Sustainable Chemistry and Pharmacy最新文献

{"title":"Stimulation of calcium (Sodium)-alumina-silicate-hydrate (C(N)-A-S-H) gel by nano-alumina in the cleaner production of agro-based alkali-activated concrete","authors":"B. Swathi,&nbsp;R. Vidjeapriya","doi":"10.1016/j.scp.2025.102100","DOIUrl":"10.1016/j.scp.2025.102100","url":null,"abstract":"<div><div>The transition toward a circular economy has emphasized sustainable material practices, particularly through the principles of reducing, reusing, and recycling industrial by-products like Ground Granulated Blast furnace slag (GGBS) and agricultural by-products like rice husk ash (RHA). GGBS and RHA support the 3R's principle by reducing the need for cement, thereby lowering carbon emissions; reusing industrial and agricultural by-products; and recycling waste materials into valuable components for sustainable construction. Among these, RHA which is a siliceous residue from rice milling has shown promise as a supplementary cementitious material. This study investigates the feasibility of incorporating RHA and nano-alumina (NA), which are synthesized under low-emission conditions, into alkali-activated concrete (AAC) to enhance both performance and environmental sustainability. The research focuses on evaluating the physicochemical properties of RHA after thermal processing and assessing the influence of NA on geopolymerization reactions. Key experimental parameters included varying NA content (0–3 % by binder weight), monitoring compressive strength development, water contact angle measurements for wettability, and leaching tests for environmental safety. Nano-engineered properties like surface energy, pore reduction ability, and chemical stability are well examined through wettability and leaching which is the novelty. Results demonstrated that incorporating 2 % NA enhanced compressive strength by up to 16 % and increased the water contact angle by 54.8°, indicating improved resistance to moisture ingress. The matrix enhanced with nano-alumina demonstrated a strong ability to entrap heavy metals like arsenic, cadmium, lead, and zinc, reflecting its superior capacity for immobilization. The study elucidates the underlying geopolymer chemistry influenced by nano-alumina and highlights the potential of RHA and NA as viable components in sustainable concrete systems.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102100"},"PeriodicalIF":5.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailored biopolymer and its nanocomposites along with EPR frameworks under circular economy: A dual strategy for sustainable packaging solutions","authors":"Badal Dewangan,&nbsp;Mahak Mittal,&nbsp;Manjunath P. Eelager","doi":"10.1016/j.scp.2025.102092","DOIUrl":"10.1016/j.scp.2025.102092","url":null,"abstract":"<div><div>The widespread use of synthetic plastics in packaging while offering affordability and durability has led to severe environmental consequences, including persistent waste and rising greenhouse gas (GHG) emissions. This review critically examines bioplastics as a sustainable packaging alternative, integrating bibliometric mapping (VOSviewer), systematic literature analysis, and techno-economic assessments (TEA) to provide a data-driven overview. Key findings indicate that life cycle assessments (LCA) of PLA- and PHB-based materials report up to a 40 % reduction in greenhouse gas (GHG) emissions compared to conventional LDPE. These materials have achieved technology readiness levels (TRL) of 6–7 in various pilot-scale packaging applications, reflecting their progress toward commercialization. Chemical modifications and Nanotechnology-enabled reinforcement strategies have shown promising improvements in barrier properties and mechanical strength, addressing major commercialization barriers. The study also explores the policy landscape, noting that Extended Producer Responsibility (EPR) frameworks and circular economy regulations are gaining traction in regions such as the EU and India. Despite technological advancements, challenges such as high production costs, limited consumer awareness, and underdeveloped waste segregation systems persist. This review emphasizes the importance of aligning scientific progress with policy incentives and public outreach to increase market adoption. A strategic call-to-action is made for increased investment in scalable technologies, harmonized regulatory frameworks, and targeted R&amp;D to accelerate the transition towards a circular, bioplastic-driven economy. The findings provide a comprehensive roadmap for stakeholders to advance sustainable packaging solutions in both academic and industrial domains.