{"title":"Evaluating the relevant factors affecting the perioperative outcomes of laparoscopic fundoplication in 100 neurologically impaired patients: a multicenter retrospective joint study.","authors":"Yoshinori Koga, Koshiro Sugita, Naoki Hashizume, Daisuke Masui, Kazuhiko Nakame, Shun Onishi, Motofumi Torikai, Satoshi Ieiri, Tatsuru Kaji","doi":"10.1007/s00595-025-03067-1","DOIUrl":"https://doi.org/10.1007/s00595-025-03067-1","url":null,"abstract":"<p><strong>Background: </strong>Postural features (e.g. scoliosis) make laparoscopic fundoplication more difficult in neurologically impaired patients (NIPs) than in non-NIPs [please check this carefully]. We therefore clarified the relevant factors associated with perioperative outcomes of NIPs.</p><p><strong>Methods: </strong>NIPs who underwent laparoscopic Nissen fundoplication were enrolled. We classified the patients according to age into < 18- and ≥ 18-year-old groups and evaluated the factors associated with perioperative outcomes. The endpoints were patient characteristics, acid-reflux index, operative time, blood loss, postoperative outcomes, and Endoscopic Surgical Skill Qualification System (ESSQS) certification.</p><p><strong>Results: </strong>One hundred and one patients underwent laparoscopic fundoplication. Blood loss and operative time were significantly higher in the ≥ 18-year-old group than in the < 18-year-old group. A multivariate regression analysis revealed that no factors were significantly associated with blood loss. However, a significant association was observed between the procedure performed by the ESSQS-certified pediatric surgeon and the operative time. In terms of postoperative outcomes, the length of hospital stay after operations performed or supervised by ESSQS-certified pediatric surgeons was significantly shorter than that after operations performed by pediatric surgeons without ESSQS certification.</p><p><strong>Conclusion: </strong>The involvement of pediatric surgeons with ESSQS certification was significantly associated with perioperative outcomes in NIPs during laparoscopic fundoplication, whereas physical characteristics and GER were not.</p><p><strong>Levels of evidence: </strong>Level III, case-control study.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PD-L1 expression correlates with the oncological severity and prognosis of early-stage lung cancer.","authors":"Ken Onodera, Hirotsugu Notsuda, Sakiko Kumata, Tatsuaki Watanabe, Yui Watanabe, Takaya Suzuki, Takashi Hirama, Hisashi Oishi, Yoshinori Okada","doi":"10.1007/s00595-025-03070-6","DOIUrl":"https://doi.org/10.1007/s00595-025-03070-6","url":null,"abstract":"<p><strong>Purpose: </strong>The expression of PD-L1 is linked to lung cancer severity; however, its prognostic value after resection is unclear. In this study, we investigated its role in resected lung cancers.</p><p><strong>Methods: </strong>We analyzed 658 patients with stage pIA-IIIA NSCLC who underwent complete resection. We assessed the PD-L1 expression by stage and its link to cancer severity, focusing further on its prognostic impact in resected stage I cell lung cancer.</p><p><strong>Results: </strong>The high expression of PD-L1 increased with disease progression (13.0% in IA to 36.2% in III). In stage I non-small cell lung cancer, elevated PD-L1 expression levels were more common in patients with serum CEA levels ≥ 5 (26.0%), SUVmax ≥ 5 (26.7%), and squamous cell carcinoma (41.5%). PD-L1-negative patients showed a better prognosis than PD-L1-positive patients, even with the use of immune checkpoint inhibitors following relapse (5-year OS: 94.3% vs. 83.2%, p < 0.01).</p><p><strong>Conclusion: </strong>The expression of PD-L1 in lung cancer appears to be associated with oncological severity and may influence the prognosis of early-stage disease. Additionally, in early-stage lung cancer, immune checkpoint inhibitors may not fully compensate for the negative prognostic impact of the high expression of PD-L1.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the short-term outcome of laparoscopic pelvic exenteration in locally advanced and recurrent rectal cancer.","authors":"Kosuke Ozaki, Toshiki Mukai, Yohei Ando, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Tomohiro Yamaguchi, Takashi Akiyoshi","doi":"10.1007/s00595-025-03048-4","DOIUrl":"https://doi.org/10.1007/s00595-025-03048-4","url":null,"abstract":"<p><strong>Purpose: </strong>Pelvic exenteration (PE) is sometimes the only curative option for primary rectal cancer as well as locally recurrent rectal cancer (LRRC). However, data on laparoscopic PE (Lap-PE) for LRRC are limited. This study aimed to evaluate the technical safety of Lap-PE in LRRC cases.</p><p><strong>Methods: </strong>We retrospectively analyzed 63 patients who underwent Lap-PE between January 2013 and December 2023. Patients were categorized into primary (n = 41) and recurrent (n = 22) groups, and short-term outcomes, including operative details and postoperative complications, were compared.