Surgery Today最新文献_第8页

Effect of surgical complications on outcomes of children with hepatoblastoma: a retrospective cohort study. 手术并发症对肝母细胞瘤患儿预后的影响：一项回顾性队列研究。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-08-16 DOI: 10.1007/s00595-024-02906-x

Masahiro Zenitani, Masanori Nishikawa, Ririko Takemura, Daichi Sakai, Masayuki Yoshida, Yuki Noguchi, Rei Matsuura, Satoshi Umeda, Noriaki Usui

{"title":"Effect of surgical complications on outcomes of children with hepatoblastoma: a retrospective cohort study.","authors":"Masahiro Zenitani, Masanori Nishikawa, Ririko Takemura, Daichi Sakai, Masayuki Yoshida, Yuki Noguchi, Rei Matsuura, Satoshi Umeda, Noriaki Usui","doi":"10.1007/s00595-024-02906-x","DOIUrl":"10.1007/s00595-024-02906-x","url":null,"abstract":"Purpose: This study aimed to investigate the incidence of severe surgical complications among children with hepatoblastoma, identify their risk factors, and evaluate the influence of surgical complications on long-term outcomes.Methods: Children with hepatoblastoma who underwent liver resection at our hospital between September 1992 and January 2023 were included in this study. Clinical data were retrospectively reviewed, and patients were categorized into complication and non-complication groups based on the need for radiological or surgical interventions or massive intraoperative blood loss (> 80 mL/kg).Results: Out of the 40 patients, 9 experienced severe complications (massive blood loss, n = 7; bile leakage, n = 3; and common bile duct stricture, n = 1). The participation of experienced liver surgeons was significantly greater in the non-complication group than in the complication group. The median duration from surgery to the start of postoperative chemotherapy was significantly shorter in the non-complication group than in the complication group. The overall 5-year survival rate was significantly higher in the non-complication group than in the complication group.Conclusion: Severe surgical complications were associated with a worse prognosis. An experienced liver surgeon should participate in technically demanding liver resections.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"197-204"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nipple reconstruction using spiral-peeling technique during oncoplastic breast-conserving surgery for a patient with small breasts. 在为小乳房患者进行肿瘤整形保乳手术时，使用螺旋剥离技术重建乳头。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-07-05 DOI: 10.1007/s00595-024-02892-0

Yuko Kijima, Munetsugu Hirata, Naotomo Higo, Yumika Nakazawa, Kazuya Shinmura

引用次数: 0

Predictive modeling for the germline pathogenic variant of the APC gene in patients with adenomatous polyposis: proposing a new APC score. 腺瘤性息肉病患者 APC 基因种系致病变体的预测模型：提出新的 APC 评分。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-07-06 DOI: 10.1007/s00595-024-02894-y

Misato Takao, Tatsuro Yamaguchi, Hidetaka Eguchi, Okihide Suzuki, Yoshiko Mori, Noriyasu Chika, Takeshi Yamada, Yasushi Okazaki, Naohiro Tomita, Tadashi Nomizu, Tomoyuki Momma, Tetsuji Takayama, Kohji Tanakaya, Kiwamu Akagi, Noriko Tanabe, Hideyuki Ishida

{"title":"Predictive modeling for the germline pathogenic variant of the APC gene in patients with adenomatous polyposis: proposing a new APC score.","authors":"Misato Takao, Tatsuro Yamaguchi, Hidetaka Eguchi, Okihide Suzuki, Yoshiko Mori, Noriyasu Chika, Takeshi Yamada, Yasushi Okazaki, Naohiro Tomita, Tadashi Nomizu, Tomoyuki Momma, Tetsuji Takayama, Kohji Tanakaya, Kiwamu Akagi, Noriko Tanabe, Hideyuki Ishida","doi":"10.1007/s00595-024-02894-y","DOIUrl":"10.1007/s00595-024-02894-y","url":null,"abstract":"Background: The precise diagnosis and medical management of patients with suspected familial adenomatous polyposis should be based on genetic testing, which may not always be available. Therefore, establishing a new model for predicting the likelihood of a germline pathogenic variant (GPV) of APC based on its clinical manifestations could prove to be useful in clinical practice.Methods: The presence of GPVs of APC gene was investigated in 162 patients with adenomatous polyposis (≥ 10 polyps) using a multigene panel or single-gene testing. To generate a predictive model for GPV of the APC gene, a logistic regression analysis was performed using the clinicopathological variables available at the time of the diagnosis of adenomatous polyposis.Results: Ninety (55.6%) patients had GPV of the APC gene. According to a multivariate logistic regression analysis, age < 40 years, polyps ≥ 100, fundic gland polyposis, and a family history of colorectal polyposis were found to be independent predictors of the GPV of APC and were used to establish a formula for predicting the GPV of APC using the four predictors. The prediction model had an area under the curve of 0.91 (0.86-0.96) according to a receiver operating characteristic analysis.Conclusion: The model for predicting the GPV of APC will help patients with adenomatous polyposis and physicians make decisions about genetic testing.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"229-237"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of preoperative skeletal muscle loss on the completion of S-1 adjuvant chemotherapy for gastric cancer. 术前骨骼肌缺失对完成胃癌 S-1 辅助化疗的影响。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-07-30 DOI: 10.1007/s00595-024-02902-1