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102092"},"PeriodicalIF":5.5,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simulation and optimization of CO2 mineralization for sustainable cement production","authors":"Reza Shahbaz ,&nbsp;Fatemeh Bahadori","doi":"10.1016/j.scp.2025.102099","DOIUrl":"10.1016/j.scp.2025.102099","url":null,"abstract":"<div><div>The cement industry is responsible for a significant portion of global CO₂ emissions, primarily due to the calcination of limestone and the combustion of fossil fuels—both of which result in unavoidable process-related emissionsGiven the scale and persistence of these emissions, conventional mitigation strategies are insufficient, underscoring the urgent need for advanced technologies such as carbon capture, utilization, and storage (CCUS). Among CCUS pathways, CO₂ mineralization offers a promising solution by converting carbon dioxide into stable mineral carbonates useable in construction materials. Furthermore, integrating alternative solid fuels and plastic waste in cement production, along with utilizing cement by-products as CO₂ absorbents, has gained increasing interest. This study simulates a CO₂ mineralization unit within a plug-flow reactor. The system is further extended to separate unreacted materials and products for potential reuse. Key operating parameters—pressure, temperature, molar ratios, and residence time—were systematically optimized. At 1 bar, 303 K, molar ratios of CO₂, KOH, and N₂ to CaCl₂ of 2.06, 4.05, and 7.08, respectively, and a residence time of 45.0 s, a CO₂ conversion of 98.3 % was achieved. The results demonstrate the potential of the proposed approach to significantly reduce the carbon footprint of cement manufacturing through effective CO₂ utilization. Furthermore, three different cases were evaluated through a comprehensive techno-economic analysis: Case 1 involved CO₂ sourced from SRF (Solid Recovered Fuel) with natural gas as the energy input; Case 2 considered CO₂ captured from a cement plant using natural gas; and Case 3 combined CO₂ from a cement plant with SRF as the energy source.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102099"},"PeriodicalIF":5.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In depth characterization of the addition of an alumina by-product into the magnesium phosphate cementitious matrix formulated with magnesium oxide by-product","authors":"S. Huete-Hernández,&nbsp;J.M. Chimenos,&nbsp;A. Alfocea-Roig,&nbsp;A. Alvarez-Coscojuela,&nbsp;J. Giro-Paloma,&nbsp;J. Formosa","doi":"10.1016/j.scp.2025.102097","DOIUrl":"10.1016/j.scp.2025.102097","url":null,"abstract":"<div><div>This study investigates the incorporation of an alumina-rich by-product, PAVAL®, into a magnesium phosphate cement matrix formulated with low-grade magnesium oxide (LG-MgO), aiming to valorize industrial residues while improving the sustainability of chemically bonded cements. The research focuses on characterising the potential chemical interaction between aluminium species in PAVAL® and the K-struvite matrix, and evaluating whether aluminium interacts with matrix providing a better bonding.</div><div>Micromortars containing up to 35 wt% PAVAL® were prepared and characterised using XRD, FTIR-ATR, BSEM-EDS, ²⁷Al and ³¹P MAS-NMR, and TG/DTG. The addition of PAVAL® significantly reduced the setting time from 84.5 min (0 wt% PAVAL®) to 16.5 min (35 wt% PAVAL®), which is a beneficial outcome for rapid applications, and enhanced compressive strength from 25.3 MPa (0 wt% PAVAL®) to a maximum of 40.5 MPa at 17.5 wt% PAVAL®. Although XRD and NMR did not confirm the formation of crystalline aluminophosphates, FTIR-ATR spectra showed phosphate band shifts, and BSEM-EDS mapping revealed Al-rich particles embedded within the K-struvite matrix, with signal overlap at particle boundaries.</div><div>³¹P MAS-NMR and TGA techniques confirmed the formation of amorphous Mg₂KH(PO₄)₂·15H₂O, increasing from 0.0 wt% (0 wt% PAVAL®) to 4 wt% (35 wt% PAVAL®). Concurrently, the K-struvite content decreased by 7.1 % compared with the theoretically expected amount in 35 wt% PAVAL mortars, while the Al(OH)₃ content also decreased by 3.5 % under the same comparison, suggesting partial solubilization and subsequent retention of aluminium as Al(OH)₄^- through interaction with phosphate species. These findings support Al may influence the matrix through physical embedding, surface adsorption or diffusion in matrix, although the formation of defined aluminophosphates remains inconclusive under the studied conditions.