Surgery Today最新文献_第4页

Comments on the published article: "periodontitis as a potential predisposing factor for gallstone cholecystitis''. 对已发表文章“牙周炎作为胆囊炎的潜在诱发因素”的评论。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-07-09 DOI: 10.1007/s00595-026-03401-1

Yazgı Köy, Özge Keleş, M Burak Kamburoğlu, Saffet Çınar

引用次数: 0

A learning curve analysis of resident-performed laparoscopic transabdominal preperitoneal inguinal hernia repair and the impact of the operative interval. 住院医师腹腔镜经腹腹膜前腹股沟疝修补术的学习曲线分析及手术间隔的影响。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-07-03 DOI: 10.1007/s00595-026-03394-x

Shuhei Baba, Tomohiro Iguchi, Takafumi Yukaya, Yoshihiro Nagao, Mayumi Ishida, Takuya Matsumoto, Hideaki Uchiyama

{"title":"A learning curve analysis of resident-performed laparoscopic transabdominal preperitoneal inguinal hernia repair and the impact of the operative interval.","authors":"Shuhei Baba, Tomohiro Iguchi, Takafumi Yukaya, Yoshihiro Nagao, Mayumi Ishida, Takuya Matsumoto, Hideaki Uchiyama","doi":"10.1007/s00595-026-03394-x","DOIUrl":"10.1007/s00595-026-03394-x","url":null,"abstract":"Purpose: Laparoscopic transabdominal preperitoneal inguinal hernia repair (TAPP) is useful for resident training. However, the association between the operative interval and skill acquisition remains unclear. We evaluated the learning curve of resident-performed TAPP and explored the association between the operative interval and operative time changes.Methods: We retrospectively analyzed 67 consecutive TAPP cases performed by a single surgical resident. A cumulative sum (CUSUM) analysis was based on the adjusted operative time, with bilateral cases weighted by 0.6. Breakpoints were estimated using segmented regression, and the relationship between the operative interval and the change in adjusted operative time between consecutive cases (ΔTime) was assessed using exploratory analyses.Results: A CUSUM analysis estimated breakpoints at 16.0 (95% CI, 13.7-18.3) and 38.1 (95% CI, 36.5-39.7) cases. BMI showed a weak negative correlation with operative duration. The adjusted operative time decreased across the learning, proficiency, and competency phases. Exploratory LOESS curves suggested a possible non-linear relationship between operative interval and ΔTime, with 8-14-day intervals showing a tendency toward a greater reduction during early phases. However, the differences among the interval groups were not significant.Conclusion: Resident-performed TAPP exhibited a three-phase learning curve. Case selection and operative interval may be associated with operative time changes, although these findings remain exploratory.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2494-2500"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histological treatment response to neoadjuvant chemotherapy predicts the survival outcomes of patients with resectable pancreatic cancer: validation of the Japan Pancreas Society grading system. 对新辅助化疗的组织学治疗反应预测可切除胰腺癌患者的生存结果：日本胰腺学会分级系统的验证。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-06-23 DOI: 10.1007/s00595-026-03325-w

Daisuke Douchi, Mika Ando, Yuichiro Umino, Hideaki Sato, Mitsuhiro Shimura, Koetsu Inoue, Masahiro Iseki, Shuichi Aoki, Keigo Murakami, Takayuki Miura, Shimpei Maeda, Masaharu Ishida, Masamichi Mizuma, Atsushi Masamune, Toru Furukawa, Michiaki Unno

