Smart Materials in Medicine最新文献_第2页

Self-adhesive and conductive hydrogel based on MIL-53 (Fe)-anchored graphene oxide for bioelectronics and wound healing 基于MIL-53 （Fe）锚定氧化石墨烯的自粘导电水凝胶用于生物电子学和伤口愈合

Smart Materials in Medicine Pub Date : 2025-12-01 Epub Date: 2025-11-28 DOI: 10.1016/j.smaim.2025.11.003

Jialiang Zhao , Xuanhan Lv , Ying Chen, Xiong Lu, Chaoming Xie

{"title":"Self-adhesive and conductive hydrogel based on MIL-53 (Fe)-anchored graphene oxide for bioelectronics and wound healing","authors":"Jialiang Zhao , Xuanhan Lv , Ying Chen, Xiong Lu, Chaoming Xie","doi":"10.1016/j.smaim.2025.11.003","DOIUrl":"10.1016/j.smaim.2025.11.003","url":null,"abstract":"<div><div>The integration of bioelectronics with biological tissues remains challenging due to mechanical and interfacial mismatches. In addition, existing bioelectronic hydrogels typically exhibit monofunctional characteristics and cannot achieve integrated wound monitoring and healing capabilities. There is an urgent need for multifunctional hydrogels that combine reliable bioelectronic sensing with active tissue repair properties. Here, we report a MIL-53 (Fe) metal-organic framework (MOF)-loaded polydopamine (PDA)-mediated graphene oxide (PGO)-incorporated polyacrylamide (PAM) hydrogel. The catechol groups of PDA strongly coordinate with the Fe sites of MIL-53 MOF, anchoring the MIL-53 MOF onto the PGO sheets and improving its dispersion. The incorporation of MIL-53@PGO significantly enhances the hydrogel's mechanical properties, electrical conductivity, and tissue adhesion. The hydrogel exhibits exceptional bioelectronic performance, enabling high-fidelity electromyographic signal acquisition in vivo and acting as a highly efficient capacitor with a specific capacitance as high as 159.4 mF/g. Furthermore, At the same time, due to the good energy storage function of MIL-53 MOF, it can provide electrons for PGO after its addition, enhancing antioxidant capacity and immunomodulatory effects, and promoting electrical stimulation-mediated cell regulation. This work presents a promising strategy for developing next-generation bioelectronic hydrogels that achieve integrated sensing and therapeutic functionalities for advanced healthcare applications.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 3","pages":"Pages 406-416"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart polymeric nanoparticles for targeted delivery and microenvironment-responsive therapy in pancreatic cancer 用于胰腺癌靶向递送和微环境反应治疗的智能聚合物纳米颗粒

Smart Materials in Medicine Pub Date : 2025-12-01 Epub Date: 2025-10-01 DOI: 10.1016/j.smaim.2025.09.003

Narayani Prasad Kar , Junyi Lin , Ashkan HassankhaniRad , Wei Li , Alaa R. Aboushanab , Ying Li , Jingjing Sun

