Sustainable Chemistry and Pharmacy最新文献

{"title":"Eco-hydrogels: The new frontier of sustainability: A review","authors":"Alessio Ballarano ,&nbsp;Francesco Trotta ,&nbsp;Fabrizio Caldera ,&nbsp;Gjylije Hoti ,&nbsp;José Manuel López-Nicolás ,&nbsp;Adrián Matencio","doi":"10.1016/j.scp.2025.102223","DOIUrl":"10.1016/j.scp.2025.102223","url":null,"abstract":"<div><div>The growing demand for eco-friendly materials to address environmental, economic, and health challenges is rapidly shifting the focus of materials science toward natural and bio-based alternatives. Among these, eco-hydrogels have emerged as a promising class of materials due to their biodegradability, non-toxicity, and renewable origin.</div><div>This review goes beyond a mere summary of the literature by critically analyzing the sustainability potential of natural hydrogels compared to synthetic counterparts. We identify key knowledge gaps that hinder their large-scale application, including poor mechanical stability, lack of standardized green metrics, and limited scalability of production methods. Furthermore, we propose strategic directions to overcome these limitations, such as hybrid formulations, bio-inspired crosslinking, and lifecycle-based assessment tools.</div><div>By mapping current progress and critical bottlenecks, this work aims to guide future research toward the development of next-generation hydrogels that are not only high-performing, but also environmentally sustainable.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102223"},"PeriodicalIF":5.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green efficient approach for the synthesis of feruloylated acylglycerols using amberlyst-35 as a novel catalyst: optimization and function evaluation","authors":"Zhiheng Yuan ,&nbsp;Tingting Zhang ,&nbsp;Xinying Wang ,&nbsp;Shangde Sun ,&nbsp;Ahmed Ali Abd El-Maksoud","doi":"10.1016/j.scp.2025.102225","DOIUrl":"10.1016/j.scp.2025.102225","url":null,"abstract":"<div><div>Ferulic acid (FA) is a natural phenolic compound with antioxidant and UV-absorbing properties. However, its poor lipophilicity limits its application in lipid-based systems. In this study, a sustainable and efficient approach was proposed for synthesizing lipophilic feruloylated acylglycerols (FAGs). The reaction was carried out through the esterification of FA with glycerides, catalyzed by the heterogeneous cation exchange resin Amberlyst-35. A range of reaction variables, including pressure, catalyst type, acyl acceptor, temperature, catalyst dosage, and substrate molar ratio, were systematically investigated. The results showed that A-35 and glycerol monostearate (GMS) were identified as the optimal catalyst and acyl acceptor, respectively. Response surface methodology was used to optimize the process. Under mild vacuum conditions (105 °C, 18 % catalyst dosage, FA:GMS = 1:7, reaction time 16 h), the FAGs yield could reach as high as 95.01 %. Kinetic analysis indicated Arrhenius-type behavior with an activation energy of 58.96 kJ/mol. The obtained FAGs exhibited strong UV absorption (<em>λ_max</em> = 328 nm) and maintained more than 67 % photostability after 96 h of irradiation, which demonstrated its potential as a natural multifunctional additive. This study presents a practical method to produce lipophilic ferulic acid derivatives, helping develop sustainable ingredients for food and cosmetics.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102225"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a phosphorus waste-free switchable approach for the direct synthesis of alkyl azides from alcohols using magnetic phosphoryl azide nanoparticles","authors":"Negar Zekri ,&nbsp;Reza Fareghi-Alamdari ,&nbsp;Fatemeh Bazri ,&nbsp;Fariborz Mansouri","doi":"10.1016/j.scp.2025.102220","DOIUrl":"10.1016/j.scp.2025.102220","url":null,"abstract":"<div><div>A novel environmentally friendly protocol is presented for the synthesis of alkyl azides using phosphoryl azide-functionalized magnetic nanoparticles, prepared through a simple and scalable process from readily available precursors. These nanoparticles act as both nanoreagents and nanocatalysts in a one-pot transformation of alcohols to azides under mild conditions and short reaction times. The process eliminates the generation of phosphorus-containing waste while still benefiting from the incorporation of phosphine functionality in the activation of alcohols, marking a significant advancement in waste minimization and aligning with principles of green chemistry. Notably, the catalyst is magnetically recoverable, enabling easy and efficient recycling over multiple cycles without significant loss of activity, as confirmed by ICP analysis indicating minimal leaching of organic functional groups. This sustainable catalytic system offers several environmental benefits, including reduced hazardous waste and minimized reliance on stoichiometric phosphorus reagents. The strategy delivers high product yields and operational simplicity while significantly reducing the ecological footprint typically associated with azide synthesis.