Smart Materials in Medicine最新文献_第3页

Plant-derived exosome-like nanoparticles as promising biotherapeutic tools: recent advances and challenges 植物源性外泌体样纳米颗粒作为有前途的生物治疗工具：最新进展和挑战

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-25 DOI: 10.1016/j.smaim.2025.07.003

Di Liu , Jingxian Gao , Xueling Wu , Lu Han

{"title":"Plant-derived exosome-like nanoparticles as promising biotherapeutic tools: recent advances and challenges","authors":"Di Liu , Jingxian Gao , Xueling Wu , Lu Han","doi":"10.1016/j.smaim.2025.07.003","DOIUrl":"10.1016/j.smaim.2025.07.003","url":null,"abstract":"<div><div>Exosomes, naturally occurring extracellular vesicles with diameters of 30–150 nm, have been extensively characterized in mammalian systems. In contrast, plant-derived exosome-like nanoparticles (PELNs) are emerging as versatile therapeutic carriers, offering distinct advantages including intrinsically low immunogenicity, inherent biocompatibility, enhanced biological barrier penetrability, and inherent cell-targeting capabilities. Notably, recent studies reveal that PELNs mediate unprecedented cross-kingdom communication by delivering plant-derived bioactive components to human cells, where they orchestrate immunomodulation, redox homeostasis, and tissue regeneration. This review systematically summarizes cutting-edge advances in PELNs research, emphasizing five critical dimensions: (1) context-dependent biogenesis pathways across plant species, (2) standardized isolation protocols combining ultracentrifugation and density gradient separation, (3) compositional profiles (proteins/lipids/nucleic acids/metabolites), (4) cellular internalization mechanisms, and (5) engineered applications as precision drug delivery platforms. We particularly highlight innovations in PELNs functionalization strategies - including chemical modification, genetic engineering, and biomimetic membrane hybridization - that enhance payload capacity and site-specific delivery. While discussing current limitations such as scalable production bottlenecks and pharmacokinetic characterization gaps, we summarize emerging strategies that aim to bridge botanical nanobiology and clinical practice. By delineating structure-function correlations and quality control standards, this critical review provides insights that may accelerate the development of PELN-based next-generation nanomedicines, ultimately fostering their transition from laboratory breakthroughs to FDA-approved therapeutic solutions.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 285-304"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144865840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two-dimensional materials for anti-inflammatory applications 抗炎应用的二维材料

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1016/j.smaim.2025.07.002

Rui Liu , Xinxin Zhang , Zhengbao Zha , Cheng-Yan Xu , Zhaohua Miao

{"title":"Two-dimensional materials for anti-inflammatory applications","authors":"Rui Liu , Xinxin Zhang , Zhengbao Zha , Cheng-Yan Xu , Zhaohua Miao","doi":"10.1016/j.smaim.2025.07.002","DOIUrl":"10.1016/j.smaim.2025.07.002","url":null,"abstract":"<div><div>Due to unique physicochemical properties including high surface-to-volume ratio, abundant active sites, and tunable surface functionalities, two-dimensional (2D) materials have emerged as an intriguing platform for anti-inflammatory therapy. This review comprehensively explores the physicochemical characteristics, types, and anti-inflammatory mechanisms of representative 2D materials, including MXenes, black phosphorus (BP), transition metal dichalcogenides (TMDs), boron nitride (BN), metal-organic frameworks (MOFs), and layered double hydroxides (LDHs). These materials exhibit intriguing anti-inflammatory mechanisms, such as scavenging reactive oxygen/nitrogen species (ROS/RNS), regulating cytokine networks, inhibiting pro-inflammatory signaling pathways, and promoting macrophage polarization. Furthermore, their applications in treating diverse inflammatory diseases are summarized, including accelerated wound healing via ROS elimination, colitis therapy through gut microbiota modulation, mitigation of acute kidney injury (AKI) via oxidative stress reduction, and rheumatoid arthritis (RA) and neurodegenerative disorders treatment via neuroimmune regulation. Critical challenges in clinical translation, such as biodegradability and long-term biocompatibility, are addressed. This review underscores the vital role of 2D anti-inflammatory materials in bridging material science with biomedical field, offering insights into the design of future anti-inflammatory drugs.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 205-224"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in shape memory polymers for biomedical applications: Bridging macro- and micro-scale effects 生物医学用途的形状记忆聚合物的最新进展：桥接宏观和微观尺度效应