{"title":"Smart polymeric nanoparticles for targeted delivery and microenvironment-responsive therapy in pancreatic cancer","authors":"Narayani Prasad Kar , Junyi Lin , Ashkan HassankhaniRad , Wei Li , Alaa R. Aboushanab , Ying Li , Jingjing Sun","doi":"10.1016/j.smaim.2025.09.003","DOIUrl":"10.1016/j.smaim.2025.09.003","url":null,"abstract":"<div><div>Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies, characterized by aggressive biology, a dense fibrotic and immunosuppressive microenvironment, and profound resistance to standard therapies. Smart polymeric nanoparticles (SPNs), engineered to sense and respond to biological cues, present a transformative approach to overcome these barriers. This review highlights recent advances in SPNs tailored for PDAC, including systems designed to actively target tumor cells, cancer-associated fibroblasts (CAFs), and cancer stem cells (CSCs), thereby enhancing selective drug delivery and efficacy. SPNs also remodel the desmoplastic stroma or deliver matrix-modulating agents to improve tumor penetration. Furthermore, stimuli-responsive SPNs exploit the unique tumor microenvironment (TME) of PDAC, leveraging pH, hypoxia, or enzymatic triggers to achieve controlled, localized drug release. Beyond these strategies, SPNs have been developed to reprogram tumor immunity, modulate metabolic pathways, and enable precision gene therapy or combination treatments. Incorporating chronotherapy principles, future SPNs are capable of synchronizing drug release with circadian rhythms to maximize therapeutic windows while minimizing toxicity. Emerging concepts, such as integrating biosensors for real-time endogenous signal detection or applying AI-driven design to optimize SPN properties, underscore the future potential of these systems. Together, these multifaceted strategies position SPNs as a powerful platform to tackle the formidable challenges of PDAC and advance toward personalized cancer care.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 3","pages":"Pages 368-386"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The cell-loaded alginate microspheres in cell culture and disease treatment 载细胞海藻酸微球在细胞培养和疾病治疗中的应用

Smart Materials in Medicine Pub Date : 2025-12-01 Epub Date: 2025-11-07 DOI: 10.1016/j.smaim.2025.11.002

Meng-Yuan Wang , Han-Lin Tao , Jun Li , Xue-Yu Chen , Ya-Chao Gu , Ruizhi Tang , Xi-Qiu Liu

{"title":"The cell-loaded alginate microspheres in cell culture and disease treatment","authors":"Meng-Yuan Wang , Han-Lin Tao , Jun Li , Xue-Yu Chen , Ya-Chao Gu , Ruizhi Tang , Xi-Qiu Liu","doi":"10.1016/j.smaim.2025.11.002","DOIUrl":"10.1016/j.smaim.2025.11.002","url":null,"abstract":"<div><div>Due to the properties of biocompatibility, affordability, and high-throughput production capabilities, alginate-based biomaterials have been extensively studied in the biomedical field, which can be developed into scaffolds, hydrogels, and microspheres. To date, alginate microspheres encapsulating cells have been particularly attractive in cell culture, organoid construction, and tissue engineering applications because alginate microspheres can maintain exchange with external nutrients while providing immune isolation effects. This review summarizes various preparation methods for alginate microspheres loaded with cells, highlighting techniques such as extrusion, electrostatic microdroplet generation, coaxial airflow spraying, and microfluidics. Each method is evaluated for its advantages and disadvantages in terms of particle size, uniformity, and encapsulation efficiency. Furthermore, the review presents the recent development of cell-loaded alginate microspheres in the treatment of diabetes, bone defects, and liver failure, as well as their role in fabricating 3D tumor for drug screening. Finally, we also conclude by discussing the current limitations and future directions of alginate microspheres for improving therapeutic outcomes in various medical applications. Overall, alginate microspheres represent a significant advancement in the field of cell-based therapies and tissue engineering.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 3","pages":"Pages 387-405"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145620536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart nanomaterial-crosslinked hydrogels for biomedical applications 用于生物医学应用的智能纳米材料交联水凝胶

Smart Materials in Medicine Pub Date : 2025-12-01 Epub Date: 2025-11-07 DOI: 10.1016/j.smaim.2025.11.001