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102220"},"PeriodicalIF":5.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alum-Enhanced MICP for Sand Stabilization: Mechanisms and optimization","authors":"Zhiyang Shang ,&nbsp;Jie Peng ,&nbsp;Renjie Wei ,&nbsp;Liangliang Li ,&nbsp;Zhao Jiang ,&nbsp;Di Dai","doi":"10.1016/j.scp.2025.102122","DOIUrl":"10.1016/j.scp.2025.102122","url":null,"abstract":"<div><div>Microbial-induced calcium carbonate precipitation (MICP) is an environmentally friendly novel ground improvement technology. This study proposes an innovative alum-enhanced MICP technique to address critical challenges in traditional MICP applications for sand reinforcement, including prolonged construction duration, low treatment efficiency, and poor uniformity. Through systematic aqueous solution tests and sand column experiments, this study investigated the pH regulation mechanism of alum in MICP processes and its dual effects on calcium carbonate precipitation patterns and hydration product formation. Advanced characterization techniques including scanning electron microscope, X-ray diffraction, and fourier transform infrared spectroscopy were employed to elucidate the microstructural evolution. The results show that the addition of appropriate alum (3 mmol/L) significantly enhances the MICP effect through three synergistic mechanisms: (1) alum induced a shift in calcium carbonate crystallization from vaterite to calcite, resulting in a 180 % increase in calcite content. (2) analysis of variance results showed that alum addition significantly improved the spatial distribution uniformity of the precipitate, and (3) hydrocalumite, aluminum hydroxide, and calcium carbonate formed a framework cementation structure, which significantly improved the degree of cementation and strength of the specimens. Under these mechanisms, the addition of 3 mmol/L alum enabled the sand column to achieve stabilization after a single treatment cycle, reducing treatment time and cementation solution usage by over 70 % compared to conventional MICP. After five treatment cycles, the sand's strength showed an 851 % increase compared to the control group. The demonstrated techno-economic advantages highlight the potential of alum-enhanced MICP as a sustainable solution for sand ground improvement.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102122"},"PeriodicalIF":5.8,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alkali-activated waste seashell binder material: mechanical properties, reaction mechanism and life cycle assessment","authors":"Yuping Wu ,&nbsp;Jingzhou Lu ,&nbsp;Lifu Zhao ,&nbsp;Wenhui He","doi":"10.1016/j.scp.2025.102219","DOIUrl":"10.1016/j.scp.2025.102219","url":null,"abstract":"<div><div>The reactivity of binder materials and the hydration process are critical factors in the development of concrete properties. This paper utilizes discarded seashells as an assisted binder material to investigate the hydration reaction mechanism of seashell powder (SP) in an alkali-activated system, and to examine the mechanical properties of SP in different alkali activators. The experimental results show that the addition of shell powder increased the calcium ion concentration in the solution by nearly 50 %, effectively promoting the hydration reaction process of the alkali-activated system. Combined thermogravimetric (TG) test results indicate that nearly 40 % of SP participated in the hydration reaction. The mechanical properties of the mortar improved with the increase of SP content, and when the mortar containing 40 % SP was activated with a 1:2 mixture of activator, the maximum compressive strength at 28 days was 83.6 MPa and the maximum flexural strength was 8.9 MPa. Life cycle studies show that by optimizing the selection of alkali activators, alkali-activated concrete containing SP can not only reduce carbon dioxide emissions by 60 %, but also save 40 % in production costs.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102219"},"PeriodicalIF":5.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145159178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterogeneous catalysts for glycerol and glycol valorization via amination pathways","authors":"Daniil I. Lashchenko,&nbsp;Petr M. Yeletsky,&nbsp;Darya A. Konovalova,&nbsp;Anton P. Koskin,&nbsp;Sergey A. Stepanenko,&nbsp;Kristina A. Khrustova,&nbsp;Roman G. Kukushkin","doi":"10.1016/j.scp.2025.102214","DOIUrl":"10.1016/j.scp.2025.102214","url":null,"abstract":"<div><div>The processing of glycerol, as a by-product of biodiesel production, into valuable chemicals is a promising area from both economic and environmental perspectives. One of the approaches to glycerol valorization is the amination of glycerol and its derivatives (for example, propylene glycol), leading to the production of various amines with high added value. Ammonia, as well as primary and secondary amines can act as aminating agents. This review is devoted to the amination processes of various glycols and glycerol using heterogeneous catalysts.