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102097"},"PeriodicalIF":5.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing granite waste aggregate content in self-compacting concrete using multi criteria decision approach","authors":"Abhishek Jain ,&nbsp;Mohammed Rihan Maaze ,&nbsp;Nishant Sachdeva ,&nbsp;Sandeep Chaudhary ,&nbsp;Rajesh Gupta","doi":"10.1016/j.scp.2025.102093","DOIUrl":"10.1016/j.scp.2025.102093","url":null,"abstract":"<div><div>This study aims to assess the technical, environmental, and multi-criteria performance of fly ash (FA) modified self-compacting concrete (SCC) incorporating granite waste aggregate (GWA). Nine SCC mixtures were developed by replacing cement with a constant 30 % FA and natural fine aggregate (NFA) with varying GWA contents ranging from 0 % to 60 %. Technical properties such as compressive strength, water permeability, water absorption, sorptivity, and chloride ion diffusion were evaluated. Results showed an increase in compressive strength of around 20 % with up to 40 % GWA incorporation. Mixtures containing up to 50 % GWA exhibited reductions in water permeability, water absorption, sorptivity (i.e., capillary rise), and chloride ion penetration by around 53 %, 15 %, 24 %, and 25 %, respectively, compared to the FA modified control SCC mix. SEM analysis confirmed a denser microstructure in SCC containing up to 50 % GWA. The environmental performance of SCC incorporating FA and GWA was evaluated through life cycle assessment (LCA), which indicated significant reductions in environmental impacts, like, 26 % in global warming potential, 23 % in mineral resource scarcity, 25 % in fossil resource scarcity, and 11 % in ozone formation. Additionally, multi-criteria decision-making (MCDM) analysis using both TOPSIS and VIKOR methods identified 30–35 % GWA as the optimal dosage for SCC mixes. Overall, SCC mixtures incorporating 30 % GWA demonstrated the most balanced performance, making them ideal for use in densely reinforced structural elements due to their enhanced technical and environmental benefits.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102093"},"PeriodicalIF":5.5,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extraction and optimization of sulforaphane using green methods from cruciferous vegetable seeds","authors":"Rabia Akçay-Salık ,&nbsp;Nazlı Böke-Sarıkahya ,&nbsp;Figen Kaymak-Ertekin","doi":"10.1016/j.scp.2025.102095","DOIUrl":"10.1016/j.scp.2025.102095","url":null,"abstract":"<div><div>Sulforaphane, a bioactive compound with numerous health benefits, has been extensively studied in recent years. This study reports the optimization of sulforaphane extraction from <em>Brassica</em> vegetable seeds. The optimum hydrolysis conditions and solvent concentrations for maximizing sulforaphane (SF) content were determined, with cabbage seeds yielding the highest SF content (875.19 μg/g DM). Process parameters for ultrasound, microwave, and hybrid ultrasound-microwave extraction methods were optimized and the optimum conditions for each method were found to be 100 W, 3 min, 25.95:1 (v/w) solvent/solid ratio for microwave assisted extraction; 40.24 % amplitude, 5.21 min, 24.02:1 (v/w) solvent/solid ratio for ultrasound assisted extraction, and 2.41 min ultrasound, 1 min microwave for hybrid ultrasound-microwave extraction. Among these methods, hybrid ultrasound-microwave extraction yielded the highest sulforaphane content (7662.47 μg/g DM) while maintaining relatively low extraction time and energy consumption demonstrating its potential as an efficient technique for bioactive compound extraction.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102095"},"PeriodicalIF":5.5,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible and cleaner alkaloid extraction of Sophora Flavescens and Heterosmilax Japonica with the aid of process analytical technology","authors":"Liping Liu ,&nbsp;Lin Miao ,&nbsp;Wenlong Li ,&nbsp;Tongchuan Suo","doi":"10.1016/j.scp.2025.102069","DOIUrl":"10.1016/j.scp.2025.102069","url":null,"abstract":"<div><div>Traditional alkaloid extraction processes (AEP) usually utilize large amount of organic reagents or acidic solvents, which produces considerable toxic/acidic solid and liquid waste. In order to make AEP cleaner, we take the extraction process of <em>Sophora Flavescens</em> and <em>Heterosmilax Japonica</em> as an instance and introduce process