Sleep medicine最新文献

{"title":"A scoping review of sleep discrepancy methodology: What are we measuring and what does it mean?","authors":"Tom F. Walton ,&nbsp;Melissa J. Ree ,&nbsp;Simone N. Fueggle ,&nbsp;Romola S. Bucks","doi":"10.1016/j.sleep.2024.11.016","DOIUrl":"10.1016/j.sleep.2024.11.016","url":null,"abstract":"<div><h3>Study objectives</h3><div>To examine how past studies have conceptualised sleep discrepancy and identify and evaluate the methods used for its measurement and analysis.</div></div><div><h3>Method</h3><div>We searched MEDLINE, Embase, PsycINFO, CINAHL Plus, PubMed, Scopus, and Web of Science in April 2022 for studies comparing self-report and objective measures of sleep. Methodological information was extracted from relevant studies and included measures of self-report and objective sleep, sleep variables (e.g., total sleep time), derived discrepancy indices (e.g., difference scores), handling of repeated measurements, and methods of measure comparison (e.g., Bland-Altman analyses).</div></div><div><h3>Results</h3><div>Two hundred and forty-four relevant records were identified. Studies varied according to objective sleep measure; actigraphy algorithm, software, and rest interval; polysomnography setting and scoring criteria; sleep variables; self-report sleep measure; number of nights of objective recording; time frame of self-report measure; self-report sleep variable definition; sleep discrepancy derived index; presence and handling of repeated measurements; and statistical method for measure comparison.</div></div><div><h3>Conclusions</h3><div>Sleep discrepancy was predominantly conceived as discordance in sleep states or sleep time variables, and various forms of this discordance differed in their conceptual distance to sleep misperception. Furthermore, studies varied considerably in methodology with critical conceptual and practical implications that have received little attention to date. Substantive methodological issues were also identified relating to the use of derived indices for operationalising sleep discrepancy, defining objective sleep onset latency, calculating actigraphy rest intervals, measuring correlation and concordance, averaging sleep variables across nights, and defining sleep quality discrepancy. Solutions and recommendations for these issues are discussed.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 32-66"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The need for pediatric sleep education to enhance healthcare for children and adolescents: A global perspective from a survey of members of the international pediatric sleep association","authors":"Karen Spruyt ,&nbsp;Kate Chan ,&nbsp;Ridma Jayarathna ,&nbsp;Oliviero Bruni","doi":"10.1016/j.sleep.2024.12.005","DOIUrl":"10.1016/j.sleep.2024.12.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Sleep concerns have become increasingly common over the past few decades. This study outlines the perceived needs and gaps in pediatric sleep education, drawing insights from a diverse international cohort of pediatric sleep health professionals.</div></div><div><h3>Methods</h3><div>International Pediatric Sleep Association (IPSA) members were invited to complete an online survey examining a variety of topics related to pediatric sleep education developed by the education committee.</div></div><div><h3>Results</h3><div>There were 111 survey respondents, largely comprised of medical healthcare providers, representing 39 countries. The majority of respondents worked with children and adolescents aged 0–18 years and endorsed the importance of both comprehensive and developmentally appropriate screening for sleep issues in clinical practice, ranging from bedtime behaviors and daytime dysfunction to sleep-related breathing and movement disorder symptoms. Respondents also stressed the importance of including diverse topics in pediatric sleep education, including behavioral sleep issues and sleep in neurodevelopmental disorders, thus underscoring the need for comprehensive training programs. Participants advocated for improved access to screening tools and intervention protocols. There was an identified notable gap in formal sleep education during professional training. Potential barriers identified included time constraints and a lack of resources.</div><div>Preferences for training online and through professional organization websites underscored the importance of accessible learning platforms. Integrating online resources into education programs could enhance accessibility and engagement.