The Scientific World Journal最新文献

New Streptomyces-Derived Antibacterial Compounds Targeting Gram-Positive Bacteria: A Systematic Review. 针对革兰氏阳性菌的新型链霉菌衍生抗菌化合物：系统综述。

The Scientific World Journal Pub Date : 2025-09-24 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/6659874

Soumia Ait Assou, Mohammed El Hassouni

{"title":"New Streptomyces-Derived Antibacterial Compounds Targeting Gram-Positive Bacteria: A Systematic Review.","authors":"Soumia Ait Assou, Mohammed El Hassouni","doi":"10.1155/tswj/6659874","DOIUrl":"10.1155/tswj/6659874","url":null,"abstract":"Bacterial infections, particularly those caused by Gram-positive bacteria like vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA), are a growing concern. This review highlights the potential of the Streptomyces genus in producing novel antibacterial compounds against Gram-positive bacteria. The study was carried out following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). To gather relevant literature on novel anti-Gram-positive bacteria compounds produced by Streptomyces, a web search was conducted using several databases, including Scopus, PubMed, ScienceDirect, and Google Scholar, covering the period from January 2013 to mid-2024. The search terms employed in this study included \"Streptomyces,\" \"antimicrobial/antibacterial activity,\" \"compounds,\" and \"Gram-positive bacteria.\" Consequently, a total of 248 Streptomyces-derived compounds were featured across the 96 eligible studies. These compounds include 100 polyketides (58 aromatic polyketides, 30 macrolides, and 12 other polyketides), 72 peptides (67 nonribosomal peptides [52 typical cyclic peptides and 15 lipopeptides] and 5 ribosomal peptides), 23 terpenoids, five polyketides-terpenoids, six alkaloids, 12 phenazines, 11 nucleoside antibiotics, and 19 other compounds belonging to distinct chemical classes. The results emphasize that Streptomyces is an unlimited source of naturally occurring compounds with various structural variations that can occasionally have targeted action against a range of pathogenic Gram-positive bacteria.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"6659874"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a New Index to Assessing the Safety Culture Based on the Edgar Schein Model (Audit Approach). 基于Edgar Schein模型（审计方法）的安全文化评价新指标的建立。

The Scientific World Journal Pub Date : 2025-09-24 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/3166187

Davood Eskandari, Abbas Haghparast Ghomesheh, Mousa Jabbari, Abdollah Gholami, Omran Ahmadi

{"title":"Development of a New Index to Assessing the Safety Culture Based on the Edgar Schein Model (Audit Approach).","authors":"Davood Eskandari, Abbas Haghparast Ghomesheh, Mousa Jabbari, Abdollah Gholami, Omran Ahmadi","doi":"10.1155/tswj/3166187","DOIUrl":"10.1155/tswj/3166187","url":null,"abstract":"Introduction: Over the past few decades, particularly following the Chernobyl incident, awareness of the importance of safety culture has increased significantly. Traditionally, safety culture has been assessed using questionnaires, with results often influenced by employees' psychological states. Therefore, the present study evaluates safety culture through an audit-based approach, employing performance indicators grounded in Edgar Schein's model. Materials and Methods: To identify the key factors contributing to the safety culture index, Edgar Schein's model was applied. Relevant indicators were derived across three levels: artifacts, espoused values, and basic assumptions. The fuzzy analytic hierarchy process (FAHP), combined with expert evaluations, was used to determine the relative importance of these criteria. Finally, the company's safety culture index was quantitatively assessed using guide tables and the weighted contribution of each factor. Results: Then, 10 indicators were identified across the three levels of Schein's model: quality of documentation and procedures, employee involvement, management of professional competence, change management, organizational learning, openness and communication, prioritization of safety, managerial knowledge, safety perspectives, and attitudes toward mistakes. According to the FAHP results, prioritization of safety had the highest weight (0.157), while quality of documentation and procedures had the lowest weight (0.026) in the safety culture index. Discussion: An audit-based approach proves more effective than questionnaire methods for quantitatively assessing safety culture.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"3166187"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adoption of Soil and Water Conservation Practices and Farmer Perceptions of Soil Erosion: Implications for Sustainable Agriculture in Soro District, Central Ethiopia. 水土保持措施的采用和农民对土壤侵蚀的认识：对埃塞俄比亚中部索罗地区可持续农业的影响。

The Scientific World Journal Pub Date : 2025-09-19 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/5192374