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-11 DOI: 10.1016/j.smaim.2025.06.001

Dongqi You , Lining Lin , Minyi Dong , Yunhong Wu , Yijie Hu , Xinyue Hu , Yangjie Shao , Yuan Xie , Menghan Xu , Guancong Chen , Rong Lan , Haiying Ma , Yunting Zhou , Huiming Wang , Binjie Jin , Mengfei Yu

{"title":"Recent advances in shape memory polymers for biomedical applications: Bridging macro- and micro-scale effects","authors":"Dongqi You , Lining Lin , Minyi Dong , Yunhong Wu , Yijie Hu , Xinyue Hu , Yangjie Shao , Yuan Xie , Menghan Xu , Guancong Chen , Rong Lan , Haiying Ma , Yunting Zhou , Huiming Wang , Binjie Jin , Mengfei Yu","doi":"10.1016/j.smaim.2025.06.001","DOIUrl":"10.1016/j.smaim.2025.06.001","url":null,"abstract":"<div><div>Shape memory polymers (SMPs) are a class of materials capable of undergoing deformation in response to external stimuli, and their unique shape-changing properties offer vast potential for applications in the biomedical field. Based on the dimensionality of the shape memory effect (SME), deformation can be categorized into macroscopic and microscopic levels. Macroscopic deformation enables SMPs to perform functions such as adaptation, filling, and support through overall structural changes. On the other hand, microscopic deformation involves dynamic modulation of the surface morphology of micro- and nanoscale scaffolds, influencing cell morphology and further regulating cell behavior and fate. Whether at the macroscopic or microscopic level, SME significantly enhances the performance of SMPs as tissue scaffolds or medical devices. This review summarizes the progress of SMP applications in the biomedical field, focusing on SME at different dimensional levels, and provides insights into future development directions.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 240-269"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced oxygen therapeutics for treatments of acute hemorrhagic shock and organ preservation 先进的氧疗法治疗急性失血性休克和器官保存

Smart Materials in Medicine Pub Date : 2025-06-01 Epub Date: 2025-04-18 DOI: 10.1016/j.smaim.2025.04.001

Qinqi Wang , Jiazhen Yang , Meng Sun , Lei Dang , Liana Shestakova , Youry Ostrovsky , Wenliang Li , Leijiao Li , Jianxun Ding

{"title":"Advanced oxygen therapeutics for treatments of acute hemorrhagic shock and organ preservation","authors":"Qinqi Wang , Jiazhen Yang , Meng Sun , Lei Dang , Liana Shestakova , Youry Ostrovsky , Wenliang Li , Leijiao Li , Jianxun Ding","doi":"10.1016/j.smaim.2025.04.001","DOIUrl":"10.1016/j.smaim.2025.04.001","url":null,"abstract":"<div><div>Oxygen (O<sub>2</sub>) is vital in respiratory process that maintains biological balance in mammals. O<sub>2</sub> therapeutics treat ischemic tissues by facilitating O<sub>2</sub> transport and alleviating cellular hypoxia. The development of O<sub>2</sub> carriers focuses on their interactions with molecular O<sub>2</sub> to achieve therapeutic effects. This review examines the distinct O<sub>2</sub>-carrying mechanisms of hemoglobin-based oxygen carriers (HBOCs) and fluorocarbon-based oxygen carriers (FBOCs), emphasizing their chemical and physical differences. The rational design of O<sub>2</sub> carriers for biomedical applications and recent research advances are discussed, focusing on their therapeutic use in acute hemorrhagic shock and organ preservation. Moreover, this review highlights the need to explore the biomedical mechanisms underlying O<sub>2</sub> therapeutics further, offering insights for improving O<sub>2</sub>-carrying capacity and optimizing their applications in medicine.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 139-151"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143943533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Light-responsible ECM-mimetic scaffolds for neural differentiation. Intracellular versus extracellular photothermal stimulation 用于神经分化的光负责型ecm模拟支架。细胞内与细胞外光热刺激

