{"title":"The Key Ripper: a specialized fixed suture-cutting device to facilitate drain removal.","authors":"Shogo Nagamatsu, Ayano Sasaki, Yumiwo Fujioka, Yoshiaki Shibata, Ken Nomimura, Yuki Aoki, Isao Koshima","doi":"10.1007/s00595-024-02897-9","DOIUrl":"10.1007/s00595-024-02897-9","url":null,"abstract":"<p><p>The removal of post-surgical drains requires suture cutting. We developed a novel and specialized device that can safely remove the threads fixing the drains, making drain removal safer and easier than the current removal approach using scissors or a scalpel.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"442-444"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of vacuum-assisted wound closure and mesh-mediated fascial traction in open abdomen management.","authors":"Kenta Shigeta, Shiei Kim, Ryuta Nakae, Yutaka Igarashi, Taigo Sakamoto, Tomoko Ogasawara, Tomohiko Masuno, Masatoku Arai, Shoji Yokobori","doi":"10.1007/s00595-024-02899-7","DOIUrl":"10.1007/s00595-024-02899-7","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the effectiveness of vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) in patients undergoing open abdomen management (OAM).</p><p><strong>Methods: </strong>Data from cases with OAM for at least five days who were admitted to our institution between January 2011 and December 2020 were included. We compared the patient's age, sex, medical history, indication for initial surgery, APACHE II scores, indication for OAM, operative time, intraoperative blood loss, intraoperative transfusion, success of primary fascial closure (rectus fascial closure and bilateral anterior rectus abdominis sheath turnover flap method), success of planned ventral hernia, duration of OAM, and in-hospital mortality between patients undergoing VAWCM (VAWCM cases, n = 27) and vacuum-assisted wound closure (VAWC) alone (VAWC cases, n = 25).</p><p><strong>Results: </strong>VAWCM cases had a significantly higher success rate of primary fascial closure (70% vs. 36%, p = 0.030) and lower in-hospital mortality (26% vs. 72%, p = 0.002) than VAWC cases. A multivariate logistic regression analysis showed that VAWCM was an independent factor influencing in-hospital mortality (odds ratio, 0.14; 95% confidence interval: 0.04-0.53; p = 0.004).</p><p><strong>Conclusion: </strong>VAWCM is associated with an increased rate of successful primary fascial closure and may reduce in-hospital mortality.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"335-342"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of serum lactate dehydrogenase with prognosis and tumor metabolism in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab therapy.","authors":"Katsuya Toshida, Shinji Itoh, Takeo Toshima, Shohei Yoshiya, Yuki Bekki, Takuma Izumi, Norifumi Iseda, Yuki Nakayama, Takuma Ishikawa, Tomoharu Yoshizumi","doi":"10.1007/s00595-024-02914-x","DOIUrl":"10.1007/s00595-024-02914-x","url":null,"abstract":"<p><strong>Purpose: </strong>Treatment outcomes are predicted by analyzing peripheral blood markers such as serum lactate dehydrogenase (LDH). We conducted this study to investigate whether serum LDH levels can predict the prognosis of patients treated with atezolizumab plus bevacizumab (ATZ/BEV) therapy for hepatocellular carcinoma (HCC) and whether LDH levels correlate with metabolic changes.</p><p><strong>Methods: </strong>We enrolled 66 HCC patients treated with ATZ/BEV. Based on the change in serum LDH levels before and after treatment, the patients were divided into two groups, and the prognosis of each group was examined. Moreover, the association of LDH levels with tumor metabolism was analyzed by fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT).</p><p><strong>Results: </strong>There were 32 patients categorized as the LDH-decrease group. Kaplan-Meier survival analysis indicated worse progression-free survival (PFS) in the LDH-increase group than in the LDH-decrease group (p = 0.0029). Multivariate analysis showed that an increase in the LDH level was an independent risk factor for worse PFS (p = 0.0045). The baseline LDH level correlated significantly with a high maximum standardized uptake value of <sup>18</sup>F-FDG, according to the PET/CT findings. Transcriptomic analyses of specimens resected after ATZ/BEV therapy showed downregulated mitochondria-related pathways.