</p><p><strong>Results: </strong>The recurrent group had a significantly higher number of cases of multiple organs resected beyond PE (24.4% vs. 63.6%, p = 0.001). There were no significant differences in the operative time (714 vs. 633 min, p = 0.91) or blood loss (650 vs. 580 g, p = 0.98) between the groups. Clavien-Dindo Grade 3 complications occurred in 29.3% of primary cases and 18.2% of recurrent cases (p = 0.47). R0 resection was achieved in 95.1% of primary cases and 81.8% of recurrent cases (p = 0.10).</p><p><strong>Conclusion: </strong>Lap PE for LRRC, when performed by an experienced laparoscopic surgical team with careful patient selection, was shown to be safe, with comparable short-term outcomes to those of PE for primary rectal cancer and an acceptable R0 resection rate.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Virtual thoracoscopic imaging for accurate pulmonary nodule localization: clinical experience.","authors":"Yuka Kadomatsu, Megumi Nakao, Shoji Okado, Harushi Ueno, Taketo Kato, Shota Nakamura, Toyofumi Fengshi Chen-Yoshikawa","doi":"10.1007/s00595-024-02945-4","DOIUrl":"10.1007/s00595-024-02945-4","url":null,"abstract":"<p><p>The increasing detection of small pulmonary nodules on computed tomography (CT) warrants simple and effective nodule localization methods. We describe our clinical experience using an experimental computer that displays virtual thoracoscopic images. This device constructs three-dimensional images from preoperative CT scans and simulates the deflated lung parenchyma in the lateral decubitus position. Five patients underwent lung resection using this technology. The device provided images that closely resembled actual thoracoscopic images in all cases. This method addresses the limitations of other localization techniques such as allergic reactions and mechanical marker-related complications. The method only requires preoperative CT images, and the process is semi-automatically performed by specifying the nodule location, thoracoscopic camera insertion site, and camera angle. This study is still in the preliminary phase and has several limitations. However, this method has the potential to accurately predict nodule locations and eliminate the many risks associated with other techniques.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"860-864"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-06-01Epub Date: 2025-02-10DOI: 10.1007/s00595-025-03008-y
Miho Akabane, Yuki Imaoka, Toshihiro Nakayama, Carlos O Esquivel, Kazunari Sasaki
{"title":"Effect of sarcopenia on the survival of patients undergoing liver transplantation: a meta-analysis.","authors":"Miho Akabane, Yuki Imaoka, Toshihiro Nakayama, Carlos O Esquivel, Kazunari Sasaki","doi":"10.1007/s00595-025-03008-y","DOIUrl":"10.1007/s00595-025-03008-y","url":null,"abstract":"<p><strong>Purpose: </strong>The relationship between sarcopenia and post-liver transplant (LT) mortality is still not well understood. This study aims to provide an updated and comprehensive meta-analysis evaluating the impact of sarcopenia on the survival of LT patients.</p><p><strong>Methods: </strong>We conducted searches in PubMed, Web of Science, and EMBASE up until May 2, 2024, without language restrictions. The primary outcome measured was the overall post-LT mortality risk associated with sarcopenia. The DerSimonian-Laird random effects model was used to calculate pooled adjusted hazard ratios (HRs).</p><p><strong>Results: </strong>Eighteen cohort studies comprising a total 6297 LT patients were included. The overall prevalence of sarcopenia was 27% (95% CI: 26%-28%), and this rate was lower when sarcopenia was defined using the third lumbar-skeletal muscle index in men, and among patients with lower Child-Pugh class. Sarcopenia remained significantly associated with higher mortality, with a pooled adjusted HR of 1.55 (95% CI 1.28-1.89). This association held across subgroups based on sex, study location, sarcopenia definition, study quality, and living donor LT recipients. A sensitivity analysis excluding groups with a high proportion of hepatocellular carcinoma patients showed similar findings (HR 1.63, 95% CI 1.13-2.35). No significant heterogeneity was identified in any of the analyses.</p><p><strong>Conclusions: </strong>This meta-analysis shows that sarcopenia is significantly associated with increased mortality after LT. Thus, the risk of sarcopenia should be factored into the initial evaluation of LT candidates.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"803-813"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-06-01Epub Date: 2025-04-26DOI: 10.1007/s00595-025-03049-3
Seijiro Sato, Saeko Nakayama, Hirohiko Shinohara
