Skeletal Radiology最新文献

Radiological assessment of extremity bone involvement in Erdheim-Chester disease: a systematic review of case reports. Erdheim-Chester病四肢骨受累的放射学评估：对病例报告的系统回顾。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-09 DOI: 10.1007/s00256-024-04835-9

Arash Azhideh, Alireza Pouramini, Sara Haseli, Elahe Abbaspour, Gita Karande, Fatemeh Kafi, Majid Chalian

{"title":"Radiological assessment of extremity bone involvement in Erdheim-Chester disease: a systematic review of case reports.","authors":"Arash Azhideh, Alireza Pouramini, Sara Haseli, Elahe Abbaspour, Gita Karande, Fatemeh Kafi, Majid Chalian","doi":"10.1007/s00256-024-04835-9","DOIUrl":"10.1007/s00256-024-04835-9","url":null,"abstract":"Objective: To describe the clinical presentations and radiological manifestations of Erdheim-Chester disease (ECD) in the extremities, with particular emphasis on radiologic findings, as radiographs are typically the initial imaging modality used in clinical practice.Methods: Following the PRISMA guidelines, a comprehensive systematic search was performed across Scopus, PubMed, Web of Science, and Embase databases, covering case reports from inception until August 1, 2024. Included were studies with pathologically confirmed ECD (CD68 positive and CD1a negative) that were evaluated with at least one imaging modality and provided detailed descriptions of radiological findings.Results: Out of 401 identified articles, 20 articles comprising 20 histologically confirmed cases of ECD met the inclusion criteria following screening and full-text review. Pathological reports were assessed for the presence of lipid-laden cells and Touton giant cells, which were identified in 84.2% and 75% of cases, respectively. Upper extremities were affected in 65% of cases and lower extremities in all cases. Symmetric involvement was observed in 84.6% of upper extremity cases and 84.2% of lower extremity cases. Radiological findings were categorized as pure sclerosis (53.3%) and cortical thickening (42.8%) identified as the most common findings. Clinical manifestations were assessed, with pain and swelling in the extremities being the most common symptoms, occurring in 70% of cases.Conclusion: The hallmark of ECD is bilateral, symmetric diaphyseal and/or metaphyseal osteosclerosis in the long tubular bones of the lower extremities. Epiphyseal sparing is observed in more than half of the patients.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1441-1455"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Test Yourself Question: Pain in the left hip following previous surgery in a 60-year-old male. 自我测试问题：一名60岁男性，既往手术后左髋关节疼痛。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-03 DOI: 10.1007/s00256-024-04840-y

K Howard, C Han, P Balogh, V Kurisunkal, R Botchu

引用次数: 0

Xanthogranulomatous osteomyelitis: multimodality imaging of a rare case involving tibial diaphysis with review of literature. 黄色肉芽肿性骨髓炎：一例罕见病例累及胫骨骨干的多模态影像分析并文献复习。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-23 DOI: 10.1007/s00256-024-04851-9

Shilpa Mohanan, Suryansh Bajaj, Evgeniya Pasternak, Rodolfo Henrich Lobo, Gitanjali Bajaj

引用次数: 0

Soft tissue mass resembling myxochondroid metaplasia in Achilles tendon. 类似于跟腱粘液软骨样化生的软组织肿块。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-02 DOI: 10.1007/s00256-024-04836-8

F Bilge Ergen, Rana Naous, Sophie Darwiche, Jonathan Daniel Hughes, Lucas Da Gama Labo, Cynthia Britton

引用次数: 0

Deep learning algorithm enables automated Cobb angle measurements with high accuracy. 深度学习算法可实现高精度的自动科布角测量。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-17 DOI: 10.1007/s00256-024-04853-7

Daichi Hayashi, Nor-Eddine Regnard, Jeanne Ventre, Vincent Marty, Lauryane Clovis, Ludovic Lim, Nicolas Nitche, Zekun Zhang, Antoine Tournier, Alexis Ducarouge, Andrew J Kompel, Chadi Tannoury, Ali Guermazi