</p><p><strong>Conclusion: </strong>Serum LDH levels are a potential prognostic marker and an indicator of tumor metabolism.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"370-379"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of changes in appendicular skeletal muscle mass with weight loss and visceral fat reduction after laparoscopic sleeve gastrectomy.","authors":"Kohei Uno, Kazuhide Sato, Atsushi Watanabe, Tomohiro Kudo, Naoko Fukushima, Keita Takahashi, Takahiro Masuda, Takanori Kurogochi, Masami Yuda, Fumiaki Yano, Ken Eto","doi":"10.1007/s00595-024-02925-8","DOIUrl":"10.1007/s00595-024-02925-8","url":null,"abstract":"<p><strong>Purpose: </strong>Laparoscopic sleeve gastrectomy (LSG) drastically affects body composition. However, studies focusing on the association between the changes in the pre-and postoperative muscle mass and postoperative results are limited. We evaluated the association between changes in the muscle mass and weight loss and fat reduction.</p><p><strong>Methods: </strong>This retrospective study included 29 consecutive patients who underwent both LSG and a bioelectrical impedance analysis (BIA) consecutively. We investigated changes in the body composition on the BIA and visceral fat area (VFA) on computed tomography and correlational changes in muscle mass with weight loss and fat reduction.</p><p><strong>Results: </strong>The total weight loss (%TWL) 12 months after surgery was 30.9%. The VFAs pre- and postoperatively were 224 and 71.0 cm<sup>2</sup>, respectively. The fat mass (FM), percentage of FM, appendicular skeletal muscle mass (ASM), and skeletal muscle mass index (SMI) decreased from pre- to postoperatively (54.8 vs. 32.2 kg; 49.0 vs. 41.2%, 26.7 vs. 23.9 kg, 9.24 vs. 8.27, respectively), whereas the percentage of ASM (%ASM) increased (22.1 vs. 28.0%). The rate of change in %ASM positively correlated with weight loss and fat reduction (%TWL, rs = 0.65; %VFA loss, rs = 0.62).</p><p><strong>Conclusion: </strong>The rate of change in %ASM was positively correlated with weight loss and fat reduction.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"434-441"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prophylactic effect of tissue flap in the prevention of bronchopleural fistula after surgery for lung cancer.","authors":"Tomohiro Habu, Hiromasa Yamamoto, Kentaro Nakata, Kohei Hashimoto, Shin Tanaka, Kazuhiko Shien, Ken Suzawa, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Shinichi Toyooka","doi":"10.1007/s00595-024-02927-6","DOIUrl":"10.1007/s00595-024-02927-6","url":null,"abstract":"<p><strong>Purpose: </strong>Bronchopleural fistula (BPF) is a serious complication of lung resection. To avoid BPF, the bronchial stump/anastomotic site is often covered with a flap of surrounding tissue. One risk factor for BPF is radical lung resection after induction chemoradiotherapy for lung cancer. We retrospectively reviewed our database to elucidate the characteristics of tissue flaps that prevent BPF.</p><p><strong>Methods: </strong>This retrospective study included 152 patients treated between 1999 and 2019. We examined the clinicopathological characteristics, including the type and thickness of the tissue flap used to cover the bronchial stump/anastomotic site, and postoperative complications, including BPF.</p><p><strong>Results: </strong>BPF occurred in 5 patients (3.3%). All 5 patients had complications that could have affected delayed wound healing, such as pneumonia. The covering tissue flap thickness was significantly greater in patients without BPF than in those who developed BPF (p = 0.0290). Additionally, the tissue flap thickness was significantly greater than in those with BPF (p = 0.0077), even in high-risk patients who developed pneumonia or radiation pneumonitis on the operative side within 6 months postoperatively.</p><p><strong>Conclusion: </strong>Perioperative management is crucial to avoid complications affecting the healing of the bronchial stump/anastomotic site, and the covering tissue flap thickness may be an important factor in avoiding or minimizing BPF.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"405-413"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery TodayPub Date : 2025-02-28DOI: 10.1007/s00595-025-03016-y
