The Scientific World Journal最新文献

筛选
英文 中文
Assessment of the Knowledge of Chronic Kidney Disease and Anemia Among University Students in Ghana: A Cross-Sectional Study. 加纳大学生对慢性肾病和贫血知识的评估:一项横断面研究
The Scientific World Journal Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/9993948
Israel A Sarfo, Benedicta Boakye, Henrietta Eshun, Emmanuel Jingbeja, Abigail Asmah-Brown, Patrick Adu, Joseph Boachie
{"title":"Assessment of the Knowledge of Chronic Kidney Disease and Anemia Among University Students in Ghana: A Cross-Sectional Study.","authors":"Israel A Sarfo, Benedicta Boakye, Henrietta Eshun, Emmanuel Jingbeja, Abigail Asmah-Brown, Patrick Adu, Joseph Boachie","doi":"10.1155/tswj/9993948","DOIUrl":"https://doi.org/10.1155/tswj/9993948","url":null,"abstract":"<p><p><b>Background:</b> Chronic kidney disease (CKD) is typically associated with anemia, with both implicated in global mortalities and morbidities. Adequate knowledge about these conditions might help individuals to prevent and/or manage them effectively. This study was aimed at assessing the knowledge of CKD and anemia regarding their causes, risk factors, and preventive practices among undergraduate students. <b>Methods:</b> The study was a cross-sectional design conducted from July 2023 to September 2023, involving 267 students pursuing either health-related or nonhealth-related programs. A structured questionnaire was administered to participants to assess their knowledge of CKD and anemia and was analyzed. <b>Results:</b> An overwhelming majority, 208 (77.9%), demonstrated a good level of general knowledge of CKD, whereas an even higher proportion, 215 (80.5%), had a good level of general knowledge of anemia. Also, the bulk of the participants, 222 (83.1%), showed a good level of knowledge of the relationship between CKD and anemia. There was a significant relationship between a student's faculty and general CKD knowledge (<i>p</i> < 0.001). Participants in health-related faculties and in the third/fourth year significantly had good knowledge of CKD than those in nonhealth-related faculties and in the first/second year of studies. With regards to anemia, individuals aged 20 years and beyond had good knowledge of anemia than teenage students. There was also a significant relationship between a student's faculty and general knowledge of anemia (<i>p</i> < 0.001), such that participants in health-related faculties were about 99% less likely to have poor knowledge of anemia than those in nonhealth-related faculties [AOR = 0.01 (0.00, 0.007)]. <b>Conclusion:</b> Students with good knowledge of CKD, anemia, and/or their interrelationships were the majority. However, students in health-related faculties significantly had good knowledge of both CKD and anemia than their counterparts in nonhealth-related faculties. Health-related courses that would enlighten students in nonhealth-related faculties should be promoted.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"9993948"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Additional Structured Strength Training of Unaffected Lower Extremity on Balance and Gait Among Acute Poststroke Individuals. 急性脑卒中后患者未受影响的下肢额外结构化力量训练对平衡和步态的影响。
The Scientific World Journal Pub Date : 2025-04-02 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/1663116
Neha Kumari, Akshatha Nayak, Abraham M Joshua, Shivananda D Pai, Shyam Krishnan Krishna Kumar, Rinita Mascarenhas, Shreekanth D Karnad
{"title":"Effectiveness of Additional Structured Strength Training of Unaffected Lower Extremity on Balance and Gait Among Acute Poststroke Individuals.","authors":"Neha Kumari, Akshatha Nayak, Abraham M Joshua, Shivananda D Pai, Shyam Krishnan Krishna Kumar, Rinita Mascarenhas, Shreekanth D Karnad","doi":"10.1155/tswj/1663116","DOIUrl":"https://doi.org/10.1155/tswj/1663116","url":null,"abstract":"<p><p><b>Introduction:</b> Stroke reduces lower extremity muscle strength bilaterally, predominantly on the affected side. Stroke rehabilitation focuses on training the hemiparetic extremities, whereas functional activities require the recruitment of bilateral lower extremity muscles. <b>Objectives:</b> This research is aimed at studying the effectiveness of additional structured strength training of unaffected lower extremity (ULE) on balance and gait among acute poststroke individuals. <b>Methods:</b> This Nonrandomized Controlled Trial included 28 clinically stable acute poststroke individuals aged 20-80 years, with the first episode of stroke, and who could walk 5 m with or without assistive devices. The subjects were assigned to either an experimental group (<i>n</i> = 14) or a control group (<i>n</i> = 14). Both groups received 12 