Surgery Today最新文献_第10页

Early-onset hepatic veno-occlusive disease after liver transplantation: an institutional experience and analysis of a literature-based cohort. 肝移植后早发性肝静脉闭塞症：机构经验和文献队列分析。

IF 2.5 4区医学

Surgery Today Pub Date : 2024-07-01 Epub Date: 2023-12-06 DOI: 10.1007/s00595-023-02770-1

Yutaka Endo, Masahiro Shinoda, Junki Maehara, Taizo Hibi, Yasushi Hasegawa, Hideaki Obara, Minoru Kitago, Hidenori Ojima, Minoru Tanabe, Yuko Kitagawa

{"title":"Early-onset hepatic veno-occlusive disease after liver transplantation: an institutional experience and analysis of a literature-based cohort.","authors":"Yutaka Endo, Masahiro Shinoda, Junki Maehara, Taizo Hibi, Yasushi Hasegawa, Hideaki Obara, Minoru Kitago, Hidenori Ojima, Minoru Tanabe, Yuko Kitagawa","doi":"10.1007/s00595-023-02770-1","DOIUrl":"10.1007/s00595-023-02770-1","url":null,"abstract":"Purpose: Hepatic veno-occlusive disease (HVOD) after liver transplantation (LT) is almost always a fatal complication. We assessed the outcomes of HVOD in a single institute and analyzed a literature-based cohort.Methods: We reviewed the medical records of recipients of LT performed between 1995 and 2020 at our institute and the literature on HVOD after LT. We then analyzed the clinical features based on a \"pooled\" cohort of cases identified in our institute and reported in the literature.Results: HVOD was diagnosed in 3 of 331 LT recipients, all of whom died in hospital, on days 164, 12, and 13, respectively. Our comprehensive review of the literature, as well as our cases, identified eight cases of HVOD that developed within 14 days after LT (early-onset type). Early-onset HVOD had a significantly worse prognosis than HVOD that developed beyond 2 weeks after LT (non-early-onset type), which was identified in 22 cases (25.0% vs. 86.1% of the 3-month graft survival rate). The most common causes of early-onset and non-early-onset types were acute cellular rejection (50%) and drug-induced disease (50%), respectively.Conclusion: Early-onset HVOD developing within 14 days after LT has a poor prognosis.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mac-2 binding protein glycosylation isomer as a novel predictor of early recurrence after resection for hepatocellular carcinoma. Mac-2结合蛋白糖基化异构体是预测肝细胞癌切除术后早期复发的新指标。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-06-28 DOI: 10.1007/s00595-024-02885-z

Kyohei Yugawa, Takashi Maeda, Keiji Tsuji, Mototsugu Shimokawa, Akihiro Sakai, Shohei Yamaguchi, Kozo Konishi, Kenkichi Hashimoto

{"title":"Mac-2 binding protein glycosylation isomer as a novel predictor of early recurrence after resection for hepatocellular carcinoma.","authors":"Kyohei Yugawa, Takashi Maeda, Keiji Tsuji, Mototsugu Shimokawa, Akihiro Sakai, Shohei Yamaguchi, Kozo Konishi, Kenkichi Hashimoto","doi":"10.1007/s00595-024-02885-z","DOIUrl":"https://doi.org/10.1007/s00595-024-02885-z","url":null,"abstract":"Purpose: Hepatocellular carcinoma (HCC) frequently recurs after radical resection, resulting in a poor prognosis. This study assessed the prognostic value of Mac-2 binding protein glycosylation isomer (M2BPGi) for early recurrence (ER) in patients with HCC.Methods: Patients who underwent radical resection for HCC between 2015 and 2021. HCC recurrence within one year after curative resection was defined as ER.Results: The 150 patients were divided into two groups: non-ER (116, 77.3%) and ER (34, 22.7%). The ER group had a lower overall survival rate (p < 0.0001) and significantly higher levels of M2BPGi (1.06 vs. 2.74 COI, p < 0.0001) than the non-ER group. High M2BPGi levels (odds ratio [OR] 1.78, 95% confidence interval [CI] 1.31-2.41, p < 0.0001) and a large tumor size (OR 1.31, 95% CI, 1.05-1.63; p = 0.0184) were identified as independent predictors of ER. M2BPGi was the best predictor of ER according to a receiver operating characteristic (ROC) analysis (area under the ROC curve 0.82, p < 0.0001).Conclusions: M2BPGi can predict ER after surgery and is useful for risk stratification in patients with HCC.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distal gastrectomy and Roux-en-Y reconstruction for refractory reflux esophagitis after proximal gastrectomy and esophagogastric anastomosis reconstruction. 远端胃切除术和 Roux-en-Y 重建术治疗近端胃切除术和食管胃吻合术重建后的难治性反流性食管炎。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-06-28 DOI: 10.1007/s00595-024-02889-9