Yudai Nakabayashi, Takuma Ohashi, Takeshi Kubota, Keiji Nishibeppu, Masayuki Yubakami, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Eigo Otsuji

{"title":"The impact of preoperative skeletal muscle loss on the completion of S-1 adjuvant chemotherapy for gastric cancer.","authors":"Yudai Nakabayashi, Takuma Ohashi, Takeshi Kubota, Keiji Nishibeppu, Masayuki Yubakami, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Eigo Otsuji","doi":"10.1007/s00595-024-02902-1","DOIUrl":"10.1007/s00595-024-02902-1","url":null,"abstract":"Purpose: Body weight loss after surgery for gastric cancer is related to S-1 compliance and it also affects the prognosis. However, it is unclear whether the preoperative skeletal muscle mass affects S-1 completion for gastric cancer. We investigated the impact of preoperative skeletal muscle mass loss on the completion of S-1 adjuvant chemotherapy for gastric cancer.Methods: We retrospectively analyzed data from 53 patients who underwent curative gastrectomy followed by adjuvant S-1 monotherapy for pStage II-III gastric cancer between 2012 and 2021 at our hospital. The psoas muscle mass index (PMI) was used as the index for preoperative skeletal muscle mass.Results: Thirty-six patients completed S-1 treatment and 17 discontinued treatment. The patients who completed S-1 treatment had a longer overall survival than those who discontinued treatment (log-rank test, p = 0.043). According to a univariate analysis, the patients in the discontinuation group had a significantly lower preoperative body mass index (< 22.9 kg/m2, p = 0.005) and a higher rate of adverse events (grade 2 or higher, p < 0.001) than those in the completion group. According to a multivariate analysis, preoperative PMI (HR 3.563, p = 0.030) was an independent predictive factor for S-1 completion.Conclusion: Preoperative skeletal muscle loss might therefore prevent the completion of adjuvant chemotherapy S-1 in patients with gastric cancer.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"238-246"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic factors for intraductal papillary neoplasm of the bile duct following surgical resection: a systematic review and meta-analysis. 手术切除后胆管导管内乳头状肿瘤的预后因素：系统回顾和荟萃分析。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-10-18 DOI: 10.1007/s00595-024-02948-1