</div></div><div><h3>Conclusion</h3><div>The demand for enhanced sleep education underscores the complexity and significance of pediatric sleep health and highlights an urgent need for tailored and accessible sleep education programs to address the multifaceted challenges in pediatric sleep. Addressing educational needs helps cultivate a skilled workforce to manage pediatric sleep disorders and promote healthy sleep practices. Teaching activities and collaboration play crucial roles in advancing the pediatric sleep community.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 314-318"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional brain iron mapping in obstructive sleep apnea adults","authors":"Bhaswati Roy ,&nbsp;Susana Vacas ,&nbsp;Daniel W. Kang ,&nbsp;Ravi S. Aysola ,&nbsp;Rajesh Kumar","doi":"10.1016/j.sleep.2024.12.022","DOIUrl":"10.1016/j.sleep.2024.12.022","url":null,"abstract":"<div><h3>Purpose</h3><div>Obstructive sleep apnea (OSA) subjects show significant white matter injury, including myelin changes in several brain areas, potentially from impaired glial cells, contributing to increased iron levels that escalate neurodegeneration, but brain iron loads are unclear. Our aim was to examine regional brain iron load, using T2∗-relaxometry, in OSA adults before and after continuous positive airway pressure (CPAP) treatment over controls.</div></div><div><h3>Methods</h3><div>We performed T2∗-weighted imaging using a 3.0-T MRI scanner on 35 OSA adults, who were followed after 3- and 9- mo CPAP treatment, and 67 controls. Using T2∗-weighted images, R2∗maps were calculated, normalized, and smoothed. The smoothed R2∗ maps, as well as average R2∗ values extracted from different brain regions were compared between OSA and controls using ANCOVA (covariates: age and sex) and paired t-tests in OSA adults.</div></div><div><h3>Results</h3><div>Multiple brain areas in OSA showed increased R2∗ values before CPAP, indicative of higher iron, over controls and included the amygdala, insula, hippocampus, cerebellum, medulla, and pons nearby areas. The R2∗ values continued to increase in multiple sites at 3-mo CPAP treatment in OSA, and those sites included the cerebellum, thalamus, and cingulate. However, after 9-mo CPAP usage, none of the brain regions showed increased R2∗ values in OSA over baseline.</div></div><div><h3>Conclusions</h3><div>OSA patients show increased iron content in multiple sites over controls, which progressively increased in several sites, even after 3-mo CPAP use, and started to clear after 9-mo. The findings suggest a means for intervention to lessen brain injury by interfering with iron accumulation in OSA.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 211-217"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between the vestibular system and the circadian timing system: A review","authors":"Tristan Martin ,&nbsp;Florane Pasquier ,&nbsp;Pierre Denise ,&nbsp;Damien Davenne ,&nbsp;Gaëlle Quarck","doi":"10.1016/j.sleep.2024.12.002","DOIUrl":"10.1016/j.sleep.2024.12.002","url":null,"abstract":"<div><div>This review attempts to analyze the relationship between the vestibular system and the circadian timing system. The activity of the biological clock allows an organism to optimally perform its tasks throughout the nychtemeron. To achieve this, the biological clock is subjected to exogenous factors that entrain it to a 24h period. While the most powerful synchronizer is the light-dark cycle produced by the Earth's rotation, research has led to the hypothesis of the vestibular system as a possible non-photic time cue used to entrain circadian rhythms. Demonstrated neuroanatomical pathways between vestibular nuclei and suprachiasmatic nuclei could transmit this message. Moreover, functional evidence in both humans and animals has shown that vestibular disruption or stimulation may lead to changes in circadian rhythms characteristics. Vestibular stimulations could be considered to act synergistically with other synchronizers, such as light, to ensure the entrainment of biological rhythms over the 24-h reference period.