{"title":"Projection of future demand for non-cancerous gastrointestinal surgery in Japan: challenges and workforce planning in an aging society.","authors":"Masakazu Fujii, Toru Nakamura, Yasuyuki Okumura, Yoichi M Ito, Toshimichi Asano, Satoshi Hirano","doi":"10.1007/s00595-025-03027-9","DOIUrl":"10.1007/s00595-025-03027-9","url":null,"abstract":"<p><strong>Purpose: </strong>Japan's aging population poses challenges for balancing healthcare demands and workforce supply. The aim of this study was to project the future demand for major non-cancerous gastrointestinal surgeries such as cholecystectomy, inguinal hernia repair, and appendectomy up until 2050 and examine the impact of a shrinking working-age population on surgical workforce needs.</p><p><strong>Methods: </strong>We used data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan Open Data (2018-2022) and population projections to calculate age- and sex-specific procedure rates. These rates were applied to population forecasts for 2030, 2040, and 2050 under high, low, and average demand scenarios. Working-age population (15-65 years) trends were included for comparison.</p><p><strong>Results: </strong>The projected demand for appendectomy, most common in people aged 20-39, is expected to decrease by 16.6% by 2050, whereas cholecystectomy and inguinal hernia repair demand, concentrated in people aged 60 and above, are projected to decrease by 5.8% and 7.1%, respectively. The working-age population is anticipated to decline by 25.3%, potentially posing significant challenges to maintaining an adequate surgical workforce.</p><p><strong>Conclusions: </strong>While the absolute number of gastrointestinal surgeries is projected to decrease, Japan faces substantial demographic changes that may impact surgical workforce capacity. Strategic workforce planning is essential to address these demographic challenges.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1262-1268"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of social media on the career choices of medical students and junior residents in Japan: a prospective study to strategize an increase in the number of aspiring surgeons.","authors":"Naoya Kitamura, Naru Kitade, Ryo Yokoyama, Toshihiro Ojima, Koichiro Shimoyama, Keitaro Tanabe, Yoshifumi Shimada, Yushi Akemoto, Yoshinori Doki, Tomoshi Tsuchiya","doi":"10.1007/s00595-025-03023-z","DOIUrl":"10.1007/s00595-025-03023-z","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the most effective use of social media to increase the number of aspiring surgeons, we evaluated the impact of social media on the career choices of medical students and junior residents.</p><p><strong>Methods: </strong>We conducted a single-center prospective observational questionnaire-based study on medical students and junior residents from March, 2023 to August, 2024. Following overall aggregation, statistical intergroup comparisons were made between students and junior residents, as well as between those who were, or were not influenced by social media.</p><p><strong>Results: </strong>Among the 101 participants (77 students, 24 junior residents), approximately 75% reported that social media influenced their career choices. The most frequently used platforms were YouTube (85.1%), Instagram (71.3%), and X (67.3%). A total of 46.5% of the respondents expressed an interest in surgical specialties. Junior residents were more likely than students to gather information related to medicine (p = 0.0442). The group influenced by social media showed a higher interest in surgical specialties (p = 0.0475), and many desired parental leave policies to increase the number of surgeons (p = 0.0376).</p><p><strong>Conclusion: </strong>Social media influences the career choices of medical students and junior residents, and its effective use could increase the number of aspiring surgeons.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1252-1261"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Motivations and factors influencing the choice of a career as a thoracic surgeon in Japan: results of a nationwide questionnaire survey.","authors":"Takahiro Homma, Ryota Tanaka, Shota Nakamura, Masato Aragaki, Toyofumi Fengshi Chen-Yoshikawa, Tatsuya Kato, Hisahi Saji","doi":"10.1007/s00595-025-03111-0","DOIUrl":"https://doi.org/10.1007/s00595-025-03111-0","url":null,"abstract":"<p><strong>Purpose: </strong>Addressing the decline in the number of surgeons in Japan and an uneven specialty distribution is crucial for a sustainable working environment. We conducted this study to investigate the motivations behind the choice of medical specialty among thoracic surgeons across multiple institutions in Japan.