>Method:</b> A quantitative descriptive design was adopted for conducting the current study. Approval obtained from a designated hospital in Amman, Jordan, and official permission to carry out the study. The study's participants consisted primarily of physicians and nurses who were involved in providing care to terminally ill patients. The research tool employed in this study is a standardized palliative care assessment that was used in Australia, with modifications based on the literature review. The validity and reliability of the adapted tool have been ensured through rigorous testing procedures. <b>Results:</b> Findings indicated that the implementation of standardized practical palliative care exhibited an average level across all domains, specifically, the spiritual domain received the highest mean score (1.80), while the structural domain had the lowest (1.69). There were significant differences in palliative care provision across specialized work sites, with radiotherapy and blood disease sites scoring higher (<i>M</i> = 2.04 and <i>M</i> = 1.87, respectively). Educational levels significantly influenced care perceptions, favoring BSc holders. Age did not significantly affect palliative care provision, probably because of standardized care protocols and sample size. In addition, nurses rated palliative care higher than physicians, likely due to their more direct patient involvement. <b>Conclusion:</b> In light of the results, it is evident that there is a pressing need to consistently evaluate the healthcare services offered to meet the needs of the increasing population of terminally ill patients.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"4203906"},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic and Environmental Impacts of <i>Eucalyptus</i> Plantations in Ethiopia: An Evaluation of Benefits, Challenges, and Sustainable Practices.","authors":"Kiros Getachew Belachew, Wondwosson Kibrie Minale","doi":"10.1155/tswj/1780293","DOIUrl":"10.1155/tswj/1780293","url":null,"abstract":"<p><p><i>Eucalyptus</i> was first introduced to Ethiopia in the late 19^th century to address the scarcity of firewood and construction wood in the capital city. Since then, it has spread across the country and has become an important source of income for many households while also reducing the need for deforestation. Despite concerns raised by environmentalists about its eco-hydrological impact, the plantation has expanded to cover a vast area of the nation, including farmlands and mountainous regions. Currently, around 506,000 hectares of land in Ethiopia are covered by <i>Eucalyptus</i> plantations. The growth of <i>Eucalyptus</i> plantations can be attributed to various socioeconomic, ecological, and biological factors, including the increasing demand for wood and wood products. However, this growth has also led to negative environmental consequences such as reduced surface and groundwater flow, decreased crop productivity, soil fertility degradation and depletion, and high water consumption, which can result in water scarcity. To address these environmental impacts, it is essential to select appropriate species and sites and implement proper silvicultural and land use planning before planting. Additionally, promoting renewable energy sources and planting environmentally sound fast-growing indigenous and exotic tree species can help reduce the adverse effects of <i>Eucalyptus</i> on the environment.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"1780293"},"PeriodicalIF":0.0,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficiency of Polyethylene Terephthalate Glycol Thermoplastic Material to Functional and Expansion Forces in Orthodontic Applications: An Experimental Study.","authors":"Anosh A Haik, Yassir A Yassir","doi":"10.1155/tswj/7232779","DOIUrl":"10.1155/tswj/7232779","url":null,"abstract":"<p><p><b>Background:</b> While polyethylene terephthalate glycol (PETG) is widely used in orthodontic appliances such as clear aligners and retainers, there is limited experimental data assessing its performance under functional stresses, such as those encountered during dental movements and palatal expansion. <b>Objective:</b> This study aims to evaluate the ability of PETG thermoplastic material to withstand deformation under functional and expansion forces, specifically within the context of orthodontic applications. <b>Subjects and Methods:</b> To estimate the firmness of the screw within the appliance, a universal Instron testing machine was used to record the forces released by each activation of the expander within the upper part of 10 clear modified twin blocks (MTBs) made from PETG and compare it with that released by 10 conventional twin blocks (CTBs). On the other hand, to determine the ability of the thermoplastic appliance to withstand the deformation during functional forces, a three-point bending test was used to investigate the response of both appliances under static loading. Independent samples <i>t</i>-test was used to compare the differences between groups. <b>Results:</b> Both CTB and MTB groups follow the same pattern of increase and decrease in the amount of mean load with the CTB group line showing a considerably higher amount of mean load reaching the peak (334.5 N) at turn 25 of screw activation while the peak of mean load for MTB group was equal to 252.6 N at turn 23. There was a statistically significant difference between the CTB and MTB groups in the three-point bending test (<i>p</i>=0.001). However, both appliances did not deform at the required force. <b>Conclusions:</b> The MTB can withstand both required expansion and functional load without deformation. <b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT06116500.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"7232779"},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Contemporary Insight Into the Seroepidemiology of Herpes Simplex Virus Infection in the Sub-Himalayan Region: Seroepidemiology of HSV Infection in North India.","authors":"Sangeeta Deka, Mithilesh Kumar Jha, Pratima Gupta, Putul Mahanta, Deepjyoti Kalita","doi":"10.1155/2025/6826627","DOIUrl":"10.1155/2025/6826627","url":null,"abstract":"<p><p>Infection by human herpes simplex virus type 1 and type 2 (HSV-1/2) is common globally though with wide regional variability. Seroepidemiology of HSV-1/2 infections is of utmost importance in formulating control strategies, but there is a paucity of data from many regions of India. This study aimed to determine the prevalence of anti-HSV-1/2 antibodies in Uttarakhand and adjoining areas and to study its pattern and distribution in different subgroups. Serum samples from 322 cases were subjected to ELISA test to check for the presence of anti-HSV-1/2 IgG and IgM antibodies. Sociodemographic and clinical information were extracted from medical records. The association of seropositivity and associated factors was analyzed using Fisher's exact test. The overall HSV-1/2 seropositivity was observed to be 46.0% (95% confidence interval [CI]: 40.5-51.4). Total IgM and IgG were found in 6.2% (95% CI: 3.6-8.8) and 45.3% (95% CI: 38.1-48.9) cases, respectively. No significant difference between seropositivity of males and females was observed (45.7% in males versus 46.2% in females; <i>p</i> value: 0.928). Seroprevalence increased with age in both genders but was more pronounced in males (<i>p</i> value: <0.001), while 50.6% of women in the reproductive age group (18-30 years) were found to be seropositive. Females from Uttarakhand, compared to adjoining states (<i>p</i> value: 0.041) and both men and women residing in hilly terrain compared to plains (<i>p</i> value: 0.018; <i>p</i> value: 0.030), showed significantly lower prevalence, while urban-dwelling men showed higher seropositivity (<i>p</i> value: 0.048). Thus, HSV-1/2 seroprevalence is lower in this region, especially in young, rural, and hill dwellers, indicating majority are vulnerable to acquiring new infections. More awareness among high-risk groups and implementation of targeted public health policies can help control the disease burden.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"6826627"},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}