Xin Jin , Yin Li , Hang Ran, Zaihong Zhang, Peng Cheng, Yuxiang Wu

{"title":"Smart nanomaterial-crosslinked hydrogels for biomedical applications","authors":"Xin Jin , Yin Li , Hang Ran, Zaihong Zhang, Peng Cheng, Yuxiang Wu","doi":"10.1016/j.smaim.2025.11.001","DOIUrl":"10.1016/j.smaim.2025.11.001","url":null,"abstract":"<div><div>Hydrogels have advanced significantly in biomedical applications, yet their inherent hydrophilic matrices often hinder the efficient encapsulation and controlled release of hydrophobic drugs. Nanomaterial-crosslinked (NMC) hydrogels, in which nanomaterials (NMs) serve as crosslinkers rather than mere fillers, represent an innovative platform. NMC hydrogels synergistically integrate the tissue-mimetic and injectable properties of hydrogels with the versatile functionalities of NMs. This review systematically categorizes and discusses the diverse NM-polymer interactions, including irreversible covalent bonds, dynamic covalent bonds, and non-covalent interactions. These interactions that govern the formation and performance of NMC hydrogels and endow them with unique smart behaviors, such as stimuli-responsive phase transitions, programmable cargo release, self-healing capability, and suitability for 3D/4D bioprinting. Particular emphasis is placed on the design principles of NM-polymer interactions and their role in enhancing mechanical robustness, dynamic adaptability, and biomedical functionality. This review aims to inspire the development of more sophisticated and adaptable NMC hydrogel systems, thereby accelerating their translation into clinical practice.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 3","pages":"Pages 417-433"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanofiber membrane-foam composite sheet with dual pH-responsive functions of drug release and color change 具有药物释放和颜色变化双重ph响应功能的纳米纤维膜-泡沫复合片

Smart Materials in Medicine Pub Date : 2025-12-01 Epub Date: 2025-10-13 DOI: 10.1016/j.smaim.2025.10.001

Yinsong Wang , Xiangling Quan , Xiaoyu Duan , Dongliang Yang , Huijing Zhao , Kai Meng

{"title":"Nanofiber membrane-foam composite sheet with dual pH-responsive functions of drug release and color change","authors":"Yinsong Wang , Xiangling Quan , Xiaoyu Duan , Dongliang Yang , Huijing Zhao , Kai Meng","doi":"10.1016/j.smaim.2025.10.001","DOIUrl":"10.1016/j.smaim.2025.10.001","url":null,"abstract":"<div><div>Chronic wound repair remains challenging in skin regenerative medicine due to complex pathology and dynamic microenvironments. Traditional single-functional dressings fail to integrate exudate management, pH-responsive drug delivery, and inflammation monitoring, while empirical replacement disrupts microbial balance and impairs healing, making multifunctional smart dressings with high absorbency, pH-triggered release, and infection monitoring imperative. This study developed a dual pH-responsive, highly absorbent composite foam sheet using degradable wheat gluten (WG) as the primary matrix with auxiliary components-nanocellulose, glycerol, polyvinyl alcohol, and curcumin-based chromogenic capsules (Cur NC); an epigallocatechin gallate (EGCG)-loaded polyvinyl alcohol/sodium alginate (PVA/SA) electrospun nanofibrous membrane was integrated via chemical-physical methods. Its dual pH responsiveness involves pH-sensitive swelling of SA carboxyl groups and pH-dependent color changes of Cur NC. In vitro evaluations showed EGCG release of 74.22 % at pH 6.5 and 96.22 % at pH 8.5, with >99.99 % antibacterial activity against <em>Escherichia coli</em> and <em>Staphylococcus aureus</em>; the WG/Cur NC foam exhibited color transitions (yellow at pH 4–7, darkening with pH; red to reddish-brown at pH 7.4–9), enabling visual detection of infected wounds (pH > 7.4). The composite, crosslinked with CaCl<sub>2</sub> and negative pressure suction, had a dense interface with excellent peel strength, fracture strength, and liquid absorption. By synergizing pH-responsive drug release (nanofibers) and colorimetric monitoring (foam), this composite sheet addresses key challenges in chronic wound exudate management and infection warning, offering an innovative strategy to accelerate healing and reduce healthcare costs.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 3","pages":"Pages 334-346"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Programmable nucleic acid origami nanostructures for immunotherapy 用于免疫治疗的可编程核酸折纸纳米结构

Smart Materials in Medicine Pub Date : 2025-12-01 Epub Date: 2025-11-27 DOI: 10.1016/j.smaim.2025.11.004

