Skeletal Radiology最新文献

{"title":"Global insights on diversity, equity, and inclusion-perspectives and experiences from musculoskeletal radiologists of the International Skeletal Society DEI Committee.","authors":"Avneesh Chhabra, Erin F Alaia, Matthew D Bucknor, Jung-Ah Choi, Bruce B Forster, Soterios Gyftopoulos, Daichi Hayashi, Amanda Isaac, Khaled Matrawy, Kevin C McGill, Kambiz Motamedi, Mahesh Prakash, Aline Serfaty, Stacy E Smith, Kathryn J Stevens, Miriam A Bredella","doi":"10.1007/s00256-025-04926-1","DOIUrl":"10.1007/s00256-025-04926-1","url":null,"abstract":"<p><p>Diversity, equity, and inclusion (DEI) is important for delivering high-quality, culturally competent care and ensuring equal access to resources and opportunities in healthcare. However, the implementation of DEI has been met with unique challenges and successes across the globe. The International Skeletal Society (ISS), a multidisciplinary musculoskeletal society, made a conscious effort to promote DEI. This article discusses advantages and controversies of DEI approaches, DEI initiatives implemented by the ISS, and experiences of the ISS DEI committee members from their respective continents. The ISS DEI committee implemented educational webinars with expert panel discussions, revising membership criteria and policies for enhancing inclusiveness, advising on programing and speakers for the annual meeting, and fostering mentorship. From a global perspective, in North America, DEI has improved health outcomes and patient care, but anti-DEI legislation has posed significant challenges. Europe relies on international recruitment but faces challenges in staff retention. South America's cultural diversity necessitates culturally sensitive approaches, but discussions about DEI are scarce, and gender inequalities persist in leadership. In Africa, DEI principles are underdeveloped, with limited engagement among stakeholders. In Asia, DEI is emerging, with more women being appointed to faculty positions and leadership roles in academic societies. The implementation of meaningful DEI initiatives requires long-term institutional buy-in and the global participation and commitment of employees and institutional leaders at all levels.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1811-1820"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Test yourself answer: an elderly man presenting with features of cauda equina.","authors":"Muhammad Riaz, Hasaam Uldin, Scott Evans, Petra Balogh, Rajesh Botchu","doi":"10.1007/s00256-025-04887-5","DOIUrl":"10.1007/s00256-025-04887-5","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1993-1996"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective validation of the Birmingham atypical cartilage tumor imaging protocol (BACTIP) in a single, United States tertiary care center.","authors":"Sonja Opper, Samuel Saucedo, Lisa Ercolano, Lulu He","doi":"10.1007/s00256-025-04900-x","DOIUrl":"10.1007/s00256-025-04900-x","url":null,"abstract":"<p><strong>Background: </strong>Central cartilage tumors are common incidental lesions around knee and shoulder joints. Differentiation of low-grade chondroid lesions, such as enchondroma from atypical cartilaginous tumor (ACT) is often difficult on imaging given pathologic and radiologic similarities. The Birmingham atypical cartilage tumor imaging protocol (BACTIP) provides a guide to initial assessment and imaging follow-up for incidental indeterminate central cartilage tumors.</p><p><strong>Objective: </strong>This study retrospectively evaluates BACTIP in a United States tertiary care center.</p><p><strong>Methods: </strong>Indeterminate central cartilage tumors in the proximal humerus, distal femur, and proximal tibia of adults were identified by a keyword search in the health network picture archiving and communications systems (PACS). These were categorized into one of seven BACTIP categories based on criteria including size and degree of endosteal scalloping.</p><p><strong>Results: </strong>There were 292 cases that met the inclusion criteria. The final diagnosis of enchondroma was 100% for lesion types IA and IB, 66% for IC, and 50% for IIB; ACT was 33% for IC and 50% for IIB. Of the type IIC lesions, 43% were diagnosed as intermediate or high-grade chondrosarcoma. Pathology diagnosis was dedifferentiated chondrosarcoma in 75% of type III lesions. Chart review and follow-up imaging revealed no delay of diagnosis. The malignant transformation rate in this study was 0.3%.