Surgery Today最新文献_第6页

Impact of the novel coronavirus infection on pediatric surgery: an analysis of data from the National Clinical Database. 新型冠状病毒感染对小儿外科手术的影响：国家临床数据库数据分析。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-02-13 DOI: 10.1007/s00595-024-02792-3

Kazuya Ise, Hisateru Tachimori, Jun Fujishiro, Hirofumi Tomita, Kan Suzuki, Hiroyuki Yamamoto, Hiroaki Miyata, Yasushi Fuchimoto

{"title":"Impact of the novel coronavirus infection on pediatric surgery: an analysis of data from the National Clinical Database.","authors":"Kazuya Ise, Hisateru Tachimori, Jun Fujishiro, Hirofumi Tomita, Kan Suzuki, Hiroyuki Yamamoto, Hiroaki Miyata, Yasushi Fuchimoto","doi":"10.1007/s00595-024-02792-3","DOIUrl":"10.1007/s00595-024-02792-3","url":null,"abstract":"Purpose: The coronavirus disease 2019 (COVID-19) pandemic limited the delivery of medical resources. Although surgeries are triaged according to disease severity and urgency, a delay in diagnosis and surgery can be detrimental. We conducted this study to analyze data on the impact of the COVID-19 pandemic on pediatric surgery for different diseases or disorders.Methods: We compiled and compared data on pediatric surgical cases from 2018 to 2020, using the National Clinical Database. The number of diseases, severity, complication rates, mortality rates by disease/disorder, and the COVID-19 pandemic areas were analyzed.Results: The total number of cases of pediatric surgery in 2018, 2019, and 2020 was 50,026, 49,794, and 45,621, respectively, reflecting an 8.8% decrease in 2020 from 2018 and an 8.4% decrease in 2020 from 2019. A decrease was observed when the number of patients with COVID-19 was high and was greater in areas with a low infection rate. There was a marked decrease in the number of inguinal hernia cases. The number of emergency room visits and emergency surgeries decreased, but their relative proportions increased.Conclusions: The COVID-19 pandemic decreased the number of pediatric surgeries, reflecting the limitations of scheduled surgeries and infection control measures.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11266367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How should cardiac xenotransplantation be initiated in Japan? 日本应如何启动心脏异种移植？

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-05-11 DOI: 10.1007/s00595-024-02861-7

Shunsuke Saito, Shuji Miyagawa, Takuji Kawamura, Daisuke Yoshioka, Masashi Kawamura, Ai Kawamura, Yusuke Misumi, Takura Taguchi, Takashi Yamauchi, Shigeru Miyagawa

{"title":"How should cardiac xenotransplantation be initiated in Japan?","authors":"Shunsuke Saito, Shuji Miyagawa, Takuji Kawamura, Daisuke Yoshioka, Masashi Kawamura, Ai Kawamura, Yusuke Misumi, Takura Taguchi, Takashi Yamauchi, Shigeru Miyagawa","doi":"10.1007/s00595-024-02861-7","DOIUrl":"10.1007/s00595-024-02861-7","url":null,"abstract":"The world's first clinical cardiac xenotransplantation, using a genetically engineered pig heart with 10 gene modifications, prolonged the life of a 57-year-old man with no other life-saving options, by 60 days. It is foreseeable that xenotransplantation will be introduced in clinical practice in the United States. However, little clinical or regulatory progress has been made in the field of xenotransplantation in Japan in recent years. Japan seems to be heading toward a \"device lag\", and the over-importation of medical devices and technology in the medical field is becoming problematic. In this review, we discuss the concept of pig-heart xenotransplantation, including the pathobiological aspects related to immune rejection, coagulation dysregulation, and detrimental heart overgrowth, as well as genetic modification strategies in pigs to prevent or minimize these problems. Moreover, we summarize the necessity for and current status of xenotransplantation worldwide, and future prospects in Japan, with the aim of initiating xenotransplantation in Japan using genetically modified pigs without a global delay. It is imperative that this study prompts the initiation of preclinical xenotransplantation research using non-human primates and leads to clinical studies.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11266268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140908812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of atrial fibrillation after esophageal cancer surgery with L-carnitine use: a preliminary single-group interventional study. 使用左旋肉碱的食管癌术后心房颤动发生率：一项初步的单组干预研究。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-02-23 DOI: 10.1007/s00595-024-02802-4