Masaaki Yamamoto, Atsushi Takeno, Takuya Hamakawa, Shinji Tokuyama, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Kunihito Gotoh, Takeshi Kato, Motohiro Hirao

引用次数: 0

Usefulness of laparoscopic surgery for colorectal perforation: a single-center retrospective cohort study. 腹腔镜手术治疗结直肠穿孔的实用性：一项单中心回顾性队列研究。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-06-26 DOI: 10.1007/s00595-024-02886-y

Nobuhisa Tanioka, Michio Kuwahara, Hiromichi Maeda, Naoki Edo, Yuzuko Nokubo, Shigeto Shimizu, Toyokazu Akimori, Satoru Seo

{"title":"Usefulness of laparoscopic surgery for colorectal perforation: a single-center retrospective cohort study.","authors":"Nobuhisa Tanioka, Michio Kuwahara, Hiromichi Maeda, Naoki Edo, Yuzuko Nokubo, Shigeto Shimizu, Toyokazu Akimori, Satoru Seo","doi":"10.1007/s00595-024-02886-y","DOIUrl":"https://doi.org/10.1007/s00595-024-02886-y","url":null,"abstract":"Purpose: This study aimed to determine the safety and efficacy of laparoscopic surgery in patients with colorectal perforation owing to a significant lack of evidence in this field.Methods: This retrospective cohort study analyzed the data of 70 patients who underwent emergency surgery for colorectal perforations between January 2017 and December 2023. The surgical outcomes of the patients who underwent open and laparoscopic surgeries were statistically compared. The primary endpoints were postoperative mortality and complications. The secondary endpoints included blood loss, surgical time, length of hospital stay, and 1-year overall survival.Results: Overall, 28 patients underwent open surgery and 42 underwent laparoscopic surgery. No significant difference was noted in the postoperative mortality or overall rate of severe complications between the two groups. The incidence of superficial and deep incisional surgical site infection was lower in the laparoscopic surgery group (35.7% vs. 0.0%, p < 0.001), while the surgical time was significantly longer in the laparoscopic group (175.6 ± 92.2 min vs. 290.0 ± 102.3 min, p < 0.001). No significant differences were found in blood loss, length of hospital stay, or 1-year overall survival.Conclusions: Laparoscopic surgery for colorectal perforation markedly reduced superficial and deep incisional surgical site infection, with no substantial difference in mortality or severe complications.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current status of the surgical training system in Japan: results of a nationwide questionnaire survey of graduating surgical trainees. 日本外科培训制度的现状：对即将毕业的外科学员进行的全国性问卷调查结果。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-06-26 DOI: 10.1007/s00595-024-02884-0

Yoshiyuki Kiyasu, Saseem Poudel, Daisuke Koike, Jun Watanabe, Ryosuke Kowatari, Masayuki Fukumoto, Yoshiko Yamaoka-Fujikawa, Yuta Kikuchi, Keisuke Arai, Eisuke Booka, Sonoko Ishida, Shinichiro Yokoyama, Mitsue Saito