analytical technology (PAT) to analyze and improve the process. Specifically, we use near infrared spectroscopy (NIRS) to collect the process information. By combining NIRS data with online sampling and off-line high-performance liquid chromatography (HPLC) measurements, we find the hot leaching process (HLP) of the traditional AEP is quite inefficient and the extraction is quite incomplete. Hence, we make corresponding modifications to the process, including dropping the HLP step and introducing a three-phase static leaching step. Furthermore, we build predictive models using the NIRS and HPLC data in order to offer timely predictions of critical quality attributes (CQA), which makes it possible to perform dynamic controlling actions. With the help of PAT, we finally achieve flexible AEP which is cleaner and has higher extraction rate (<span><math><mrow><mo>∼</mo><mn>65</mn><mtext>%</mtext></mrow></math></span> more) and lower solvent consumption (<span><math><mrow><mo>∼</mo><mn>23</mn><mtext>%</mtext></mrow></math></span> less) than the traditional AEP. The flexible AEP also has much shorter processing time (<span><math><mrow><mo>∼</mo><mn>60</mn><mtext>%</mtext></mrow></math></span> less), which can lead to better energy consumption.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102069"},"PeriodicalIF":5.5,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental sustainability through adsorption: A review of chitosan's potential in dye pollution remediation","authors":"Prabhat Kumar Patel ,&nbsp;Ramagopal V.S. Uppaluri","doi":"10.1016/j.scp.2025.102096","DOIUrl":"10.1016/j.scp.2025.102096","url":null,"abstract":"<div><div>Globalization, growing population, and advancements in technology have catapulted the pollution issue to be a serious threat to the existence of most living beings on Earth. Consequently, sustainability has emerged as a key concern for policymakers worldwide. On a global basis, the release of several toxicants into the environment due to industrialization and community expansion is of serious concern. Enhanced and detrimental pollution is caused by dye, and this is scary as they are harmful, cannot be degraded easily, and they accumulate. To effectively mitigate the formation of such dyes in the water bodies, among several alternate pathways, biochemical adsorption has been thoroughly researched for its practical utility. Given its promising attributes, such as economic feasibility, accessibility, and compliance with environmental standards, this review article fosters the integration of three key dimensions in the mentioned research sub-theme. These refer to (a) systematic evaluation of various chitosan MOF composites with the MOF structures such as ZIF, UIO-66, MIL, and HKUST MOFs and their hybrid forms such as MOF-membranes, MOF-sponges, gels that were tailored for the dye capture purpose; (b) systematic assessment of the synthesis procedures and reaction mechanisms involved in chitosan MOF and other composite derivatives (hybrid materials) for the removal of toxic dyes from wastewater solutions and (3) assessment of the desorption efficiency, eluting solution efficacy and reusability of the chitosan MOF and other derivatives. Accordingly, future research directions have also been presented in the article for the development of efficient and scalable adsorption-based capture technologies for pollution-free environment realization.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102096"},"PeriodicalIF":5.5,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study on recovery and recycle of acid dye and silk fibroin from colored waste silk textiles through dye stripping and silk dissolution","authors":"Shun Fan,&nbsp;Luqman Jameel Rather,&nbsp;Jianyu Pu,&nbsp;Qing Li","doi":"10.1016/j.scp.2025.102090","DOIUrl":"10.1016/j.scp.2025.102090","url":null,"abstract":"<div><div>Effective recovery of dyes from discarded textiles is essential for energy conservation and environmental protection. This study explores recovery of acid dye from waste silk textiles through dye stripping and silk dissolution. Silk, wool and nylon fabrics were dyed with the recovered dye to explore optimal dyeing condition and the re-dyeing performance. A comparative analysis of the two recovery methods highlights their respective dyeing efficiencies and practical viability. Results show that dye stripping rate from fabric decolorization reaches 86 % when 50 % ethanol is used. An optimal dye uptake of over 95 % can be achieved when re-dyeing silk, wool and nylon with stripping