{"title":"Use of a zipline skin closure device in gastroenterological surgery: a multicenter randomized controlled trial assessing wound infection incidence, operation time, and cosmesis.","authors":"Ayato Obana, Takuya Minagawa, Ayako Shimada, Junko Mukohyama, Yuki Hirano, Sojun Hoshimoto, Takashi Oyama, Tsuruta Masashi, Takashi Ishida, Takuya Tamura, Kyoichi Matsuzaki, Mitsuru Takaku, Hirotoshi Ohara, Motoi Koyama, Masahiro Shinoda, Tatsushi Suwa, Osamu Itano","doi":"10.1007/s00595-025-03043-9","DOIUrl":"10.1007/s00595-025-03043-9","url":null,"abstract":"<p><p>Subcuticular sutures, which are effective and cosmetically advantageous in gastroenterological surgery, are time-consuming and heavily dependent on the surgeon's technical expertise. This study aims to evaluate whether Zipline skin closure could be an alternative to subcuticular sutures in gastroenterological surgery. A multicenter randomized controlled trial (UMIN000048169) was conducted on 76 patients who underwent elective gastroenterological surgery. The patients were randomized to either the Zipline group (N = 35) or the subcuticular suture group (N = 41). Primary outcomes included skin closure time and secondary outcomes included postoperative wound complications and cosmetic results, assessed 6 months post-surgery, using the Stony Book Scar Evaluation Scale (SBSES). The Zipline group demonstrated significantly shorter closure times than the suture group (median: 438 s [406-526] vs. 575 s [537-638]; p = 0.003). This difference was more pronounced for incisions > 55 mm (median:399 s [307-533] vs. 605 s [493-736]; p = 0.001). No significant differences were observed in wound infection rates (5.7% vs. 2.4%; p = 0.46) or SBSES scores (median: 4.0 [4.0-5.0] vs. 4.0 [3.0-5.0; p = 0.82) between the two groups. The Zipline device reduced the skin closure time in gastroenterological surgery significantly, particularly for large incisions, without compromising wound healing or cosmetic outcomes. These findings suggest that the Zipline system may be a viable alternative to traditional subcuticular sutures in gastroenterological procedures, potentially promoting operating room efficiency without compromising surgical quality or patient outcomes.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1488-1496"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Living donor liver transplantation using ABO-incompatible grafts for chronic and acute liver failure.","authors":"Toru Ikegami, Masashi Tsunematsu, Kenei Furukawa, Shinji Onda, Michinori Matsumoto, Yoshihiro Shirai, Koichiro Haruki","doi":"10.1007/s00595-025-03100-3","DOIUrl":"10.1007/s00595-025-03100-3","url":null,"abstract":"<p><p>The introduction of rituximab, an anti-CD20 antibody, has changed the treatment strategies and outcomes for ABO-incompatible living donor liver transplantation (ABOi-LDLT) dramatically. Rituximab targets the CD20-positive B-cells that would differentiate into plasma cells, producing antibodies against A or B antigen-expressing cells and causing microvascular multiple thrombosis and graft necrosis or diffuse bile-duct necrosis. Now, the universal desensitization of the ABOi combination between the donor and recipient is performed by rituximab, and ABOi-LDLT has become the treatment of choice for end-stage liver disease. However, because rituximab takes 1-3 weeks to mediate its effects, complicated strategies are necessary to perform ABOi-LDLT for acute liver failure. For example, high-dose intravenous immunoglobulin (IVIG) or bortezomib may be used to alleviate the elevation of isoagglutinin titers. The diagnosis and treatment of antibody-mediated rejection (AMR) remain challenging. Treatment options include plasma exchange, high-dose IVIG, and bortezomib, but the optimal strategies have not been identified. In this review, we discuss standard ABOi-LDLT for chronic liver disease, ABOi-LDLT for acute liver failure, and the diagnosis and treatment of AMR.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1347-1352"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pleurodesis using 50% glucose solution for air leak after pulmonary resection: a multi-center retrospective study.","authors":"Ryosuke Tokuda, Satoru Okada, Yasuo Ueshima, Satoshi Ikebe, Masanori Shimomura, Shunta Ishihara, Tatsuo Furuya, Kenji Kameyama, Masayoshi Inoue","doi":"10.1007/s00595-025-03041-x","DOIUrl":"10.1007/s00595-025-03041-x","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the usefulness of and predictive factors for pleurodesis using 50% glucose solution to treat air leak after pulmonary resection.