{"title":"Current status of the surgical training system in Japan: results of a nationwide questionnaire survey of graduating surgical trainees.","authors":"Yoshiyuki Kiyasu, Saseem Poudel, Daisuke Koike, Jun Watanabe, Ryosuke Kowatari, Masayuki Fukumoto, Yoshiko Yamaoka-Fujikawa, Yuta Kikuchi, Keisuke Arai, Eisuke Booka, Sonoko Ishida, Shinichiro Yokoyama, Mitsue Saito","doi":"10.1007/s00595-024-02884-0","DOIUrl":"https://doi.org/10.1007/s00595-024-02884-0","url":null,"abstract":"Purpose: To identify the problems trainees face during surgical training in Japan.Methods: A nationwide online questionnaire survey was conducted targeting newly certified surgical trainees.Results: The response rate was 53.8% (758/1410). Among those respondents, 25.6% were women, 71.4% were either married or had a partner, 41.3% had children, 72.7% had performed over 200 surgeries under general anesthesia, and 54.1% had chosen, before graduating from medical school, to become a surgeon. While 88.8% were interested in learning surgical techniques, 63.8% were hesitant to become a surgeon for fear of a compromised quality of private life (QOL). Conversely, only 1.4% chose their surgical training programs based on QOL. Overall, 84.6% of the trainees were satisfied with their training and this correlated with the number of surgeries performed. Only 29.9% received non-technical skill training. The average number of night shifts per month was 5.6, and 10.6% worked over 80 h per week. Harassment was reported by 41.5% of the respondents. Moreover, 33.0% had considered dropping out at some time, primarily because of their QOL (51.1%) or the harassment they had encountered (50.4%).Conclusion: This survey revealed that while trainees were satisfied with the overall training system, issues such as long working hours and harassment are prevalent. Working to improve these issues could make surgery more attractive for young trainees.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term outcomes of robotic subxiphoid-optical thymectomy. 机器人剑突下-光学胸腺切除术的短期疗效。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-06-24 DOI: 10.1007/s00595-024-02887-x

Masanori Shimomura, Satoru Okada, Tatsuo Furuya, Rina Oya, Yuka Hirakawa, Fumimasa Amaya, Masayoshi Inoue

{"title":"Short-term outcomes of robotic subxiphoid-optical thymectomy.","authors":"Masanori Shimomura, Satoru Okada, Tatsuo Furuya, Rina Oya, Yuka Hirakawa, Fumimasa Amaya, Masayoshi Inoue","doi":"10.1007/s00595-024-02887-x","DOIUrl":"https://doi.org/10.1007/s00595-024-02887-x","url":null,"abstract":"Purpose: To evaluate the usefulness of robotic subxiphoid-optical thymectomy (RST).Methods: Thirty-seven procedures (thymoma, n = 19; thymic carcinoma, n = 1; myasthenia gravis, n = 3; and others, n = 14) performed between October 2020 and December 2023 were included. The right and left 6th intercostal midclavicular lines and subxiphoid, with an assistant port placed in the right third intercostal anterior axillary line, were adapted. Postoperative pain was assessed using a numerical rating scale (NRS).Results: A good view of the surgical field is obtained. The median console time was 113 min and the time to roll-in was 30 min. The body mass index (BMI) was 21.6. One patient with thymic carcinoma required combined resection of the left phrenic nerve and left brachiocephalic vein without conversion to thoracotomy, and 1 patient had post-pericardiotomy syndrome with bilateral pleural effusion. There was a correlation between the prolonged time to roll-in and BMI (ρ = 0.439; p = 0.007). Pain was controlled with oral medication on postoperative day 1 and significantly decreased at discharge and at the first outpatient visit without epidural anesthesia (median NRS scores: 4, 1, and 1, respectively).Conclusion: RST is a safe procedure that provides surgeons with a sufficient view of the anterior mediastinum and causes minimal postoperative pain.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The long-term quality of life after distal and pylorus-preserving gastrectomy for stage I gastric cancer: A prospective multi-institutional study (CCOG1601). I 期胃癌远端和幽门保留胃切除术后的长期生活质量：一项前瞻性多机构研究（CCOG1601）。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-06-21 DOI: 10.1007/s00595-024-02881-3

Chie Tanaka, Mitsuro Kanda, Kazunari Misawa, Yoshinari Mochizuki, Takuya Watanabe, Masashi Hattori, Kiyoshi Ishigure, Satoshi Sueoka, Hitoshi Teramoto, Akiharu Ishiyama, Ikue Nonogaki, Hidenobu Matsushita, Kenta Murotani, Yasuhiro Kodera

