Sustainable Chemistry and Pharmacy最新文献

{"title":"Hydroxypropyl methylcellulose (HPMC) in sustainable pharmaceutical synthesis – Mechanistic insights, green metrics and outlook","authors":"Funmilayo Esther Mobilawon,&nbsp;Austine Ofondu Chinomso Iroegbu,&nbsp;Orpah Zinyemba,&nbsp;Reinout Meijboom","doi":"10.1016/j.scp.2025.102233","DOIUrl":"10.1016/j.scp.2025.102233","url":null,"abstract":"<div><div>The transition toward greener pharmaceutical manufacturing has heightened interest in water as a sustainable reaction medium. Hydroxypropyl methylcellulose (HPMC), a cost-effective and widely available cellulose derivative, has recently emerged as a micelle-mimicking additive capable of creating hydrophobic pockets that enhance solubility, reactivity and selectivity in aqueous systems. This review critically evaluates the role of HPMC in the synthesis of Active Pharmaceutical Ingredients (APIs), integrating mechanistic insights with sustainability metrics such as process mass intensity (PMI), E-factor and atom economy. Whereas previous reviews have largely cataloged applications, the present review highlights the advantages of HPMC, as a cost-effective and sustainable medium, contrasting it with designer surfactants such as TPGS-750-M and Savie, which – despite enabling notable progress – remain relatively costly and may still require co-solvents under certain conditions. Representative case studies in metal-catalyzed (Pd, Cu, Ni), metal-free (amide couplings, SNAr), and photoredox reactions are discussed, with emphasis on reaction efficiency at extremely short times, promising scalability, and environmental benefits. We further identify key limitations: restricted reaction scope and barriers to regulatory acceptance. By outlining critical research gaps and industrial opportunities, this work provides a forward-looking perspective on how HPMC can advance sustainable synthetic chemistry and accelerate the adoption of water-based technologies in pharmaceutical manufacturing.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102233"},"PeriodicalIF":5.8,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145268030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmentally sustainable technology for the treatment of electrolytic manganese residue: Enabling harmless disposal and utilization in building materials","authors":"Yu Xue ,&nbsp;Xiaoming Liu ,&nbsp;Zengqi Zhang ,&nbsp;Yinming Sun ,&nbsp;Huasheng Liao","doi":"10.1016/j.scp.2025.102224","DOIUrl":"10.1016/j.scp.2025.102224","url":null,"abstract":"<div><div>Electrolytic manganese residue (EMR) is an industrial solid waste discharged by the electrolytic manganese metal (EMM) industry with a growing stockpile that currently exceeds 160 million tons in China. EMR contains impurities and harmful ions such as Mn²⁺ and NH₄⁺ that cause severe environmental pollution. Fortunately, EMR also contains a high concentration of CaSO₄, similar to industrial gypsum, which makes EMR an alternative to gypsum in building materials. In addition, the harmful elements are stabilized and essentially eliminated when EMR is used as a building material. To facilitate future research with EMR, this paper provides a comprehensive review on the harmless treatment of EMR and its use as a building material. The harmless treatment methods for EMR include leaching (e.g., chemical, biological, electrochemical), solidification/stabilization (e.g., via chemical reagents or other industrial wastes) and roasting. The use cases of EMR as a building material include cement, concrete, bricks, road base materials, backfill materials, geopolymers, ceramic and ceramsite. After reviewing each of the aforementioned processes separately, their challenges and prospects are discussed together. Finally, several ways are proposed to better streamline current EMR research toward more efficient large scale industrial applications.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102224"},"PeriodicalIF":5.8,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145268029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of multi-industry solid waste synergistic low-carbon sustainable grouting material: Optimal regulation, diffusion characteristics, synergistic mechanism, and environmental and economic evaluation","authors":"Weize Sun,&nbsp;Qi Sun,&nbsp;Ziming Xu","doi":"10.1016/j.scp.2025.102231","DOIUrl":"10.1016/j.scp.2025.102231","url":null,"abstract":"<div><div>To address curtain seepage and multi-industry solid waste disposal, and advance environmental sustainability, a novel multi-industry solid waste synergistic low-carbon sustainable grouting material (MWLGM) was prepared using rice husk ash (RHA) after composite activation, ground granulated blast furnace slag (GGBFS) and steel slag (SS). Its formulation was optimized via response surface methodology combined with performance tests, and heavy metals were solidified. Tests and simulations were conducted to investigated heavy metal solidification efficiency, carbon emissions, phase composition and microstructure of MWLGM, as well as to reveal the synergistic mechanisms of strength formation and heavy metal