{"title":"Histological treatment response to neoadjuvant chemotherapy predicts the survival outcomes of patients with resectable pancreatic cancer: validation of the Japan Pancreas Society grading system.","authors":"Daisuke Douchi, Mika Ando, Yuichiro Umino, Hideaki Sato, Mitsuhiro Shimura, Koetsu Inoue, Masahiro Iseki, Shuichi Aoki, Keigo Murakami, Takayuki Miura, Shimpei Maeda, Masaharu Ishida, Masamichi Mizuma, Atsushi Masamune, Toru Furukawa, Michiaki Unno","doi":"10.1007/s00595-026-03325-w","DOIUrl":"10.1007/s00595-026-03325-w","url":null,"abstract":"Purpose: To validate the prognostic value of histological treatment response, assessed using the Japan Pancreas Society (JPS) grading system, in patients with resectable pancreatic ductal adenocarcinoma (PDAC) treated with neoadjuvant chemotherapy (NAC) followed by surgical resection.Methods: We analyzed, retrospectively, data from 117 consecutive patients who underwent NAC and curative-intent PDAC resection at Tohoku University Hospital between January 2010 and December 2022. Histological responses were graded using the JPS system. Survival analyses were conducted using Kaplan-Meier estimation and Cox proportional hazards modeling.Results: Histological Grade 1a, 1b, 2, 3, and 4 responses were observed in 47 (40.2%), 42 (35.9%), 21 (17.9%), 6 (5.1%), and 1 (0.9%) patients, respectively. Patients with a Grade ≥ 2 response had significantly longer overall survival (OS) and significantly higher R0 resection rates than those with Grade 1a or 1b responses (median OS: 118.7 vs. 46.6 months, p = 0.037; 100% vs. 82.0%, p = 0.01). In a multivariable Cox regression model including RECIST progression status and baseline covariates, JPS Grade ≥ 2 remained significantly associated with better OS (adjusted HR 0.48; 95% CI 0.24-0.96; p = 0.039).Conclusion: Substantial histological response (JPS Grade ≥ 2) after NAC is strongly associated with improved OS and higher R0 resection rates in patients with resectable PDAC. The JPS grading system provides a basis for clinically meaningful prognostic stratification.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2406-2419"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13558277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing axillary surgery for patients with clinically node-negative and node-positive breast cancer. 临床淋巴结阴性和淋巴结阳性乳腺癌患者腋窝手术的优化。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-06-06 DOI: 10.1007/s00595-026-03342-9

Shigeru Imoto, Akiko Matsumoto, Rikiya Nakamura, Norikazu Masuda, Hiroyuki Yasojima, Tatsuya Onishi, Shigeki Minami, Sayaka Kuba, Noriaki Wada, Hiromitsu Jinno, Takahiro Nakayama, Tomohiko Aihara

{"title":"Optimizing axillary surgery for patients with clinically node-negative and node-positive breast cancer.","authors":"Shigeru Imoto, Akiko Matsumoto, Rikiya Nakamura, Norikazu Masuda, Hiroyuki Yasojima, Tatsuya Onishi, Shigeki Minami, Sayaka Kuba, Noriaki Wada, Hiromitsu Jinno, Takahiro Nakayama, Tomohiko Aihara","doi":"10.1007/s00595-026-03342-9","DOIUrl":"10.1007/s00595-026-03342-9","url":null,"abstract":"It is important that axillary surgery is optimized for de-escalation in the era of sentinel lymph node biopsy for early breast cancer. Several randomized trials of clinically node-negative breast cancer have demonstrated the non-inferiority of regional lymph node recurrence and distant metastasis in women aged ≥ 50 years with small tumors of the luminal subtype who did not undergo axillary surgery compared with those who underwent sentinel lymph node biopsy. Tailored axillary surgery has been attempted to personalize axillary management in patients with clinically node-positive breast cancer treated with neoadjuvant chemotherapy. Image-guided localization, such as clipping, has been shown to accurately diagnose lymph node involvement and reduce the rate of false negatives for sentinel lymph node biopsy. This technique also reduces regional lymph node recurrence, although regional nodal irradiation and adjuvant therapy are usually required for this purpose. In this review, we aimed to facilitate the optimization of axillary surgery for patients with clinically node-negative and node-positive breast cancer by discussing the findings of randomized trials and our own experiences at the Japanese Society for Sentinel Node Navigation Surgery.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2131-2139"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148176728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated use of artificial intelligence-associated vocabulary in Japanese surgical journals after 2023. 2023年后，日本外科期刊加速使用人工智能相关词汇。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-07-02 DOI: 10.1007/s00595-026-03383-0

Sota Nakamura, Kazuhiro Tada, Yo-Ichi Yamashita, Naotaka Inomata, Kazuhito Sakata, Kensaku Ito, Yosuke Kuroda, Fumitaka Yoshizumi, Hidenori Kouso, Kentaro Iwaki, Shoji Hiroshige, Hideya Takeuchi, Kengo Fukuzawa, Tomoharu Yoshizumi