{"title":"The long-term quality of life after distal and pylorus-preserving gastrectomy for stage I gastric cancer: A prospective multi-institutional study (CCOG1601).","authors":"Chie Tanaka, Mitsuro Kanda, Kazunari Misawa, Yoshinari Mochizuki, Takuya Watanabe, Masashi Hattori, Kiyoshi Ishigure, Satoshi Sueoka, Hitoshi Teramoto, Akiharu Ishiyama, Ikue Nonogaki, Hidenobu Matsushita, Kenta Murotani, Yasuhiro Kodera","doi":"10.1007/s00595-024-02881-3","DOIUrl":"https://doi.org/10.1007/s00595-024-02881-3","url":null,"abstract":"Purpose: While regarded as function-preserving gastrectomy, few prospective longitudinal clinical trials have addressed the postoperative quality of life (QOL) after pylorus-preserving gastrectomy (PPG). We prospectively compared chronological changes in postoperative body weight and the QOL between PPG and distal gastrectomy (DG) for pathological Stage I gastric cancer (GC).Methods: We conducted a multi-institutional prospective study (CCOG1601) to evaluate patients who underwent DG and PPG. The QOL was examined using the European Organization for Research and Treatment of Cancer Quality of life questionnaire-C30 (EORTC QLQ-C30) and the Post-Gastrectomy Syndrome Assessment Scale-37 (PGSAS-37). A total of 295 patients were enrolled from 15 institutions, and propensity score matching was performed to adjust for the essential variables for comparison analyses.Results: After propensity score matching, 25 pairs of patients were identified. In the first postoperative month, DG achieved a superior nausea and vomiting score (EORTC QLQ-C30) and meal-related distress, indigestion, and dumping scores (PGSAS-37). No significant differences were noted between DG and PPG in the long-term QOL. Postoperative body weight loss was similar in both groups.Conclusions: This prospective observational study failed to demonstrate the superiority of PPG over DG in terms of postoperative body weight changes and the QOL.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a machine learning-based risk model for postoperative complications of lung cancer surgery. 开发基于机器学习的肺癌术后并发症风险模型。

IF 2.5 4区医学

Surgery Today Pub Date : 2024-06-19 DOI: 10.1007/s00595-024-02878-y

Yuka Kadomatsu, Ryo Emoto, Yoko Kubo, Keita Nakanishi, Harushi Ueno, Taketo Kato, Shota Nakamura, Tetsuya Mizuno, Shigeyuki Matsui, Toyofumi Fengshi Chen-Yoshikawa

{"title":"Development of a machine learning-based risk model for postoperative complications of lung cancer surgery.","authors":"Yuka Kadomatsu, Ryo Emoto, Yoko Kubo, Keita Nakanishi, Harushi Ueno, Taketo Kato, Shota Nakamura, Tetsuya Mizuno, Shigeyuki Matsui, Toyofumi Fengshi Chen-Yoshikawa","doi":"10.1007/s00595-024-02878-y","DOIUrl":"https://doi.org/10.1007/s00595-024-02878-y","url":null,"abstract":"Purpose: To develop a comorbidity risk score specifically for lung resection surgeries.Methods: We reviewed the medical records of patients who underwent lung resections for lung cancer, and developed a risk model using data from 2014 to 2017 (training dataset), validated using data from 2018 to 2019 (validation dataset). Forty variables were analyzed, including 35 factors related to the patient's overall condition and five factors related to surgical techniques and tumor-related factors. The risk model for postoperative complications was developed using an elastic net regularized generalized linear model. The performance of the risk model was evaluated using receiver operating characteristic curves and compared with the Charlson Comorbidity Index (CCI).Results: The rate of postoperative complications was 34.7% in the training dataset and 21.9% in the validation dataset. The final model consisted of 20 variables, including age, surgical-related factors, respiratory function tests, and comorbidities, such as chronic obstructive pulmonary disease, a history of ischemic heart disease, and 12 blood test results. The area under the curve (AUC) for the developed risk model was 0.734, whereas the AUC for the CCI was 0.521 in the validation dataset.Conclusions: The new machine learning model could predict postoperative complications with acceptable accuracy.Clinical registration number: 2020-0375.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteosarcopenia: the coexistence of sarcopenia and osteopenia is predictive of prognosis and postoperative complications after curative resection for colorectal cancer. 骨质疏松症：肌肉疏松症和骨质疏松症并存可预测结肠直肠癌根治性切除术后的预后和术后并发症。

IF 2.5 4区医学

Surgery Today Pub Date : 2024-06-16 DOI: 10.1007/s00595-024-02883-1

Takaaki Fujimoto, Koji Tamura, Kinuko Nagayoshi, Yusuke Mizuuchi, Yoshio Oh, Tsukasa Nara, Hiroshi Matsumoto, Kohei Horioka, Koji Shindo, Kohei Nakata, Kenoki Ohuchida, Masafumi Nakamura