{"title":"Deep learning algorithm enables automated Cobb angle measurements with high accuracy.","authors":"Daichi Hayashi, Nor-Eddine Regnard, Jeanne Ventre, Vincent Marty, Lauryane Clovis, Ludovic Lim, Nicolas Nitche, Zekun Zhang, Antoine Tournier, Alexis Ducarouge, Andrew J Kompel, Chadi Tannoury, Ali Guermazi","doi":"10.1007/s00256-024-04853-7","DOIUrl":"10.1007/s00256-024-04853-7","url":null,"abstract":"Objective: To determine the accuracy of automatic Cobb angle measurements by deep learning (DL) on full spine radiographs.Materials and methods: Full spine radiographs of patients aged > 2 years were screened using the radiology reports to identify radiographs for performing Cobb angle measurements. Two senior musculoskeletal radiologists and one senior orthopedic surgeon independently annotated Cobb angles exceeding 7° indicating the angle location as either proximal thoracic (apices between T3 and T5), main thoracic (apices between T6 and T11), or thoraco-lumbar (apices between T12 and L4). If at least two readers agreed on the number of angles, location of the angles, and difference between comparable angles was < 8°, then the ground truth was defined as the mean of their measurements. Otherwise, the radiographs were reviewed by the three annotators in consensus. The DL software (BoneMetrics, Gleamer) was evaluated against the manual annotation in terms of mean absolute error (MAE).Results: A total of 345 patients were included in the study (age 33 ± 24 years, 221 women): 179 pediatric patients (< 22 years old) and 166 adult patients (22 to 85 years old). Fifty-three cases were reviewed in consensus. The MAE of the DL algorithm for the main curvature was 2.6° (95% CI [2.0; 3.3]). For the subgroup of pediatric patients, the MAE was 1.9° (95% CI [1.6; 2.2]) versus 3.3° (95% CI [2.2; 4.8]) for adults.Conclusion: The DL algorithm predicted the Cobb angle of scoliotic patients with high accuracy.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1469-1478"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Test yourself answer: a 67-year-old male with worsening right shoulder pain and restricted range of motion. 自测答案：67岁男性右肩疼痛加重，活动受限。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2025-01-23 DOI: 10.1007/s00256-025-04869-7

Kevin Quinlan, Scott Evans, Petra Balogh, Mahmoud Etaiwi, Rajesh Botchu

引用次数: 0

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-05 DOI: 10.1007/s00256-024-04852-8

Bukola A Olarewaju, Erin R Alexander, Monica M Crowe, Kristina Dandurand, David Melville, Fadi Shamoun, Mayowa A Osundiji

{"title":"COL9A1-related disorder with pectus carinatum, without epiphyseal dysplasia: case report and review of literature.","authors":"Bukola A Olarewaju, Erin R Alexander, Monica M Crowe, Kristina Dandurand, David Melville, Fadi Shamoun, Mayowa A Osundiji","doi":"10.1007/s00256-024-04852-8","DOIUrl":"10.1007/s00256-024-04852-8","url":null,"abstract":"COL9A1 encodes the alpha-1 chain of type IX collagen heterotrimer, which is a vital component of collagen fibrils in hyaline cartilage. There are preliminary lines of evidence suggesting that COL9A1 mutations may be associated with autosomal dominant multiple epiphyseal dysplasia (MED), a disorder affecting the epiphysis of long bones. With only 2 reported cases (both from the same family) of MED in autosomal dominant COL9A1-related disorders (MIM 614135) in the clinical scientific literature hitherto, the phenotype is poorly understood at present. Here, we report the clinical and imaging findings associated with a novel COL9A1 mutation in comparison to the previously reported cases. We studied a 22-year-old male, who presented with a chronic history of leg pain and laxity of the knee joint, in the context of a history of pectus carinatum requiring a chest brace, and tall stature (height = 186.9 cm) with bilateral piezogenic pedal papules. Gene panel testing and a radiographic skeletal survey were subsequently performed. Gene panel test showed a heterozygous pathogenic variant in the COL9A1 that is denoted as c.188del (p.Phe63Serfs*3) and is predicted to result in a loss-of-function. The patient's long bones all appeared slender on a radiograph, without apparent epiphyseal dysplasia. Our findings suggest that the phenotypic spectrum of COL9A1-related disorders may potentially include other skeletal anomalies (such as pectus carinatum and slender appearance of long bones) aside from epiphyseal dysplasia.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1537-1541"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Small but mighty" - A radiologists' primer for ultrasound imaging of the smaller peripheral nerves. “小而有力”——放射科医生的小周围神经超声成像入门。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-03 DOI: 10.1007/s00256-024-04844-8

Aakanksha Agarwal, Abhishek Chandra, Kapil Shirodkar, Ankit Shah, Timothy E Murray, Karthikeyan P Iyengar, Mahesh Prakash, Rajesh Botchu

引用次数: 0

Characteristics of femur morphology and proximal femur bone mineral density in Japanese females with bisphosphonate-related atypical femur fractures. 日本女性双膦酸盐相关非典型股骨骨折患者股骨形态和股骨近端骨密度特征

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-22 DOI: 10.1007/s00256-024-04857-3