solidification, and diffusion rules. The results revealed that MWLGM was 10 % RHA, 60 % SS, 30 % GGBFS, 0.4 water-cement ratio and 8 % alkali content, exhibiting 249 mm fluidity, 132min setting time, 22.37 MPa 28d uniaxial compressive strength (UCS), 1.8 MPa seepage pressure and 99.83 % stone formation rate. Raw materials in MWLGM acted synergistically, RHA provided [SiO₄]^4- as silicon source, SS suppled Ca²⁺ and mitigated shrinkage via micro-expansibility, GGBFS rapidly released Ca²⁺ and [AlO₄]^5-. Alkali-activation drove their reaction to form AFt and gels, and promote C(N)–S–H transformation to C(N)-(A)-S-H. These products not only enhanced the mechanical properties (early UCS by AFt, late by gels) and impermeability of MWLGM, but also solidifying heavy metals through physical encapsulation and chemical bonding below limits. Fe achieved 93.6 % solidification, Mn/Cu/Zn were fully solidified. Compared with OPC-based materials, MWLGM reduced carbon emissions by 20.3 % and cost by 9.29 %. It diffused circularly in hydrostatic grouting, and its diffusion shape shifted from ellipse to U-shape in dynamic-water grouting.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102231"},"PeriodicalIF":5.8,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urea-functionalized ionic polymeric materials with adjustable ion density for efficient CO2 fixation and iodine adsorption","authors":"Jiaojiao Zhao ,&nbsp;Ling Li ,&nbsp;Xiuli Yan ,&nbsp;Yongjing Hao ,&nbsp;Tao Chang","doi":"10.1016/j.scp.2025.102235","DOIUrl":"10.1016/j.scp.2025.102235","url":null,"abstract":"<div><div>Ionic polymeric materials have unique physical and chemical properties that make them crucial in the fields of catalysis and adsorption. This study successfully synthesized a series of urea-functionalized ionic polymeric materials, designated as UP-x (x = 2, 3, 4). The synthesis employed a simple solvothermal method in conjunction with a three-component condensation and the Menshutkin reaction, facilitating the precise incorporation of highly active urea units and the intentional modulation of ion density by varying the connecting monomers. The functional groups, microstructure, thermal stability and pore structure of the materials were characterized using FT-IR, ¹³C NMR, SEM, TGA and BET. Subsequently, these materials were applied in CO₂ fixation and iodine adsorption. All synthesized materials demonstrated effective catalytic activity, with UP-4 achieving a yield of up to 91.3 %. Experimental investigations have demonstrated that UP-4 is recyclable and can accommodate a wide range of substrates. Kinetic analyses revealed a reduction in the activation energy of the reaction to 50.5 kJ/mol. UP-x (x = 2, 3, 4) exhibited exceptional performance in the adsorption of iodine vapors, achieving maximum adsorption capacities of 4.51 g/g, 4.30 g/g, and 4.40 g/g, respectively. Results from DFT calculation confirm that the urea groups in the polymer framework can effectively activate epoxides and CO₂ molecules, thereby enhancing the cycloaddition reaction. The urea units, bromine ions, and aromatic rings serve as iodine adsorption sites, enabling efficient iodine capture. The adsorption mechanism of iodine vapor on these materials involves both physisorption and chemisorption.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102235"},"PeriodicalIF":5.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendations for making the European Commission's Safe and Sustainable by Design framework practicable for biocides","authors":"Merve Tunali ,&nbsp;Doris Voelker ,&nbsp;Corinna Burkart ,&nbsp;Kathrin Schwirn ,&nbsp;Bernd Nowack","doi":"10.1016/j.scp.2025.102221","DOIUrl":"10.1016/j.scp.2025.102221","url":null,"abstract":"<div><div>The European Commission has published a framework on Safe and Sustainable by Design (SSbD) to minimize the adverse impacts of chemicals and materials. Biocides are an important group of active substances with an intended effect on organisms that are widely used, both professionally and by the general public. With their intended effects on organisms, biocides represent a group of chemicals for which the SSbD framework presents particular challenges. As they intentionally feature harmful properties to provide a societal benefit, a special approach is needed for biocides to assess their safety and sustainability. Thus, we propose biocide-specific amendments to the SSbD framework to address these challenges, allowing a more balanced assessment. First of all, we suggest the inclusion of specific questions within the scoping analysis. In addition, a circular approach with central aspects is recommended for the assessment to facilitate an iterative improvement of safety and sustainability considerations for biocides. The central aspects include purpose, functionality and efficacy. Additionally, specific recommendations are provided for safety and sustainability individually, including the first proposals for biocide-specific aspects in the social impact assessment step; encompassing both societal needs and impacts (positive and negative aspects) and a socio-economic life cycle assessment. It is advisable to establish a feedback loop between societal needs and impacts and the intrinsic hazard assessment, which involves balancing the hazard with the functionality of the investigated biocide. Some suggestions from this study may also apply to other active substances, chemicals and materials, serving as general recommendations for the SSbD framework.