</p><p><strong>Methods: </strong>A nationwide online questionnaire survey was distributed by the Japanese Association for Surgical Education's thoracic surgery working group, targeting all thoracic surgeons.</p><p><strong>Results: </strong>Of the 725 respondents, 95.6% decided on thoracic surgery after starting clinical training. The key influencing factors included respectful supervisors and seniors (79.3%), procedures (78.1%), organs (77.9%), diseases (75.4%), and atmosphere (70.3%). The final deciding factors were procedures (37.1%), atmosphere (17.0%), and organs (11.2%), with work-life balance reported by 7.0%. More thoracic surgeons in the 20 s-30 s age group than those in the over 40 s age group prioritized procedures (47.3% vs 31.5%; P < 0.0001), organs (14.3% vs 9.4%; P = 0.049), and work-life balance (11.2% vs 4.7%; P = 0.0014). Only 9.2% of respondents chose a career in thoracic surgery exclusively, whereas 90.8% considered other specialties (81.3% surgical, 18.7% non-surgical).</p><p><strong>Conclusion: </strong>This survey revealed that the broad appeal of thoracic surgery often attracted individuals from diverse backgrounds, sometimes after they had considered other specialties. Increasing the number of thoracic surgeons requires promoting its appeal and fostering a positive work and educational environment.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward equitable parenting in surgery: a response to commentary on the \"Daddy Surgeon\" case study.","authors":"Nobuhiko Kanaya, Shinji Kuroda, Yoshitaka Kondo, Yuko Takehara, Toshiyoshi Fujiwara","doi":"10.1007/s00595-025-03115-w","DOIUrl":"https://doi.org/10.1007/s00595-025-03115-w","url":null,"abstract":"","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of a reinforced triple-row stapler with a powered stapling system reduces the occurrence of postoperative pancreatic fistula after distal pancreatectomy.","authors":"Shinjiro Kobayashi, Keisuke Ida, Saori Umezawa, Kazunari Nakahara, Keisuke Tateishi, Tomoko Norose, Nobuyuki Ohike, Tsuyoshi Morimoto, Shinya Mikami, Takehito Otsubo","doi":"10.1007/s00595-025-03123-w","DOIUrl":"https://doi.org/10.1007/s00595-025-03123-w","url":null,"abstract":"<p><strong>Purpose: </strong>Stapled closure is the standard technique for pancreatic resection via distal pancreatectomy (DP). The Signia™ Stapling System allows for adaptive stapling based on real-time tissue resistance. This study aims to investigate whether DP using the Signia™ system could reduce the incidence of clinically relevant post-operative pancreatic fistula (CR-POPF).</p><p><strong>Methods: </strong>We retrospectively analyzed 53 patients who underwent DP between 2020 and 2025. 26 patients underwent DP using the Signia™ Stapling System (powered stapler group), and 27 patients using a manual stapler (manual stapler group). The primary outcome was the CR-POPF rate.</p><p><strong>Results: </strong>In the powered stapler group, 38.5% of patients developed biochemical leakage, but no cases of CR-POPF were observed. In contrast, the manual stapler group had a CR-POPF rate of 18.5% (p = 0.021). A receiver operating characteristic curve was generated to determine the pancreatic thickness threshold predictive of CR-POPF. The calculated cut-off value was 16 mm. In the powered group, there were no cases of CR-POPF even if the pancreatic thickness at the resection line was ≥ 16 mm.</p><p><strong>Conclusions: </strong>The use of a powered stapler may therefore help reduce the risk of POPF associated with variability in the thickness and hardness of the pancreas during DP.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative chemotherapy with a modified docetaxel, cisplatin, and S-1 regimen, followed by gastrectomy and lymphadenectomy for gastric cancer with bulky lymph nodes.","authors":"Vo Duy Long, Dang Quang Thong, Tran Quang Dat, Doan Thuy Nguyen, Tran Vinh Tho, Tran Duy Phuoc, Nguyen Viet Hai, Nguyen Lam Vuong, Lam Quoc Trung, Nguyen Hoang Bac","doi":"10.1007/s00595-025-03114-x","DOIUrl":"https://doi.org/10.1007/s00595-025-03114-x","url":null,"abstract":"<p><strong>Purpose: </strong>The appropriate regimen and dosage of preoperative chemotherapy for gastric cancer (GC) with bulky lymph nodes (LNs) remain controversial. We conducted this study to evaluate the efficacy of preoperative chemotherapy using a modified regimen of docetaxel, cisplatin, and S-1 (DCS) for GC with bulky LNs, assessing feasibility, toxicity, response rate, and oncological outcomes.</p><p><strong>Methods: </strong>Thirty-two patients who had GC with bulky LNs diagnosed between Jan, 2018 and Oct, 2022 received three or four cycles of modified DCS regimen preoperatively. The primary outcome was 3 year overall survival (OS).