dye. While fabric dye uptake from dissolved dye is relatively low (around 70 %), protein in the dissolved solution can play a certain role in modifying surface of the dyed fabric and in acting as leveling agent to ensure uniform coloration. A comparison of ternary solution of CaCl₂/ethanol/water and LiBr as silk dissolving agent reveals similar dyeing effects, with the ternary solution emerging as the more cost-effective alternative due to its significantly lower price. The printed patterns on cotton with regenerated colored protein from dissolved silk are vivid, sharp, and well-defined, exhibiting satisfactory colorfastness at protein content of 15 %. The successful application of recovered acid dye on cotton expands its potential use beyond traditional protein-based textiles. Both dye recovering methods employed in this study are simple, green and economical. The recovered dyes are able to retain the original dye structure. These findings provide valuable insights into a sustainable recovery and reuse of dyes from discarded textiles, offering practical implications for eco-friendly dyeing/printing practices and colored waste textile recycling.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102090"},"PeriodicalIF":5.5,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable nickel recovery: Advancing bioleaching techniques for secondary sources in renewable energy and circular economy applications","authors":"Heri Septya Kusuma ,&nbsp;Najla Anira Putri ,&nbsp;Azizah Maulana Farahita ,&nbsp;Hans Besian Manullang ,&nbsp;Debora Engeline Christa Jaya ,&nbsp;Andrew Nosakhare Amenaghawon ,&nbsp;Handoko Darmokoesoemo ,&nbsp;Mahfud Mahfud","doi":"10.1016/j.scp.2025.102094","DOIUrl":"10.1016/j.scp.2025.102094","url":null,"abstract":"<div><div>Nickel is an important metal with widespread applications in renewable energy technologies, electric vehicle batteries, and corrosion-resistant coatings. The increasing global demand for nickel, coupled with the depletion of primary ores and the environmental concerns associated with conventional extraction methods, underscores the necessity for sustainable recovery strategies. This review examines bioleaching as a promising eco-friendly alternative for nickel recovery from secondary waste sources, including spent catalysts, electronic waste, and electroplating sludge. It provides a detailed elucidation of bioleaching as a metal recovery strategy that utilizes the metabolic activities of acidophilic and heterotrophic microorganisms, such as <em>Acidithiobacillus ferrooxidans</em> and <em>Aspergillus niger</em>, to solubilize metals under low-energy and low-emission conditions. Recent advancements in bioleaching, including microbial adaptation, optimized process conditions, and hybrid recovery systems, and how they have significantly enhanced its efficiency, with nickel recovery rates reaching up to 100 % under optimized conditions were covered in detail. The review also provides a detailed discussion on the integration of advanced computational tools, such as machine learning and artificial intelligence to derive valuable insights from bioleaching processes, and this has further enhanced process optimization and performance. Additionally, findings from life cycle assessments (LCAs) have highlighted the environmental and economic benefits of bioleaching, particularly when combined with hydrometallurgical processes. It is reported that the utilization of mixed microbial consortia has demonstrated enhanced metal mobilization due to synergistic interactions. However, challenges such as slow leaching rates, microbial inhibition at high pulp densities, and the high cost of growth media persist, limiting large-scale industrial adoption. The transition from batch to continuous reactor systems, along with the utilization of low-cost organic substrates and genetically engineered microbial strains, are seen as viable solutions to address these limitations. Furthermore, the incorporation of omics-based approaches will offer deeper insights into microbial metabolism and metal-microbe interactions, paving the way for optimized bioleaching processes. This review synthesizes recent literature to highlight bioleaching as a scalable and sustainable technology for nickel recovery, providing critical insights for future research and industrial implementation.</div></div>","PeriodicalId":22138,"journal":{"name":"Sustainable Chemistry and Pharmacy","volume":"46 ","pages":"Article 102094"},"PeriodicalIF":5.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}