Di Zeng, Bei Li, Nansheng Cheng

{"title":"Prognostic factors for intraductal papillary neoplasm of the bile duct following surgical resection: a systematic review and meta-analysis.","authors":"Di Zeng, Bei Li, Nansheng Cheng","doi":"10.1007/s00595-024-02948-1","DOIUrl":"10.1007/s00595-024-02948-1","url":null,"abstract":"Intraductal papillary neoplasm of the bile duct (IPNB) is a biliary neoplasm characterized by intraductal papillary growth and varying degrees of malignant transformation. This study aimed to identify effective prognostic factors (PFs) for predicting the prognosis of IPNB after surgical resection, addressing the gap in the higher level evidence. We systematically searched databases from their inception to October 10, 2023. Data on 12 predetermined PFs were collected and subjected to a meta-analysis. Forest plots were used to summarize the findings. Fifteen studies with a total of 2311 patients were included. Among the PFs examined, extrahepatic tumor location (HR, 2.97; 95% CI 1.68-5.23), subclassification type 2 (HR, 2.62; 95% CI 1.45-4.76), R1 resection (HR, 2.47; 95% CI 1.73-3.51), elevated CA19-9 level (HR, 3.25; 95% CI 1.91-5.54), tumor multiplicity (HR, 2.65; 95% CI 1.40-5.02), and adjacent organ invasion (HR, 3.17; 95% CI 2.01-5.00) were associated with a poorer prognosis. Additionally, the combined HR values indicated that lymph node metastasis and poor tumor differentiation were linked to a worse prognosis, although both exhibited significant heterogeneity. Our study offers valuable insights for enhancing postoperative prognostication and treatment decision-making for IPNB patients with IPNB. These findings warrant further validation in future prospective studies.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"131-143"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical significance of the maximum standardized uptake value on positron emission tomography to predict treatment response and outcomes in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy. 正电子发射断层扫描的最大标准化摄取值对预测接受新辅助化放疗的直肠癌患者的治疗反应和预后的临床意义。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-06-15 DOI: 10.1007/s00595-024-02880-4

Takao Tsuneki, Takeru Matsuda, Ryuichiro Sawada, Hiroshi Hasegawa, Kimihiro Yamashita, Yasufumi Koterazawa, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Shingo Kanaji, Yoshihiro Kakeji

{"title":"Clinical significance of the maximum standardized uptake value on positron emission tomography to predict treatment response and outcomes in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy.","authors":"Takao Tsuneki, Takeru Matsuda, Ryuichiro Sawada, Hiroshi Hasegawa, Kimihiro Yamashita, Yasufumi Koterazawa, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Shingo Kanaji, Yoshihiro Kakeji","doi":"10.1007/s00595-024-02880-4","DOIUrl":"10.1007/s00595-024-02880-4","url":null,"abstract":"Purposes: The association between the reduction rate of the maximum standardized uptake value (SUVmax) on positron emission tomography (PET) during neoadjuvant chemoradiotherapy (NACRT) and the prognosis in patients with locally advanced rectal cancer is unknown.Methods: We retrospectively analyzed 62 patients with locally advanced rectal cancer who underwent curative surgery after NACRT at Kobe University between 2008 and 2021. The SUVmax reduction rate was calculated from preoperative and postoperative PET scans, and its association with the prognosis was investigated.Results: The cutoff value for SUVmax reduction rate was 61.5%. Twenty patients had an SUVmax reduction rate > 61.5% (SUV responder group) and 38 patients had an SUVmax reduction rate ≤ 61.5% (SUV nonresponder group). Regarding pathological outcomes, the rate of a good histological response was significantly higher in the SUV responder group than in the SUV nonresponder group (80.0% vs. 21.1%, p < 0.001). Both the overall (OS) and relapse-free survival (RFS) rates were significantly better in the SUV responder group than in the SUV nonresponder group (OS, p = 0.035; RFS, p = 0.019). In the SUV responder group, only 1 case of recurrence was observed, with a median follow-up period of 56 months.Conclusion: The rate of SUVmax reduction during NACRT might predict the long-term prognosis of patients with locally advanced rectal cancer.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"154-161"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for and prognostic impact of lateral pelvic lymph node metastasis in patients with rectal neuroendocrine tumors: a single-center retrospective analysis of 214 cases with radical resection. 直肠神经内分泌肿瘤患者盆腔侧淋巴结转移的风险因素和预后影响：对214例根治性切除病例的单中心回顾性分析。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-08-28 DOI: 10.1007/s00595-024-02905-y

Tsubasa Sakurai, Y Hiyoshi, N Daitoku, S Matsui, T Mukai, T Nagasaki, T Yamaguchi, T Akiyoshi, H Kawachi, Y Fukunaga