Jia Jia , Xitong Liu , Chi Chen

{"title":"Programmable nucleic acid origami nanostructures for immunotherapy","authors":"Jia Jia , Xitong Liu , Chi Chen","doi":"10.1016/j.smaim.2025.11.004","DOIUrl":"10.1016/j.smaim.2025.11.004","url":null,"abstract":"<div><div>Immunotherapy has emerged as a pivotal strategy for restoring immune balance in diseased tissues, harnessing the immune system to eliminate malignant cells and suppress aberrant inflammatory responses at lesional sites while sparing healthy adjacent tissues. Programmable nucleic acid origami nanostructures can be precisely modified with diverse biomolecules at designated sites, making them superior delivery carriers for immune modulation. This review highlights the transformative therapeutic potential of nucleic acid origami nanostructures in the immunotherapy of cancer, inflammatory, and autoimmune diseases through regulation of both innate and adaptive immune pathways. Particular attention is given to their applications in antigen/adjuvant co-delivery for vaccine design, cytokine delivery, adoptive cell therapies, and combination immunotherapies. We further summarize current biomedical applications and clinical translation efforts, critically evaluating both opportunities and limitations. Overall, this review underscores the promise of nucleic acid origami nanostructures to redefine personalized immunotherapy and provides perspectives for future research directions.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 3","pages":"Pages 434-451"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoparticles in cancer therapy: Strategies to penetrate and modulate the tumor microenvironment – A review 纳米粒子在癌症治疗中的应用：穿透和调节肿瘤微环境的策略综述

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-08-05 DOI: 10.1016/j.smaim.2025.07.004

Chau Nguyen Minh Hoang , Son Hai Nguyen , Mai Thi Tran

{"title":"Nanoparticles in cancer therapy: Strategies to penetrate and modulate the tumor microenvironment – A review","authors":"Chau Nguyen Minh Hoang , Son Hai Nguyen , Mai Thi Tran","doi":"10.1016/j.smaim.2025.07.004","DOIUrl":"10.1016/j.smaim.2025.07.004","url":null,"abstract":"<div><div>Despite advances in conventional cancer treatments such as surgery, chemotherapy, and radiation, these approaches still face significant challenges, including systemic toxicity, limited tumor specificity, and therapy resistance. These limitations highlight the need for more effective, targeted therapeutic strategies. Nanotechnology has emerged as a promising solution in oncology, offering enhanced drug delivery, improved therapeutic efficacy, and reduced side effects. Among nanotechnology-based approaches, nanoparticle-based systems have gained clinical interest due to their biocompatibility, stability, and safety. Although various studies have investigated inorganic, organic, biological, and hybrid nanoparticles, existing reviews often focus solely on individual types, lacking direct comparisons of their performance regarding tumor penetration, controlled drug release, toxicity profiles, therapy resistance, and immune evasion capabilities. This review provides a comprehensive comparative analysis of these nanoparticle systems within the context of tumor microenvironment barriers. It also discusses critical challenges in clinical translation and highlights emerging hybrid platforms that integrate the advantages of multiple nanoparticle types, offering promising strategies for advancing cancer nanotherapy.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 270-284"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144865918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineered gold nanoparticle-based miRNA precision regulation for tumor diagnosis and synergistic therapy 基于工程化金纳米颗粒的miRNA精准调控在肿瘤诊断和协同治疗中的应用

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-23 DOI: 10.1016/j.smaim.2025.07.001

