Surgery Today最新文献_第2页

Laparoscopic vs. open surgery for rectal cancer in patients with obesity: short-term outcomes and relapse-free survival across age groups. 肥胖症患者直肠癌腹腔镜手术与开腹手术：不同年龄组的短期疗效和无复发生存率。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-08-05 DOI: 10.1007/s00595-024-02901-2

Yusuke Fujita, Koya Hida, Nobuaki Hoshino, Tomonori Akagi, Kentaro Nakajima, Masafumi Inomata, Seiichiro Yamamoto, Yoshiharu Sakai, Takeshi Naitoh, Kazutaka Obama

{"title":"Laparoscopic vs. open surgery for rectal cancer in patients with obesity: short-term outcomes and relapse-free survival across age groups.","authors":"Yusuke Fujita, Koya Hida, Nobuaki Hoshino, Tomonori Akagi, Kentaro Nakajima, Masafumi Inomata, Seiichiro Yamamoto, Yoshiharu Sakai, Takeshi Naitoh, Kazutaka Obama","doi":"10.1007/s00595-024-02901-2","DOIUrl":"10.1007/s00595-024-02901-2","url":null,"abstract":"Purpose: To investigate the efficacy of laparoscopic surgery for rectal cancer in obese and older patients, who are often characterized by a higher prevalence of comorbidities and physical decline.Methods: This large-scale multicenter retrospective cohort study included 524 patients with a body mass index of 25 or higher who underwent either open or laparoscopic surgery for stage II or III rectal cancer between 2009 and 2013. We assessed the short-term outcomes and relapse-free survival by comparing these surgical modalities. The patients were stratified into 404 non-elderly (< 70 years) and 120 elderly (≥ 70 years) patients.Results: In both patient groups, laparoscopic surgery was associated with a significantly reduced blood loss (non-elderly: 41 vs. 545 ml; elderly: 50 vs. 445 ml) and shorter hospital stays (non-elderly: 10 vs. 19 days; elderly: 15 vs. 20 days) than open surgery. The overall complications and relapse-free survival showed no significant differences between the two surgical techniques in either age group. Additionally, the impact of the laparoscopic procedure on the relapse-free survival remained consistent between the age groups.Conclusion: Laparoscopic surgery offers short-term benefits for patients with obesity and rectal cancer compared to open surgery, regardless of age, without influencing the long-term prognosis.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"10-17"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Authors' response to Letter to the Editor. 作者对致函编辑的回复。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-08-06 DOI: 10.1007/s00595-024-02916-9

Yoko Azuma, Akira Iyoda

引用次数: 0

True predictor of postoperative acute exacerbation of idiopathic interstitial pneumonia in lung cancer patients. 肺癌患者术后特发性间质性肺炎急性加重的真正预测因素。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-06-12 DOI: 10.1007/s00595-024-02873-3

Yongliang Wang, Zheng Bao

引用次数: 0

Surgical interpretation of the WHO subclassification of intrahepatic cholangiocarcinoma: a narrative review. 世界卫生组织肝内胆管癌亚分类的外科解释：叙述性综述。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-04-02 DOI: 10.1007/s00595-024-02825-x

Masayuki Akita, Hiroaki Yanagimoto, Daisuke Tsugawa, Yoh Zen, Takumi Fukumoto

{"title":"Surgical interpretation of the WHO subclassification of intrahepatic cholangiocarcinoma: a narrative review.","authors":"Masayuki Akita, Hiroaki Yanagimoto, Daisuke Tsugawa, Yoh Zen, Takumi Fukumoto","doi":"10.1007/s00595-024-02825-x","DOIUrl":"10.1007/s00595-024-02825-x","url":null,"abstract":"Intrahepatic cholangiocarcinoma (iCCA) has been subclassified by its gross morphology into the mass-forming (MF), periductal-infiltrating (PI), and intraductal growth (IG) types and their combinations. This classification correlates well with clinical features; for example, MF-iCCA has less lymph-node metastasis and a better prognosis than PI-iCCA. According to the recently accumulated evidence from histological investigations, the WHO classification endorsed a subclassification scheme in which iCCA cases are classified into small- and large-duct types. Small-duct iCCA is considered to originate from septal or smaller bile ducts and is characterized by less frequent lymph-node metastasis, a favorable prognosis, and an MF appearance. Large-duct iCCA arises around the second branch of the biliary tree and has more aggressive biology and distinct genetic abnormalities. According to the practice guidelines for iCCA from the Liver Cancer Study Group of Japan and the National Comprehensive Cancer Network, upfront surgery is recommended for iCCA without distant metastasis regardless of the morphological subtype, based on clinical experience. In consideration of the biological heterogeneity of iCCA, the treatment strategy for iCCA needs to be reconsidered based on the WHO subtypes.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140336865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the lymphocyte-to-monocyte ratio on the prognosis of patients with obstructive colorectal cancer with a colonic stent: a retrospective multicenter study in Japan. 淋巴细胞与单核细胞比率对使用结肠支架的阻塞性结直肠癌患者预后的影响：日本一项回顾性多中心研究。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-06-10 DOI: 10.1007/s00595-024-02875-1

