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Is the use of direct oral anticoagulants after non-cardiac thoracic surgery safe for patients? 非心脏胸外科手术后使用直接口服抗凝剂对患者安全吗?
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-10 DOI: 10.1007/s00595-024-02942-7
Mari Ohkuma, Mariko Fukui, Aritoshi Hattori, Takeshi Matsunaga, Hisashi Tomita, Kazuya Takamochi, Kenji Suzuki
{"title":"Is the use of direct oral anticoagulants after non-cardiac thoracic surgery safe for patients?","authors":"Mari Ohkuma, Mariko Fukui, Aritoshi Hattori, Takeshi Matsunaga, Hisashi Tomita, Kazuya Takamochi, Kenji Suzuki","doi":"10.1007/s00595-024-02942-7","DOIUrl":"https://doi.org/10.1007/s00595-024-02942-7","url":null,"abstract":"<p><strong>Purpose: </strong>The outcomes of direct oral anticoagulant use after noncardiac thoracic surgery have not been elucidated. We compared the safety and efficacy of the postoperative use of direct oral anticoagulants versus warfarin.</p><p><strong>Methods: </strong>This retrospective cohort study included patients taking anticoagulants after noncardiac thoracic surgery between 2008 and 2021. Patients were divided into 2 groups based on drug type: Group D (direct oral anticoagulants) and Group W (warfarin). The occurrence of bleeding and thromboembolic events was also assessed.</p><p><strong>Results: </strong>Anticoagulants were administered to 434 postoperative patients. One (0.4%) of the 247 patients in Group D and 3 (1.6%) of the 187 patients in Group W experienced thromboembolic events. Four patients (1.6%) in Group D and 4 (2.1%) patients in Group W experienced bleeding events. All bleeding events in Group D occurred within 1 week of oral administration, whereas only 1 case of bleeding occurred after resumption in Group W.</p><p><strong>Conclusions: </strong>The outcomes of patients treated with direct oral anticoagulants did not differ from those of patients treated with warfarin. However, major bleeding can occur after the postoperative resumption of direct oral anticoagulant use. Attention should be paid to resuming oral anticoagulants within a few days of non-cardiac thoracic surgery.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anemia rates after one-anastomosis gastric bypass versus sleeve gastrectomy: a retrospective cohort study. 单吻合胃旁路术与袖状胃切除术后的贫血率:一项回顾性队列研究。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-09 DOI: 10.1007/s00595-024-02946-3
Orly Romano-Zelekha, Dean Keren, Yael Herskovitz, Adi Vinograd, Inbal Globus, Lital Keinan-Boker
{"title":"Anemia rates after one-anastomosis gastric bypass versus sleeve gastrectomy: a retrospective cohort study.","authors":"Orly Romano-Zelekha, Dean Keren, Yael Herskovitz, Adi Vinograd, Inbal Globus, Lital Keinan-Boker","doi":"10.1007/s00595-024-02946-3","DOIUrl":"https://doi.org/10.1007/s00595-024-02946-3","url":null,"abstract":"<p><strong>Purpose: </strong>To compare postoperative anemia rates after one-anastomosis gastric bypass (OAGB) with those after sleeve gastrectomy (SG) in a large nationwide, population-based cohort study.</p><p><strong>Methods: </strong>We sourced data from the Israeli Bariatric Surgery Registry. The study included a cohort of adults who underwent bariatric surgery (BS) between 2013 and 2017. Hemoglobin (Hb) was measured preoperatively and then 1 and 2 years post-BS. Anemia rates were compared between the patients who underwent OAGB and those who underwent SG, using multivariable analyses.</p><p><strong>Results: </strong>The study comprised 1,052 patients who underwent OAGB and 5,885 patients who underwent SG. Among them, 24.1% and 23.6% were men, respectively, and the preoperative mean body mass index values were 41.7 ± 5.0 and 42.1 ± 5.1 kg/m2, respectively. The 1-year and 2-year postoperative anemia rates were significantly higher after OAGB than after SG, when adjusted for age, pre-surgery BMI, sex and other covariates (1 year: 37.5% vs. 20.2%; adj-OR = 2.43; 95% CI 2.08-2.86; 2 years: 45.1% vs. 28.5%; adj-OR = 1.92; 95% CI 1.59-2.32).</p><p><strong>Conclusions: </strong>Patients who underwent OAGB had significantly higher anemia rates 1 year and 2 years postoperatively than those who underwent SG. Consequently, vigilant surveillance and intervention strategies post-OAGB should be considered to mitigate the incidence of anemia and its associated complications.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current insights on social media as a tool for the dissemination of research and education in surgery: a narrative review. 关于社交媒体作为外科研究和教育传播工具的当前见解:叙述性综述。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-01 Epub Date: 2024-07-09 DOI: 10.1007/s00595-024-02891-1
