A Roadmap for the Application of Convalescent Plasma and Hyperimmune Globulins in Emerging Viral Outbreaks.

Q2 Environmental Science
The Scientific World Journal Pub Date : 2025-07-03 eCollection Date: 2025-01-01 DOI:10.1155/tswj/9976167
Aliasghar Rahimian, Hooman Askari, Ali Nabati, Mahdi Aminian
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引用次数: 0

Abstract

The outbreak of COVID-19 took the world by surprise and dealt a serious blow to the global economy. Even today, few drugs against SARS-CoV-2 infection have been proven useful, and repurposing existing antiviral therapies remains a major research area in the treatment of the disease. During previous viral outbreaks, therapies using convalescent plasma and related products have repeatedly been used as empirical approaches. Rapid preparation of convalescent plasma and hyperimmune globulins (hIVIGs) makes these two treatment options useful in dealing with outbreaks of emerging diseases. The current study presents a systematic roadmap concerning the guidelines, criteria, and regulations involved in plasma transfusion and the preparation of hIVIGs applicable to possible future viral outbreaks.

恢复期血浆和高免疫球蛋白在新出现的病毒暴发中的应用路线图。
新冠肺炎疫情震惊世界,给全球经济造成严重打击。即使在今天,针对SARS-CoV-2感染的药物也很少被证明是有用的,重新利用现有的抗病毒疗法仍然是治疗该疾病的一个主要研究领域。在以前的病毒爆发期间,使用恢复期血浆和相关产品的治疗已多次被用作经验方法。快速制备恢复期血浆和高免疫球蛋白(hIVIGs)使这两种治疗方案在应对新发疾病暴发时非常有用。目前的研究提出了一个系统的路线图,涉及血浆输血和hIVIGs制备的指南、标准和法规,适用于未来可能的病毒暴发。
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来源期刊
The Scientific World Journal
The Scientific World Journal 综合性期刊-综合性期刊
CiteScore
5.60
自引率
0.00%
发文量
170
审稿时长
3.7 months
期刊介绍: The Scientific World Journal is a peer-reviewed, Open Access journal that publishes original research, reviews, and clinical studies covering a wide range of subjects in science, technology, and medicine. The journal is divided into 81 subject areas.
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