Yasushige Shingu, Isao Yokota, Toshiaki Shichinohe, Soichi Murakami, Yuma Ebihara, Yo Kurashima, Satoshi Hirano, Satoru Wakasa

{"title":"Incidence of atrial fibrillation after esophageal cancer surgery with L-carnitine use: a preliminary single-group interventional study.","authors":"Yasushige Shingu, Isao Yokota, Toshiaki Shichinohe, Soichi Murakami, Yuma Ebihara, Yo Kurashima, Satoshi Hirano, Satoru Wakasa","doi":"10.1007/s00595-024-02802-4","DOIUrl":"10.1007/s00595-024-02802-4","url":null,"abstract":"Purpose: We aimed to investigate the POAF rate and blood FABP4 levels after perioperative L-carnitine administration in patients with esophageal cancer.Methods: L-carnitine (3 g in three divided doses) was administered to 15 patients 2 days before and 3 days after surgery. POAF during the study period and blood FABP4 levels (ELISA) before and after L-carnitine administration were evaluated. Accurate 95% confidence intervals (CI) for POAF incidence and changes in blood FABP4 levels were calculated. The preoperative predicted POAF rate was calculated using an application for esophageal cancer. The correlation between FABP4 levels and the predicted POAF rate was analyzed using Pearson's coefficient (r).Results: Thirteen patients completed this study. The predicted POAF rate was 24% (17%, 34%) (median; interquartile range). The actual incidence of POAF was 7.7% (95% CI: 0.2-36%). Blood FABP4 levels changed from 10.3 to 7.0 ng/mL; the average change was - 3.3 (95% CI: - 6.6 to - 0.1). A positive correlation was found between preoperative FABP4 levels and the predicted POAF rates (r = 0.564).Conclusions: The POAF rate after esophageal surgery was 7.7% for L-carnitine. L-carnitine may reduce blood FABP4 levels. This preliminary study will contribute to the planning of sample sizes in future randomized trials.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139932891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salvage extended surgery after immune-checkpoint inhibitor treatment for advanced non-small cell lung cancer. 免疫检查点抑制剂治疗晚期非小细胞肺癌后的挽救性延长手术。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-03-22 DOI: 10.1007/s00595-024-02812-2

Eisuke Goto, Aritoshi Hattori, Mariko Fukui, Takeshi Matsunaga, Kazuya Takamochi, Kenji Suzuki

{"title":"Salvage extended surgery after immune-checkpoint inhibitor treatment for advanced non-small cell lung cancer.","authors":"Eisuke Goto, Aritoshi Hattori, Mariko Fukui, Takeshi Matsunaga, Kazuya Takamochi, Kenji Suzuki","doi":"10.1007/s00595-024-02812-2","DOIUrl":"10.1007/s00595-024-02812-2","url":null,"abstract":"Purpose: We evaluated the surgical outcomes of salvage extended surgery after definitive medical treatment with an immune-checkpoint inhibitor (ICI) for locally advanced or unresectable non-small-cell lung cancer (NSCLC).Methods: The subjects of this single-center retrospective analysis were 14 patients who underwent salvage surgery after ICI treatment between May, 2017 and April, 2023 at our institute. We reviewed the comprehensive surgical outcomes, including operative procedures, intraoperative findings, and postoperative morbidities. Overall survival (OS) was calculated using a Kaplan-Meier estimation.Results: The initial clinical stage before medical treatment (c-stage) was stage III in eight patients, stage IV in five patients, and one patient had postoperative lung cancer recurrence. The indications for surgery were as follows: local control for relapse or residual tumor in ten patients and discontinuation of systemic therapy because of treatment-related complications in four patients. The surgical modes were segmentectomy (n = 1), lobectomy (n = 4), bilobectomy (n = 3), pneumonectomy (n = 6), and bronchoplasty (n = 7). Grade 3 or higher postoperative morbidities were observed in six patients, including only one case of 90-day mortality.Conclusions: Our series demonstrated that the surgical outcome of salvage extended surgery after ICI therapy may be positive with careful selection of the procedure and indication.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140190106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ChatGPT in surgery: a revolutionary innovation? 手术中的 ChatGPT：革命性创新？