Esiyas Estefanos, Belayneh Bufebo, Tamene Betebo

{"title":"Adoption of Soil and Water Conservation Practices and Farmer Perceptions of Soil Erosion: Implications for Sustainable Agriculture in Soro District, Central Ethiopia.","authors":"Esiyas Estefanos, Belayneh Bufebo, Tamene Betebo","doi":"10.1155/tswj/5192374","DOIUrl":"10.1155/tswj/5192374","url":null,"abstract":"Soil erosion remains a critical environmental and agricultural challenge in Ethiopia, particularly in highland areas such as the Soro District of Central Ethiopia, where land degradation directly threatens agricultural productivity and rural livelihoods. This study was undertaken to better understand the key factors influencing smallholder farmers' adoption of soil and water conservation practices, along with their perceptions of soil erosion and its impacts. The study employed a mixed methods approach, combining household surveys, focus group discussions, and field observations to gather both quantitative and qualitative data from a representative sample of smallholder farmers. Descriptive analysis, principal component analysis, and probit regression models were used to analyze the collected data. Probit regression analysis revealed that factors such as sex, education, size of farmland, interactions with extension services, participation in conservation training, and household income all played a significant and positive role in encouraging the adoption of soil and water management practices. In contrast, soil fertility was found to have a negative effect on the uptake of soil and water conservation techniques. Farmers perceived damaged conservation structures, soil loss, and farmland fragmentation as key consequences of severe soil erosion. While most farmers recognize soil erosion as a major threat to their land, adoption rates of sustainable practices remain uneven due to economic, institutional, and knowledge-based constraints. The study underscores the importance of integrating local perceptions into policy frameworks and promoting participatory approaches to enhance the uptake of conservation practices. These insights contribute to the design of more effective and context-specific land management strategies aimed at ensuring long-term environmental sustainability and agricultural resilience in the region.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"5192374"},"PeriodicalIF":0.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12473740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of BSL-3 Laboratories in Pandemic Preparedness: A Focus on Brazil's Infrastructure for Biosafety and Disease Control. BSL-3实验室在大流行病防范中的作用：重点关注巴西生物安全和疾病控制基础设施。

The Scientific World Journal Pub Date : 2025-09-18 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/9104904

Roni Vinhas, Fabricia Oliveira, Larissa Fonseca, Katharine Hodel, Claudio Mafra, Cíntia Minafra, Marilda Gonçalves, Bruna Machado

{"title":"The Role of BSL-3 Laboratories in Pandemic Preparedness: A Focus on Brazil's Infrastructure for Biosafety and Disease Control.","authors":"Roni Vinhas, Fabricia Oliveira, Larissa Fonseca, Katharine Hodel, Claudio Mafra, Cíntia Minafra, Marilda Gonçalves, Bruna Machado","doi":"10.1155/tswj/9104904","DOIUrl":"10.1155/tswj/9104904","url":null,"abstract":"BSL-3 laboratories are fundamental for the safe handling of infectious microorganisms that require high-containment measures. Through a literature review, this work was aimed at highlighting the importance of these laboratories in supporting research and public health responses, especially during health emergencies. The review presents an overview of the global distribution of BSL-3 facilities, the impacts of the COVID-19 pandemic on laboratory investments, and future perspectives on their role in national development. It was observed that the pandemic exposed limitations in laboratory capacity, leading many countries to operate in suboptimal environments, underscoring the need for strict biosafety standards and preparedness infrastructure. This review also identifies disparities in global BSL-3 capacity-particularly in low- and middle-income countries-and examines the Brazilian context, where the absence of a unified regulatory framework hinders progress. By synthesizing international trends and Brazil's recent initiatives, including the development of its first BSL-4 laboratory, this work contributes to understanding the challenges and opportunities for strengthening biosafety infrastructure in support of equitable pandemic preparedness.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"9104904"},"PeriodicalIF":0.0,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of 6-Min Mastication Test on Masticatory Function in Young Versus Older Adults: A Comparative SEMG Study. 6分钟咀嚼试验对年轻人和老年人咀嚼功能的影响：一项比较的肌电图研究。

The Scientific World Journal Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/1506278