{"title":"Osteosarcopenia: the coexistence of sarcopenia and osteopenia is predictive of prognosis and postoperative complications after curative resection for colorectal cancer.","authors":"Takaaki Fujimoto, Koji Tamura, Kinuko Nagayoshi, Yusuke Mizuuchi, Yoshio Oh, Tsukasa Nara, Hiroshi Matsumoto, Kohei Horioka, Koji Shindo, Kohei Nakata, Kenoki Ohuchida, Masafumi Nakamura","doi":"10.1007/s00595-024-02883-1","DOIUrl":"https://doi.org/10.1007/s00595-024-02883-1","url":null,"abstract":"Purpose: To establish if osteosarcopenia is related to postoperative complications, prognosis, and recurrence of colorectal cancer (CRC) after curative surgery.Methods: The clinical data of 594 patients who underwent curative resection for CRC between January, 2013 and December, 2018 were analyzed retrospectively to examine the relationship between clinicopathological data and osteosarcopenia. The following definitions were used: sarcopenia, low skeletal muscle mass index; osteopenia, low bone mineral density on computed tomography at the level of the 11th thoracic vertebra; and osteosarcopenia, sarcopenia with osteopenia.Results: Osteosarcopenia was identified in 98 patients (16.5%) and found to be a significant risk factor for postoperative complications (odds ratio 2.53; p = 0.011). The 5-year overall survival (OS) and recurrence-free survival (RFS) rates of the patients with osteosarcopenia were significantly lower than those of the patients without osteosarcopenia (OS: 72.5% and 93.9%, respectively, p < 0.0001; RFS: 70.8% and 92.4%, respectively, p < 0.0001). Multivariate analysis identified osteosarcopenia as an independent prognostic factor associated with OS (hazard ratio 3.31; p < 0.0001) and RFS (hazard ratio 3.67; p < 0.0001).Conclusion: Osteosarcopenia may serve as a predictor of postoperative complications and prognosis after curative surgery for CRC.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abdominal aortic calcification volume as a preoperative prognostic predictor for pancreatic cancer. 作为胰腺癌术前预后预测指标的腹主动脉钙化体积。

IF 2.5 4区医学

Surgery Today Pub Date : 2024-06-16 DOI: 10.1007/s00595-024-02882-2

Yuta Yamada, Kenei Furukawa, Koichiro Haruki, Norimitsu Okui, Yoshihiro Shirai, Masashi Tsunematsu, Mitsuru Yanagaki, Jungo Yasuda, Shinji Onda, Toru Ikegami

{"title":"Abdominal aortic calcification volume as a preoperative prognostic predictor for pancreatic cancer.","authors":"Yuta Yamada, Kenei Furukawa, Koichiro Haruki, Norimitsu Okui, Yoshihiro Shirai, Masashi Tsunematsu, Mitsuru Yanagaki, Jungo Yasuda, Shinji Onda, Toru Ikegami","doi":"10.1007/s00595-024-02882-2","DOIUrl":"https://doi.org/10.1007/s00595-024-02882-2","url":null,"abstract":"Purpose: Atherosclerosis and cancer may progress through common pathological factors. This study was performed to investigate the association between the abdominal aortic calcification (AAC) volume and outcomes following surgical treatment for pancreatic cancer.Methods: The subjects of this retrospective study were 194 patients who underwent pancreatic cancer surgery between 2007 and 2020. The AAC volume was assessed through routine preoperative computed tomography. Univariate and multivariate analyses were performed to evaluate the impact of the AAC volume on oncological outcomes.Results: A higher AAC volume (≥ 312 mm3) was identified in 66 (34%) patients, who were significantly older and had a higher prevalence of diabetes and sarcopenia. Univariate analysis revealed several risk factors for overall survival (OS), including male sex, an AAC volume ≥ 312 mm3, elevated carbohydrate antigen 19-9, prolonged operation time, increased intraoperative bleeding, lymph node metastasis, poor differentiation, and absence of adjuvant chemotherapy. Multivariate analysis identified an AAC volume ≥ 312 mm3, prolonged operation time, lymph node metastasis, poor differentiation, and absence of adjuvant chemotherapy as independent OS risk factors. The OS rate was significantly lower in the high AAC group than in the low AAC group.Conclusion: The AAC volume may serve as a preoperative prognostic indicator for patients with pancreatic cancer.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0