</p><p><strong>Methods: </strong>The subjects of this retrospective study were 70 patients from three Japanese institutions, who were treated with 50% glucose solution for postoperative air leak between April, 2015 and March, 2023. Air leak was monitored using a digital drainage system. We analyzed the patient characteristics, surgical details, and outcomes. Successful pleurodesis was defined as control of the air leak within two attempts and no recurrence within 1 month after drain removal. Predictors of success were identified using multivariable logistic regression.</p><p><strong>Results: </strong>Pleurodesis with 50% glucose solution treated air leak successfully in 58 patients (83%), with a median time from resection to pleurodesis of 4 days. Air leak control was achieved within 2 days in 93% of these patients. Air leak volume < 300 mL/min before pleurodesis and an air space rate < 10% calculated on chest radiograph were independent predictors of success. The success rate for patients with both or none of these factors was 97% and 29%, respectively. No life-threatening complications were observed.</p><p><strong>Conclusions: </strong>Pleurodesis using 50% glucose solution could be useful for managing postoperative air leak, especially in patients with an air leak volume < 300 mL/min and an air space rate < 10%.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1436-1445"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-10-01Epub Date: 2025-05-07DOI: 10.1007/s00595-025-03055-5
Masahisa Ohkuma, Yasuhiro Takano, Keisuke Goto, Atsuko Okamoto, Muneyuki Koyama, Tadashi Abe, Takafumi Nakano, Yasuhiro Takeda, Makoto Kosuge, Ken Eto
{"title":"Significance of Naples prognostic score for postoperative complications after colorectal cancer surgery.","authors":"Masahisa Ohkuma, Yasuhiro Takano, Keisuke Goto, Atsuko Okamoto, Muneyuki Koyama, Tadashi Abe, Takafumi Nakano, Yasuhiro Takeda, Makoto Kosuge, Ken Eto","doi":"10.1007/s00595-025-03055-5","DOIUrl":"10.1007/s00595-025-03055-5","url":null,"abstract":"<p><strong>Purpose: </strong>The Naples prognostic score (NPS) is a sensitive scoring system that reflects both inflammatory and nutritional status. This study examined the significance of NPS in predicting postoperative complications following colorectal cancer surgery.</p><p><strong>Methods: </strong>The present study included data from 443 patients who underwent curative resection for colorectal cancer. The patients were classified into low NPS (score 0-2) and high NPS (score 3-4) groups. We retrospectively investigated the relationship between NPS and postoperative complications (Clavien-Dindo classification ≥ II).</p><p><strong>Results: </strong>Among all patients, 57 (13%) developed postoperative complications. A total of 340 patients (77%) were categorized into the low NPS group and 103 (23%) were categorized into the high NPS group. A multivariate analysis identified that high NPS (P < 0.001), tumor location in the rectum (P = 0.025), longer operation time (P = 0.027), and greater blood loss (P = 0.004) were independent risk factors for postoperative complications. Furthermore, high NPS was significantly associated with older age (P < 0.001), higher American Society of Anesthesiologists physical status score (P = 0.029), advanced T stage (P < 0.001), N stage (P = 0.036), and longer length of hospital stay (P < 0.010).</p><p><strong>Conclusions: </strong>NPS is a strong predictor of poor outcomes in patients undergoing curative resection for colorectal cancer, suggesting the importance of systemic inflammation and the nutritional status.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1481-1487"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transanal total mesorectal excision for locally advanced rectal cancer following neoadjuvant chemoradiotherapy.","authors":"Takeru Matsuda, Kimihiro Yamashita, Hiroshi Hasegawa, Ryuichiro Sawada, Yasufumi Koterazawa, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Shingo Kanaji, Yoshihiro Kakeji","doi":"10.1007/s00595-025-03042-w","DOIUrl":"10.1007/s00595-025-03042-w","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the clinical impact of transanal total mesorectal excision (TaTME) for locally advanced rectal cancer after neoadjuvant chemoradiotherapy (NACRT).