Takaaki Oba, Kazuma Maeno, Ryoko Iji, Nami Kiyosawa, Yonghan Park, Hiroki Morikawa, Masatsugu Amitani, Tadafumi Shimizu, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Hisanori Matoba, Fumiyoshi Takayama, Ken-Ichi Ito
{"title":"Utility of contrast-enhanced magnetic resonance imaging for planning of surgical procedure in Paget's disease of the breast.","authors":"Takaaki Oba, Kazuma Maeno, Ryoko Iji, Nami Kiyosawa, Yonghan Park, Hiroki Morikawa, Masatsugu Amitani, Tadafumi Shimizu, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Hisanori Matoba, Fumiyoshi Takayama, Ken-Ichi Ito","doi":"10.1007/s00595-025-03016-y","DOIUrl":"https://doi.org/10.1007/s00595-025-03016-y","url":null,"abstract":"<p><strong>Purpose: </strong>Contrast-enhanced magnetic resonance imaging (CE-MRI) is an essential imaging modality for planning breast cancer surgical procedures. However, CE-MRI findings in Paget's disease of the breast (PD) have not been studied extensively. This study aimed to elucidate the CE-MRI findings of PD and assess their role in surgical treatment planning.</p><p><strong>Methods: </strong>Twelve patients with PD who underwent surgery between 2011 and 2023 were retrospectively analyzed.</p><p><strong>Results: </strong>The average patient age was 73.8 ± 14.3 years. CE-MRI detected enhanced areas in the nipple-areola complex (NAC) and/or surrounding skin in all patients. Additionally, 6 patients showed enhanced areas within the breast, suggesting ductal spread into the breast. Of these, 1 patient underwent breast-conserving surgery (BCS), and 5 opted for mastectomy. Pathology confirmed the extent of ductal spread of PD, as indicated by CE-MRI. Among the 6 patients who did not have an enhanced area in the breast, 3 underwent BCS or central lumpectomy including NAC, and 3 chose mastectomy based on the patient's preference, and no malignant foci were observed in the breast.</p><p><strong>Conclusion: </strong>CE-MRI effectively evaluated the ductal spread of PD in the breast, demonstrating its utility in guiding the selection of surgical procedures.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment strategy and clinical outcomes of thoracoscopic endoscopic cooperative surgery for submucosal tumors in the esophagus.","authors":"Yasunori Otowa, Fumiaki Kawara, Gosuke Takiguchi, Kodai Yamanaka, Tadahiro Goto, Chiharu Nishioka, Daisuke Kuroda, Yonson Ku","doi":"10.1007/s00595-025-03003-3","DOIUrl":"https://doi.org/10.1007/s00595-025-03003-3","url":null,"abstract":"<p><strong>Purpose: </strong>Recently, submucosal tumors (SMTs) of the esophagus have been treated with peroral endoscopic tumor resection (POET) and a new procedure called thoracoscopic endoscopic cooperative surgery (TECS). This study aimed to validate the treatment strategy for SMTs and determine whether or not TECS is a viable option when POET is not feasible.</p><p><strong>Methods: </strong>POET and TECS were performed in 12 patients between February 2020 and January 2024. The clinical characteristics and perioperative outcomes were retrospectively evaluated.</p><p><strong>Results: </strong>Six patients were included in each group, with most of the tumors located in the middle thoracic esophagus (75%). The general anesthesia duration was significantly longer in the TECS group than in the POET group (P < 0.001), but no significant differences in endoscopic procedure time, tumor mass index, oral intake date, or length of hospital stay were observed between the two groups. En bloc and R0 resections were performed in all patients. One patient in the TECS group experienced a Clavien-Dindo grade 3a adverse event, and no tumor recurrence occurred during the median follow-up period of 33 (range, 6-53) months.