</p><p><strong>Results: </strong>The completion rate of preoperative chemotherapy was 90.6% (4 cycles: 50.0%, 3 cycles: 40.6%). The disease control rate (DCR) and clinical response rate (RR) were 87.5% and 81.3%, respectively. Grade-3/4 neutropenia and anemia developed in 6.2% and 9.4%, respectively. Twenty-two patients with partial response (PR) agreed to undergo gastrectomy and LN dissection. Pathologic complete response (CR) was achieved in 15.6%. After surgery, there were no grade > = 3 postoperative complications. The R0-resection rate was 65.6%. The 3 year OS and progression-free survival (PFS) rates were 43.0% and 37%, respectively, for all eligible patients. The 3 year OS and PFS of patients in the surgery group with negative para-aortic LNs were 58% and 47.0%, respectively.</p><p><strong>Conclusion: </strong>Preoperative chemotherapy with a modified DCS regimen demonstrated high tolerance, a clinical response rate, and satisfactory 3 year survival outcomes. Thus, a preoperative modified DCS regimen with 3-4 cycles is a promising approach for GC with bulky LNs.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low preoperative prealbumin increases non-gastric cancer mortality in patients with early or advanced gastric cancer after gastrectomy: a retrospective cohort study.","authors":"Ryota Matsui, Souya Nunobe, Motonari Ri, Rie Makuuchi, Tomoyuki Irino, Masaru Hayami, Manabu Ohashi, Takeshi Sano","doi":"10.1007/s00595-025-03112-z","DOIUrl":"https://doi.org/10.1007/s00595-025-03112-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the relationship between preoperative prealbumin levels and long-term outcomes in patients with advanced gastric cancer after gastrectomy.</p><p><strong>Methods: </strong>This study included patients who underwent radical gastrectomy for primary stage I-III gastric cancer with preoperative prealbumin levels measured from May 2006 to March 2017. The patients were categorized into 3 groups based on their preoperative prealbumin levels: high (≥ 22 mg/dL), moderate (15-22 mg/dL), and low (< 15 mg/dL).</p><p><strong>Results: </strong>Of the 3,050 pStage I patients, 2488 (81.6%) were classified as high, 511 (16.8%) as moderate, and 51 (1.7%) as low. Of the 1682 patients with pStage II-III, 1161 (69.0%) were classified as high, 414 (24.6%) as moderate, and 107 (6.4%) as low. A comparison of the overall survival (OS) revealed that lower prealbumin levels were associated with a worse prognosis (P < 0.001). A multivariate analysis indicated that prealbumin levels of 15-22 mg/dL and < 15 mg/dL were independent poor prognostic factors for the OS, regardless of the pStage. When stratified by cause of death, prealbumin levels were associated with the other-cause survival but not the cancer-specific survival.</p><p><strong>Conclusions: </strong>Preoperative prealbumin levels were correlated with the OS, especially the other-cause survival, in patients with gastric cancer after gastrectomy. (200 words). Data Access Statement: Research data supporting this publication are available from the NN repository at located at www.NNN.org/download/ .</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical outcomes of completion lobectomy after primary segmentectomy.","authors":"Aritoshi Hattori, Takeshi Matsunaga, Mariko Fukui, Hisashi Tomita, Kazuya Takamochi, Kenji Suzuki","doi":"10.1007/s00595-025-03122-x","DOIUrl":"https://doi.org/10.1007/s00595-025-03122-x","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated the surgical outcomes of completion lobectomy after primary segmentectomy for lung malignancies.</p><p><strong>Methods: </strong>A review of 1139 patients who underwent pulmonary segmentectomy for lung malignancies, identified 17 (1.5%) who underwent completion lobectomy. We analyzed the clinicopathological outcomes of completion lobectomy in these 17 patients, statistically, and evaluated the degree of surgical difficulty, using logistic regression models.</p><p><strong>Results: </strong>The primary segmentectomy was performed on the right-side in six patients, centrally in seven, in the upper lobe in nine, and as a complex segmentectomy in ten. Lung cancer was diagnosed in 13 patients. Completion lobectomy required an intrapericardial procedure in five patients, main pulmonary artery (PA) clamping in seven, bronchial plasty in five, and PA-plasty in five. The mean operative time was 219 min, and the mean blood loss was 193 ml. Cut-end recurrence was confirmed in nine (56%) patients, and Grade III or higher morbidity occurred in six patients (38%) with no short-term mortality. Logistic regression analysis revealed that upper lobe completion lobectomy was a significant predictor of surgical difficulty (OR 23.8, 95%CI 1.742-333.3, p = 0.018).</p><p><strong>Conclusion: </strong>Completion lobectomy is technically challenging, especially in the upper lobe, but the oncological and surgical results are acceptable. This procedure is a promising and important strategy for treating secondary lesions in the residual lobe after segmentectomy.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-08-23DOI: 10.1007/s00595-025-03120-z