{"title":"Accelerated use of artificial intelligence-associated vocabulary in Japanese surgical journals after 2023.","authors":"Sota Nakamura, Kazuhiro Tada, Yo-Ichi Yamashita, Naotaka Inomata, Kazuhito Sakata, Kensaku Ito, Yosuke Kuroda, Fumitaka Yoshizumi, Hidenori Kouso, Kentaro Iwaki, Shoji Hiroshige, Hideya Takeuchi, Kengo Fukuzawa, Tomoharu Yoshizumi","doi":"10.1007/s00595-026-03383-0","DOIUrl":"10.1007/s00595-026-03383-0","url":null,"abstract":"Purpose: The increased use of artificial intelligence (AI)-based writing tools may influence academic writing styles. This study aimed to evaluate changes in writing styles in Japanese surgical journals using quantitative time-series analysis.Methods: We analyzed articles published between 2015 and 2025 in Surgery Today and Surgical Case Reports. The writing style was quantified using predefined lexical sets for rare and common AI-related words and promotional words. The word density was calculated for each article separately. We conducted interrupted time-series analyses with 2023 as the intervention year. Observed post-2023 values were compared with the expected values based on pre-2023 trends.Results: Rare-word density showed a marked post-2023 increase, with a significant change in slope (β = 1.05 per year, 95% CI: 1.01-1.10, p < 0.001). The common-word density also increased after 2023 (β = 0.48, 95% CI: 0.46-0.51; p < 0.001). Promotional word density showed a smaller but statistically significant increase in the post-2023 slope (β = 0.34, 95% CI: 0.24-0.44; p < 0.001). For all three measures, the observed post-2023 values exceeded the expected values that were extrapolated from the pre-2023 trends.Conclusion: Post-2023, the increase in AI-associated lexical marker use in Japanese surgical journals showed accelerated growth compared to the expected long-term trends.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2478-2485"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative liver function trajectories and risk factors after hepatectomy for hepatocellular carcinoma. 肝细胞癌肝切除术后肝功能轨迹及危险因素。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-06-19 DOI: 10.1007/s00595-026-03331-y

Masaki Omori, Shohei Komatsu, Motochika Hamanaka, Masahiro Kido, Hidetoshi Gon, Kenji Fukushima, Takeshi Urade, Toshihiko Yoshida, Keisuke Arai, Dongha Lee, Masayuki Akita, Takuya Mizumoto, Jun Ishida, Yoshihide Nanno, Hiroaki Yanagimoto, Takumi Fukumoto

{"title":"Postoperative liver function trajectories and risk factors after hepatectomy for hepatocellular carcinoma.","authors":"Masaki Omori, Shohei Komatsu, Motochika Hamanaka, Masahiro Kido, Hidetoshi Gon, Kenji Fukushima, Takeshi Urade, Toshihiko Yoshida, Keisuke Arai, Dongha Lee, Masayuki Akita, Takuya Mizumoto, Jun Ishida, Yoshihide Nanno, Hiroaki Yanagimoto, Takumi Fukumoto","doi":"10.1007/s00595-026-03331-y","DOIUrl":"10.1007/s00595-026-03331-y","url":null,"abstract":"Purpose: Hepatectomy is a curative treatment for hepatocellular carcinoma (HCC) but deteriorating postoperative liver function can limit its benefits, especially for patients with borderline resectable (BR) HCC. We evaluated postoperative liver function trajectories and their impact on long-term survival.Methods: The subjects of this retrospective analysis were 790 patients who underwent initial curative hepatectomy, stratified by resectability (R, BR1, BR2) and modified albumin-bilirubin (mALBI) grade. Liver function was assessed via ALBI scores pre- and postoperatively. Deterioration was defined as an ALBI score ratio < 0.9.Results: Median overall survival (OS) differed significantly, being 109.9, 54.4, and 40.4 months for the R, BR1, and BR2 groups, respectively (p < 0.001). While functional status at POD 90 influenced recurrence-free survival, deterioration at POD 180 was identified as a robust independent predictor of OS (HR 1.53, p = 0.005). Notably, no single preoperative or perioperative factor was a significant predictor of this long-term functional decline at POD 180. Postoperative recovery was heterogeneous, with 47.5% of patients with mALBI grade 2a improving to grade 1 by POD 180.Conclusions: Post-hepatectomy liver function at POD 180 is a key determinant of long-term survival. As this late deterioration is difficult to predict perioperatively, continuous monitoring of hepatic reserve is essential to maintain eligibility for subsequent multidisciplinary therapies.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2378-2386"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The lung-muscle metabolic axis: a proposed mechanism for post-resection systemic frailty. 肺肌肉代谢轴：切除后系统性虚弱的一种机制。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-06-04 DOI: 10.1007/s00595-026-03336-7