sessions of conventional stroke rehabilitation focusing on the affected side. In addition, individuals in the experimental group received structured strength training for the ULE. <b>Main Outcome Measure:</b> Balance, gait, and muscle strength of the ULE were measured pre and after 2 weeks of intervention using Brunel Balance Assessment (BBA), Wisconsin Gait Scale (WGS), 2D gait analysis (Kinovea software), and a handheld dynamometer, respectively. <b>Results:</b> The strength in the ULE of the experimental group improved significantly in all the muscle groups, whereas the control group showed improvements only in hip flexors, hip extensors, knee flexors, and ankle dorsiflexors. However, the strength gains in the hip flexors, hip abductors, knee extensors, and ankle dorsiflexors were significantly greater in the experimental group. Additionally, there was a significant difference among the groups in the BBA (<i>p</i> = 0.001) and WGS scores (<i>p</i> = 0.012). The kinematic variables of gait showed better knee flexion (<i>p</i> = 0.006), dorsiflexion angles (<i>p</i> = 0.016), and gait speed (<i>p</i> = 0.008) in the experimental group. <b>Conclusion:</b> Additional structured lower extremity strengthening of the ULE led to improved strength of ULE, resulting in better balance function and gait among individuals with acute stroke. <b>Trial Registration:</b> ClinicalTrials.gov identifier: CTRI/2018/12/016685.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"1663116"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Threshold Setting for Event Log Repair on Conformance Checking. 事件日志修复阈值设置对一致性检查的影响。
The Scientific World Journal Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/4028269
Kazuki Masumoto, Hiroki Horita
{"title":"Impact of Threshold Setting for Event Log Repair on Conformance Checking.","authors":"Kazuki Masumoto, Hiroki Horita","doi":"10.1155/tswj/4028269","DOIUrl":"https://doi.org/10.1155/tswj/4028269","url":null,"abstract":"<p><p>Conformance checking is a method to compare the actually executed business process recorded as an event log with the business process described as a business process model and to identify differences. For human or technical reasons, event logs that contain noise and are of low quality may be recorded. Therefore, methods have been proposed to repair low-quality event logs, but they require the setting of a threshold, and it is difficult to set a suitable threshold. In this paper, we investigate the effect of low-quality event log repair methods on conformance checking. Through experiments, it was shown that the appropriate threshold depends on the type of event log and the amount of noise.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"4028269"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silage Characteristics of Selected Forage Maize Varieties Harvested in Sole and Forage Legume Mixtures. 精选饲料玉米品种在比目鱼和豆科牧草混合中青贮特性的研究。
The Scientific World Journal Pub Date : 2025-03-28 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/2270637
Poloko Mosebi, Moeketsi Ntakatsane, Tumelo Nkheloane, Tumelo Manyeli, Palo Loke
{"title":"Silage Characteristics of Selected Forage Maize Varieties Harvested in Sole and Forage Legume Mixtures.","authors":"Poloko Mosebi, Moeketsi Ntakatsane, Tumelo Nkheloane, Tumelo Manyeli, Palo Loke","doi":"10.1155/tswj/2270637","DOIUrl":"10.1155/tswj/2270637","url":null,"abstract":"<p><p>The present study was conducted to evaluate the ensiling characteristics of selected forage maize varieties harvested in sole and forage legume mixtures. Two different forage maize varieties were harvested in different forage systems, that is, sole maize, maize + common vetch and maize + lablab intercrops, and ensiled in small-scale silos. After ensiling, samples were collected to examine the nutrient composition, fermentation quality and microbial population. Ensiled forage varieties harvested in sole forage systems had a significantly (<i>p</i> < 0.05) lower dry matter and crude protein contents (31.18% and 7.15% DM, respectively) than that from forage legume mixtures. Forage legume mixtures had significantly (<i>p</i> < 0.05) lower neutral detergent and acid detergent fibre contents (24.42% and 35.53% DM, respectively) and higher water-soluble carbohydrates (12.34% DM) in silage of selected varieties than sole forage systems. The pH value and ammonia nitrogen content of ensiled forage varieties were lower, while lactic acid production (7.25% DM) was greater in forage legume mixtures than in sole forage system. Lower acetic and propionic acid and higher butyric acid contents (1.06%, 0.84% and 0.46% DM, respectively) were observed in sole forage system for silage of selected varieties compared to forage legume mixtures. Sole forage systems showed lower numbers of lactic acid bacteria and higher populations of enterobacteria (4.31 and 4.34 log<sub>10</sub> cfug<sup>-1</sup>, respectively) in silages of selected varieties than forage legume mixtures. The study concluded that ensiling forage materials harvested in forage intercrops have a positive effect on the silage quality. Therefore, the recommended forage system for ensiling is forage legume mixtures.