</p><p><strong>Methods: </strong>This retrospective study included 91 patients undergoing surgery for rectal cancer after NACRT between 2011 and 2022. Among them, 24, 22, and 45 patients underwent open (Open), conventional laparoscopic (Lap), and TaTME surgeries, respectively. We compared their clinical outcomes.</p><p><strong>Results: </strong>Operative time, blood loss, transfusion, morbidity, and hospital stay were significantly lower in the TaTME group than in the Open or Lap groups. The multivariate regression analyses identified only the TaTME approach as a significant factor for reducing morbidity. Both 3 yrear relapse-free survival (RFS) and local recurrence-free survival (LRFS) were significantly better in the TaTME group than in the Open or Lap groups (3 yr RFS: 94.7%, 80.4%, and 66.7%, and 3 yr LRFS: 100%, 90.5%, and 82.2% for the TaTME, Lap, and Open groups, respectively). Multivariate analyses of potential risk factors for recurrence identified body mass index, combined resection, and pathological stage, but not the TaTME approach, as significant predictors of recurrence.</p><p><strong>Conclusion: </strong>TaTME reduced morbidity significantly in patients with locally advanced rectal cancer undergoing NACRT, compared with open or laparoscopic surgery.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1373-1382"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temporary atypical vascular ultrasound-guided central venous approach in patients with venous occlusion.","authors":"Naonori Kawakubo, Junnosuke Maniwa, Yoshiaki Takahashi, Takuya Kondo, Atsuhisa Fukuta, Koichiro Yoshimaru, Kouji Nagata, Junko Miyata, Toshiharu Matsuura, Tatsuro Tajiri","doi":"10.1007/s00595-025-03056-4","DOIUrl":"10.1007/s00595-025-03056-4","url":null,"abstract":"<p><p>This study presents an innovative ultrasound-guided technique for central venous access in patients with venous occlusion, particularly in those requiring long-term parenteral nutrition (TPN). Conventional access points often become occluded, necessitating alternative methods for approaching the central vein. A retrospective review of three patients with venous occlusion due to prolonged TPN use was conducted at our institution. The procedure involved ultrasound-guided puncture of atypical vessels, such as the internal mammary, anterior jugular, or innominate veins, using the Seldinger or introducer technique depending on vessel size. All catheters were successfully placed with minimal complications, allowing for continued TPN. The study concluded that ultrasound-guided access to atypical vessels offers a safer and less invasive alternative to central venous access in complex cases, particularly in adolescent and young adult patients.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"1506-1510"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robotic para-aortic lymph node dissection via the left renal vein as the starting point.","authors":"Hiroyuki Sagawa, Kohei Fujita, Sunao Ito, Reo Sato, Shuji Takiguchi","doi":"10.1007/s00595-025-03141-8","DOIUrl":"https://doi.org/10.1007/s00595-025-03141-8","url":null,"abstract":"<p><p>Preoperative chemotherapy combined with gastrectomy and radical surgery may be useful in patients with gastric cancer and metastasis-positive para-aortic lymph nodes. Although robotic surgery is considered useful in difficult cases because it provides highly magnified three-dimensional high-definition images of anatomical views and precise techniques, a meticulous approach for para-aortic lymph node dissection (PALND) is important. We typically perform PALND via the left renal vein at our institution. Robotic PALND was performed in six patients from April 2018 to July 2024. The median total operative time and volume of blood loss were 552 (271-634) min and 316 (75-771) mL, respectively. The time required for dissection of No. 16b1-int and No. 16a2-lat was 68 (65-103) min and approximately 30 min, respectively. All six patients underwent rapid postoperative treatment, including postoperative chemotherapy. A clear understanding of the relevant anatomy, beginning with the left renal vein, should result in a safe and reliable robotic surgical approach for PALND.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of sequential perioperative chemotherapy for high-risk colorectal liver metastases.","authors":"Kosuke Kobayashi, Yoshihiro Ono, Atsushi Oba, Hiroki Osumi, Eiji Shinozaki, Hiromichi Ito, Takashi Akiyoshi, Kensei Yamaguchi, Yosuke Fukunaga, Yosuke Inoue, Yu Takahashi","doi":"10.1007/s00595-025-03127-6","DOIUrl":"https://doi.org/10.1007/s00595-025-03127-6","url":null,"abstract":"<p><strong>Background: </strong>The impact of perioperative chemotherapy, including neoadjuvant chemotherapy (NAC) and adjuvant chemotherapy (AC), given for resectable colorectal liver metastasis (CLM) remains unclear. This study evaluates the optimal strategy for managing high-risk CLM.