Takehito Yamamoto, Kentaro Goto, Shoichi Kitano, Yurina Maeshima, Toshiyuki Yamada, Yoko Azuma, Shintaro Okumura, Naonori Kawakubo, Eiji Tanaka, Kazutaka Obama, Kojiro Taura, Hiroaki Terajima, Tatsuro Tajiri
{"title":"Current insights on social media as a tool for the dissemination of research and education in surgery: a narrative review.","authors":"Takehito Yamamoto, Kentaro Goto, Shoichi Kitano, Yurina Maeshima, Toshiyuki Yamada, Yoko Azuma, Shintaro Okumura, Naonori Kawakubo, Eiji Tanaka, Kazutaka Obama, Kojiro Taura, Hiroaki Terajima, Tatsuro Tajiri","doi":"10.1007/s00595-024-02891-1","DOIUrl":"10.1007/s00595-024-02891-1","url":null,"abstract":"<p><p>The purpose of our narrative review is to summarize the utilization of social media (SoMe) platforms for research communication within the field of surgery. We searched the PubMed database for articles in the last decade that discuss the utilization of SoMe in surgery and then categorized the diverse purposes of SoMe. SoMe proved to be a powerful tool for disseminating articles. Employing strategic methods like visual abstracts enhances article citation rates, the impact factor, h-index, and Altmetric score (an emerging alternative metric that comprehensively and instantly quantifies the social impact of scientific papers). SoMe also proved valuable for surgical education, with online videos shared widely for surgical training. However, it is essential to acknowledge the associated risk of inconsistency in quality. Moreover, SoMe facilitates discussion on specific topics through hashtags or closed groups and is instrumental in recruiting surgeons, with over half of general surgery residency programs in the US efficiently leveraging these platforms to attract the attention of potential candidates. Thus, there is a wealth of evidence supporting the effective use of SoMe for surgeons. In the contemporary era where SoMe is widely utilized, surgeons should be well-versed in this evidence.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141559825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes and pathologic response of primary lung cancer treated with tyrosine kinase inhibitor/immune checkpoint inhibitor before salvage surgery. 抢救性手术前使用酪氨酸激酶抑制剂/免疫检查点抑制剂治疗原发性肺癌的疗效和病理反应。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-01 Epub Date: 2024-03-14 DOI: 10.1007/s00595-024-02811-3
Masaru Takenaka, Fumihiro Tanaka, Kenta Kajiyama, Takehiko Manabe, Katsuma Yoshimatsu, Masataka Mori, Masatoshi Kanayama, Akihiro Taira, Taiji Kuwata, Aya Nawata, Koji Kuroda
{"title":"Outcomes and pathologic response of primary lung cancer treated with tyrosine kinase inhibitor/immune checkpoint inhibitor before salvage surgery.","authors":"Masaru Takenaka, Fumihiro Tanaka, Kenta Kajiyama, Takehiko Manabe, Katsuma Yoshimatsu, Masataka Mori, Masatoshi Kanayama, Akihiro Taira, Taiji Kuwata, Aya Nawata, Koji Kuroda","doi":"10.1007/s00595-024-02811-3","DOIUrl":"10.1007/s00595-024-02811-3","url":null,"abstract":"<p><strong>Purpose: </strong>Advances in primary lung cancer drug therapy have extended patients' survival, including patients with stage IV disease. This study assessed the safety and effectiveness of salvage surgery following tyrosine kinase inhibitor (TKI) or immune checkpoint inhibitor (ICI) therapy in primary lung cancer.</p><p><strong>Methods: </strong>A retrospective chart review was conducted of 2050 primary lung cancer surgeries performed at our institution between 2012 and 2022. The study included patients who underwent salvage surgery for unresectable lesions that became resectable or localized residual lesions after treatment. We investigated patients' clinicopathological characteristics, therapeutic responses, and survival outcomes.</p><p><strong>Results: </strong>We identified eight cases of salvage surgery after TKI treatment and eight cases after ICI treatment. Five patients experienced early recurrence after surgery; however, the long-term outcome in the post-TKI group was favorable, with a median overall survival (OS) of 66 (range: 28-80) months. Postoperative recurrence was confined to local lymph node recurrence in one patient in the post-ICI group. Despite the relatively short observation period, the long-term prognosis remained promising, with a median OS of 18.7 (range: 9.7-55.8) months.</p><p><strong>Conclusions: </strong>Salvage surgery after TKI or ICI treatment can be safely performed, and the OS may be favorable.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140132630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a laparoscopic sigmoidectomy simulator: Sigmaster. 开发腹腔镜乙状结肠切除术模拟器:Sigmaster.