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 148-158"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in sleep-disordered breathing severity and post-stroke outcomes in the first year after stroke","authors":"Christopher J. Becker ,&nbsp;Lynda D. Lisabeth ,&nbsp;Guanghao Zhang ,&nbsp;Xu Shi ,&nbsp;Madeline Kwicklis ,&nbsp;Erin Case ,&nbsp;Ronald D. Chervin ,&nbsp;Devin L. Brown","doi":"10.1016/j.sleep.2024.12.010","DOIUrl":"10.1016/j.sleep.2024.12.010","url":null,"abstract":"<div><h3>Background</h3><div>Sleep-disordered breathing (SDB) is common among stroke survivors and is associated with worse functional, cognitive, and neurologic outcomes after stroke. Little is known about the association between changes in SDB and changes in these outcomes over time.</div></div><div><h3>Methods</h3><div>Ischemic stroke (IS) patients identified through the Brain Attack Surveillance in Corpus Christi project were offered SDB testing with a portable respiratory monitor (ApneaLink Plus) shortly after stroke, and at 3-, 6-, and 12-months post-stroke. SDB was quantified using the respiratory event index (REI; apneas plus hypopneas per hour of recording). At 3-, 6-, and 12-months post-stroke, functional outcomes, cognitive outcomes, and neurologic outcomes were measured. Linear mixed models were fitted to obtain random slopes reflecting individual changes in REI and each of outcome over time, adjusted for multiple covariates. Associations between the resulting individual slopes for REI and each outcome were then evaluated using linear regression models.</div></div><div><h3>Results</h3><div>Of 482 IS patients with at least one REI measurement, in fully adjusted models, faster reduction in REI was not associated with faster improvement in functional (β = −0.06; 95 % CI: −0.15, 0.03, p = 0.16), cognitive (β = −0.03; 95 % CI: −0.12, 0.06, p = 0.51), or neurologic outcomes (β = −0.04; 95 % CI: −0.13, 0.05, p = 0.41).</div></div><div><h3>Conclusions</h3><div>In this observational study of stroke survivors, there was no clear association between the rate of improvement in SDB and improvement in functional, cognitive, or neurologic outcomes. It remains to be seen whether treatment of SDB might lead to improved outcomes among stroke survivors.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 167-171"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between sleep opportunity, sleep problems, and social jetlag and toddlers' adiposity: A cross-sectional study","authors":"Ana Duarte ,&nbsp;Silvana Martins ,&nbsp;Cláudia Augusto ,&nbsp;Maria José Silva ,&nbsp;Luís Lopes ,&nbsp;Rute Santos ,&nbsp;Juliana Martins ,&nbsp;Rafaela Rosário","doi":"10.1016/j.sleep.2024.12.006","DOIUrl":"10.1016/j.sleep.2024.12.006","url":null,"abstract":"<div><div>This study aims to analyze the associations between sleep characteristics, including sleep opportunity, problems and social jetlag, and toddlers' adiposity. It is part of a larger research project involving 344 children (mean ± SD age of 23.6 ± 6.3 months). Children's length/height, weight and waist circumference were measured at childcare centers. Body Mass Index (BMI), weight-for-length/height, and waist-to-length/height were calculated and classified according to percentiles, serving as surrogates of adiposity. Sleep problems were evaluated through questionnaire. Sleep opportunity was reported by parents and defined as the difference between bedtime and wake-up time. Social jetlag was calculated based on sleep midpoints. Parental questionnaires provided sociodemographic characteristics. Total energy intake was determined from a two-day dietary record, and motor development was assessed using the Bayley-III scales. Generalized linear models were used in the analysis. We found that nighttime sleep opportunity on weekdays was inversely associated with BMI percentile (B = −5.57, 95 % CI -9.79 to −1.35), even with covariates included. Additionally, later bedtime on weekend days were associated with lower weight-for-length/height and waist-to-length/height (B = −4.16, 95 % CI -8.01 to −0.30, and B = −10.62, 95 % CI -15.38 to −5.87, respectively), even when adjusted for potential confounders. Later bedtime on weekdays was associated with lower waist-to-length/height (B = −8.85, 95 % CI -14.95 to −2.74). Social jetlag was associated with lower waist-to-length/height (B = −7.19, 95 % CI -13.47 to −0.90). Future research is needed to clarify these associations and to encourage lifestyle-based interventions aimed at optimizing sleep patterns within this age group.