Significance of Naples prognostic score for postoperative complications after colorectal cancer surgery.

IF 1.6 4区医学 Q2 SURGERY

Surgery Today Pub Date : 2025-10-01 Epub Date: 2025-05-07 DOI:10.1007/s00595-025-03055-5

Masahisa Ohkuma, Yasuhiro Takano, Keisuke Goto, Atsuko Okamoto, Muneyuki Koyama, Tadashi Abe, Takafumi Nakano, Yasuhiro Takeda, Makoto Kosuge, Ken Eto

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引用次数: 0

Abstract

Purpose: The Naples prognostic score (NPS) is a sensitive scoring system that reflects both inflammatory and nutritional status. This study examined the significance of NPS in predicting postoperative complications following colorectal cancer surgery.

Methods: The present study included data from 443 patients who underwent curative resection for colorectal cancer. The patients were classified into low NPS (score 0-2) and high NPS (score 3-4) groups. We retrospectively investigated the relationship between NPS and postoperative complications (Clavien-Dindo classification ≥ II).

Results: Among all patients, 57 (13%) developed postoperative complications. A total of 340 patients (77%) were categorized into the low NPS group and 103 (23%) were categorized into the high NPS group. A multivariate analysis identified that high NPS (P < 0.001), tumor location in the rectum (P = 0.025), longer operation time (P = 0.027), and greater blood loss (P = 0.004) were independent risk factors for postoperative complications. Furthermore, high NPS was significantly associated with older age (P < 0.001), higher American Society of Anesthesiologists physical status score (P = 0.029), advanced T stage (P < 0.001), N stage (P = 0.036), and longer length of hospital stay (P < 0.010).

Conclusions: NPS is a strong predictor of poor outcomes in patients undergoing curative resection for colorectal cancer, suggesting the importance of systemic inflammation and the nutritional status.

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那不勒斯预后评分对结直肠癌术后并发症的意义。

目的：那不勒斯预后评分（NPS）是一个敏感的评分系统，反映炎症和营养状况。本研究探讨了NPS在预测结直肠癌术后并发症中的意义。方法：本研究纳入了443例结肠直肠癌根治性切除术患者的资料。将患者分为低NPS（0 ~ 2分）组和高NPS（3 ~ 4分）组。回顾性研究NPS与术后并发症的关系（Clavien-Dindo分级≥II）。结果：57例（13%）患者出现术后并发症。低NPS组340例（77%），高NPS组103例（23%）。结论：NPS是结直肠癌根治性切除患者预后不良的一个强有力的预测因子，提示全身性炎症和营养状况的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgery Today 医学-外科

CiteScore

4.90

自引率

4.00%

发文量

208

审稿时长

1 months

期刊介绍： Surgery Today is the official journal of the Japan Surgical Society. The main purpose of the journal is to provide a place for the publication of high-quality papers documenting recent advances and new developments in all fields of surgery, both clinical and experimental. The journal welcomes original papers, review articles, and short communications, as well as short technical reports("How to do it"). The "How to do it" section will includes short articles on methods or techniques recommended for practical surgery. Papers submitted to the journal are reviewed by an international editorial board. Field of interest: All fields of surgery.