{"title":"Status of perioperative venous thromboembolism (VTE) prophylaxis in gastrointestinal surgery based on national clinical database (NCD) data in Japan.","authors":"Taishi Hata, Hiroyuki Yamamoto, Masataka Ikeda, Hiroaki Nagano, Ichiro Takemasa, Takeshi Naitoh, Norikazu Yamada, Mamoru Uemura, Hidetoshi Eguchi, Yoshihiro Kakeji, Ken Shirabe, Yuichiro Doki","doi":"10.1007/s00595-024-02969-w","DOIUrl":"10.1007/s00595-024-02969-w","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the current status of perioperative venous thromboembolism (VTE) prophylaxis in gastrointestinal surgery in Japan.</p><p><strong>Methods: </strong>We reviewed data on eight gastroenterological procedures from the Japanese National Clinical Database (NCD), accrued between 2018 and 2020. Patient characteristics, prophylactic methods, postoperative bleeding, cardiac arrest, and postoperative mortality rate within 30 days were retrieved.</p><p><strong>Results: </strong>Despite recommendations, approximately 30% of patients did not receive VTE prophylaxis, suggesting a lack of awareness. Pharmacological prophylaxis was associated with a higher incidence of VTE than mechanical or no prophylaxis for all procedures. Combined prophylaxis resulted in a lower incidence of VTE than pharmacological prophylaxis alone. Pharmacological prophylaxis was also associated with an increased incidence of bleeding events. The risk of cardiac arrest and death was higher in patients with pulmonary embolism (PE), but there was a trend toward lower mortality in the group that received pharmacological prophylaxis.</p><p><strong>Conclusion: </strong>Pharmacological prophylaxis for VTE was limited in reducing the incidence of VTE, but it may reduce the risk of death. Combining pharmacological and mechanical prophylaxis tended to be more effective for preventing VTE than either method alone. Conversely, pharmacological prophylaxis may increase the risk of bleeding.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"814-822"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A prospective study on the enhancement of surgical safety in robotic surgery: The BirdView camera system.","authors":"Yusuke Ogi, Taro Oshikiri, Hiroyuki Egi, Kei Ishimaru, Shigehiro Koga, Motohira Yoshida, Satoshi Kikuchi, Satoshi Akita, Hironori Matsumoto, Hiroki Sugishita","doi":"10.1007/s00595-024-02975-y","DOIUrl":"10.1007/s00595-024-02975-y","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the surgical safety and benefits of using the BirdView camera system with a wide field of view in robotic surgery for rectal cancer in a prospective clinical study.</p><p><strong>Methods: </strong>This study included 20 consecutive patients who underwent robotic surgery at our institution between the years 2022 and 2023. The primary endpoint was perioperative safety, which was defined as the occurrence of adverse events, including other organ injuries and malfunctions, caused by the BirdView camera system.</p><p><strong>Results: </strong>There were no injuries to any other organs caused by the console surgeon or assistant forceps during surgery. Surgical adverse events occurred in five cases (atelectasis, paralytic ileus, and anastomotic leakage) during the postoperative course. There were no cases of device failure or damage to the surrounding organs, including peritoneal heat damage.</p><p><strong>Conclusions: </strong>We believe that the BirdView system could be valuable in improving the safety of robotic surgery by enabling the observation of blind spots, thus preventing harm to other organs.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"746-753"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Learning curve of consolers and bedside surgeons fused robotic-assisted thoracoscopic segmentectomy: insights from the initial 100 cases.","authors":"Yuki Uno, Shinya Tane, Yugo Tanaka, Midori Takanashi, Takefumi Doi, Hiroyuki Ogawa, Daisuke Hokka, Yoshimasa Maniwa","doi":"10.1007/s00595-024-02957-0","DOIUrl":"10.1007/s00595-024-02957-0","url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the learning curve of segmentectomy using the \"fused surgery\" approach.</p><p><strong>Methods: </strong>We retrospectively collected data from 100 patients who underwent segmentectomy via fused robot-assisted thoracoscopy at our institution between September 2020 and February 2024. The learning curve was evaluated using the cumulative sum of the operative times in all cases and was analyzed separately for simple and complex segmentectomies.