{"title":"Ultrasonography in the assessment of calcium pyrophosphate deposition disease.","authors":"Janeth Yinh, Mohamed Jarraya, Ali Guermazi","doi":"10.1007/s00256-025-04883-9","DOIUrl":null,"url":null,"abstract":"<p><p>Calcium pyrophosphate deposition (CPPD) disease is an arthropathy with increasing prevalence in the aging population that is associated with significant musculoskeletal morbidity. Although synovial fluid analysis (SFA) has been considered the gold standard for diagnosis, imaging is gaining an increasing role in the diagnosis and assessment of CPPD disease. Ultrasound (US) has proven to be useful in identifying calcium crystals while simultaneously assessing the surrounding inflammatory and structural damage consequent to calcific tissue deposition. Point-of-care ultrasound has the additional benefit of focusing the US evaluation to targeted symptomatic structures at the bedside, as well as allowing the sonographer to additionally scan joints frequently affected in CPPD disease to enhance the diagnostic utility of US. Furthermore, diagnostic and therapeutic procedures under US guidance can increase the yield of a diagnostic aspiration in CPPD disease and provide a therapeutic role in facilitating accurate delivery of medication in difficult to reach structures. Understanding the utility and limitations of US is essential to optimize the benefits of this imaging modality in the evaluation of CPPD disease.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Skeletal Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00256-025-04883-9","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Calcium pyrophosphate deposition (CPPD) disease is an arthropathy with increasing prevalence in the aging population that is associated with significant musculoskeletal morbidity. Although synovial fluid analysis (SFA) has been considered the gold standard for diagnosis, imaging is gaining an increasing role in the diagnosis and assessment of CPPD disease. Ultrasound (US) has proven to be useful in identifying calcium crystals while simultaneously assessing the surrounding inflammatory and structural damage consequent to calcific tissue deposition. Point-of-care ultrasound has the additional benefit of focusing the US evaluation to targeted symptomatic structures at the bedside, as well as allowing the sonographer to additionally scan joints frequently affected in CPPD disease to enhance the diagnostic utility of US. Furthermore, diagnostic and therapeutic procedures under US guidance can increase the yield of a diagnostic aspiration in CPPD disease and provide a therapeutic role in facilitating accurate delivery of medication in difficult to reach structures. Understanding the utility and limitations of US is essential to optimize the benefits of this imaging modality in the evaluation of CPPD disease.
期刊介绍:
Skeletal Radiology provides a forum for the dissemination of current knowledge and information dealing with disorders of the musculoskeletal system including the spine. While emphasizing the radiological aspects of the many varied skeletal abnormalities, the journal also adopts an interdisciplinary approach, reflecting the membership of the International Skeletal Society. Thus, the anatomical, pathological, physiological, clinical, metabolic and epidemiological aspects of the many entities affecting the skeleton receive appropriate consideration.
This is the Journal of the International Skeletal Society and the Official Journal of the Society of Skeletal Radiology and the Australasian Musculoskelelal Imaging Group.