Ichiro Yoshino, Hisashi Saji, Hidemi Suzuki

{"title":"The lung-muscle metabolic axis: a proposed mechanism for post-resection systemic frailty.","authors":"Ichiro Yoshino, Hisashi Saji, Hidemi Suzuki","doi":"10.1007/s00595-026-03336-7","DOIUrl":"10.1007/s00595-026-03336-7","url":null,"abstract":"Long-term non-cancer mortality following lung cancer surgery remains an under-recognized challenge in clinical practice. This review proposes a novel \"pulmonary hypertensive phenotype\" hypothesis, suggesting that the permanent reduction of the pulmonary vascular bed after anatomical resection acts as the primary upstream driver of systemic vulnerability. While the ventilatory capacity may partially recover through enlargement of the airspace and compensatory remodeling, restoration of the pulmonary vascular bed is often incomplete. This deficit leads to a sustained right ventricular afterload and chronic endothelial stress. We integrated clinical and experimental evidence to suggest that this cardiopulmonary strain triggers systemic catabolic signaling, potentially mediated by factors such as GDF-15, which accelerates skeletal muscle proteolysis and attrition. This metabolic \"phase-shift\" can push patients beyond a critical threshold of vulnerability, increasing the risk of sarcopenia and non-cancer death. This could be particularly evident after extensive resections, such as pneumonectomy and lobectomy, compared with sublobar-sparing approaches. Ultimately, surgical invasiveness should be re-evaluated not only by lung volume loss but also by the preservation of the pulmonary vascular bed necessary to maintain systemic homeostasis. This framework provides a biologically plausible pathway linking the extent of resection to long-term systemic resilience and should be regarded as a conceptual integrative model that requires clinical validation.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2111-2117"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13558440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148158237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Textbook outcome after minimally invasive pulmonary resection for clinical stage I lung cancer: A retrospective cohort study. 临床I期肺癌微创肺切除术后的教科书预后：一项回顾性队列研究。

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-06-06 DOI: 10.1007/s00595-026-03350-9

Yasuaki Kubouchi, Ryota Yasuda, Yuji Nozaka, Wakako Fujiwara, Shinji Matsui, Yugo Tanaka

{"title":"Textbook outcome after minimally invasive pulmonary resection for clinical stage I lung cancer: A retrospective cohort study.","authors":"Yasuaki Kubouchi, Ryota Yasuda, Yuji Nozaka, Wakako Fujiwara, Shinji Matsui, Yugo Tanaka","doi":"10.1007/s00595-026-03350-9","DOIUrl":"10.1007/s00595-026-03350-9","url":null,"abstract":"Purpose: This study aimed to assess the textbook outcomes (TO) after minimally invasive lung cancer surgery and identify factors associated with TO failure.Methods: This retrospective study included 853 patients with clinical stage I lung cancer who underwent minimally invasive resection between 2015 and 2025 at our institution. TO was defined using predefined perioperative events. A logistic regression analysis was performed to identify the factors associated with TO failure. Cause-specific mortality was evaluated using a competing risk analysis.Results: Of the 853 patients, 647 (75.8%) achieved TO. Prolonged air leaks, reintervention, arrhythmia, prolonged hospital stay, and pneumonia were the main factors associated with TO failure. Smoking history and respiratory comorbidities were independent risk factors for TO failure. Segmentectomy was associated with a higher likelihood of achieving TO in the present study. At 5 years, no significant difference in the incidence of cancer-related death was observed between the TO and non-TO groups (5.4% vs. 4.2%, P = 0.841). However, the incidence of noncancer-related death was significantly higher in the non-TO group (13.5% vs. 10.5%, P = 0.004).Conclusion: TO was achieved in most patients who underwent minimally invasive surgery. TO failure was significantly associated with a smoking history, respiratory comorbidities, surgical procedures, and an increased incidence of noncancer-related death after minimally invasive surgery.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2255-2265"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148176777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical outcomes and prognostic factors of open-window thoracostomy for empyema: a retrospective review of 40 patients. 40例胸腔开窗术治疗脓胸的临床结果及预后因素分析

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-06-24 DOI: 10.1007/s00595-026-03338-5

Toru Kawakami, Hayato Nanami, Kiyomi Shimoda, Miyako Hiramatsu, Kazuhiro Uchimura, Yuji Shiraishi