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"2270637"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Gas-Sensing Performances of Mn3O4-Decorated Cr2O3 Nanoparticle for H2S Detection. 用于H2S检测的mn3o4修饰Cr2O3纳米颗粒的合成及其气敏性能
The Scientific World Journal Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/8845797
Hawraa Kassem Hami, Hussain Ismail Abdulah
{"title":"Synthesis and Gas-Sensing Performances of Mn<sub>3</sub>O<sub>4</sub>-Decorated Cr<sub>2</sub>O<sub>3</sub> Nanoparticle for H<sub>2</sub>S Detection.","authors":"Hawraa Kassem Hami, Hussain Ismail Abdulah","doi":"10.1155/tswj/8845797","DOIUrl":"10.1155/tswj/8845797","url":null,"abstract":"<p><p>Mn<sub>3</sub>O<sub>4</sub> decorated with Cr<sub>2</sub>O<sub>3</sub> was prepared via a cost-effective and straightforward photolysis method and utilized as an H<sub>2</sub>S gas sensor. The nanocomposite exhibited excellent chemical sensing properties toward H<sub>2</sub>S gas at 200°C, achieving a sensitivity of 89.93. A proposed sensing mechanism highlights the synergistic roles of Mn<sub>3</sub>O<sub>4</sub> and Cr<sub>2</sub>O<sub>3</sub> in gas detection. This study underscores the potential of Mn<sub>3</sub>O<sub>4</sub>-Cr<sub>2</sub>O<sub>3</sub> composites in industrial and environmental monitoring applications, offering a reliable and efficient solution for detecting hazardous gases.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"8845797"},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing Urban Food Security Challenges in Gondar, Ethiopia: A Systematic Study on Household Vulnerability and Policy Implications. 评估埃塞俄比亚贡达尔的城市粮食安全挑战:关于家庭脆弱性和政策影响的系统研究。
The Scientific World Journal Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/5867354
Ishfaq Ahmad Malik, Showkat Ahmad Shah
{"title":"Assessing Urban Food Security Challenges in Gondar, Ethiopia: A Systematic Study on Household Vulnerability and Policy Implications.","authors":"Ishfaq Ahmad Malik, Showkat Ahmad Shah","doi":"10.1155/tswj/5867354","DOIUrl":"10.1155/tswj/5867354","url":null,"abstract":"<p><p>Food security is a paramount issue, particularly in developing nations like Ethiopia. Much of the existing research focuses on identifying the factors and constraints of households related to rural areas. However, little attention has been paid to urban householders' food security and insecurity. To this end, a study has been conducted in Gondar to evaluate urban household food security, sampling 357 homes. Results revealed that 67% of male-headed households were food secure and 33% were food insecure, while 72% of female-headed households were found food insecure and 28% were found food secure. Tenants faced higher insecurity (77%) versus homeowners (12%). The Foster-Greer-Thorbecke model highlighted 53% incidence, 14% depth, and 5.4% severity of insecurity. Tackling 15% of calorie needs could eradicate it with proactive regional governance. Binary logistic modelling identified gender, homeownership, income, marital status, remittance, and credit access as significant factors (<i>p</i> < 0.01). The study underscores the need for tailored programs focusing on income, stable pricing, housing, and low-interest loans which are crucial for addressing overcoming urban food insecurity.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"5867354"},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Charcoal on the Quality of Vermicompost Produced With Water Hyacinth and Cow Manure. 木炭对用布袋莲和牛粪生产的蛭石堆肥质量的影响
The Scientific World Journal Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/1086347
Solomon Girmay Berhe, Ali Seid, Berhanu Abraha Tsegay, Shinjiro Sato, Getahun Yemata Lule