{"title":"Risk factors for and prognostic impact of lateral pelvic lymph node metastasis in patients with rectal neuroendocrine tumors: a single-center retrospective analysis of 214 cases with radical resection.","authors":"Tsubasa Sakurai, Y Hiyoshi, N Daitoku, S Matsui, T Mukai, T Nagasaki, T Yamaguchi, T Akiyoshi, H Kawachi, Y Fukunaga","doi":"10.1007/s00595-024-02905-y","DOIUrl":"10.1007/s00595-024-02905-y","url":null,"abstract":"Purpose: Lateral pelvic lymph node (LPLN) metastasis of rectal neuroendocrine tumors (NETs) is rare, with unknown oncological features. We investigated the oncological impact of LPLN metastasis in patients with rectal NETs.Methods: This study included 214 patients with rectal NETs who underwent curative surgery. We evaluated their clinicopathological characteristics and short- and long-term outcomes.Results: LPLN dissection was performed in 15 patients with LPLN swelling ≥ 7 mm (preoperative imaging); 12 patients had LPLN metastases, 6 of whom had LPLN metastases without mesorectal lymph node metastases (skip metastasis). The short-term outcomes were similar between the groups with and without LPLN dissection. The median follow-up period was 59.4 months, and patients with LPLN metastasis showed significantly shorter disease-free and overall survival rates than those without metastasis. Among 199 patients who did not undergo LPLN dissection, only 1 had LPLN recurrence. In a univariate analysis, tumor depth, tumor grade, and LPLN metastasis were associated with the overall survival. In the multivariate analysis, only LPLN metastasis was an independent predictor of the overall survival.Conclusions: LPLN metastasis is a poor prognostic factor for patients with rectal NETs. LPLN enlargement can be considered an indication for dissection, owing to its high rate of metastasis and associated poor prognosis.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"144-153"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic accuracy of sentinel lymph node biopsy and wire localized clipped node biopsy after neoadjuvant chemotherapy in node-positive breast cancer. 淋巴结阳性乳腺癌新辅助化疗后前哨淋巴结活检和钢丝定位夹住淋巴结活检的诊断准确性。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-12-27 DOI: 10.1007/s00595-024-02981-0

Xinguang Wang, Qijun Zheng, Yingjian He, Yiqiang Liu, Ling Huo, Nan Zhang, Tianfeng Wang, Yuntao Xie, Jinfeng Li, Tao Ouyang, Zhaoqing Fan

{"title":"Diagnostic accuracy of sentinel lymph node biopsy and wire localized clipped node biopsy after neoadjuvant chemotherapy in node-positive breast cancer.","authors":"Xinguang Wang, Qijun Zheng, Yingjian He, Yiqiang Liu, Ling Huo, Nan Zhang, Tianfeng Wang, Yuntao Xie, Jinfeng Li, Tao Ouyang, Zhaoqing Fan","doi":"10.1007/s00595-024-02981-0","DOIUrl":"10.1007/s00595-024-02981-0","url":null,"abstract":"Purpose: The optimal method for axillary staging in patients with initially node-positive breast cancer after NACT remains unclear.Methods: We conducted a prospective, single-center trial to investigate the diagnostic performance of sentinel lymph node biopsy (SLNB) combined with wire localized lymph node biopsy (WLNB) of the clip-marked node as an axillary staging technique in patients with node-positive breast cancer after neoadjuvant chemotherapy (NACT).Results: A total of 233 patients were enrolled, 208 of whom were included in the analysis. The IR of SLNB and WLNB alone were 63.0% and 70.7%, respectively. The identification rate (IR) of targeted axillary dissection (TAD) was 87.5%. The FNR of and NPV were 6.9% (95% confidence interval [CI]:2.0-11.8%) and 92.0% (95% CI 86.3-97.7%), respectively, for the TAD procedure, 17.1% (95% CI 8.2-25.6%) and 83.3% (95% CI:74.7-91.9%) for SLNB alone, and 6.7% (95% CI:1.5-12.0%) and 90.6% (95% CI:83.5-97.7%) for WLNB alone.Conclusions: The diagnostic performance of TAD using wire localization was similar to that of the procedure performed using radioactive seed localization. (Clinical Trial Registration: NCT03715686).","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"172-179"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of peripheral blood test parameters predicting the response to palbociclib and endocrine therapy for metastatic breast cancer: a retrospective study in a single institution. 鉴定预测转移性乳腺癌患者对帕博西尼（palbociclib）和内分泌治疗反应的外周血检测参数：一项在单一机构进行的回顾性研究。

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-07-04 DOI: 10.1007/s00595-024-02893-z