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-02-29 DOI: 10.1007/s00595-024-02800-6

Mustafa Bektaş, Jaime Ken Pereira, Freek Daams, Donald L van der Peet

引用次数: 0

Salivary metabolites as potential predictive biomarkers for lung surgery complications: a retrospective cross-sectional study. 作为肺部手术并发症潜在预测生物标志物的唾液代谢物：一项回顾性横断面研究。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-02-15 DOI: 10.1007/s00595-024-02794-1

Satoshi Takamori, Shigeo Ishikawa, Kaito Sato, Hikaru Watanabe, Jun Suzuki, Hiroyuki Oizumi, Satoshi Shiono, Tetsuro Uchida, Naoki Okuyama, Kaoru Edamatsu, Mitsuyoshi Iino, Masahiro Sugimoto

{"title":"Salivary metabolites as potential predictive biomarkers for lung surgery complications: a retrospective cross-sectional study.","authors":"Satoshi Takamori, Shigeo Ishikawa, Kaito Sato, Hikaru Watanabe, Jun Suzuki, Hiroyuki Oizumi, Satoshi Shiono, Tetsuro Uchida, Naoki Okuyama, Kaoru Edamatsu, Mitsuyoshi Iino, Masahiro Sugimoto","doi":"10.1007/s00595-024-02794-1","DOIUrl":"10.1007/s00595-024-02794-1","url":null,"abstract":"Purpose: Saliva is often used as a tool for identifying systemic diseases because of the noninvasive nature of its collection. Moreover, salivary metabolites can be potential predictive factors for postoperative survival. We conducted the present study to establish whether salivary metabolites can function as predictive biomarkers for lung surgery complications.Methods: Unstimulated salivary samples were collected from 412 patients before lung surgery. Salivary metabolites were analyzed comprehensively by capillary electrophoresis mass spectrometry. Clinical data with the discriminatory ability of biomarkers were assessed to predict lung surgery complications using multivariate logistic regression analysis. The primary endpoint was the risk factors for postoperative complications of Clavien-Dindo grade ≥ III.Results: Postoperative complications of Clavien-Dindo grade ≥ III developed in 36 patients (8.7%). There was no postoperative 30-day mortality. Male sex (odds ratio [OR], 3.852; 95% confidence interval CI 1.455-10.199; p = 0.007) and salivary gamma-butyrobetaine (OR, 0.809; 95% CI 0.694-0.943; p = 0.007) were identified as significant risk factors for postoperative complications of Clavien-Dindo grade ≥ III.Conclusion: Salivary metabolites are potential noninvasive biomarkers for predicting postoperative complications of lung surgery.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of low anterior resection syndrome and its association with the quality of life in patients with lower rectal tumors. 低位前切除综合征的发病率及其与下直肠肿瘤患者生活质量的关系。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-03-12 DOI: 10.1007/s00595-024-02796-z