{"title":"Clinical outcomes and prognostic factors of open-window thoracostomy for empyema: a retrospective review of 40 patients.","authors":"Toru Kawakami, Hayato Nanami, Kiyomi Shimoda, Miyako Hiramatsu, Kazuhiro Uchimura, Yuji Shiraishi","doi":"10.1007/s00595-026-03338-5","DOIUrl":"10.1007/s00595-026-03338-5","url":null,"abstract":"Purpose: Open-window thoracostomy remains a traditional yet important option for treating empyema. This study aimed to evaluate the clinical outcomes after open-window thoracostomy and identify any prognostic factors based on our institutional experience.Methods: We retrospectively reviewed the medical records of 40 consecutive patients who underwent open-window thoracostomy at our institution between January 2010 and December 2020.Results: The mean age of the patients was 68.3 years, and twenty-five were male. Thirty-five patients had empyema with a fistula and five had empyema without a fistula. The overall survival rates at one, three, and five years were 92.5 percent, 72.9 percent, and 55.9 percent, respectively. A univariate Cox regression analysis followed by a multivariate Cox regression analysis identified three independent prognostic factors for overall survival: preoperative contralateral aspiration pneumonia, prognostic nutritional index < 37.4 (area under the curve 0.742 by receiver operating characteristic analyses), and an elevated white blood cell count.Conclusions: The preoperative nutritional status, systemic inflammation, and the presence of contralateral aspiration pneumonia were strongly associated with survival after open-window thoracostomy. This study highlights the importance of these factors in the management of empyema.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2420-2429"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for one-year mortality and the subsequent prognosis in older patients undergoing curative surgery for colorectal cancer: a retrospective multicenter study. 高龄结直肠癌根治性手术患者一年死亡率及预后的危险因素：一项回顾性多中心研究

IF 2.3 4区医学

Surgery Today Pub Date : 2026-10-01 Epub Date: 2026-07-01 DOI: 10.1007/s00595-026-03384-z

Shintaro Hashimoto, Tetsuro Tominaga, Keisuke Noda, Toshio Shiraishi, Mariko Yamashita, Hiroki Katayama, Shoko Tei, Taiji Hida, Hiroshi Maruta, Yuma Takamura, Rika Ono, Makoto Hisanaga, Mitsutoshi Ishii, Masaaki Moriyama, Hidetoshi Fukuoka, Kazuo To, Kaido Oishi, Hiroaki Takeshita, Terumitsu Sawai, Takashi Nonaka, Keitaro Matsumoto

{"title":"Risk factors for one-year mortality and the subsequent prognosis in older patients undergoing curative surgery for colorectal cancer: a retrospective multicenter study.","authors":"Shintaro Hashimoto, Tetsuro Tominaga, Keisuke Noda, Toshio Shiraishi, Mariko Yamashita, Hiroki Katayama, Shoko Tei, Taiji Hida, Hiroshi Maruta, Yuma Takamura, Rika Ono, Makoto Hisanaga, Mitsutoshi Ishii, Masaaki Moriyama, Hidetoshi Fukuoka, Kazuo To, Kaido Oishi, Hiroaki Takeshita, Terumitsu Sawai, Takashi Nonaka, Keitaro Matsumoto","doi":"10.1007/s00595-026-03384-z","DOIUrl":"10.1007/s00595-026-03384-z","url":null,"abstract":"Purpose: Postoperative complications may affect the long-term outcomes after colorectal cancer (CRC) surgery. This multicenter study compared prognostic factors for overall survival (OS) in younger (≤ 74 years) and older (≥ 75 years) patients after curative resection for CRC, focusing on the 1-year and post-1-year outcomes.Methods: We analyzed data from 1582 patients who underwent curative surgery for CRC at six hospitals between April 2016 and December 2019. Kaplan-Meier and Cox models were used to identify the risk factors for complications and survival.Results: Older patients had a significantly worse overall survival (OS) and survival beyond the 1-year landmark. Postoperative complications were associated with increased 1-year mortality in both age groups. In younger patients, survival beyond 1 year was associated with a positive N status and a low BMI. In contrast, in older patients, postoperative complications remained associated with survival beyond the 1-year landmark, along with a male sex, positive N status, and poor ASA-PS.Conclusions: The prolonged impact of complications on survival in older patients with CRC underscores the need for age-specific surgical strategies and proactive complication management.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"2439-2446"},"PeriodicalIF":2.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0