Smart Materials in Medicine Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.1016/j.smaim.2025.02.002

Оlga Y. Аntonova, Olga Y. Kochetkova, Maxim Tailakov, Igor L. Kanev

{"title":"Light-responsible ECM-mimetic scaffolds for neural differentiation. Intracellular versus extracellular photothermal stimulation","authors":"Оlga Y. Аntonova, Olga Y. Kochetkova, Maxim Tailakov, Igor L. Kanev","doi":"10.1016/j.smaim.2025.02.002","DOIUrl":"10.1016/j.smaim.2025.02.002","url":null,"abstract":"<div><div>The development of approaches and materials that combine several types of stimulatory effects on nerve tissue growth is a promising task for biotechnology. The aim of this work was a comparative study of the influence of intracellularly and extracellularly localized polydopamine-containing materials on the heat-mediated facilitation of neuronal differentiation. Scaffolds made from aligned nylon nanofibers, mimicking the structure of the extracellular matrix, were used as a matrix for immobilizing photothermal nanoparticles. The composite material combines an ultrastructure capable of accelerating and directing the growth of nerve extensions and the ability for controlled thermal remote influence on cell activity under NIR irradiation within the biological transparency range. The materials demonstrated high photostability and biocompatibility without the drawbacks associated with intracellular nanoparticle delivery, such as cytotoxicity and gradual elimination from the body. The immobilization of thermoplasmonic elements on the fibers surface allows for more controlled and manageable heating compared to intracellular introduction of PDA nanoparticles. The fibrous material's ultrastructure directs neurite growth and enhances elongation. Photothermal stimulation further enhances this process by increasing the proportion of cells with longer neurites, thus enhancing neuronal differentiation. Composite nanomaterials can be used for neuromodulation, managing the functional activity of cells, particularly where directed growth is needed, such as in the regeneration of peripheral nerve tissue. This work brings us closer to the creation of smart materials that are biocompatible and easy to manufacture for developing scalable thermal stimulation techniques in regenerative medicine.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 1","pages":"Pages 8-22"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The cardiac electrophysiology-inspired patches for repairing myocardial infarction: A review 心脏电生理激励贴片修复心肌梗死的研究进展

Smart Materials in Medicine Pub Date : 2025-03-01 Epub Date: 2025-01-04 DOI: 10.1016/j.smaim.2024.12.003

Songtao Zhang , Ziyi Shao , Yihong Wu , Yongyi Song , Yaxi He , Zongyi Liu , Xiaodong Fu , Leyu Wang

{"title":"The cardiac electrophysiology-inspired patches for repairing myocardial infarction: A review","authors":"Songtao Zhang , Ziyi Shao , Yihong Wu , Yongyi Song , Yaxi He , Zongyi Liu , Xiaodong Fu , Leyu Wang","doi":"10.1016/j.smaim.2024.12.003","DOIUrl":"10.1016/j.smaim.2024.12.003","url":null,"abstract":"<div><div>Myocardial infarction has been a serious threat to human health due to its high morbidity and mortality all over the world. The major problem is the loss of limited regenerative cardiomyocytes and occurrence of inflammatory response, leading to the formation of non-contractile and non-conducting fibrotic scar tissue. Thus, it disrupts the mechano-electric coupling system of the heart, negatively influencing the heart function. Recently, the conductive cardiac patches with advantage of reconstructing electrical propagation have been extensively applied for cardiac repair. This review introduces a detailed overview of the recent progress in cardiac electrophysiology-inspired patches for cardiac repair from three parts of the construction and functionality of mechano-electric coupling cardiac patches, the construction and functionality of microstructure of the cardiac patches, the realtime detection based on mechano-electric transformation. Finally, the achievements and future perspective of conductive cardiac patches is discussed from the aspects of biosafety, further exploration of factors affecting mechano-electric coupling in cardiac patches and regulation of detection. It is hopeful to help researchers understand the functional components and development of conductive cardiac patches for cardiac repair, as well as to inspire them to synthesize novel cardiac patches for promoting clinical translation.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 1","pages":"Pages 108-119"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in graphene-based composites: A review of the emerging applications in healthcare 石墨烯基复合材料的进展：在医疗保健中的新兴应用综述