Yuko Homma, Toshiki Mimura, Koji Koinuma, Hisanaga Horie, Naohiro Sata

{"title":"Incidence of low anterior resection syndrome and its association with the quality of life in patients with lower rectal tumors.","authors":"Yuko Homma, Toshiki Mimura, Koji Koinuma, Hisanaga Horie, Naohiro Sata","doi":"10.1007/s00595-024-02796-z","DOIUrl":"10.1007/s00595-024-02796-z","url":null,"abstract":"Purpose: Low anterior resection syndrome (LARS) causes devastating symptoms and impairs the quality of life (QOL). This study investigated the incidence and risk factors of LARS and their association with the QOL in patients with lower rectal tumors.Methods: Patients who underwent anus-preserving surgery for lower rectal tumors between 2014 and 2019 and who had anal defecation between 2020 and 2021 were surveyed. The LARS score measured severity, and the QOL was evaluated using the Japanese version of the Fecal Incontinence Quality-of-Life Scale (JFIQL). The primary endpoint was the incidence of Major LARS, and the secondary endpoints were risk factors and association with the JFIQL.Results: Of 107 eligible patients, 82 (76.6%) completed the LARS survey. The incidence of Major LARS was 48%. Independent risk factors included neoadjuvant chemoradiotherapy (CRT) and a short interval (< 24 months after surgery; odds ratio, 4.6; 95% confidence interval: 1.1-19, both). The LARS score was moderately correlated with the JFIQL generic score (correlation coefficient: - 0.54). The JFIQL scores were significantly worse in the Minor and Major LARS groups than in the No LARS group.Conclusions: Major LARS was found in 48% of lower rectal tumors, and independent risk factors include neoadjuvant CRT and a short interval. The QOL was significantly impaired in patients with both Minor and Major LARS.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel concept of "sequential particle radiotherapy" with atezolizumab plus bevacizumab for hepatocellular carcinoma with portal vein tumor thrombus. 用阿特珠单抗加贝伐单抗的 "序贯粒子放疗 "治疗伴有门静脉瘤栓的肝细胞癌的新概念。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-03-04 DOI: 10.1007/s00595-024-02805-1

Shohei Komatsu, Kazuki Terashima, Nobuaki Ishihara, Yoshiro Matsuo, Masahiro Kido, Hiroaki Yanagimoto, Hirochika Toyama, Sunao Tokumaru, Tomoaki Okimoto, Takumi Fukumoto

{"title":"Novel concept of \"sequential particle radiotherapy\" with atezolizumab plus bevacizumab for hepatocellular carcinoma with portal vein tumor thrombus.","authors":"Shohei Komatsu, Kazuki Terashima, Nobuaki Ishihara, Yoshiro Matsuo, Masahiro Kido, Hiroaki Yanagimoto, Hirochika Toyama, Sunao Tokumaru, Tomoaki Okimoto, Takumi Fukumoto","doi":"10.1007/s00595-024-02805-1","DOIUrl":"10.1007/s00595-024-02805-1","url":null,"abstract":"Owing to the high objective response rate of atezolizumab plus bevacizumab (Atez/Bev) for hepatocellular carcinoma (HCC), the concept of sequential conversion to local treatment has recently become mainstream. The conversion concept is mainly applied to Barcelona Clinic for Liver Cancer (BCLC) stage B cases, and radiotherapy is rarely considered as a conversion local treatment. We herein report three patients who were treated with the novel concept of \"sequential particle radiotherapy,\" consisting of Atez/Bev therapy followed by particle radiotherapy (PRT) for HCC with advanced portal vein tumor thrombus (Vp3/4 PVTT). All patients achieved partial response radiologically and were switched to PRT. All patients were recurrence free at 1 year after the introduction of Atez/Bev therapy without any additional treatment. This upcoming combination strategy includes the advocacy of sequential concepts for BCLC stage C cases and the introduction of PRT as a local treatment after Atez/Bev.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic significance of the preoperative C-reactive protein-albumin-lymphocyte (CALLY) index on outcomes after gastrectomy for gastric cancer. 术前C反应蛋白-白蛋白-淋巴细胞（CALLY）指数对胃癌胃切除术后预后的意义。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 Epub Date: 2024-03-15 DOI: 10.1007/s00595-024-02813-1

Naoko Fukushima, Takahiro Masuda, Kazuto Tsuboi, Keita Takahashi, Masami Yuda, Muneharu Fujisaki, Toru Ikegami, Fumiaki Yano, Ken Eto