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-01 Epub Date: 2024-05-14 DOI: 10.1007/s00595-024-02855-5
Takahiro Shigaki, Hiro Hasegawa, Koichi Teramura, Nobuyoshi Takeshita, Koji Ikeda, Yuichiro Tsukada, Yuji Nishizawa, Takeshi Sasaki, Masaaki Ito
{"title":"Development of a laparoscopic sigmoidectomy simulator: Sigmaster.","authors":"Takahiro Shigaki, Hiro Hasegawa, Koichi Teramura, Nobuyoshi Takeshita, Koji Ikeda, Yuichiro Tsukada, Yuji Nishizawa, Takeshi Sasaki, Masaaki Ito","doi":"10.1007/s00595-024-02855-5","DOIUrl":"10.1007/s00595-024-02855-5","url":null,"abstract":"<p><p>The sigmoid colon simulator was designed to accurately reproduce the anatomical layer structure and the arrangement of characteristic organs in each layer, and to have conductivity so that energy devices can be used. Dry polyester fibers were used to reproduce the layered structures, which included characteristic blood vessels, nerve sheaths, and intestinal tracts. The adhesive strength of the layers was controlled to allow realistic peeling techniques. The features of the Sigmaster are illustrated through a comparison of simulated sigmoidectomy using Sigmaster and actual surgery. We developed a laparoscopic sigmoidectomy simulator called Sigmaster. Sigmaster is a training device that closely reproduces the membrane structures of the human body and allows surgeons to experience the entire laparoscopic sigmoidectomy process.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Right-sided versus left-sided colorectal cancer in elderly patients: a sub-analysis of a large multicenter case-control study in Japan. 老年患者的右侧与左侧结直肠癌:日本一项大型多中心病例对照研究的子分析。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-01 Epub Date: 2024-06-05 DOI: 10.1007/s00595-024-02827-9
Haruki Sada, Takao Hinoi, Hiroaki Niitsu, Hideki Ohdan, Seiichiro Yamamoto, Shungo Endo, Koya Hida, Yusuke Kinugasa, Toshiyuki Enomoto, Satoshi Maruyama, Fumio Konishi, Masahiko Watanabe
{"title":"Right-sided versus left-sided colorectal cancer in elderly patients: a sub-analysis of a large multicenter case-control study in Japan.","authors":"Haruki Sada, Takao Hinoi, Hiroaki Niitsu, Hideki Ohdan, Seiichiro Yamamoto, Shungo Endo, Koya Hida, Yusuke Kinugasa, Toshiyuki Enomoto, Satoshi Maruyama, Fumio Konishi, Masahiko Watanabe","doi":"10.1007/s00595-024-02827-9","DOIUrl":"10.1007/s00595-024-02827-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the impact of sidedness of colorectal cancer (CRC) in elderly patients on the prognosis.</p><p><strong>Methods: </strong>In a sub-analysis of a multicenter case-control study of CRC patients who underwent surgery at ≥ 80 years old conducted in Japan between 2003 and 2007, both short- and long-term outcomes were compared between right-sided colon cancers (RCCs) and left-sided colorectal cancers (LCCs). RCCs were defined as those located from the cecum to the transverse colon.</p><p><strong>Results: </strong>Among the 1680 patients who underwent curative surgery, 812 and 868 had RCCs and LCCs, respectively. RCCs were more frequent than LCCs in those who were female, had renal comorbidities, and had a history of abdominal surgery. Regarding tumor characteristics, RCCs were larger, invaded more deeply, and were diagnosed as either mucinous or signet ring-cell carcinoma more frequently than LCCs. Regarding the prognosis, patients with RCCs had a significantly longer cancer-specific survival (CS-S) and cancer-specific relapse-free survival (CS-RFS) than those with LCCs. Furthermore, sidedness was determined to be an independent prognostic factor for CS-S and CS-RFS.</p><p><strong>Conclusion: </strong>RCCs, which accounted for half of the cases in patients ≥ 80 years old, showed better long-term outcomes than LCCs.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simple pelvimetry predicts the pelvic manipulation time in robot-assisted low and ultra-low anterior resection for rectal cancer. 简单骨盆测量法预测机器人辅助低位和超低位直肠癌前切除术的骨盆操作时间。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-01 Epub Date: 2024-03-29 DOI: 10.1007/s00595-024-02820-2