{"title":"Effect of Charcoal on the Quality of Vermicompost Produced With Water Hyacinth and Cow Manure.","authors":"Solomon Girmay Berhe, Ali Seid, Berhanu Abraha Tsegay, Shinjiro Sato, Getahun Yemata Lule","doi":"10.1155/tswj/1086347","DOIUrl":"10.1155/tswj/1086347","url":null,"abstract":"<p><p>The significance of water hyacinth (<i>Pontederia crassipes</i> (C. Mart.) Solms (Pontederiaceae) vermicomposting lies in its ability to effectively manage its invasiveness while also improving soil fertility and supporting sustainable agricultural practices. This study evaluates the effects of charcoal addition on the composting followed by the vermicomposting of water hyacinth (WH) and cow manure, focusing on the growth, reproduction, and survival of <i>Eisenia fetida</i> earthworms and the quality of the resulting vermicompost. The treatments included WH and cow manure (2:1) with 7.5% charcoal (T1), 5% charcoal (T2), and without charcoal (T3). Composting (30 days) followed by vermicomposting (60 days) was conducted in a controlled greenhouse environment. Samples were collected biweekly to analyze temperature, moisture, pH, electrical conductivity, total nitrogen, total available phosphorous, and total potassium contents, vermicompost yield, and earthworm growth parameters throughout the process. Results showed that T1 and T2 significantly improved earthworm weight (8.23-16.0%), number of earthworms (65.0-69.0%), cocoon production (37.0-49.0%), and hatchling count (49.0-77.6%), compared to T3 (control). Also, T1 and T2 increased pH (4.30-5.75%), total nitrogen (53.6-62.5%), total available phosphorus (61.6-117%), and total potassium (47.5-71.3%) and reduced electrical conductivity (9.91%), total organic carbon (17.9-42.1%), carbon: nitrogen ratio (46.5-64.4%), and vermicompost mass (22.0-28.3%) at the end of the vermicomposting period, compared to T3. Moreover, T1 and T2 exhibited significantly higher lettuce seed germination (92.4-93.5%), germination index (76.2-80.4%), shoot elongation (46.0-92.5%), and root elongation (9.00-15.0%), compared to T3. However, in most of the results, there was no significant difference between T1 and T2. This finding suggests that the use of T2 (5.00%) charcoal addition enhances vermicompost quality to optimal maturity and stability.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"1086347"},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal Parasitic Infection: Prevalence and Associated Risk Factors at Delgi Primary Hospital, Northwest Ethiopia. 肠道寄生虫感染:埃塞俄比亚西北部 Delgi 初级医院的流行率和相关风险因素。
The Scientific World Journal Pub Date : 2025-03-21 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/8787678
Tarekegn Addis, Tilahun Yohannes
{"title":"Intestinal Parasitic Infection: Prevalence and Associated Risk Factors at Delgi Primary Hospital, Northwest Ethiopia.","authors":"Tarekegn Addis, Tilahun Yohannes","doi":"10.1155/tswj/8787678","DOIUrl":"10.1155/tswj/8787678","url":null,"abstract":"<p><p>Intestinal parasitic infections (IPIs) are among the leading causes of mortality and morbidity in developing nations such as Ethiopia. Determining epidemiological information of IPI is crucial for effective public health planning and intervention. The present study is aimed at assessing the prevalence and associated risk factors of human IPIs at Delgi Primary Hospital, Central Gondar Zone, Northwest Ethiopia. An institutional-based cross-sectional study was conducted from March to May 2023. A stool specimen was collected from 404 selected participants and examined microscopically for the presence of developmental stages of the intestinal parasites. A structured questionnaire was used to obtain information regarding the sociodemographic and associated risk factors. Data were analyzed using SPSS Version 23, and a crude odd ratio was calculated to verify and measure the possible association between IPIs and potential risk factors. A <i>p</i> value < 0.05 was taken as statistically significant. The overall prevalence of IPIs was 47.20%. Six species of intestinal parasites were identified: <i>Entamoeba histolytica/dispar</i> (16.8%) was the most predominant parasite, followed by <i>Giardia lamblia</i> (9.9%), <i>Ascaris lumbricoides</i> (8.1%), Hookworm species (7.6%), <i>Schistosoma mansoni</i> (4.2%), and <i>Hymenolepis nana</i> (0.5%). Furthermore, double and triple parasitic infections were observed in 10.39% and 0.49% of the study participants, respectively. Not having a habit of handwashing after toilet (AOR = 2.048, CI = 0.694, 3.583, <i>p</i> = 0.001), the habit of eating unwashed vegetables (<i>AOR</i> = 3.046, <i>CI</i> = 0.685, 5.596, <i>p</i> = 0.016), and presence of dirt matter under the nail (<i>AOR</i> = 2.939, <i>CI</i> = 0.621, 4.418, <i>p</i> = 0.001) were found to be significantly associated risk factors. This study showed that IPIs remained a public health concern in the study area. Therefore, regular provision of health education on personal hygiene and sanitation is recommended to prevent and control IPIs in the study area.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"8787678"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydroethanolic Extract of Salvia officinalis L. Leaves Improves Memory and Alleviates Neuroinflammation in ICR Mice. 鼠尾草叶氢乙醇提取物改善ICR小鼠记忆和神经炎症。