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 172-177"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of severity of obstructive sleep apnea by awake impulse oscillometry","authors":"Georg Schild ,&nbsp;Richard Schreiber ,&nbsp;Anke Lux ,&nbsp;Sabine Stegemann-Koniszewski ,&nbsp;Eva Lücke ,&nbsp;Jens Schreiber","doi":"10.1016/j.sleep.2024.12.016","DOIUrl":"10.1016/j.sleep.2024.12.016","url":null,"abstract":"<div><h3>Objective/background</h3><div>Obstructive sleep apnea (OSA) is a common disease, which poses a significant health threat. Initial diagnostics with polygraphy or polysomnography are time consuming and expensive. Therefore, there is an unmet medical need for simplification, especially to exclude healthy patients from elaborate and unnecessary diagnostics. Impulse oscillometry (IOS) is a simple, cheap and noninvasive tool to asses upper airway resistance, which is increased in patients with OSA. The objective was to examine the relationship between IOS parameters and polysomnography in order to evaluate the applicability of IOS as a supplementing tool in OSA diagnostics.</div></div><div><h3>Patients/methods</h3><div>We performed a prospective, cross-sectional, observational study across 107 participants. Pulmonary function tests with IOS, bodyplethysmography and overnight polysomnography were performed. We computed direct and partial correlations between IOS- and PSG-results. ROC analysis was performed to evaluate the most impactful predictive IOS parameter for diagnosing OSA.</div></div><div><h3>Results</h3><div>In ROC analysis the predicted probability of resistance at 5Hz (R5%) combined with age showed the highest AUC of 0.919, while R5 at 0.4325kPa/(l/s) provided the optimal cut-off. Correlations between IOS parameters and OSA severity as well as the duration and severity of oxygen desaturation were observed. However, they could not be reproduced as partial correlations after eliminating the BMI as confounding variable.</div></div><div><h3>Conclusion</h3><div>Our results cannot indicate the usefulness of IOS in OSA diagnostics. The lack of BMI-independent partial correlations between IOS- and PSG-results suggest a correlation without causality fallacy between IOS- and PSG-results. Therefore, the initial impression of good test quality for IOS might be invalid.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 218-221"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of transcranial alternating current stimulation on EEG spectral power during subsequent sleep: A randomized crossover study","authors":"Yuan Shi ,&nbsp;Xin Tian ,&nbsp;Taomei Li ,&nbsp;Yuexia Hu ,&nbsp;Yuqing Xie ,&nbsp;Huixian Li ,&nbsp;Yun Li ,&nbsp;Ning Jiang ,&nbsp;Xiangdong Tang ,&nbsp;Yanyan Wang","doi":"10.1016/j.sleep.2024.12.011","DOIUrl":"10.1016/j.sleep.2024.12.011","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the instant impact of transcranial alternating current stimulation (tACS) on sleep brain oscillations.</div></div><div><h3>Methods</h3><div>Thirty-six healthy subjects were randomly assigned to receive tACS and sham stimulation in a crossover design separated by a one-week washout period. After stimulation, a 2-h nap polysomnography (PSG) was performed to obtain Electroencephalogram (EEG) data and objective sleep variables, and self-reported subjective sleep parameters were collected at the end of the nap. EEG spectral analyses were conducted on the EEG data to obtain the absolute and relative power for each sleep stage during the nap. The associations between power values and objective and subjective measurements were analyzed using Spearman or Pearson correlation coefficients.</div></div><div><h3>Results</h3><div>The tACS group presented higher power in slow wave activity (SWA) and delta frequency bands and lower alpha, sigma and beta power values compared to the sham group during the N2 and N3 sleep stages. SWA and delta power were positively associated with sleep duration and sleep efficiency relevant parameters; while alpha, sigma and beta power were positively associated with prolonged sleep latency and wakefulness related variables. PSG, self-reported and sleep diary measured objective and subjective sleep parameters were comparable between the tACS and the sham groups.</div></div><div><h3>Conclusion</h3><div>Our results support that tACS could promote sleep depth in microstructure of sleep EEG, manifesting as an increase in EEG spectral power in low frequency bands and a decrease in high frequency bands.</div><div>The registration number of this study is ChiCTR2200063729.