Takaaki Fujimoto, Koji Tamura, Kinuko Nagayoshi, Yusuke Mizuuchi, Fumika Goto, Hironao Matsuda, Kohei Horioka, Koji Shindo, Kohei Nakata, Kenoki Ohuchida, Masafumi Nakamura
{"title":"Simple pelvimetry predicts the pelvic manipulation time in robot-assisted low and ultra-low anterior resection for rectal cancer.","authors":"Takaaki Fujimoto, Koji Tamura, Kinuko Nagayoshi, Yusuke Mizuuchi, Fumika Goto, Hironao Matsuda, Kohei Horioka, Koji Shindo, Kohei Nakata, Kenoki Ohuchida, Masafumi Nakamura","doi":"10.1007/s00595-024-02820-2","DOIUrl":"10.1007/s00595-024-02820-2","url":null,"abstract":"<p><strong>Purpose: </strong>This study explored the difficulty factors in robot-assisted low and ultra-low anterior resection, focusing on simple measurements of the pelvic anatomy.</p><p><strong>Methods: </strong>This was a retrospective analysis of the clinical data of 61 patients who underwent robot-assisted low and ultra-low anterior resection for rectal cancer between October 2018 and April 2023. The relationship between the operative time in the pelvic phase and clinicopathological data, especially pelvic anatomical parameters measured on X-ray and computed tomography (CT), was evaluated. The operative time in the pelvic phase was defined as the time between mobilization from the sacral promontory and rectal resection.</p><p><strong>Results: </strong>Robot-assisted low and ultra-low anterior resections were performed in 32 and 29 patients, respectively. The median operative time in the pelvic phase was 126 (range, 31-332) min. A multiple linear regression analysis showed that a short distance from the anal verge to the lower edge of the cancer, a narrow area comprising the iliopectineal line, short anteroposterior and transverse pelvic diameters, and a small angle of the pelvic mesorectum were associated with a prolonged operative time in the pelvic phase.</p><p><strong>Conclusion: </strong>Simple pelvic anatomical measurements using abdominal radiography and CT may predict the pelvic manipulation time in robot-assisted surgery for rectal cancer.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the comments on: The effect of low preoperative albumin on long-term mortality: a meta-regression. 对相关评论的回应:术前低白蛋白对长期死亡率的影响:元回归。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-10-01 Epub Date: 2024-05-18 DOI: 10.1007/s00595-024-02870-6
Ruoxin Xu, Wenxiong Zhang
{"title":"Response to the comments on: The effect of low preoperative albumin on long-term mortality: a meta-regression.","authors":"Ruoxin Xu, Wenxiong Zhang","doi":"10.1007/s00595-024-02870-6","DOIUrl":"10.1007/s00595-024-02870-6","url":null,"abstract":"","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative strength of ligature points achieved by various surgical knot-tying techniques: an observational study using Maxon™ monofilament sutures. 各种手术打结技术实现的韧带点强度比较:使用 Maxon™ 单丝缝合线进行的观察研究。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-09-28 DOI: 10.1007/s00595-024-02936-5
Shoichi Tsuzaka, Yuji Konishi, Kazuhiro Mino, Naotake Honma, Hideki Kawamura, Takuto Yoshida, Akinobu Taketomi