Smart Materials in Medicine Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI: 10.1016/j.smaim.2025.01.001

Farwa Batool , Saz Muhammad , Rabia Muazzam , Muhammad Waqas , Zia Ullah , Shubham Roy , Yinghe Zhang , Ke Wang , Bing Guo

{"title":"Advancements in graphene-based composites: A review of the emerging applications in healthcare","authors":"Farwa Batool , Saz Muhammad , Rabia Muazzam , Muhammad Waqas , Zia Ullah , Shubham Roy , Yinghe Zhang , Ke Wang , Bing Guo","doi":"10.1016/j.smaim.2025.01.001","DOIUrl":"10.1016/j.smaim.2025.01.001","url":null,"abstract":"<div><div>Graphene and related materials are emerging revolutionary materials due to fascinating stimuli-responsive physiochemical properties having widespread applications in developing advanced nano-systems for detection, diagnostics, and therapeutics in biomedical fields. Various materials like metal nanoparticles, polymers, dyes, drugs, and proteins could be combined yielding graphene-based composite materials (GBCMs) to synergistically fulfill different biomedical requirements. The 2D conjugated structure, easy surface functionalization <em>via</em> covalent or van der Waal interactions, and combination with different components for versatile functionalities altogether contribute to the development of GBCM for healthcare applications. This review specifically focuses on GBCMs and discusses specific material properties relevant to their material applications in healthcare. Furthermore, the synthesis, toxicity, and biocompatibility of these GBCMs, and their interactions with biological materials are thoroughly discussed. Importantly, the recent cutting-edge applications in the field of healthcare, including its role in the development of antibacterial, anti-viral, and photothermal therapies, wound healing, drug delivery, neurodegenerative disease therapy, and biosensing based on GBCMs are well-updated. Additionally, the applications of GBCMs in point-of-care devices, wearable electronics, and tissue engineering are well summarized. We hope this review opens up more possibilities to design more innovative healthcare materials derived from graphene.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 1","pages":"Pages 120-138"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomimetic 3D printing of photocrosslinkable biodegradable elastomers-modified hybrid scaffolds as instructive platforms for bone tissue regeneration 光交联可生物降解弹性体改性复合支架的仿生3D打印作为骨组织再生的指导平台

Smart Materials in Medicine Pub Date : 2025-03-01 Epub Date: 2024-12-18 DOI: 10.1016/j.smaim.2024.12.001

Panyu Zhou , Jiayi Wang , Hongrui Wang , Hao Pan , Hengsong Shi , Yu Fu , Yuan Yuan , Yang Wang , Qi Gan , Changsheng Liu