Toshio Shiraishi, Tetsuro Tominaga, Takashi Nonaka, Yuma Takamura, Kaido Oishi, Shintaro Hashimoto, Keisuke Noda, Rika Ono, Makoto Hisanaga, Hiroaki Takeshita, Mitsutoshi Ishii, Syosaburo Oyama, Kazuhide Ishimaru, Masaki Kunizaki, Terumitsu Sawai, Keitaro Matsumoto

{"title":"Effect of the lymphocyte-to-monocyte ratio on the prognosis of patients with obstructive colorectal cancer with a colonic stent: a retrospective multicenter study in Japan.","authors":"Toshio Shiraishi, Tetsuro Tominaga, Takashi Nonaka, Yuma Takamura, Kaido Oishi, Shintaro Hashimoto, Keisuke Noda, Rika Ono, Makoto Hisanaga, Hiroaki Takeshita, Mitsutoshi Ishii, Syosaburo Oyama, Kazuhide Ishimaru, Masaki Kunizaki, Terumitsu Sawai, Keitaro Matsumoto","doi":"10.1007/s00595-024-02875-1","DOIUrl":"10.1007/s00595-024-02875-1","url":null,"abstract":"Purpose: The prognostic value of the lymphocyte-to-monocyte (LMR) ratio has been reported for various cancers, including colorectal cancer (CRC). The insertion of colonic stents is considered effective for patients with surgically indicated obstructive CRC, but their LMR can vary depending on factors such as inflammation associated with stent dilation and improvement of obstructive colitis. However, the usefulness of the LMR in patients with obstructive CRC and colonic stents and the optimal timing for its measurement remain unclear. We conducted this study to investigate the relationship between the pre-stent LMR and the mid-term prognosis of patients with obstructive CRC and stents as a bridge to surgery (BTS).Methods: The subjects of this retrospective multicenter study were 175 patients with pathological stage 2 or 3 CRC. Patients were divided into a low pre-stent LMR group (n = 87) and a high pre-stent LMR group (n = 83).Results: Only 3-year relapse-free survival differed significantly between the low and high pre-stent LMR groups (39.9% vs. 63.6%, respectively; p = 0.015). The pre-stent LMR represented a prognostic factor for relapse-free survival in multivariate analyses (hazard ratio 2.052, 95% confidence interval 1.242-3.389; p = 0.005), but not for overall survival.Conclusions: A low pre-stent LMR is a prognostic factor for postoperative recurrence in patients with obstructive CRC and a colonic stent as a BTS.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"36-51"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abdominal aortic calcification volume as a preoperative prognostic predictor for pancreatic cancer. 作为胰腺癌术前预后预测指标的腹主动脉钙化体积。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-06-16 DOI: 10.1007/s00595-024-02882-2

Yuta Yamada, Kenei Furukawa, Koichiro Haruki, Norimitsu Okui, Yoshihiro Shirai, Masashi Tsunematsu, Mitsuru Yanagaki, Jungo Yasuda, Shinji Onda, Toru Ikegami

{"title":"Abdominal aortic calcification volume as a preoperative prognostic predictor for pancreatic cancer.","authors":"Yuta Yamada, Kenei Furukawa, Koichiro Haruki, Norimitsu Okui, Yoshihiro Shirai, Masashi Tsunematsu, Mitsuru Yanagaki, Jungo Yasuda, Shinji Onda, Toru Ikegami","doi":"10.1007/s00595-024-02882-2","DOIUrl":"10.1007/s00595-024-02882-2","url":null,"abstract":"Purpose: Atherosclerosis and cancer may progress through common pathological factors. This study was performed to investigate the association between the abdominal aortic calcification (AAC) volume and outcomes following surgical treatment for pancreatic cancer.Methods: The subjects of this retrospective study were 194 patients who underwent pancreatic cancer surgery between 2007 and 2020. The AAC volume was assessed through routine preoperative computed tomography. Univariate and multivariate analyses were performed to evaluate the impact of the AAC volume on oncological outcomes.Results: A higher AAC volume (≥ 312 mm3) was identified in 66 (34%) patients, who were significantly older and had a higher prevalence of diabetes and sarcopenia. Univariate analysis revealed several risk factors for overall survival (OS), including male sex, an AAC volume ≥ 312 mm3, elevated carbohydrate antigen 19-9, prolonged operation time, increased intraoperative bleeding, lymph node metastasis, poor differentiation, and absence of adjuvant chemotherapy. Multivariate analysis identified an AAC volume ≥ 312 mm3, prolonged operation time, lymph node metastasis, poor differentiation, and absence of adjuvant chemotherapy as independent OS risk factors. The OS rate was significantly lower in the high AAC group than in the low AAC group.Conclusion: The AAC volume may serve as a preoperative prognostic indicator for patients with pancreatic cancer.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"70-77"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative evaluation of visceral pleural invasion in peripheral lung cancer utilizing deep learning technology. 利用深度学习技术对周围型肺癌的内脏胸膜侵犯进行术前评估。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-05-23 DOI: 10.1007/s00595-024-02869-z