Koun Yamauchi, Chisato Kato, Takayuki Kato

{"title":"Characteristics of femur morphology and proximal femur bone mineral density in Japanese females with bisphosphonate-related atypical femur fractures.","authors":"Koun Yamauchi, Chisato Kato, Takayuki Kato","doi":"10.1007/s00256-024-04857-3","DOIUrl":"10.1007/s00256-024-04857-3","url":null,"abstract":"Objective: To determine which parameters, including femur morphology, proximal femur bone mineral density, or patient characteristics, are associated with bisphosphonate-related atypical femur fractures (AFFs) and to investigate the relationships between AFF location and these parameters.Materials and methods: Sixteen females with a history of bisphosphonate use who presented with AFFs and 38 females without AFFs, even those with long-term bisphosphonate use of > 5 years, were compared. Patient characteristics; physique, gait ability, and history of pain and medication, were recorded. In terms of femur morphology, the mechanical lateral distal femoral articular angle (mLDFA), femoral bowing angle, femoral neck - shaft angle, and ratio of the femoral lateral cortex:neck width were measured via anteroposterior femur radiographs. Bone mineral density values of the femur neck, trochanter, inter, and Ward's triangle were used. Logistic regression analysis was conducted to determine independent factors for the AFF. In the 16 AFF patients, AFF locations were divided into 1: subtrochanteric, 2: proximal, 3: middle, and 4: distal femur diaphysis. The Spearman correlation coefficients (rs) between the AFF locations and the parameters were calculated.Results: Logistic regression analysis revealed that the mLDFA and Ward's triangle values were significantly independently associated with AFF patients (odds ratios = 1.4 and 0.0, respectively). A more distal AFF location was significantly correlated with a shorter body height and greater BMI (rs = -0.69 and 0.67, respectively).Conclusion: An evaluation combining the mLDFA and Ward's triangle value could be used to predict the risk of bisphosphonate-related AFFs. Body height or BMI may be helpful for predicting AFF location.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1503-1510"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance of PSMA-PET/CT as verified by bone biopsy for diagnosing osseous metastases of prostate cancer. 骨活检证实PSMA-PET/CT诊断前列腺癌骨转移的表现。

IF 1.9 3区医学

Skeletal Radiology Pub Date : 2025-07-01 Epub Date: 2024-12-20 DOI: 10.1007/s00256-024-04855-5

William C Ou, Jack W Jennings, Benjamin E Northrup, Gino M Dettorre, Winston L Winkler, Resten Imaoka, Theodore L Vander Velde, Barry A Siegel

{"title":"Performance of PSMA-PET/CT as verified by bone biopsy for diagnosing osseous metastases of prostate cancer.","authors":"William C Ou, Jack W Jennings, Benjamin E Northrup, Gino M Dettorre, Winston L Winkler, Resten Imaoka, Theodore L Vander Velde, Barry A Siegel","doi":"10.1007/s00256-024-04855-5","DOIUrl":"10.1007/s00256-024-04855-5","url":null,"abstract":"Objective: Prostate-specific membrane antigen (PSMA)-PET/CT has shown considerable promise in the evaluation of prostate cancer bone metastases; however, data utilizing a histopathologic reference standard in this setting are limited. We therefore sought to evaluate the diagnostic performance of PSMA-PET/CT using a consistent histopathologic gold standard in the form of bone biopsy.Materials and methods: In this single-center, retrospective study, we identified 80 patients with prostate cancer who underwent CT-guided bone biopsy of a tracer-avid osseous lesion on PSMA-PET/CT performed with 18F-piflufolastat. Concordance between PET/CT and histopathology and the positive predictive value of PSMA-PET/CT were determined. Factors predictive of positive biopsies were also evaluated.Results: PSMA-PET/CT and bone biopsy results were concordant in 55/80 patients (69%), and the positive predictive value of PSMA-PET/CT for osseous metastasis of prostate cancer was 66% (53/80). Positive predictive values for spine, pelvis, and rib biopsies were 82% (23/28), 72% (18/25), and 26% (5/19), respectively. Peak SUV and its ratio to liver mean SUV were significantly higher in biopsy-positive lesions compared to biopsy-negative lesions. A threshold peak SUV to liver mean SUV ratio of 1.7 had a sensitivity of 61% and a specificity of 92% for a histopathologic diagnosis of metastatic prostate cancer.Conclusion: PSMA-PET/CT has a moderately high histopathologic concordance and positive predictive value for the diagnosis of osseous metastatic disease in prostate cancer. Peak SUV is useful for distinguishing biopsy-positive from biopsy-negative lesions. In keeping with prior investigations, a majority of biopsied rib lesions were negative for metastatic prostate cancer.","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1479-1489"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0