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102221"},"PeriodicalIF":5.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced degradation of hydrocarbons without UV source: Efficiency of TiO2 and ZnO nanocatalysts","authors":"Karima Mahdi,&nbsp;Brahim Safi,&nbsp;Ahlem Kacel","doi":"10.1016/j.scp.2025.102222","DOIUrl":"10.1016/j.scp.2025.102222","url":null,"abstract":"<div><div>The study explores how two common metal oxides, titanium dioxide (TiO₂) and zinc oxide (ZnO), behave when used to clean drilling muds rich in petroleum hydrocarbons. Tests were carried out on a laboratory mixture of mineral oil and condensate, under visible light, using different catalyst loads (1, 5, and 10 g L⁻¹).</div><div>The outcomes were quite distinct for the two materials. TiO₂ only led to partial breakdown of the hydrocarbons, leaving behind several oxygenated fragments such as alcohols, ketones and acids. ZnO, on the other hand, showed a much stronger response: at 5 g L⁻¹ the hydrocarbon content dropped almost completely (≈99 % removal), and the carbon balance confirmed that most of the material had been converted into CO₂ and water.</div><div>Additional tests helped explain this difference. Radical trapping and oxygen purging experiments, supported by EPR and XPS analyses, indicated that ZnO contains more structural defects able to activate oxygen, which in turn leads to a higher production of reactive radicals. Microscopy also revealed clear surface changes on both materials after treatment.</div><div>From a practical point of view, the method is simple and does not involve organic solvents; the nanoparticles were recovered by centrifugation, and the overall energy requirement was modest (∼6.3 Wh per milligram of hydrocarbons removed). These results suggest that ZnO could be a reliable and sustainable option for treating oily wastes using only visible light, without the need for UV lamps.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102222"},"PeriodicalIF":5.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailoring mixed microbial consortia for sustainable biodiesel: An attempt towards synergistic biomass production and cost-effective harvesting in pilot scale open cultivation","authors":"Sarveshwaran Saravanabhupathy ,&nbsp;Sandipan Karmakar ,&nbsp;Rintu Banerjee","doi":"10.1016/j.scp.2025.102228","DOIUrl":"10.1016/j.scp.2025.102228","url":null,"abstract":"<div><div>Biodiesel has emerged as a viable alternative to traditional fossil fuels due to the growing need for sustainable energy sources. Microbial mixed-culture system was developed to avoid sterile and extremely harsh conditions practised in open algal cultivation. A series of culture conditions, including the suitable supplementation, inoculum and C/N ratios, were optimised to establish a robust and stable consortia. Optimal conditions yielded a maximum of 3.17 ± 0.27 g/L and 2.98 ± 0.16 g/L (a 2.36- and 2.32-fold increase) in biomass with a lipid content of 26 % and 22 % (a 2.89- and 2.56-fold increase in lipid) using <em>Chlorella minutissima</em> and <em>C. vulgaris</em> mediated mixed cultures, respectively, in an open cultivation than in axenic cultures. The photosynthetic microalgae form a mutualistic relationship with heterotrophic <em>Rhodococcus</em> sp. and <em>Aspergillus</em> sp. through O₂/CO₂ exchange. Supportive growth of microbes in consortia was visualised through microscopic observations. The constructed consortium demonstrated a substantial increase in biomass; its efficacy under open-cultivation was systematically evaluated in a pilot-scale open pond of 20-L. The consortia enabled a significant reduction of 75–83 % in harvesting costs, 3.62- to 6.23-fold reduction compared to axenic cultures. This work presents a practical approach for large-scale, sustainable microalgal cultivation that leverages cost-efficient nutrient sources and enhanced process economics. Notably, the fatty acid content analysed through gas chromatography resulted in considerable alteration in methyl ester produced through axenic and mixed culture systems in both closed and open conditions, with the majority of composition being C₁₆-palmitic, C₁₈-stearic and C_18:1-oleic acids, validating its suitability for biodiesel application, matching the standard requirements.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102228"},"PeriodicalIF":5.