The association of intraoperative hyperglycemia and postoperative infectious complications after lung transplantation: a single-center retrospective study.

IF 1.6 4区 医学 Q2 SURGERY
Hideki Nagata, Takashi Kanou, Kenji Kimura, Eriko Fukui, Toru Kimura, Naoko Ose, Yasushi Shintani
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引用次数: 0

Abstract

Purpose: Postoperative infections remain a significant problem in lung transplantation. We explored factors associated with postoperative infection after lung transplantation, including intraoperative hyperglycemia.

Methods: Forty-six lung transplant patients were included in the study. The background of these patients and the relationship between each factor and postoperative infectious complications were retrospectively investigated. In the present study, intraoperative hyperglycemia was defined as a mean intraoperative blood glucose level of ≥ 180 mg/dL.

Results: Nineteen patients were classified into the intraoperative hyperglycemia group. Eighteen patients had postoperative infections, and the intraoperative hyperglycemia group had a higher rate of postoperative infections than the non-hyperglycemia group. A multivariate analysis showed that intraoperative hyperglycemia was independently associated with post-transplantation infection (p < 0.01). The 5-year overall survival rates of the intraoperative hyperglycemia and non-hyperglycemia groups were 59.2% and 75.0%, respectively, whereas those of the post-transplant infection and non-infected groups were 47.7% and 80.0%, respectively, with a trend toward a worse prognosis in the intraoperative hyperglycemia and post-transplant infection groups (p = 0.234 and 0.059, respectively).

Conclusion: Intraoperative hyperglycemia is associated with the development of postoperative infections after lung transplantation. Patients with poor intraoperative blood glucose control may have an increased risk of postoperative infections. Intraoperative blood glucose management is crucial for improving the post-transplant clinical course.

肺移植术后术中高血糖与术后感染并发症的关系:一项单中心回顾性研究
目的:肺移植术后感染仍然是一个重要的问题。我们探讨了与肺移植术后感染相关的因素,包括术中高血糖。方法:选取46例肺移植患者作为研究对象。回顾性分析这些患者的背景及各因素与术后感染并发症的关系。在本研究中,术中高血糖被定义为术中平均血糖水平≥180mg /dL。结果:19例患者分为术中高血糖组。18例患者发生术后感染,术中高血糖组术后感染率高于非高血糖组。多因素分析显示,术中高血糖与肺移植术后感染独立相关(p结论:术中高血糖与肺移植术后感染的发生有关。术中血糖控制不良的患者术后感染的风险增加。术中血糖管理是改善移植后临床过程的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Surgery Today
Surgery Today 医学-外科
CiteScore
4.90
自引率
4.00%
发文量
208
审稿时长
1 months
期刊介绍: Surgery Today is the official journal of the Japan Surgical Society. The main purpose of the journal is to provide a place for the publication of high-quality papers documenting recent advances and new developments in all fields of surgery, both clinical and experimental. The journal welcomes original papers, review articles, and short communications, as well as short technical reports("How to do it"). The "How to do it" section will includes short articles on methods or techniques recommended for practical surgery. Papers submitted to the journal are reviewed by an international editorial board. Field of interest: All fields of surgery.
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