</p><p><strong>Conclusion: </strong>TECS is a safe and feasible option for SMTs when POET is difficult to perform.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safety and efficacy of neoadjuvant cisplatin + S-1 combined with radiation therapy for locally advanced non-small cell lung cancer.","authors":"Takashi Karashima, Shinkichi Takamori, Miyuki Abe, Yohei Takumi, Atsushi Osoegawa, Kenji Sugio","doi":"10.1007/s00595-025-03019-9","DOIUrl":"https://doi.org/10.1007/s00595-025-03019-9","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the safety and efficacy of neoadjuvant chemoradiotherapy with cisplatin plus S-1 for advanced non-small cell lung cancer (NSCLC), with a focus on real-world outcomes.</p><p><strong>Methods: </strong>This retrospective study analyzed 32 patients with stage II-III NSCLC eligible for resection, who received preoperative induction therapy between January 2012 and December 2022. Specifically, 20 patients received cisplatin, S-1, and radiation therapy.</p><p><strong>Results: </strong>Among the 32 patients who received induction therapy, the objective response rate (ORR) was 56.2%, and surgical resection was feasible in 29 patients (90.6%). The 5 year recurrence-free survival (RFS) rate was 76.4%, and the 3- and 5 year overall survival (OS) rates were 86.2% and 82.3%, respectively. In the cisplatin + S-1 + radiation therapy group (n = 20), the ORR was 65.0%, and surgical resection was feasible in 17 patients (85.0%). The 3-year RFS and OS rates were 78.3% and 83.8%, respectively. Ef. 3 (complete pathological response) was observed in 3 patients (10.3%). No recurrences occurred in the non-adenocarcinoma subgroup (n = 6), indicating better outcomes relative to the adenocarcinoma group (5-year RFS, 100% vs. 61.4%; p = 0.07).</p><p><strong>Conclusions: </strong>Induction therapy, particularly with cisplatin + S-1 + radiation was associated with promising RFS and OS in locally advanced NSCLC, with favorable tolerability and effectiveness.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An increase in micro-vessels beneath the pleural surface on computed tomography as a preoperative predictor of pleural adhesions: a prospective study.","authors":"Tomoyuki Kawamura, Naohiro Kobayashi, Takahiro Yanagihara, Yukinobu Goto, Hideo Ichimura, Yukio Sato","doi":"10.1007/s00595-025-03022-0","DOIUrl":"https://doi.org/10.1007/s00595-025-03022-0","url":null,"abstract":"<p><strong>Purpose: </strong>Pleural adhesions, which may be present in varying degrees and involve blood vessels, often complicate thoracic surgery. The blood flow within pleural adhesions can be identified on computed tomography (CT) as micro-vessels beneath the pleural surface (MVBP). We conducted a prospective study to assess if MVBP can be detected on preoperative CT to predict intraoperative pleural adhesions.</p><p><strong>Methods: </strong>This prospective study investigated the preoperative CT images of patients scheduled to undergo surgery for lung tumors. MVBP was defined as positive when lung vessels were identified below the pleura on CT. MVBP was evaluated for each lung segment, and intraoperative findings of pleural adhesions on the segments were then recorded.</p><p><strong>Results: </strong>This study included 173 patients, with 1532 segments evaluated. Pleural adhesions were found in 51 patients and confirmed in 92 segments. The number of segments evaluated preoperatively as MVBP-positive was 134 (9%), of which 36 (26.9%) had pleural adhesions. Multivariable analysis identified that MVBP was an independent significant predictor (odds ratio = 2.29, 95% confidence interval 1.09-4.80, P = 0.028) of pleural adhesions on a per-patient basis.</p><p><strong>Conclusions: </strong>MVBP is a valuable predictor of pleural adhesions. The method is useful in clinical practice because it does not require additional examinations and is easy to assess.</p>","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}