{"title":"Prognostic significance of the preoperative C-reactive protein-albumin-lymphocyte (CALLY) index on outcomes after gastrectomy for gastric cancer.","authors":"Naoko Fukushima, Takahiro Masuda, Kazuto Tsuboi, Keita Takahashi, Masami Yuda, Muneharu Fujisaki, Toru Ikegami, Fumiaki Yano, Ken Eto","doi":"10.1007/s00595-024-02813-1","DOIUrl":"10.1007/s00595-024-02813-1","url":null,"abstract":"Purpose: Systemic inflammatory response markers are reported to be prognostic for patients with cancer. The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index has been established as an immuno-nutritional scoring system. The aim of this study was to clarify the impact of the preoperative CALLY index on the outcome of patients undergoing gastrectomy for gastric cancer.Methods: We analyzed the data of 826 patients who underwent gastrectomy for stage I, II, or III gastric cancer between 2010 and 2017. The CALLY index was defined as (albumin × lymphocyte)/(CRP × 104).Results: The cut-off of the CALLY index was 2. The 147 patients with a preoperative CALLY index < 2 had significantly worse overall survival (OS) and relapse-free survival (RFS) than those with a CALLY index ≥ 2 (P < 0.01, P < 0.01, respectively). Multivariate analysis identified that a CALLY index < 2 (P = 0.02), intraoperative blood loss (P < 0.01), and stage II or III disease (P < 0.01) were independent and significant predictors of worse RFS. A CALLY index < 2 (P = 0.01), intraoperative blood loss (P < 0.01), postoperative complications (P = 0.02), and stage II or III disease (P < 0.01) were independent and significant predictors of worse OS.Conclusion: The preoperative CALLY index was independently associated with a poor prognosis for patients after gastrectomy for gastric cancer.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment outcomes in non-occlusive mesenteric ischemia and post-treatment return to social activities. 非闭塞性肠系膜缺血的治疗效果和治疗后恢复社会活动的情况。

IF 1.7 4区医学

Surgery Today Pub Date : 2024-08-01 DOI: 10.1007/s00595-024-02909-8

Gaku Ohira, Koichi Hayano, Toru Tochigi, Tetsuro Maruyama, Takeshi Toyozumi, Yoshihiro Kurata, Michihiro Maruyama, Satoko Arai, Taka-Aki Nakada, Hisahiro Matsubara

{"title":"Treatment outcomes in non-occlusive mesenteric ischemia and post-treatment return to social activities.","authors":"Gaku Ohira, Koichi Hayano, Toru Tochigi, Tetsuro Maruyama, Takeshi Toyozumi, Yoshihiro Kurata, Michihiro Maruyama, Satoko Arai, Taka-Aki Nakada, Hisahiro Matsubara","doi":"10.1007/s00595-024-02909-8","DOIUrl":"https://doi.org/10.1007/s00595-024-02909-8","url":null,"abstract":"Purpose: To investigate the treatment outcomes of patients with non-occlusive mesenteric ischemia (NOMI) at our institution, we focused on their post-treatment return to social activities.Methods: This study included patients with suspected NOMI who were referred to our department between 2011 and 2023. In-hospital mortality was also investigated as a prognostic factor. The Glasgow-Pittsburgh Outcome Categories (GPOC) score was used to evaluate the return to social activities. The relationship between in-hospital mortality and GPOC scores and patient background and treatment factors was examined.Results: Eighty-two patients were included in the study. Among them, 54 (65.9%) died during hospitalization. Only 9 patients (11%) returned to their social activities. In the multivariate analysis, non-surgical management was found to be the only independent factor for in-hospital mortality. Positive portal venous gas on computed tomography, no open abdomen, no pre-onset catecholamine administration, platelet count < 100,000/µL, lactate level < 5 mmol/L, APTT < 46 s, and Sequential Organ Failure Assessment score < 11 were factors significantly associated with an increased likelihood of return to social activities.Conclusion: This is the first study to assess the post-treatment return to social activities among patients with NOMI. Our findings highlight the concerning reality that survivors may face prolonged dependence on medical care.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0