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 185-193"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconfigurations of dynamic functional network connectivity after 1HZ repetitive transcranial magnetic stimulation in insomnia disorder","authors":"Wuyuan Xin ,&nbsp;Ting Xue ,&nbsp;Yongxin Cheng ,&nbsp;Fang Dong ,&nbsp;Juan Wang ,&nbsp;Yuxin Ma ,&nbsp;Shan Zhang ,&nbsp;Fan Zhang ,&nbsp;Jingjing Ding ,&nbsp;Daining Song ,&nbsp;Junxuan Wang ,&nbsp;Yifei Zhu ,&nbsp;Haitao Ju ,&nbsp;Kai Yuan ,&nbsp;Xiaona Sheng ,&nbsp;Dahua Yu","doi":"10.1016/j.sleep.2024.12.025","DOIUrl":"10.1016/j.sleep.2024.12.025","url":null,"abstract":"<div><h3>Aims</h3><div>The objective of the current study was to investigate the dynamic functional connectivity among large-scale brain networks in patients with insomnia, and to assess the efficacy of repetitive transcranial magnetic stimulation (rTMS) treatment in these individuals.</div></div><div><h3>Methods</h3><div>Resting-state functional magnetic resonance imaging (rs-fMRI) data from 62 insomnia patients and 69 healthy controls were used to compare differences in dynamic functional connectivity between the two groups. A total of 26 insomnia patients underwent rTMS for four weeks. Changes in dynamic functional network connectivity was observed in insomnia patients following treatment. Additionally, the relationship between clinical symptoms and insomnia was analyzed using topological and correlation analyses.</div></div><div><h3>Results</h3><div>Our findings demonstrated that insomnia patients exhibited a significantly lower fraction rate of negative connectivity between the dorsal default mode network (dDMN) and the visual network (VN) compared to healthy controls, while showing strong positive connectivity within the VN and the auditory network (AUN). It may be attributed to the restoration of normal dynamic functional connectivity between the dDMN and VN in insomnia patients following rTMS. Furthermore, the dynamic functional connectivity between the dDMN and VN was found to predict sleep quality and treatment outcome in insomnia patients.</div></div><div><h3>Conclusion</h3><div>Abnormal dynamic functional network connectivity between the dDMN and VN is a hallmark of insomnia, and may serve as a biomarker to assess the effects of rTMS treatment in insomnia patients.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 239-247"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High sleep reactivity in shift workers is associated with increased sleep disturbance, mood problems, and reduced quality of life","authors":"Hanseul Kim ,&nbsp;Kyung Hwa Lee ,&nbsp;Jiyoon Shin ,&nbsp;Won Woo Seo ,&nbsp;Jeong Eun Jeon ,&nbsp;Ha Young Lee ,&nbsp;Jin Hyeok You ,&nbsp;Sun-Young Kim ,&nbsp;Seog Ju Kim ,&nbsp;Yu Jin Lee","doi":"10.1016/j.sleep.2024.12.027","DOIUrl":"10.1016/j.sleep.2024.12.027","url":null,"abstract":"<div><h3>Introduction</h3><div>Shift work disrupts circadian rhythms, causing sleep and mood problems. Sleep reactivity—the sensitivity of sleep to stress—may affect how shift workers cope with these disruptions. This study investigated the relationship between sleep reactivity and shift work, exploring associations between sleep reactivity and sleep disturbance, mood symptoms, and quality of life in shift workers.</div></div><div><h3>Methods</h3><div>In a cross-sectional design, 132 participants (79 shift workers and 53 controls) were assessed using the Ford Insomnia Response to Stress Test (FIRST), Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and World Health Organization Quality of Life (WHOQOL). We compared the self-reported measurements between shift workers and controls. Two-way ANOVA was performed to explore the interaction effects between shift work and sleep reactivity on sleep, mood parameters, and quality of life. Multiple linear regression analysis was conducted to identify factors associated with sleep, mood, and quality of life among shift workers.</div></div><div><h3>Results</h3><div>Shift workers scored higher on ISI and BDI compared to controls. Two-way ANOVA revealed an interaction effect between shift work and sleep reactivity on WHOQOL. Regression analysis indicated that high sleep reactivity was associated with higher ISI, BDI, BAI, and lower WHOQOL among shift workers.</div></div><div><h3>Conclusion</h3><div>Sleep reactivity significantly affected shift worker’s quality of life. Our findings indicate that high sleep reactivity in shift workers was associated with increased sleep disturbance, mood problems, and decreased quality of life, implying that sleep reactivity may predict shift work tolerance.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"126 ","pages":"Pages 275-281"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}