Li Chen, Haoyu Wang, Handan Zhang, Wenyun Mu, Xinran Shi, Xin Chen

{"title":"Engineered gold nanoparticle-based miRNA precision regulation for tumor diagnosis and synergistic therapy","authors":"Li Chen, Haoyu Wang, Handan Zhang, Wenyun Mu, Xinran Shi, Xin Chen","doi":"10.1016/j.smaim.2025.07.001","DOIUrl":"10.1016/j.smaim.2025.07.001","url":null,"abstract":"<div><div>Cancer remains a major global health challenge, with traditional therapies such as chemotherapy, radiotherapy, and surgery often limited by side effects, drug resistance, and incomplete tumor eradication. Recent advances in molecular biology have highlighted the dual role of microRNAs (miRNAs) in cancer, acting both as oncogenes and tumor suppressors, thereby offering new avenues for targeted therapy. Due to their unique physicochemical properties, including excellent biocompatibility, surface functionalization capabilities, and photothermal effects, gold nanoparticles (Au NPs) have emerged as a promising platform for miRNA delivery. However, a systematic understanding of how to effectively design Au NPs-miRNA systems for integrated tumor diagnosis and therapy, and their synergistic effects with photothermal therapy, chemotherapy, and immunotherapy to enhance therapeutic efficacy, remains lacking. In this review, we comprehensively summarized the advantages and challenges of the current Au NPs-miRNA system and discussed its recent advances in tumor diagnosis and therapy.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 225-239"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revolutionizing high altitude cerebral edema management: nanotechnology-enabled diagnostics and targeted drug delivery 革命性的高原脑水肿管理：纳米技术支持的诊断和靶向药物输送

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-06-20 DOI: 10.1016/j.smaim.2025.06.002

Yaqin Chen , Juan Pei , Jie Mou , Jin Fan , Lingting Fan , Yaolei Zhang , Xin Guo , Yonghong Fan , Hongyu Sun

{"title":"Revolutionizing high altitude cerebral edema management: nanotechnology-enabled diagnostics and targeted drug delivery","authors":"Yaqin Chen , Juan Pei , Jie Mou , Jin Fan , Lingting Fan , Yaolei Zhang , Xin Guo , Yonghong Fan , Hongyu Sun","doi":"10.1016/j.smaim.2025.06.002","DOIUrl":"10.1016/j.smaim.2025.06.002","url":null,"abstract":"<div><div>Due to the increasing commercial activities and adventure travels, millions of people visit high-altitude regions every year. A rapid increase in altitude results in high-altitude cerebral edema (HACE), an acute form of HAI characterized by altered mental status and ataxia, which necessitates immediate medical intervention to prevent patient mortality. Nevertheless, despite significant advancements in medical research and technology, the available diagnostic and therapeutic options for this disease remain limited. Currently, the accurate diagnosis of HACE relies predominantly on magnetic resonance imaging (MRI), while treatment strategies for this condition include passive descent to lower altitudes, oxygen supplementation, and pharmacological interventions. Unfortunately, these interventions are limited by their low efficacy, severe side effects, and poor availability under severe environmental conditions. Hence, alternative approaches are highly desired in the management of HACE. With the advancement of nanotechnology in theranostics, which enables more sensitive diagnosis, real-time monitoring, and targeted drug delivery, nanomedicine holds significant potential for the management of HACE. In this review, the pathological mechanism of HACE and the current theranostic options employed in clinics are described, and the potential applications and design strategy of nanomedicines for HACE management are discussed. We hope that this review can provide creative inspirations for the development of more precise, efficient, and low-side-effect theranostic alternatives for the management of HACE. This review will be of great interest to those working in materials science, nanotechnology, biomedical engineering, and translational medicine, and especially to those in military medicine and special medicine.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 152-170"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review on the applications of machine learning in biomaterials, biomechanics, and biomanufacturing for tissue engineering 综述了机器学习在组织工程生物材料、生物力学和生物制造中的应用

Smart Materials in Medicine Pub Date : 2025-08-01 Epub Date: 2025-06-27 DOI: 10.1016/j.smaim.2025.06.003

RenKai Fu , Zhenghong Chen , Hua Tian , Jiajie Hu , Fangxin Bu , Peng Zheng , Liang Chi , Lulu Xue , Qing Jiang , Lan Li , Liya Zhu

引用次数: 0