{"title":"Biomimetic 3D printing of photocrosslinkable biodegradable elastomers-modified hybrid scaffolds as instructive platforms for bone tissue regeneration","authors":"Panyu Zhou , Jiayi Wang , Hongrui Wang , Hao Pan , Hengsong Shi , Yu Fu , Yuan Yuan , Yang Wang , Qi Gan , Changsheng Liu","doi":"10.1016/j.smaim.2024.12.001","DOIUrl":"10.1016/j.smaim.2024.12.001","url":null,"abstract":"<div><div>3D printing is regarded as an ideal method for large-scale bone defect repair. A rapid curing rate and strong mechanical properties throughout the product's shelf life are key development goals in 3D-printed bone repair biomaterials. To achieve this goal, we developed a 3D-printable organic/inorganic composite ink featuring rapid curing and highly customizable properties. After 3D printing, the nanocomposite ink of poly (glyceryl sebacate)-2-chlorocinnamoyl chloride/β-tricalcium phosphate (PGS-CC/β-TCP) undergoes short-term light crosslinking to form a biomimetic network of inorganic-organic composite materials. The resulting bone repair scaffold possesses excellent mechanical properties, significantly promotes cell adhesion and proliferation, and demonstrates good <em>in vitro</em> osteogenic activity, angiogenic performance, and mineralization capability. Moreover, the PGS-CC/β-TCP 3D-printed scaffold exhibits good degradation performance, retaining its mechanical properties even after four weeks of degradation. The PGS-CC(1:2)/β-TCP composite scaffold can effectively repair severe cranial bone defects in rats, showing optimal <em>in vivo</em> osteogenic and degradation performance at 6 and 12 weeks. With these advantages, this innovative 3D-printed biomaterial has great clinical application prospects for large segment bone repair and provides new opportunities for other complex reconstructions.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 1","pages":"Pages 95-107"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soft bioelectronics for the diagnosis and treatment of heart diseases 软性生物电子学用于心脏疾病的诊断和治疗

Smart Materials in Medicine Pub Date : 2025-03-01 Epub Date: 2024-12-15 DOI: 10.1016/j.smaim.2024.12.002

Guangbo Ji , Wenjin Li , Yian Su , Tianjiao Cao , Meng Qian , Huan Wang , Qiang Zhao

引用次数: 0

Bright antimicrobial surfaces based on Schottky interfaces: From light illumination to bacterial charging 基于肖特基界面的明亮抗菌表面：从光照到细菌充电

Smart Materials in Medicine Pub Date : 2025-03-01 Epub Date: 2025-02-07 DOI: 10.1016/j.smaim.2025.02.001

Zubair Ahmed , Zhong Wang , Muhammed Adil , Ijaz Ahmad Bhatti , Huiliang Cao

{"title":"Bright antimicrobial surfaces based on Schottky interfaces: From light illumination to bacterial charging","authors":"Zubair Ahmed , Zhong Wang , Muhammed Adil , Ijaz Ahmad Bhatti , Huiliang Cao","doi":"10.1016/j.smaim.2025.02.001","DOIUrl":"10.1016/j.smaim.2025.02.001","url":null,"abstract":"<div><div>The growing threat of resistant bacterial infections is a global concern. Therefore, it is crucial to discover new antimicrobial agents or alternative mechanisms to address this issue. This article explores the potential of smart antimicrobial surfaces based on Schottky interfaces for mitigating bacterial infections. The article proposes combining the biological features of bacterial cells with the physics of Schottky-Mott theory to describe and explain the disinfection behaviors of Schottky interfaces. The physicochemical properties and associated characterization methods of Schottky interfaces are examined to uncover their smart pathways leading to disinfection. The fabrication of antimicrobial Schottky interfaces is explored, focusing on techniques such as sputtering, evaporation, chemical deposition, and ion implantation. The advantages and challenges of each method are highlighted, along with recent research on their use to create antimicrobial surfaces over different activating procedures, ranging from light adsorption to bacterial charging and capacitive charge storage. Overall, this article provides a comprehensive overview of the knowledge and advancements in smart antimicrobial surfaces based on Schottky interfaces, emphasizing their potential in combating bacterial infections and offering insights into their properties, fabrication, and applications. The article concludes by illuminating the need for additional research to completely understand the dark behaviors of Schottky interfaces against microbes and harness their full potential in smart coating developments.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 1","pages":"Pages 67-94"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0