{"title":"Preoperative myosteatosis as a novel prognostic biomarker after anatomical lung resection for non-small cell lung cancer.","authors":"Seijiro Sato, Saeko Nakayama, Hirohiko Shinohara","doi":"10.1007/s00595-025-03049-3","DOIUrl":"10.1007/s00595-025-03049-3","url":null,"abstract":"<p><strong>Purpose: </strong>Myosteatosis, or excessive deposition of adipose tissue within skeletal muscle, has been widely used to explain an impaired muscle quality. This study aimed to investigate the association between preoperative myosteatosis and surgical outcomes in patients with non-small-cell lung cancer (NSCLC).</p><p><strong>Methods: </strong>We retrospectively examined 492 patients who underwent anatomical lung resection for stages I-III NSCLC between January 2014 and December 2022. The patients were divided into low- and high-paraspinal muscle density (MD) groups based on the lowest quartile cutoff value of MD on contrast-enhanced computed tomography, with the low-MD group defined as having myosteatosis.</p><p><strong>Results: </strong>The five-year overall survival (OS) and recurrence-free survival (RFS) rates were significantly lower in the myosteatosis group than in the control group (59.1% vs. 86.8%, P < 0.001; 52.0% vs. 72.6%, P < 0.001, respectively). A multivariate analysis identified myosteatosis as an independent predictor of OS (hazard ratio [HR], 2.809; 95% confidence interval [CI], 1.781-4.430; P < 0.001) and RFS (HR, 1.894; 95%CI, 1.340-2.678; P < 0.001). There was a significant correlation between myosteatosis and prolonged air leak postoperatively (P = 0.039).</p><p><strong>Conclusion: </strong>Perioperative nutritional and exercise interventions facilitate changes in body composition, which may improve the outcomes in patients with lung cancer undergoing anatomical resection.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"727-738"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-06-01Epub Date: 2024-11-08DOI: 10.1007/s00595-024-02953-4
Tatsuya Suzuki, Hayato Konishi, Akiyo Suzuki, Takahiro Katsumata, Yasuhiro Fukuda, Koki Miyamoto, Tomokazu Ise, Yukiko Tanaka, Aki Yamamoto, Panyue Wen, Shohei Shiomoto, Masaru Tanaka, Shintaro Nemoto
{"title":"Role of intermediate water in alleviating postsurgical intrapericardial adhesion.","authors":"Tatsuya Suzuki, Hayato Konishi, Akiyo Suzuki, Takahiro Katsumata, Yasuhiro Fukuda, Koki Miyamoto, Tomokazu Ise, Yukiko Tanaka, Aki Yamamoto, Panyue Wen, Shohei Shiomoto, Masaru Tanaka, Shintaro Nemoto","doi":"10.1007/s00595-024-02953-4","DOIUrl":"10.1007/s00595-024-02953-4","url":null,"abstract":"<p><strong>Purpose: </strong>Various polymers have been used as postsurgical antiadhesive materials; however, the mechanisms underlying their efficacy remain unclear. Intermediate water has been found to prevent the adhesion between polymer molecules and proteins or cells. The present study investigated the role of intermediate water retained in the polymer in alleviating postsurgical pericardial adhesion.</p><p><strong>Methods: </strong>Hydrophobic fabrics were prepared using biodegradable polyglycolic acid. To add intermediate water, the fabric fibers were coated with poly(oxyethylene)oleyl ethers. Intermediate water in the hydrated state was detected by a thermal analysis for each material, and cell attachment to the fibers with or without coating was observed in vitro. Using a canine model of postsurgical pericardial adhesion, the severity of adhesion was examined along with a histological assessment during treatment, with or without fabric coating.</p><p><strong>Results: </strong>Intermediate water was detected in the coating materials but not in polyglycolic acid. Coating significantly reduced the cell attachment to the fibers. Coating also alleviated adhesion by reducing inflammation in the fibrous layer and replacing the fabric and granulomas that develop around the surgical sutures in the pericardial space.</p><p><strong>Conclusions: </strong>Intermediate water in the hydrated polymer of anti-adhesives may play an important role in alleviating postoperative pericardial adhesion.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"847-856"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-06-01Epub Date: 2025-02-28DOI: 10.1007/s00595-025-03016-y
Takaaki Oba, Kazuma Maeno, Ryoko Iji, Nami Kiyosawa, Yonghan Park, Hiroki Morikawa, Masatsugu Amitani, Tadafumi Shimizu, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Hisanori Matoba, Fumiyoshi Takayama, Ken-Ichi Ito