Takuya Shiraishi, Ikuma Shioi, Chika Katayama, Yuta Shibasaki, Chika Komine, Katsuya Osone, Takuhisa Okada, Hiroomi Ogawa, Ken Shirabe, Hiroshi Saeki
{"title":"Comparison of the postoperative outcomes between the robotic transabdominal approach alone and the combined robotic transabdominal and conventional transanal approach for rectal cancer.","authors":"Takuya Shiraishi, Ikuma Shioi, Chika Katayama, Yuta Shibasaki, Chika Komine, Katsuya Osone, Takuhisa Okada, Hiroomi Ogawa, Ken Shirabe, Hiroshi Saeki","doi":"10.1007/s00595-025-03120-z","DOIUrl":"https://doi.org/10.1007/s00595-025-03120-z","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to compare the safety, feasibility, required human resources, and surgical costs of a combined robotic transabdominal and conventional transanal (TaRob) approach with those of a robotic transabdominal approach alone for rectal cancer.</p><p><strong>Methods: </strong>Forty-nine patients who underwent robotic surgery for rectal cancer were retrospectively enrolled and categorized into two groups: robotic transabdominal approach alone (Rob-alone, n = 29) and TaRob approach (TaRob, n = 20). Patient characteristics, short-term postoperative outcomes, human resources, and surgical costs were compared between the groups.</p><p><strong>Results: </strong>The tumor distance from the anal verge was shorter and preoperative treatment was performed more frequently in the TaRob group. The total operation time was shorter in the TaRob group (258 vs. 325 min), with no between-group differences in postoperative complications or pathological outcomes. Although the TaRob group required more staff than the Robot-alone group, the staff time consumed did not differ. The TaRob group had higher surgical costs for consumables than the robot alone group. These results were consistent before and after performing propensity score matching.</p><p><strong>Conclusions: </strong>The combined approach after preoperative treatment for low rectal cancer resulted in a reduced operation time without any increased postoperative complications. The combined approach increased surgical costs, but could potentially reduce staff work hours, provided that sufficient staff is available.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-08-23DOI: 10.1007/s00595-025-03118-7
Akihisa Matsuda, Takeshi Yamada, Kay Uehara, Seiichi Shinji, Yasuyuki Yokoyama, Goro Takahashi, Takuma Iwai, Toshimitsu Miyasaka, Shintaro Kanaka, Takanori Matsui, Koki Hayashi, Hiroshi Yoshida
{"title":"Comparison between barbed and non-barbed sutures for fascial closure in abdominal surgery: a systematic review and meta-analysis.","authors":"Akihisa Matsuda, Takeshi Yamada, Kay Uehara, Seiichi Shinji, Yasuyuki Yokoyama, Goro Takahashi, Takuma Iwai, Toshimitsu Miyasaka, Shintaro Kanaka, Takanori Matsui, Koki Hayashi, Hiroshi Yoshida","doi":"10.1007/s00595-025-03118-7","DOIUrl":"https://doi.org/10.1007/s00595-025-03118-7","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the safety and efficacy of barbed and non-barbed sutures for fascial closure in abdominal surgery.</p><p><strong>Methods: </strong>A systematic literature search through February 2025 identified studies comparing overall surgical site infections (SSI), fascial complications, and hospital stays between barbed and non-barbed sutures. A meta-analysis using random-effects models calculated odds ratios (ORs) or mean differences (MDs) with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Seven studies involving 12,278 patients (barbed group, n = 4912; non-barbed group, n = 7366) were included. The overall SSI rates were 1.9% and 4.0% in the barbed and non-barbed groups, respectively. Barbed sutures significantly reduced overall SSIs (OR, 0.41; 95% CI: 0.31-0.53; P < 0.001) without statistical heterogeneity. Barbed suture also significantly reduced the length of hospital stay (MD, - 1.13; 95% CI: - 1.42- - 0.83, P < 0.001) without statistical heterogeneity. No significant difference was observed in fascial complications between the groups (OR, 0.66; 95% CI: 0.36-1.22, P = 0.19).</p><p><strong>Conclusions: </strong>This is the first meta-analysis to focus specifically on barbed sutures for abdominal fascial closure. Barbed sutures significantly reduce SSI and hospital stay without increasing fascial complications, thus suggesting that they are safe and efficient options for abdominal wall closure.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144970032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}