Yujin Kudo, Akira Saito, Tomoaki Horiuchi, Kotaro Murakami, Masaharu Kobayashi, Jun Matsubayashi, Toshitaka Nagao, Tatsuo Ohira, Masahiko Kuroda, Norihiko Ikeda

{"title":"Preoperative evaluation of visceral pleural invasion in peripheral lung cancer utilizing deep learning technology.","authors":"Yujin Kudo, Akira Saito, Tomoaki Horiuchi, Kotaro Murakami, Masaharu Kobayashi, Jun Matsubayashi, Toshitaka Nagao, Tatsuo Ohira, Masahiko Kuroda, Norihiko Ikeda","doi":"10.1007/s00595-024-02869-z","DOIUrl":"10.1007/s00595-024-02869-z","url":null,"abstract":"Purpose: This study aimed to assess the efficiency of artificial intelligence (AI) in the detection of visceral pleural invasion (VPI) of lung cancer using high-resolution computed tomography (HRCT) images, which is challenging for experts because of its significance in T-classification and lymph node metastasis prediction.Methods: This retrospective analysis was conducted on preoperative HRCT images of 472 patients with stage I non-small cell lung cancer (NSCLC), focusing on lesions adjacent to the pleura to predict VPI. YOLOv4.0 was utilized for tumor localization, and EfficientNetv2 was applied for VPI prediction with HRCT images meticulously annotated for AI model training and validation.Results: Of the 472 lung cancer cases (500 CT images) studied, the AI algorithm successfully identified tumors, with YOLOv4.0 accurately localizing tumors in 98% of the test images. In the EfficientNet v2-M analysis, the receiver operating characteristic curve exhibited an area under the curve of 0.78. It demonstrated powerful diagnostic performance with a sensitivity, specificity, and precision of 76.4% in VPI prediction.Conclusion: AI is a promising tool for improving the diagnostic accuracy of VPI for NSCLC. Furthermore, incorporating AI into the diagnostic workflow is advocated because of its potential to improve the accuracy of preoperative diagnosis and patient outcomes in NSCLC.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"18-28"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141088945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical outcomes of video-assisted neck surgery for papillary thyroid carcinoma. 视频辅助颈部手术治疗甲状腺乳头状癌的手术效果。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-06-06 DOI: 10.1007/s00595-024-02876-0

Mariko Misaki, Seiya Inoue, Naoya Kawakita, Taihei Takeuchi, Naoki Miyamoto, Shinichi Sakamoto, Satoshi Fujiwara, Masakazu Goto, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa

{"title":"Surgical outcomes of video-assisted neck surgery for papillary thyroid carcinoma.","authors":"Mariko Misaki, Seiya Inoue, Naoya Kawakita, Taihei Takeuchi, Naoki Miyamoto, Shinichi Sakamoto, Satoshi Fujiwara, Masakazu Goto, Mitsuhiro Tsuboi, Hiroaki Toba, Hiromitsu Takizawa","doi":"10.1007/s00595-024-02876-0","DOIUrl":"10.1007/s00595-024-02876-0","url":null,"abstract":"Purpose: New approaches to endoscopic thyroid surgery have been developed to improve cosmetic results, one of which is video-assisted neck surgery (VANS). The present study investigates the safety and effectiveness of thyroidectomy by VANS as oncologic surgery for papillary thyroid carcinoma (PTC).Methods: The subjects of this retrospective study were 121 patients with PTC, who underwent hemi-thyroid lobectomy and central lymph node dissection via open surgery (n = 102) or VANS (n = 19) at Tokushima University Hospital between 2011 and 2023. We performed 1:1 propensity score matching and then compared the surgical outcomes between the two matched groups.Results: Propensity score matching generated 18 distinct examination pairs. The VANS group had significantly less blood loss (P = 0.003), but a longer operative time (P < 0.001) than the open thyroidectomy group. There were two cases of transient recurrent laryngeal nerve paralysis and one case of recurrence in the lateral regional lymph nodes in the VANS group. However, no significant differences were observed in the incidence of complications (P = 0.243) or recurrence (P = 0.500) between the two groups.Conclusion: VANS is a safe and effective surgical procedure for PTC, but longer follow-up is needed to assess tumor recurrence.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"29-35"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current status of the surgical training system in Japan: results of a nationwide questionnaire survey of graduating surgical trainees. 日本外科培训制度的现状：对即将毕业的外科学员进行的全国性问卷调查结果。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-06-26 DOI: 10.1007/s00595-024-02884-0