Uzair Chilwan, Sahlah Shameer, Aysha Hanan, Radish Kumar Balasubramanium

{"title":"Effect of 6-Min Mastication Test on Masticatory Function in Young Versus Older Adults: A Comparative SEMG Study.","authors":"Uzair Chilwan, Sahlah Shameer, Aysha Hanan, Radish Kumar Balasubramanium","doi":"10.1155/tswj/1506278","DOIUrl":"10.1155/tswj/1506278","url":null,"abstract":"Introduction: Aging impacts masticatory and swallowing functions due to muscle atrophy, neural degeneration, and reduced endurance. This study evaluated age-related differences in masticatory muscle function using the 6-min mastication test (6MMT) with surface electromyography (SEMG). Methodology: The study included two groups: healthy young adults (18-35 years) and healthy older adults (60 years and above). Muscle activity of the masseter and submental muscles was recorded using electrodes during mastication. Participants were instructed to chew bubble gum in synchronization with a metronome set at 80 bpm, with verbal reinforcement provided every minute. Results: Results revealed significant age-related differences in the masseter muscle for all parameters and in the submental muscle for peak values. Older adults demonstrated reduced masticatory muscle performance, attributed to sarcopenia, neural degeneration, and increased noncontractile tissue. Within-group analysis showed progressive changes in submental muscle mean average and power values over the 6-min task, reflecting fatigue, while no significant differences were observed in masseter muscle parameters in healthy young adults, possibly due to a warm-up effect or compensatory motor unit recruitment. Conclusion: The study demonstrated that masseter muscle activity significantly declines with age, with large effect sizes observed for all the parameters. Additionally, fatigue-related reductions in submental muscle parameters were observed across both age groups. These findings suggest that age-related and task-induced fatigue differentially affect masticatory muscles, highlighting the need for tailored interventions to support oral function in older adults.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"1506278"},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating Mental Health Screening in Community Pharmacies: Knowledge, Attitudes, and Perceived Barriers Among Pharmacy Students. 整合社区药房心理健康筛查：药学学生的知识、态度和感知障碍。

The Scientific World Journal Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/9769309

Amjad H Bazzari, Firas H Bazzari

{"title":"Integrating Mental Health Screening in Community Pharmacies: Knowledge, Attitudes, and Perceived Barriers Among Pharmacy Students.","authors":"Amjad H Bazzari, Firas H Bazzari","doi":"10.1155/tswj/9769309","DOIUrl":"10.1155/tswj/9769309","url":null,"abstract":"Mental health disorders remain a significant global burden, and access to timely mental healthcare remains limited. Community pharmacies, given their accessibility to the public, are well-positioned for early mental health screening. Here, we aimed to assess pharmacy students' knowledge, attitudes, and perceived barriers in this regard. The study was conducted via a printed questionnaire, and a total of 211 students, with a mean age of 23.3 ± 3.32 years, participated, including males (35.55%) and females (64.45%). Most students agreed that they are familiar with common mental health disorders (44.08%) and the roles of pharmacists in mental healthcare (38.39%), but were neutral in terms of their ability to identify signs and symptoms (43.13%), awareness of mental health screening tools (32.7%), and confidence in their ability to perform screening (28.44%), with males reporting higher awareness and confidence (p < 0.05) than females. In terms of attitudes, the majority strongly agreed that mental healthcare is essential (50.24%), and most agreed that pharmacists are well-positioned for mental health screening (40.28%) and that screening can improve patient outcomes (39.81%), reduce stigma (37.44%), and should be a routine pharmacy practice (30.81%). The overall score of self-perceived knowledge was 59%, while that for positive attitude was 69%. Lastly, the participants moderately agreed on several potential barriers, including time constraints, lack of pharmacist training or education, lack of sufficient privacy, patient reluctance to share and communicate, and stigma toward mental illness among pharmacists, with agreement scores ranging from 53.25% to 64.75%. The results indicate a low level of perceived knowledge, moderately positive attitudes, and relative awareness of the potential barriers, suggesting a need for improved awareness and education in this regard.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"9769309"},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Removal of Pb (II) Ions from Aqueous Solutions by Cladophora rivularis (Linnaeus) Hoek. 缩回：Cladophora rivularis (Linnaeus) Hoek从水溶液中去除Pb （II）离子。

The Scientific World Journal Pub Date : 2025-09-12 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/9813586

The Scientific World Journal

引用次数: 0

Understanding the Impact of Livelihood Diversification on Food Security Among Smallholder Farmers in West Gojjam Zone, Amhara Region, Ethiopia. 了解生计多样化对埃塞俄比亚阿姆哈拉地区西Gojjam地区小农粮食安全的影响。