The Scientific World Journal Pub Date : 2025-03-20 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/2198542
Bernard Sefah, Yolanda Ashie, Newman Osafo, Priscilla Kolibea Mante
{"title":"Hydroethanolic Extract of <i>Salvia officinalis</i> L. Leaves Improves Memory and Alleviates Neuroinflammation in ICR Mice.","authors":"Bernard Sefah, Yolanda Ashie, Newman Osafo, Priscilla Kolibea Mante","doi":"10.1155/tswj/2198542","DOIUrl":"10.1155/tswj/2198542","url":null,"abstract":"<p><p>Neurodegenerative disorders are known to be commonly associated with neuroinflammation. Plants with antioxidant and anti-inflammatory properties hold prospect in alleviating neuroinflammation. One such plant with documented anti-inflammatory and antioxidant potential is <i>Salvia officinalis</i> L. This study looked at effects of the hydroethanolic leaf extract of <i>S. officinalis</i> L. on lipopolysaccharide (LPS)-induced neuroinflammation and associated memory impairment using an ICR mouse model. Assessment of the phytochemical constituents in <i>S. officinalis</i> L. and its acute toxicity was conducted. Mice were treated with <i>S. officinalis</i> L. extract (30, 100, and 300 mg/kg) after LPS administration. Object recognition and elevated plus maze tests were employed to assess neuroinflammation-induced behavioral changes. Brain samples were taken to determine the levels of TNF-<i>α</i> and conduct histopathological analysis. The hydroethanolic extract of <i>S. officinalis</i> L. was found to contain alkaloids, glycoside, tannins, flavonoids, and coumarins and exhibited no observable acute toxicity. The extract showed the presence of eicosatrienoic acid, methyl ester, and phenanthrene derivatives. The extract improved memory and cognitive performance but had no significant effect on brain tissue TNF-<i>α</i> expression. <i>S. officinalis</i> L. treatment in mice with neuroinflammation also resulted in reduced mononuclear infiltration and gliosis and reduced apoptotic and necrotic neurons as well as no observable brain lesions. <i>S. officinalis</i> L. holds promising pharmacological activity at reducing neuroinflammation and its associated cognitive impairment.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"2198542"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Compliance: The Role of Self-Efficacy in Foot Care and Self-Management Among Patients With Type 1 Diabetes. 超越遵从:自我效能在 1 型糖尿病患者足部护理和自我管理中的作用。
The Scientific World Journal Pub Date : 2025-03-18 eCollection Date: 2025-01-01 DOI: 10.1155/tswj/8848211
Mohamad Amir Sadeghi, Afsaneh Raiesifar, Sanaz Aazami
{"title":"Beyond Compliance: The Role of Self-Efficacy in Foot Care and Self-Management Among Patients With Type 1 Diabetes.","authors":"Mohamad Amir Sadeghi, Afsaneh Raiesifar, Sanaz Aazami","doi":"10.1155/tswj/8848211","DOIUrl":"10.1155/tswj/8848211","url":null,"abstract":"<p><p><b>Background:</b> Effective self-management behaviors are crucial for diabetes management. This study examines the mediating role of self-efficacy in the relationship between compliance dimensions and self-management activities in patients with Type 1 diabetes. <b>Methods:</b> The current study explores a baseline analysis from a randomized controlled trial but the intervention's effectiveness is not reported here; the analysis focuses on elucidating potential mediating factors at baseline. The study investigated the relationships between seven compliance dimensions (treatment effort, intention, adaptability, integration, adherence, commitment, and indecisiveness) and six self-management activities (diet, exercise, smoking cessation, blood sugar monitoring, and foot care) through the potential mechanism of self-efficacy. <b>Results:</b> The analysis revealed an indirect association between three compliance dimensions (treatment effort, intention, and commitment) and foot care behavior, mediated by self-efficacy. Additionally, self-efficacy was identified as an indirect mechanism influencing the association between commitment and adaptability with dietary behaviors. <b>Conclusions:</b> This study highlights the importance of self-efficacy in promoting self-management behaviors in chronic conditions. By targeting specific compliance dimensions that influence self-efficacy, healthcare professionals can potentially improve patient self-management. <b>Trial Registration:</b> Iranian Registry of Clinical Trials number: IRCT20221029056335N1.</p>","PeriodicalId":22985,"journal":{"name":"The Scientific World Journal","volume":"2025 ","pages":"8848211"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信