</p><p><strong>Methods: </strong>The subjects of this retrospective study were patients who underwent liver resection for initially resectable CLM between 2006 and 2021. High-risk status was defined by four or more metastases, a tumor size ≥ 5 cm, or the presence of resectable extrahepatic disease. Among 363 eligible patients, 293 received NAC and 70 underwent upfront surgery. Propensity score matching (PSM) created balanced groups of 70 each.</p><p><strong>Results: </strong>Among the patients who received NAC, seven did not undergo resection because they had disease progression. Intention-to-treat analysis revealed significantly longer median progression-free survival (PFS) (1.1 vs. 0.6 years, p < 0.001) and overall survival (OS) (5.2 vs. 4.3 years, p = 0.044) in the NAC group. Matched analysis confirmed superior PFS (1.2 vs. 0.6 years, p = 0.004) and a favorable OS trend (5.4 vs. 4.3 years, p = 0.164). Completion of the perioperative sequence of NAC, surgery, and AC was associated with the most favorable outcomes.</p><p><strong>Conclusion: </strong>Achieving a sequential strategy of NAC, surgery, and AC may improve the long-term survival of patients with high-risk CLM, supporting its potential as a standard treatment strategy.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SARS-CoV-2 infection in lung transplant recipients: a single-center retrospective study in Japan.","authors":"Mikihiro Kohno, Akihiro Ohsumi, Jumpei Kimura, Mamoru Takahashi, Satona Tanaka, Yojiro Yutaka, Daisuke Nakajima, Miki Nagao, Hiroshi Date","doi":"10.1007/s00595-025-03136-5","DOIUrl":"https://doi.org/10.1007/s00595-025-03136-5","url":null,"abstract":"<p><strong>Purpose: </strong>Lung transplant (LTx) recipients are at a higher risk of infection and mortality due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The course of coronavirus disease 2019 (COVID-19) in Japanese LTx recipients remains unknown. This study aimed to clarify the incidence, outcomes, and clinical characteristics of COVID-19 in LTx recipients in Japan over a 3-year period.</p><p><strong>Methods: </strong>This single-center retrospective study enrolled all LTx recipients who underwent LTx at Kyoto University Hospital between June 2008 and December 2022 and who were followed up during the COVID-19 pandemic from March 2020 to June 2023.</p><p><strong>Results: </strong>Among 230 LTx recipients, 64 (27.8%) developed SARS-CoV-2 infection and one (1.6%) died due to COVID-19. No significant differences in baseline characteristics, except for hypertension, were observed between the LTx recipients with and without COVID-19. Disease severity decreased as variants of concern transitioned but remained high even after 2022. Unilateral LTx, advanced age, and diabetes mellitus were associated with COVID-19 severity.</p><p><strong>Conclusions: </strong>The incidence of COVID-19 in LTx recipients was similar to that in the general Japanese population, whereas the disease severity in LTx recipients remained high even after the Omicron era. Continuous development of preventive and early therapeutic interventions is required for these vulnerable groups.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robotic partial splenectomy: a new standardized approach.","authors":"Mohamed Amine Tormane, Ambroise Ravenet, Francesco Carenini, Alexandre Lecis, Tarek Kellil, Tullio Piardi","doi":"10.1007/s00595-025-03140-9","DOIUrl":"https://doi.org/10.1007/s00595-025-03140-9","url":null,"abstract":"<p><p>The treatment of benign splenic diseases is trending toward a conservative approach, especially for young patients, due to the importance of preserving as much splenic parenchyma as possible. Minimally invasive partial splenectomy (PS), which has become the gold standard for managing benign splenic conditions, is generally associated with low morbidity and near-zero mortality. Herein, we describe a standardized and safe technique to perform this procedure. This new approach combines preoperative selective distal embolization of the splenic artery with indocyanine green (ICG)-guided robotic partial splenectomy using the technique of negative staining as applied in liver surgery.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}