</p><p><strong>Conclusion: </strong>There were no cases where the application of BACTIP would have led to a delayed diagnosis. The BACTIP would serve as a conservative and appropriate imaging follow-up guideline for patients with central cartilage tumors around the shoulder and knee joint.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1927-1937"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in photon-counting detector computed tomography-derived scaphotrapeziotrapezoid joint morphometrics.","authors":"Taylor P Trentadue, Andrew Thoreson, Cesar Lopez, Ryan E Breighner, Shuai Leng, Sanjeev Kakar, Marco Rizzo, Kristin D Zhao","doi":"10.1007/s00256-024-04863-5","DOIUrl":"10.1007/s00256-024-04863-5","url":null,"abstract":"<p><strong>Objective: </strong>The scaphotrapeziotrapezoid (STT) joint transmits load between the wrist and thumb. Despite its clinical importance, it has received less diagnostic attention than adjacent wrist and thumb joints. CT-derived three-dimensional models offer the ability to improve measurement of articular space by evaluating subchondral articular surfaces, which can be quantified using articular morphometrics. The objectives of this study were to investigate whether articular surface areas, interosseous proximities, and carpal bone positions differ between sexes.</p><p><strong>Materials and methods: </strong>Thirty participants (50% female, median age 27.0 years) were prospectively recruited to a cohort study of normative wrist imaging and biomechanics. Carpal bones were meshed from CT-based segmentations using a marching cubes algorithm. Rigid body kinematic parameters of individual bones were calculated. Carpal bone postures were defined using projection angles between bone centroids. Articular surface areas and interosseous proximity distributions between adjacent bones were calculated. Morphometrics were compared between sexes using Wilcoxon rank sum or two-tailed Kolmogorov-Smirnov tests as appropriate.</p><p><strong>Results: </strong>Median articular surface area was significantly smaller in females than in males at the trapeziotrapezoid but not scaphotrapezium or scaphotrapezoid joints. Interosseous proximity distributions were closer in females at all joints (scaphotrapezium, 1.19 versus 1.42 mm; scaphotrapezoid, 1.15 versus 1.43 mm; trapeziotrapezoid, 0.45 versus 0.65 mm). Distal bones were more dorsally translated in females.</p><p><strong>Conclusion: </strong>This study quantifies sex-stratified morphological variations at the STT joint. Interosseous proximity distributions may guide interpretation of imaging-derived STT joint space and can serve as reference ranges for studies of STT arthrokinematics.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1851-1861"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifaceted imaging strategies for clinical trials of knee osteoarthritis-a tightly interlinked value and precision chain.","authors":"Felix Eckstein, Ali Mobasheri, Mikael P Boesen","doi":"10.1007/s00256-025-04919-0","DOIUrl":"10.1007/s00256-025-04919-0","url":null,"abstract":"<p><p>Osteoarthritis is a debilitating, whole-organ disease that involves all osteoarticular tissues. No effective treatments have yet been approved by the regulatory agencies for modifying the natural history of this disease and its structural progression. In this whitepaper, we will summarize concepts of \"multi-faceted\" (multi-contrast) magnetic resonance imaging (MRI), with a focus on its application in osteoarthritis clinical trials. The process described here encompasses a tightly interlinked value and precision chain, where all elements must be aligned seamlessly for the trial to succeed. The procedure should begin with careful patient characterization and selection, potentially aided by (multifaceted) imaging, so that the disease (sub-) types in these potential participant will match the mechanism of action (MOA) of the medical investigational product (i.e., the drug studied). This should be followed by a comprehensive yet efficient MRI acquisition protocol, employing sequences with various contrasts that permit the characterization of imaging-based joint pathologies and evaluation of the drug's MOA. Suitable image analysis tools must be employed, ideally adhering to regulatory compliance standards. Multiple validated endpoints can be derived from the various (multifaceted) contrasts, to be potentially combined to multi-component or composite endpoints, based on stringent a-priori rules. In conclusion, a robust value and precision chain needs to be fully functional for a disease-modifying osteoarthritis trial to be successful. Participant selection must be mindful of the drug's MOA, and a well-aligned and custom-tailored \"multifaceted\" image acquisition protocol, suitable image analysis tools, and meaningful endpoints should be in place, which should match the specific image contrasts.