The Scientific World Journal Pub Date : 2025-09-12 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/6095651

Silabat Enyew Zewudie

{"title":"Understanding the Impact of Livelihood Diversification on Food Security Among Smallholder Farmers in West Gojjam Zone, Amhara Region, Ethiopia.","authors":"Silabat Enyew Zewudie","doi":"10.1155/tswj/6095651","DOIUrl":"10.1155/tswj/6095651","url":null,"abstract":"Background: Livelihood diversification is widely recognized as a vital strategy for improving food security among smallholder rural households. However, achieving meaningful diversification remains a challenge due to various socioeconomic and institutional constraints. This study investigates the impact of livelihood diversification on food security in the West Gojjam Zone of Ethiopia. Methods: A cross-sectional research design was employed using primary data collected from 390 randomly selected smallholder farmers through a multistage sampling technique. Binary logistic regression was used to identify factors influencing livelihood diversification, while Propensity score matching (PSM) was applied to estimate its causal impact on food security. Robust standard errors were reported to address potential heteroscedasticity, and diagnostic tests confirmed no major multicollinearity or model misspecification issues. Key Results: Among the sampled households, 108 engaged in livelihood diversification. Regression results revealed that education (+15.4%) and household size (+5.9%) significantly increased the likelihood of diversification, whereas access to irrigation (-35.7%), livestock ownership (-2.9%), and credit access (-12.08%) negatively affected it. PSM analysis confirmed a positive and statistically significant impact of diversification on food security, increasing daily kilocalorie intake by 118-136 kcal. Conclusion/Policy Implications: The findings suggest that livelihood diversification significantly enhances food security among smallholder farmers. Therefore, policies should promote diversification through expanded irrigation infrastructure, vocational training (TVET and universities), and support for activities such as animal fattening, dairy farming, and beekeeping. Extension services and microfinance institutions should be mobilized to provide technical and financial support focused on diversified farming strategies.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"6095651"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to "Efficient Removal of Brilliant Green Dye Using Mesoporous Attapulgite Clay: Investigating Adsorption Kinetics, Isotherms, and Mechanisms". “使用介孔凹凸棒石粘土有效去除亮绿色染料：研究吸附动力学、等温线和机理”的勘误。

The Scientific World Journal Pub Date : 2025-09-03 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/9804935

引用次数: 0

Effectiveness of First Aid Training at Home for Grandparents Caring Grandchildren Under 5 Years Old: A Randomized Controlled Trial. 一项随机对照试验：祖父母在家照顾5岁以下孙辈急救训练的有效性。

The Scientific World Journal Pub Date : 2025-09-02 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/7457823

Atefeh Rahim, Abdolrahim Asadollahi, Mehdi Mojadam, Eva Dolenc Šparovec, Mansour Kashfi, Mahin Nazari

{"title":"Effectiveness of First Aid Training at Home for Grandparents Caring Grandchildren Under 5 Years Old: A Randomized Controlled Trial.","authors":"Atefeh Rahim, Abdolrahim Asadollahi, Mehdi Mojadam, Eva Dolenc Šparovec, Mansour Kashfi, Mahin Nazari","doi":"10.1155/tswj/7457823","DOIUrl":"10.1155/tswj/7457823","url":null,"abstract":"Background: This study is aimed at raising awareness about home accidents among grandparents caring for their grandchildren and reducing the risk of accidents and premature death in children under five through structured first aid training. Methods: In this randomized controlled trial, 76 older adults from a daycare center in Shiraz, Iran, were randomly assigned to either an intervention group or a control group. The intervention group participated in eight sessions of first aid training. Pre- and postintervention assessments included PMT-based questionnaires and practical first aid skill tests. Data were analyzed using SPSS and JAMOVI. Results: Significant improvements were observed in the intervention group compared to the control group in terms of first aid knowledge (p < 0.001), home accident prevention (p < 0.001), and practical first aid skills (p < 0.001). Effect size analyses (Cohen's d > 0.80) further supported the substantial impact of the intervention across all measured domains. Conclusions: First aid training based on protection motivation theory significantly enhanced older adults' preparedness in preventing and managing home accidents involving their grandchildren. These findings underscore the importance of integrating first aid education into geriatric caregiving programs. Trial Registration: Iranian Registry of Clinical Trials number: IRCT20180514039648N6.","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"7457823"},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0