{"title":"Comparative strength of ligature points achieved by various surgical knot-tying techniques: an observational study using Maxon™ monofilament sutures.","authors":"Shoichi Tsuzaka, Yuji Konishi, Kazuhiro Mino, Naotake Honma, Hideki Kawamura, Takuto Yoshida, Akinobu Taketomi","doi":"10.1007/s00595-024-02936-5","DOIUrl":"https://doi.org/10.1007/s00595-024-02936-5","url":null,"abstract":"<p><strong>Purpose: </strong>Surgical knot-tying requires careful selection of the appropriate technique for optimal outcomes; however, evidence is lacking about the common ligation techniques combining square and slip knots (combination knots). This study investigates the strength of a combination knot, compared with other techniques.</p><p><strong>Methods: </strong>In this observational cohort study, we assessed the strengths of square, slip-granny, slip-reef, and combination knots using absorbable monofilament sutures, and compared them using ANOVA and a multilevel linear regression analysis. We also assessed the correlation between the number of throws and knot strength using Spearman's correlation analysis.</p><p><strong>Results: </strong>Among 80 ligatures, ANOVA indicated significant differences in knot strength among the techniques (p < 0.01). Multilevel linear regression showed that a combination knot was stronger than a slip knot (p < 0.01) and comparable to a square knot (p = 0.0721). Secondary analysis indicated that for combination knots, five throws could achieve sufficient knot strength.</p><p><strong>Conclusion: </strong>Combination knots are as strong as square knots and stronger than slip knots, and thus present a reasonable option for surgical ligation.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment selection pattern and prognostic factors in older patients with non-small cell lung cancer at recurrence: an observational study. 老年非小细胞肺癌复发患者的治疗选择模式和预后因素:一项观察性研究。
IF 1.7 4区 医学
Surgery Today Pub Date : 2024-09-27 DOI: 10.1007/s00595-024-02938-3
Dai Sonoda, Raito Maruyama, Yasuto Kondo, Masahito Naito, Masashi Mikubo, Kazu Shiomi, Yukitoshi Satoh
{"title":"Treatment selection pattern and prognostic factors in older patients with non-small cell lung cancer at recurrence: an observational study.","authors":"Dai Sonoda, Raito Maruyama, Yasuto Kondo, Masahito Naito, Masashi Mikubo, Kazu Shiomi, Yukitoshi Satoh","doi":"10.1007/s00595-024-02938-3","DOIUrl":"https://doi.org/10.1007/s00595-024-02938-3","url":null,"abstract":"<p><strong>Purpose: </strong>Society is aging, and the proportion of older patients with lung cancer is increasing. However, the treatment choices and prognoses for older patients with cancer recurrence remain unclear. We retrospectively investigated the treatment choices and prognoses of older patients with recurrence.</p><p><strong>Methods: </strong>We conducted a retrospective review of 1100 patients who underwent complete resection for non-small cell lung cancer at Kitasato University Hospital between 2004 and 2017. Patients of ≥75 years of age were defined as older patients, and the prognosis and prognostic factors of these patients upon recurrence were examined.</p><p><strong>Results: </strong>Among the 290 patients who developed recurrence, 106 experienced recurrence at an older age. The factors associated with survival after recurrence included sex, time to recurrence, number of recurrences, performance status at recurrence, and active treatment. As the age at recurrence increased, the proportion of patients who did not receive active treatment increased, as did the proportion for whom the reason was the patient's and family's preferences.</p><p><strong>Conclusions: </strong>A considerable number of older patients who experience recurrence do not wish to receive active treatment. However, the prognosis can be improved by aggressive treatment for recurrence.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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