Misato Yamamoto, Masahiro Shibata, Aya Tanaka, Nobuyuki Tsunoda, Norikazu Masuda

{"title":"Identification of peripheral blood test parameters predicting the response to palbociclib and endocrine therapy for metastatic breast cancer: a retrospective study in a single institution.","authors":"Misato Yamamoto, Masahiro Shibata, Aya Tanaka, Nobuyuki Tsunoda, Norikazu Masuda","doi":"10.1007/s00595-024-02893-z","DOIUrl":"10.1007/s00595-024-02893-z","url":null,"abstract":"Purpose: Cyclin-dependent kinase 4/6 inhibitors have been used in endocrine therapy for patients with estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer. Although randomized trials have shown that combined therapies prolong progression-free survival (PFS) in comparison to endocrine monotherapy, the predictors of efficacy are unknown. This study aimed to identify the blood test parameters to predict the effects of palbociclib and endocrine therapy.Methods: Seventy-nine patients treated with palbociclib and endocrine therapy between December 2017 and June 2022 were reviewed. We assessed PFS in patients according to factors evaluated based on patient characteristics and peripheral blood tests.Results: Patients in the C-reactive protein (CRP)-high, lactate dehydrogenase (LDH)-high, and albumin (Alb)-low groups had significantly shorter PFS than those in the normal group. A multivariate analysis revealed that high LDH and low Alb levels were independent factors that affected PFS. The Alb-low group had an inferior disease control rate. Patients in the CRP-high, LDH-high, and Alb-low groups who received these therapies as first- or second-line treatments showed poor PFS.Conclusions: Several predictors of the efficacy of palbociclib and endocrine therapy were identified in the peripheral blood test parameters of patients with ER-positive and HER2-negative subtypes of metastatic breast cancer.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"188-196"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of the COVID-19 pandemic on surgical treatment for thoracic malignant tumor cases in Japan: a national clinical database analysis. 新冠肺炎疫情对日本胸部恶性肿瘤手术治疗的影响：国家临床数据库分析

IF 1.7 4区医学

Surgery Today Pub Date : 2025-02-01 Epub Date: 2024-12-07 DOI: 10.1007/s00595-024-02907-w

Yasushi Shintani, Hiroyuki Yamamoto, Yukio Sato, Masayoshi Inoue, Keisuke Asakura, Hiroyuki Ito, Hidetaka Uramoto, Yoshinori Okada, Toshihiko Sato, Mariko Fukui, Yasushi Hoshikawa, Toyofumi Fengshi Chen-Yoshikawa, Masayuki Chida, Norihiko Ikeda, Ichiro Yoshino

{"title":"Effects of the COVID-19 pandemic on surgical treatment for thoracic malignant tumor cases in Japan: a national clinical database analysis.","authors":"Yasushi Shintani, Hiroyuki Yamamoto, Yukio Sato, Masayoshi Inoue, Keisuke Asakura, Hiroyuki Ito, Hidetaka Uramoto, Yoshinori Okada, Toshihiko Sato, Mariko Fukui, Yasushi Hoshikawa, Toyofumi Fengshi Chen-Yoshikawa, Masayuki Chida, Norihiko Ikeda, Ichiro Yoshino","doi":"10.1007/s00595-024-02907-w","DOIUrl":"10.1007/s00595-024-02907-w","url":null,"abstract":"Objective: Surgical care has been significantly affected by the COVID-19 pandemic. This study was conducted to evaluate the effects of the pandemic on lung cancer and mediastinal tumor surgery.Methods: Changes in the number of surgical procedures for lung cancer and mediastinal tumors were analyzed using the National Clinical Database of Japan. Patient characteristics, including disease stage and histological type, from 2019 to 2022 were evaluated using annual datasets.Results: Comparisons with 2019 showed that the number of patients who underwent surgery for primary lung cancer or a mediastinal tumor decreased in 2020 and then remained stable. There were no clinically significant changes in the trend over the four-year period regarding the number of patients for each clinical and pathological stage of lung cancer. Regarding mediastinal tumors, there was no significant difference in tumor size between years. There was a slight change in the selection of surgical indication during the second quarter of 2020, although its impact on annual trends in the stage distribution for lung cancer and primary disease for mediastinal tumors was minimal.Conclusions: Analyses of lung cancer and mediastinal tumor surgery cases in Japan during the COVID-19 pandemic showed no significant disease profile changes related to treatment delay.","PeriodicalId":22163,"journal":{"name":"Surgery Today","volume":" ","pages":"265-272"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0