Yoshiyuki Kiyasu, Saseem Poudel, Daisuke Koike, Jun Watanabe, Ryosuke Kowatari, Masayuki Fukumoto, Yoshiko Yamaoka-Fujikawa, Yuta Kikuchi, Keisuke Arai, Eisuke Booka, Sonoko Ishida, Shinichiro Yokoyama, Mitsue Saito

{"title":"Current status of the surgical training system in Japan: results of a nationwide questionnaire survey of graduating surgical trainees.","authors":"Yoshiyuki Kiyasu, Saseem Poudel, Daisuke Koike, Jun Watanabe, Ryosuke Kowatari, Masayuki Fukumoto, Yoshiko Yamaoka-Fujikawa, Yuta Kikuchi, Keisuke Arai, Eisuke Booka, Sonoko Ishida, Shinichiro Yokoyama, Mitsue Saito","doi":"10.1007/s00595-024-02884-0","DOIUrl":"10.1007/s00595-024-02884-0","url":null,"abstract":"Purpose: To identify the problems trainees face during surgical training in Japan.Methods: A nationwide online questionnaire survey was conducted targeting newly certified surgical trainees.Results: The response rate was 53.8% (758/1410). Among those respondents, 25.6% were women, 71.4% were either married or had a partner, 41.3% had children, 72.7% had performed over 200 surgeries under general anesthesia, and 54.1% had chosen, before graduating from medical school, to become a surgeon. While 88.8% were interested in learning surgical techniques, 63.8% were hesitant to become a surgeon for fear of a compromised quality of private life (QOL). Conversely, only 1.4% chose their surgical training programs based on QOL. Overall, 84.6% of the trainees were satisfied with their training and this correlated with the number of surgeries performed. Only 29.9% received non-technical skill training. The average number of night shifts per month was 5.6, and 10.6% worked over 80 h per week. Harassment was reported by 41.5% of the respondents. Moreover, 33.0% had considered dropping out at some time, primarily because of their QOL (51.1%) or the harassment they had encountered (50.4%).Conclusion: This survey revealed that while trainees were satisfied with the overall training system, issues such as long working hours and harassment are prevalent. Working to improve these issues could make surgery more attractive for young trainees.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"90-98"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is the use of direct oral anticoagulants after non-cardiac thoracic surgery safe for patients? 非心脏胸外科手术后使用直接口服抗凝剂对患者安全吗？

IF 1.7 4区医学

Surgery Today Pub Date : 2025-01-01 Epub Date: 2024-10-10 DOI: 10.1007/s00595-024-02942-7

Mari Ohkuma, Mariko Fukui, Aritoshi Hattori, Takeshi Matsunaga, Hisashi Tomita, Kazuya Takamochi, Kenji Suzuki

{"title":"Is the use of direct oral anticoagulants after non-cardiac thoracic surgery safe for patients?","authors":"Mari Ohkuma, Mariko Fukui, Aritoshi Hattori, Takeshi Matsunaga, Hisashi Tomita, Kazuya Takamochi, Kenji Suzuki","doi":"10.1007/s00595-024-02942-7","DOIUrl":"10.1007/s00595-024-02942-7","url":null,"abstract":"Purpose: The outcomes of direct oral anticoagulant use after noncardiac thoracic surgery have not been elucidated. We compared the safety and efficacy of the postoperative use of direct oral anticoagulants versus warfarin.Methods: This retrospective cohort study included patients taking anticoagulants after noncardiac thoracic surgery between 2008 and 2021. Patients were divided into 2 groups based on drug type: Group D (direct oral anticoagulants) and Group W (warfarin). The occurrence of bleeding and thromboembolic events was also assessed.Results: Anticoagulants were administered to 434 postoperative patients. One (0.4%) of the 247 patients in Group D and 3 (1.6%) of the 187 patients in Group W experienced thromboembolic events. Four patients (1.6%) in Group D and 4 (2.1%) patients in Group W experienced bleeding events. All bleeding events in Group D occurred within 1 week of oral administration, whereas only 1 case of bleeding occurred after resumption in Group W.Conclusions: The outcomes of patients treated with direct oral anticoagulants did not differ from those of patients treated with warfarin. However, major bleeding can occur after the postoperative resumption of direct oral anticoagulant use. Attention should be paid to resuming oral anticoagulants within a few days of non-cardiac thoracic surgery.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"116-122"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0