</div><div>Two main approaches to the catalytic amination process are considered: reductive amination in the presence of hydrogen and direct amination without the introduction of additional hydrogen. These approaches differ not only in the amination process mechanism but also in the nature of the catalyst and the process conditions. The traditional reductive amination catalysts are non-noble transition metals (Ni, Cu, and Co), noble metals (Ru, Pd, Pt, Rh, and Ir), or their combinations deposited on porous supports. Typical examples of direct amination catalysts are zeolites (e.g., Y, ZSM-5, and MOR) and porous acid oxides. For all cases, the general features of the processes of reductive and direct amination are considered, and specific examples are systematized. The key problems in this area are summarized, and the tasks necessary for the successful implementation of the valorization process of glycerol via the catalytic amination process are formulated.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102214"},"PeriodicalIF":5.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145118880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel sustainable strategies to mitigate toxicity of emerging contaminants: cellular and physiological insights from CMIT-exposed mussels treated with insect-based protein hydrolysates","authors":"Cristiana Roberta Multisanti ,&nbsp;Kristian Riolo ,&nbsp;Maria Giovanna Rizzo ,&nbsp;Federica Impellitteri ,&nbsp;Giuseppe Piccione ,&nbsp;Monia Perugini ,&nbsp;Alessia Giannetto ,&nbsp;Caterina Faggio","doi":"10.1016/j.scp.2025.102218","DOIUrl":"10.1016/j.scp.2025.102218","url":null,"abstract":"<div><div>The present interest in developing sustainable strategies to mitigate or prevent toxicity of emerging contaminants is attributable to their increasing occurrence in natural ecosystems. Beyond their established roles in the agri-food, feed, and biotechnology sectors, insects are emerging as valuable sources of bioactive compounds, highlighting their recognition as sustainable solutions in nutraceutical and pharmaceutical research. Therefore, the effects of protein hydrolysates from the black soldier fly, <em>Hermetia illucens</em> (BPHs) were evaluated against the toxicity induced by the methylchloroisothiazolinone (CMIT), a widely used biocides belonging to the isothiazolinones class of the biocides. Analyses focused on the modulation of key cellular and physiological parameters in <em>Mytilus galloprovincialis</em> exposed to CMIT (0.01 mg/L), BPHs (0.5 mg/mL), and their mix. Changes in haemocyte functions were assessed through cell viability assays and phagocytosis assay along with the expression of <em>γ-actin</em>; investigation into digestive gland (DG) functionality was carried out by measuring the viability of DG cells and their ability to perform osmoregulation after a hypotonic shock through the Regulatory Volume Decrease video-metric assay (RVD); antioxidant and cytoprotective responses were evaluated through the <em>Cu/ZnSOD, MnSOD, Hsp70,</em> and <em>CYP4Y1</em> gene expression analysis. Our findings showed that BPHs play a significant protective role against toxicity induced by CMIT in exposed mussels. Significant differences emerged between the control and the CMIT-treated groups, whereas a similar trend was observed between the CTRL and BSPHs-exposed groups. Groups exposed to the combinations (BPHs + CMIT) showed a recovery, suggesting the protective effect of this compound.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102218"},"PeriodicalIF":5.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced performance, synergistic mechanism, and better CO2 balance of loess solidification with magnesium cement-fly ash composite stabilizing agent","authors":"Qi Xu,&nbsp;Dongliang Chen,&nbsp;Xuerui Yan,&nbsp;Chunxi Hai,&nbsp;Yuan Zhou","doi":"10.1016/j.scp.2025.102217","DOIUrl":"10.1016/j.scp.2025.102217","url":null,"abstract":"<div><div>To address erosion on the ecologically fragile Loess Plateau, this study develops a green alternative to Portland cement-based solidifiers: magnesium oxysulfate cement (MOS) combined with industrial waste fly ash (FA), aligned with green chemistry principles. Physical tests show the MOS-FA composite notably optimizes loess porosity: for the MOS-15 %FA sample, pore volume decreases to 0.233 mL/g (31.4 % porosity, macropores 10.7 %, medium/small pores 28.8 %), and compressive strength rises from 1.3 MPa to 7.1 MPa. Microstructural analysis reveals hydration products (sheet-like Mg(OH)₂, flocculent M-S-H/M-A-S-H/C–S–H, acicular 5·1·7 phase) fill particle pores and form connections, with TG/DTG confirming silicate hydrates. The solidification mechanism relies on dual “chemical cementation (product encapsulation/entanglement) - physical filling (unreacted FA pore-filling)” effects, achieving particle bonding and microstructural densification to enhance mechanical properties. Under comparable strength requirements, MOS-FA exhibits superior carbon emission performance, underscoring its environmental sustainability for loess stabilization.