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1789-1802"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between articular calcium crystal deposition and knee osteoarthritis, joint pain and inflammation: a cross-sectional study.","authors":"Camilla Toft Nielsen, Marius Henriksen, Cecilie Laubjerg Daugaard, Janus Uhd Nybing, Philip Hansen, Felix Müller, Henning Bliddal, Mikael Boesen, Henrik Gudbergsen","doi":"10.1007/s00256-025-04904-7","DOIUrl":"10.1007/s00256-025-04904-7","url":null,"abstract":"<p><strong>Objective: </strong>To explore in a cross-sectional fashion if overweight individuals with knee osteoarthritis (OA) and intraarticular calcium crystal (CaC) deposits experience more knee joint inflammation and knee pain compared with individuals without CaC deposits.</p><p><strong>Subjects and methods: </strong>We used pre-randomization imaging data from an RCT, the LOSE-IT trial. Participants with knee OA (clinical diagnosis of knee OA and KLG 1-3) had CT and 3 T MRI of the index knee. CaCs were assessed on CT using the Boston University Calcium Knee Score (BUCKS). The pain subscale of the Knee Injury and Osteoarthritis Outcome Score (KOOS) was used to assess knee pain and to estimate joint inflammation we used static and dynamic contrast-enhanced (DCE) MRI. An independent sample t-test was used to test for a significant difference in KOOS-pain and Analysis of Covariance (ANCOVA) models to test for differences in the static and DCE-MRI variables between the two groups.</p><p><strong>Results: </strong>Of the 158 participants with KOOS-pain available, 19 (12%) had CaC deposits, and of the 115 participants with MRI available, 13 (11.3%) had CaC deposits. We did not find a significant difference in mean KOOS-pain between the two groups; the mean difference was - 2.2 points (95%CI, - 10.86, 6.45). None of the MRI variables were associated with the presence of CaC deposits. Between-group differences were small for all MRI variables, with standardized mean differences ranging from small to medium (0.31-0.56).</p><p><strong>Conclusion: </strong>In individuals with knee OA, we did not find an association between intraarticular CaC deposits and an increase in knee joint inflammation or knee pain.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1939-1947"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between medial knee joint bone morphology and popliteal cyst: a retrospective MRI-based analysis.","authors":"Erdi Imre, Bilgin Bozgeyik","doi":"10.1007/s00256-025-04890-w","DOIUrl":"10.1007/s00256-025-04890-w","url":null,"abstract":"<p><strong>Objective: </strong>Baker's cyst, or popliteal cyst, is a common knee condition associated with osteoarthritis and rheumatoid arthritis. While previous studies have explored the cyst's relationship with soft tissue abnormalities, the connection between popliteal cysts and medial knee bone morphology remains unclear. This study aims to assess the association between anatomical bone structures of the medial knee joint and popliteal cyst presence using magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 100 patients who underwent MRI for knee pain between June and December 2021. Group 1 (n = 50) consisted of patients with Baker's cysts, and group 2 (n = 50) included those without cysts. MRI measurements included medial condyle width, condyle length, distal and posterior articular diameters, medial tibial plateau depth, and tibial slope. Cyst dimensions and volume were measured. Statistical analyses, including Pearson correlation and chi-square tests, were performed, with significance set at p < 0.05.</p><p><strong>Results: </strong>No significant differences in medial knee bone morphology were found between groups (p > 0.05). However, popliteal cyst size was positively correlated with age (p = 0.016, r = 0.339 and p = 0.020, r = 0.328, respectively). Higher Kellgren-Lawrence grades were also associated with cyst presence (p = 0.001). Gender correlated with knee measurements, showing smaller knee dimensions in women (p < 0.001).