{"title":"Utility of contrast-enhanced magnetic resonance imaging for planning of surgical procedure in Paget's disease of the breast.","authors":"Takaaki Oba, Kazuma Maeno, Ryoko Iji, Nami Kiyosawa, Yonghan Park, Hiroki Morikawa, Masatsugu Amitani, Tadafumi Shimizu, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Hisanori Matoba, Fumiyoshi Takayama, Ken-Ichi Ito","doi":"10.1007/s00595-025-03016-y","DOIUrl":"10.1007/s00595-025-03016-y","url":null,"abstract":"<p><strong>Purpose: </strong>Contrast-enhanced magnetic resonance imaging (CE-MRI) is an essential imaging modality for planning breast cancer surgical procedures. However, CE-MRI findings in Paget's disease of the breast (PD) have not been studied extensively. This study aimed to elucidate the CE-MRI findings of PD and assess their role in surgical treatment planning.</p><p><strong>Methods: </strong>Twelve patients with PD who underwent surgery between 2011 and 2023 were retrospectively analyzed.</p><p><strong>Results: </strong>The average patient age was 73.8 ± 14.3 years. CE-MRI detected enhanced areas in the nipple-areola complex (NAC) and/or surrounding skin in all patients. Additionally, 6 patients showed enhanced areas within the breast, suggesting ductal spread into the breast. Of these, 1 patient underwent breast-conserving surgery (BCS), and 5 opted for mastectomy. Pathology confirmed the extent of ductal spread of PD, as indicated by CE-MRI. Among the 6 patients who did not have an enhanced area in the breast, 3 underwent BCS or central lumpectomy including NAC, and 3 chose mastectomy based on the patient's preference, and no malignant foci were observed in the breast.</p><p><strong>Conclusion: </strong>CE-MRI effectively evaluated the ductal spread of PD in the breast, demonstrating its utility in guiding the selection of surgical procedures.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"778-786"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visual course of anatomical landmarks around the internal inguinal ring as a guide for horizon adjustment in laparoscopic inguinal hernia repair.","authors":"Kentaro Shinohara, Takuya Saito, Kohei Yasui, Shoko Kato, Sho Ueda, Yasuyuki Fukami, Shunichiro Komatsu, Kenitiro Kaneko, Tsuyoshi Sano","doi":"10.1007/s00595-024-02990-z","DOIUrl":"10.1007/s00595-024-02990-z","url":null,"abstract":"<p><strong>Purpose: </strong>During laparoscopic inguinal hernia repair, the inferior epigastric vessels (IEVs), vas deferens, and spermatic vessels are often used as landmarks for horizon adjustment during camera navigation. The present study investigated the visual angle of landmarks around the internal inguinal ring using recorded video clips.</p><p><strong>Methods: </strong>The angle of the IEVs, vas deferens, spermatic vessels, and the degree of lateral tilt of the scope were measured using a video clip. The angle of the median line of the vas deferens and spermatic vessels (MVS) was also calculated.</p><p><strong>Results: </strong>Between 2018 and 2022, 70 inguinal hernia lesions underwent robot-assisted inguinal hernia repair. Under adjustment according to lateral tilt of the scope, the mean angles of the IEVs and MVS were 14.1° laterally (SD = 15.9°) and -1.5° medially (SD = 15.8°), respectively.</p><p><strong>Conclusion: </strong>The IEVs and MVS do not always adopt an absolutely vertical course, and some structures run obliquely. The angles of the IEVs and MVS should, therefore, be confirmed at the beginning of the operation to guide horizon adjustment.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"739-745"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scoring model for the diagnosis of colorectal perforation and its differentiation from gastroduodenal perforation.","authors":"Toshimichi Kobayashi, Eiji Hidaka, Itsuki Koganezawa, Masashi Nakagawa, Kei Yokozuka, Shigeto Ochiai, Takahiro Gunji, Toru Sano, Yuji Kikuchi, Koichi Tomita, Masatoshi Shigoka, Satoshi Tabuchi, Naokazu Chiba, Shigeyuki Kawachi","doi":"10.1007/s00595-024-02949-0","DOIUrl":"10.1007/s00595-024-02949-0","url":null,"abstract":"<p><strong>Purpose: </strong>Distinguishing colorectal from gastroduodenal perforations is clinically important and challenging. We aimed to establish a scoring model based on objective findings (excluding computed tomography findings) for the diagnosis of colorectal perforation and its differentiation from gastroduodenal perforation.</p><p><strong>Methods: </strong>Patients diagnosed with colorectal or gastroduodenal perforations between January 2014 and December 2021 were retrospectively studied. Univariate and multivariate analyses were performed to identify independent variables, and a scoring model was developed based on these variables.</p><p><strong>Results: </strong>Among 131 eligible patients, 64 (48.9%) were in the colorectal group and 67 (51.1%) were in the gastroduodenal group. White blood cell count, C-reactive protein, and quick Sequential Organ Failure Assessment score were identified as independent clinical variables associated with the diagnosis of colorectal perforation, which differentiated colorectal perforation from gastroduodenal perforation, and were used to develop a new scoring model. The scores ranged from 0 to 5, with an area under the receiver operating characteristic curve of 0.846. The probabilities of colorectal perforation with scores of 0, 1.5, 2, 3, 3.5, and 5 were 3.2, 20, 55.6, 81.8, 73.9, and 82.4%, respectively.</p><p><strong>Conclusion: </strong>The new scoring model may help in treatment selection and perioperative management of patients with gastrointestinal perforation.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"754-759"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}