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Straightforward and greener synthesis of naturally occurring long chain alkylresorcinols","authors":"Amandine L. Flourat,&nbsp;Aurélien A.M. Péru,&nbsp;Nabila Imatoukene,&nbsp;Florent Allais","doi":"10.1016/j.scp.2025.102232","DOIUrl":"10.1016/j.scp.2025.102232","url":null,"abstract":"<div><div>Alkylresorcinols are natural phenolipids exhibiting interesting properties (e.g., antioxidant, anticancer). To monitor their bioproduction or quantify them in food samples, standards are required. However, due to their odd long alkyl chain (C &gt; 15), only a few synthetic routes are available, with the most efficient ones relying on the Wittig reaction. To provide a more sustainable synthetic route, two major modifications were implemented: (i) the starting material was changed from 3,5-dimethoxybenzaldehyde to 3,5-dibenzyloxybenzaldehyde, thereby eliminating the need for demethylation with highly toxic reagents such as BBr₃ or HBr; and (ii) the solvent system was replaced with greener and safer alternatives - cyclopentyl methyl ether and isopropyl alcohol - instead of the toluene, dimethyl sulfoxide, and dichloromethane used in previous publications. This strategy also enabled the replacement of a four-step sequence with two one-pot two-step reactions, resulting in good overall yields of 66 % and 60 % for C:19 and C:21 alkylresorcinols, respectively.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102232"},"PeriodicalIF":5.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural deep eutectic systems-based Ginkgo biloba extracts: A natural and sustainable solution for skin care","authors":"Marta Marques ,&nbsp;Ana Rita Jesus ,&nbsp;Ana Rita C. Duarte ,&nbsp;Alexandre Paiva","doi":"10.1016/j.scp.2025.102230","DOIUrl":"10.1016/j.scp.2025.102230","url":null,"abstract":"<div><div>This study explores not only the potential of hydrophilic Natural Deep Eutectic Systems (NADES) as sustainable extraction media for bioactive compounds from <em>Ginkgo biloba L.</em> leaves but also the potential of these extracts to be used in the development of skin care products with antioxidant properties. Three NADES were evaluated for their efficiency regarding total phenolic content (TPC) extraction yield and antioxidant activity. NADES LA:Glc:W (5:1:3) exhibited higher TPC extraction yield and antioxidant activity, surpassing even extraction with conventional solvent. Chemical characterization identified quinic acid and shikimic acid as the predominant compounds, with LA:Glc:W achieving the highest efficiency for quinic acid extraction. The extracts showed no cytotoxicity towards keratinocytes cells up to 50 mg/mL. The extracts were able to inhibit the formation of reactive oxygen species (ROS) after induction with H₂O₂ and UV light, highlighting their potential for skin care applications. The stability study showed that Bet:Suc:Gly:W extract was stable over 360 days, maintaining consistent TPC and antioxidant activity, demonstrating its potential for use in long-term storage and effective use in natural skincare formulations. Sustainability of our extraction method was confirmed through green analysis tools, AGREEprep and ComplexMoGAPI, in accordance with Green Analytical Chemistry principles.</div><div>The results presented herein, underscore the potential of NADES as eco-friendly alternatives for extracting and stabilizing bioactive compounds, with applications not only in cosmetic sciences but it also opens the opportunity to be used in other fields such as food and pharmaceuticals. This work demonstrates the critical importance of solvent selection in enhanced extraction efficiency, stability, and application-specific properties.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102230"},"PeriodicalIF":5.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning-driven prediction and multi-objective optimization of pyrolysis behavior for waste printed circuit boards","authors":"Yunfeng Zhu ,&nbsp;Bo Li ,&nbsp;Yonggang Wei ,&nbsp;Shiwei Zhou ,&nbsp;Hua Wang","doi":"10.1016/j.scp.2025.102227","DOIUrl":"10.1016/j.scp.2025.102227","url":null,"abstract":"<div><div>Predicting the pyrolysis behavior of waste printed circuit boards (WPCBs) and optimizing its parameters are crucial for establishing large-scale efficient pyrolysis systems for resource recovery. This study focuses on elucidating the pyrolysis mechanism, kinetics, and thermogravimetric analysis of WPCBs using model-free approaches and predicting pyrolysis behavior through machine learning (ML) models. The apparent activation energy (E_α) was determined to use the Flynne‒Walle<em>‒</em>Ozawa (FWO), Kissinger‒Akahira‒Sunose (KAS), and Friedman methods, which E_α of 175.29 kJ/mol, 174.38 kJ/mol and 170.67 kJ/mol for the three methods, respectively. The master plot method indicated that the pyrolysis reaction mechanism conforms to the chemical reaction model F3. The mass loss prediction model was developed based on four ML models, with the artificial neural network (ANN) model demonstrating superior performance (R² = 1, MSE = 24574 × 10⁻⁴). Multi-objective optimization based on the ANN model revealed that 500 °C and a heating rate of 10 °C/min represent the optimal operating parameters, simultaneously maximizing energy efficiency and minimizing environmental impact. The findings of this study provide fundamental and practical insights into the optimized pyrolysis of WPCBs.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"48 ","pages":"Article 102227"},"PeriodicalIF":5.8,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}