</p><p><strong>Conclusion: </strong>This study found no direct association between medial knee bone morphology and the presence of popliteal cysts. However, cyst size increased with age and degenerative changes, suggesting that inflammation and joint degeneration may play a significant role in cyst development. Further studies with larger cohorts are required to validate these findings.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1863-1871"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opportunistic screening for osteoporosis: validation study for L1 bone density measurements using contrast-enhanced chest and abdominal CTs.","authors":"Arnau Hanly, Soterios Gyftopoulos, Casey E Pelzl, Wei He, Connie Y Chang","doi":"10.1007/s00256-025-04892-8","DOIUrl":"10.1007/s00256-025-04892-8","url":null,"abstract":"<p><strong>Objective: </strong>To retrospectively validate the diagnostic power of attenuation values on chest and abdomen/pelvis CECTs, together and separately, compared with dual-energy X-ray absorptiometry (DEXA)-determined osteoporosis diagnoses, and to determine thresholds for accurate osteoporosis diagnosis.</p><p><strong>Materials and methods: </strong>Subjects were identified using the electronic health record. Included patients received DEXA and CECT scans within 60 days of each other. Patients were excluded if taking osteoporosis medication, undergoing dialysis, receiving hormone or cancer therapy, had a history of cancer, osseous metastases, fractures, or compressions. Minimum, mean, and maximum CECT attenuation values of L1 trabecular bone axial cross-sections were measured by a non-physician in Hounsfield units (HUs) using an elliptical region of interest (ROI) tool. DEXA diagnoses were dichotomized as positive (osteoporosis) or negative (osteopenia/normal). The area under the receiver-operator characteristic curves (AUCs) were compared to identify ideal CECT attenuation thresholds.</p><p><strong>Results: </strong>Two hundred nineteen subjects (mean age 66 ± 0.6 [range 35-92]; 196 (89%) females and 23 (11%) males) were included for analysis. Thirty-one (14%) subjects were positive and 188 (86%) were negative for osteoporosis. Minimum, mean, and maximum combined chest and abdomen/pelvis attenuation values demonstrated AUCs of 0.75 (95% CI 0.67-0.84), 0.931 (95% CI 0.88-0.99), and 0.82 (95% CI 0.73-0.90). The optimal mean attenuation threshold for osteoporosis diagnosis was 120 HU (84% sensitive, 90% specific). There was no statistical difference in diagnostic power between mean attenuation values of chest and abdomen/pelvis CECTs.</p><p><strong>Conclusion: </strong>CECT mean attenuation values of either chest or abdomen/pelvis CECTs could be used as appropriate thresholds in screening for osteoporosis.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1887-1895"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Test Yourself Question: An elderly man presenting with features of cauda equina.","authors":"Muhammad Riaz, Hasaam Uldin, Scott Evans, Petra Balogh, Rajesh Botchu","doi":"10.1007/s00256-025-04886-6","DOIUrl":"10.1007/s00256-025-04886-6","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1959-1961"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A soft tissue lesion caused by Mycobacterium malmoense.","authors":"Maria Rodrigues, Simranjeet Kaur, Ali Al Khader, Adrienne M Flanagan, Karen Shepherd, Naomi Winn","doi":"10.1007/s00256-025-04912-7","DOIUrl":"10.1007/s00256-025-04912-7","url":null,"abstract":"<p><p>We report a rare case of a soft tissue infection caused by Mycobacterium malmoense in an 88-year-old woman, a former farmer. The patient presented with a non-healing lesion on her right forearm, which had been increasing in size over 2 months. Ultrasound and magnetic resonance imaging (MRI) showed subcutaneous nodular lesions, and the patient was referred to the multidisciplinary soft tissue tumour meeting at our institution. A biopsy was performed, and the histopathological examination revealed granulomatous inflammation with abundant Ziehl-Neelsen-positive microorganisms, indicative of a mycobacterial infection. A polymerase chain reaction (PCR) assay identified Mycobacterium malmoense as the infective agent. Combined antibiotic treatment resulted in a significant clinical improvement. This case raises awareness about this uncommon pathogen, particularly causing soft tissue infections. The report also highlights the features on imaging, its treatment, and the appropriate utilisation of technology to reach a correct diagnosis.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1977-1982"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}