</p><p><strong>Results: </strong>After applying the cumulative sum method to all cases, we obtained a graph of the operative time that showed three well-differentiated phases: phase 1 (n = 23), the initial learning phase; phase 2 (n = 28), the increased competence phase; and phase 3 (n = 49), the highest skill phase. Comparing phases 1 and 2 with phase 3, we found significant differences in operative time (P < 0.001); however, no significant differences were observed in bleeding or rate of postoperative complications. We observed a significant reduction in operative time after 25 simple segmentectomies and 22 complex segmentectomies.</p><p><strong>Conclusions: </strong>The data suggested that the inflection point of the learning curve was achieved in 51 cases. Complex segmentectomy requires the same cases to achieve the same level of competence as simple segmentectomy.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"823-829"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New strategy of early surgery for infective endocarditis complicated by intracranial hemorrhage.","authors":"Shota Hasegawa, Hiroaki Takahashi, Katsuhiro Yamanaka, Kenji Okada","doi":"10.1007/s00595-024-02964-1","DOIUrl":"10.1007/s00595-024-02964-1","url":null,"abstract":"<p><strong>Purpose: </strong>Early surgery for infective endocarditis with intracranial hemorrhage can cause severe bleeding, which is correlated with an increased mortality. In 2005, we started using nafamostat mesilate and low-dose heparin as anticoagulants during cardiopulmonary bypass for early surgery. The outcomes of this strategy have been reviewed.</p><p><strong>Methods: </strong>All patients who underwent cardiac surgery for active infective endocarditis with intracranial hemorrhage between 2005 and 2023 were evaluated.</p><p><strong>Results: </strong>There were 23 consecutive patients (median age 62 years old). Ten patients (43%) had neurologic deficits. The indication for early surgery in most patients was the presence of mobile vegetation or existing embolic events (18 of 23, 78%). No complications were associated with cardiopulmonary bypass. The median interval between the diagnosis and surgery was two days. There was 1 early death (4%) due to sepsis. There was no exacerbation of intracranial hemorrhage. One patient had new ectopic microbleeds without deterioration of neurologic findings. One patient had a new-onset cerebral infarction with neurologic deficits. None of the patients exhibited neurologic deterioration. The median follow-up duration was 26 months. overall survival was 90.7% after 5 years.</p><p><strong>Conclusions: </strong>Our strategy of using nafamostat mesilate enabled us to safely perform early surgery in patients with intracranial hemorrhage without hemorrhage exacerbation.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"795-802"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perioperative changes in the quality of life and the impact of preoperative quality of life on the time to return to work after surgery among patients with colorectal cancer: a prospective, multicenter, cohort study.","authors":"Yusuke Fujita, Koya Hida, Tatsuto Nishigori, Shinya Hamasu, Tetsuya Shiota, Takatsugu Kan, Ryosuke Okamura, Yoshiro Itatani, Kazutaka Obama","doi":"10.1007/s00595-025-03012-2","DOIUrl":"10.1007/s00595-025-03012-2","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated perioperative changes in quality of life (QOL) and the impact of preoperative QOL on the time to return to work (RTW) after surgery in patients with colorectal cancer.</p><p><strong>Methods: </strong>Patients with clinical stage I-III colorectal cancer who were employed at the diagnosis and scheduled for curative surgery between 2019 and 2020 were prospectively enrolled at 7 hospitals in Japan. The patients' EORTC-QLQ-C30 scores and employment status were collected before and at 6 and 12 months after surgery and compared using a paired t test. The Kaplan-Meier method and multivariable Cox regression model were applied to examine the impact of preoperative QOL on the time to RTW.