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102217"},"PeriodicalIF":5.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of hydro-pumped and green hydrogen as energy storage processes: A case study on Kefalonia Island, Greece","authors":"A.-F. Papathanasiou,&nbsp;G. Pasaniotis,&nbsp;E. Baltas","doi":"10.1016/j.scp.2025.102216","DOIUrl":"10.1016/j.scp.2025.102216","url":null,"abstract":"<div><div>The present research work investigates the performance of two large-scale energy storage technologies: hydro-pumped storage (HPS) and green hydrogen production, within a hybrid renewable energy system (HRES) developed for Kefalonia Island, Greece. Given the island's seasonal water and electricity shortages driven by summer demand and limited infrastructure, the goal is to identify which storage option better supports local autonomy. Two scenarios, differing only in storage method, were simulated using identical wind input and desalination setup. Performance was evaluated based on climate and demand data, focusing on water and electricity needs. Both scenarios achieved 99.9 % potable water coverage. The HPS system exhibited notably higher energy efficiency (67 %) compared to hydrogen (33 %), and produced slightly more desalinated water, reaching 18,157,791 m³ versus 17,986,544 m³ respectively. Electricity demand coverage reached 77.8 % with HPS and 76.0 % with hydrogen, while irrigation demand was met by 80.2 % and 79.4 %, respectively. Seasonal storage analysis revealed pronounced summer depletion in both cases due to high demand and low wind availability, with HPS recovering faster and maintaining higher storage levels owing to lower energy losses. The comparison underscores the need for storage strategies adapted to island-specific water and energy dynamics. HPS is more efficient for short-to-medium-term needs, while green hydrogen offers potential for long-duration storage and deeper decarbonization.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102216"},"PeriodicalIF":5.8,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the hydration activity of steel slag-Portland cement composite by BES sodium activator","authors":"Lei Chang ,&nbsp;Suping Cui ,&nbsp;Jianfeng Wang ,&nbsp;Hui Liu ,&nbsp;Binjie Zhou","doi":"10.1016/j.scp.2025.102213","DOIUrl":"10.1016/j.scp.2025.102213","url":null,"abstract":"<div><div>The low hydration activity of steel slag (SS) limits its use in cement-based materials. The aim of this work was to explore the feasibility of N, N-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid (BES) sodium as a novel activator in enhancing the hydration of SS-Portland cement (PC) (mass ratio of 3:7) composite. The compressive strength and hydration process of SS-PC composite and the working mechanism of BES sodium were systematically investigated. The results showed that at low dose (0.1 %), BES sodium significantly enhanced the 3–28 d compressive strengths by 2.1–4.6 MPa. This enhancement stemmed from the simultaneous acceleration of aluminates (C₃A and C₁₂A₇), ferrites (C₄AF and C₂F), and silicates (C₃S and β-C₂S) hydration, and which facilitated the formation of ettringite (AFt), hemicarboaluminate (Hc), and C–S–H gels. At high dose (0.5 %), BES sodium did not affect the 3 d compressive strength and significantly increased the 7 and 28 d compressive strengths by 4.7 and 4.2 MPa. This was because the excessive acceleration of aluminates inhibited early silicates hydration. This inhibition gradually disappeared from 7 to 28 d. The activation mechanism involved BES sodium accelerated the dissolution and hydration of minerals via complexing to Ca²⁺, Al³⁺ and Fe³⁺, and its stronger complexation for Al³⁺ and Fe³⁺ explained the preferential acceleration for aluminates/ferrites. Crucially, using 0.1 % BES sodium can effectively reduce 0.221–0.234 tons of CO₂/ton SS-PC under the premise of 28 d compressive strength more than 42.5 MPa. This highlighted the potential of BES sodium as an effective activator in improving SS utilization by enhancing SS hydration activity.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102213"},"PeriodicalIF":5.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}