</p><p><strong>Results: </strong>A total of 127 patients were analyzed. Regarding financial difficulties, 48% of patients had low preoperative scores, which significantly improved at 6 (preoperatively: 21.7 vs 6 months: 11.3; p < 0.001) and 12 months (6 months: 11.3; 12 months: 7.9; p = 0.016) postoperatively. RTW was significantly delayed in patients with a low preoperative cognitive function (p = 0.039) and severe fatigue (p = 0.024). The adjusted hazard ratio was 0.73 for a low cognitive function and 0.62 for strong fatigue.</p><p><strong>Conclusion: </strong>Working patients with colorectal cancer experienced severe financial difficulties preoperatively, which decreased postoperatively. The preoperative cognitive function and fatigue affected the postoperative time to RTW.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"760-767"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for anastomotic leakage and long-term outcomes after laparoscopic right colectomy: a multicenter study in a Japanese rural area.","authors":"Rika Ono, Tetsuro Tominaga, Takashi Nonaka, Yuma Takamura, Kaido Oishi, Shintaro Hashimoto, Toshio Shiraishi, Keisuke Noda, Makoto Hisanaga, Akiko Fukuda, Masaaki Moriyama, Keizaburo Maruyama, Shoko Tei, Kazuhide Ishimaru, Keitaro Matsumoto","doi":"10.1007/s00595-025-03066-2","DOIUrl":"https://doi.org/10.1007/s00595-025-03066-2","url":null,"abstract":"<p><strong>Purpose: </strong>This study used a Japanese multicenter database to identify risk factors for anastomotic leakage (AL) and evaluate the long-term outcomes of patients who underwent laparoscopic right colectomy.</p><p><strong>Methods: </strong>The subjects of this retrospective review were 729 patients who underwent laparoscopic right colectomy. Clinical features were compared between patients who suffered AL (n = 33) and those who did not (n = 696).</p><p><strong>Results: </strong>Multivariate analysis identified pulmonary disease (odds ratio [OR] 6.681, 95% confidence interval [CI] 1.495-19.864; p = 0.012), steroid use (OR 10.930, 95%CI 6.131-14.783; p < 0.001), open conversion (OR 12.648, 95%CI 5.479-15.438; p < 0.001), and blood loss ≥ 25 ml (OR 3.260, 95%CI 1.407-7.553; p = 0.005) as independent prognostic factors for AL. The five-year recurrence-free survival (RFS) rates were 43.6% in the AL group and 80.3% in the non-AL group (p = 0.016), while the 5-year overall survival (OS) rates were 71.3% in the AL group and 85.8% in the non-AL group (p = 0.027). Multivariate analysis identified AL (HR 1.519, 95%CI 1.646-3.591; p = 0.037) as the only independent predictor of OS.</p><p><strong>Conclusions: </strong>Pulmonary disease, steroid use, and open conversion were identified as risk factors for AL in patients who underwent laparoscopic right colectomy. AL was associated with poor prognosis. Achievement of good short- and long-term results will require careful perioperative management of patients with these risk factors.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-05-28DOI: 10.1007/s00595-025-03065-3
Alessia Fassari, Vito De Blasi, Edoardo Rosso
{"title":"How to do it: specimen splitting and lifting maneuver in robotic radical distal pancreatosplenectomy for borderline pancreatic body tumors.","authors":"Alessia Fassari, Vito De Blasi, Edoardo Rosso","doi":"10.1007/s00595-025-03065-3","DOIUrl":"https://doi.org/10.1007/s00595-025-03065-3","url":null,"abstract":"<p><p>Robotic radical pancreatosplenectomy is an advanced minimally invasive procedure for left-sided pancreatic cancer, especially for borderline tumors with suspected vascular involvement. Building on the oncologic principles of Radical Antegrade Modular Pancreatosplenectomy (RAMPS), we describe technical refinements tailored to the robotic setting. Specifically, our approach begins with early pancreatic transection to facilitate vascular exposure of bulky tumors, unlike with the classical RAMPS sequence, while preserving key principles such as posterior dissection and extended lymphadenectomy. Two cases are presented: one that required venous divestment and one that involved reconstruction of the splenomesenteric confluence using a bovine pericardial patch. The specimen-splitting and lifting maneuver enhances vascular control and visualization, enabling safer dissection and resection. Both procedures were completed robotically without conversion, achieving R0 margins, followed by uneventful recovery. While this technique diverges from Strasberg's original description, it aligns with its oncologic intent and reflects evolving surgical adaptations. Prospective data collection is ongoing to assess the long-term outcomes of complex cases.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using the comprehensive complication index to assess the impact of Global Leadership Initiative on Malnutrition (GLIM)-defined malnutrition on postoperative complications after resection for biliary tract cancer.","authors":"Yuki Okazoe, Hiroaki Yanagimoto, Daisuke Tsugawa, Masayuki Akita, Takuya Mizumoto, Toshihiko Yoshida, Shinichi So, Jun Ishida, Takeshi Urade, Yoshihide Nanno, Kenji Fukushima, Hidetoshi Gon, Shohei Komatsu, Sadaki Asari, Hirochika Toyama, Masahiro Kido, Takumi Fukumoto","doi":"10.1007/s00595-025-03051-9","DOIUrl":"https://doi.org/10.1007/s00595-025-03051-9","url":null,"abstract":"<p><strong>Purpose: </strong>The Global Leadership Initiative on Malnutrition (GLIM) criteria, proposed in 2018, provide universal diagnostic standards for malnutrition, a known risk factor for postoperative complications in patients with various cancers. However, its impact on surgery for biliary tract cancer (BTC) remains unclear. This study evaluates the relationship between GLIM-defined malnutrition and postoperative complications after resection for BTC.</p><p><strong>Methods: </strong>The subjects of this retrospective study were patients who underwent pancreaticoduodenectomy or major hepatectomy with extrahepatic bile duct resection for BTC between January, 2013 and December, 2021. The comprehensive complication index (CCI), an indicator of postoperative complications, was calculated based on the total number and severity of postoperative complications.</p><p><strong>Results: </strong>GLIM-defined malnutrition was diagnosed in143 (71.1%) of the total 201 patients. The median CCI was significantly higher in the GLIM-defined malnutrition group than in the non-malnutrition group (37.2 vs. 28.3; P < 0.001). Multivariate logistic regression analysis revealed that GLIM-defined malnutrition (odds ratio 2.87 [95% confidence interval 1.38-5.96], P = 0.005) and intraoperative blood loss > 1,000 mL (odds ratio 3.77 [95% confidence interval 1.06-13.47], P = 0.041) were independent predictors of high morbidity (CCI ≥ 37.1).</p><p><strong>Conclusion: </strong>Preoperative GLIM-defined malnutrition was closely associated with increased postoperative complications in patients who underwent resection for BTC.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oncological merits of intracorporeal anastomosis versus extracorporeal anastomosis for right-sided colon cancer.","authors":"Katsuya Watanabe, Taro Oshikiri, Kyosuke Habu, Yusuke Ogi, Hiroki Sugishita, Satoshi Akita, Motohira Yoshida, Shigehiro Koga, Kei Ishimaru, Yuji Watanabe","doi":"10.1007/s00595-025-03054-6","DOIUrl":"https://doi.org/10.1007/s00595-025-03054-6","url":null,"abstract":"<p><strong>Purpose: </strong>The incidence of colorectal cancer (CRC) is increasing worldwide. Surgical resection is the primary treatment for localized cases with the aim of complete tumor removal and adequate lymph node dissection. Intracorporeal anastomosis (IA) has gained popularity in colorectal surgery; however, its oncological benefits over extracorporeal anastomosis (EA) remain unclear.</p><p><strong>Methods: </strong>This retrospective study at Ehime University Hospital included 118 right-sided colon cancer patients (54 IA and 64 EA) treated between 2018 and 2023. Outcomes such as distal margin (DM) length and number of lymph nodes dissected were assessed.</p><p><strong>Results: </strong>In the IA group, the DM was significantly longer (117.9 ± 49.5 mm vs. 78.2 ± 30.1 mm, p < 0.001) and more lymph nodes were harvested (22.2 ± 10.0 vs. 18.2 ± 9.9, p = 0.031). A multivariate analysis identified IA as an independent factor for DM > 10 cm (odds ratio [OR] = 0.25, p = 0.001) and > 12 dissected lymph nodes (OR = 0.15, p = 0.006). Patients with IA resumed ingestion and defecation sooner, with shorter hospital stays.</p><p><strong>Conclusions: </strong>IA provides significant advantages for DM length and lymph node dissection, suggesting that it may be preferable for right-sided colon cancer surgery.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}