Skeletal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-04DOI: 10.1007/s00256-024-04837-7
Nana Zhu, Feige Niu, Shuxuan Fan, Xianghong Meng, Yongcheng Hu, Jun Han, Zhi Wang
{"title":"Predicting progression-free survival in sarcoma using MRI-based automatic segmentation models and radiomics nomograms: a preliminary multicenter study.","authors":"Nana Zhu, Feige Niu, Shuxuan Fan, Xianghong Meng, Yongcheng Hu, Jun Han, Zhi Wang","doi":"10.1007/s00256-024-04837-7","DOIUrl":"10.1007/s00256-024-04837-7","url":null,"abstract":"<p><strong>Objectives: </strong>Some sarcomas are highly malignant, associated with high recurrence despite treatment. This multicenter study aimed to develop and validate a radiomics signature to estimate sarcoma progression-free survival (PFS).</p><p><strong>Materials and methods: </strong>The study retrospectively enrolled 202 consecutive patients with pathologically diagnosed sarcoma, who had pre-treatment axial fat-suppressed T2-weighted images (FS-T2WI), and included them in the ROI-Net model for training. Among them, 120 patients were included in the radiomics analysis, all of whom had pre-treatment axial T1-weighted and transverse FS-T2WI images, and were randomly divided into a development group (n = 96) and a validation group (n = 24). In the development cohort, Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression was used to develop the radiomics features for PFS prediction. By combining significant clinical features with radiomics features, a nomogram was constructed using Cox regression.</p><p><strong>Results: </strong>The proposed ROI-Net framework achieved a Dice coefficient of 0.820 (0.791-0.848). The radiomics signature based on 21 features could distinguish high-risk patients with poor PFS. Univariate Cox analysis revealed that peritumoral edema, metastases, and the radiomics score were associated with poor PFS and were included in the construction of the nomogram. The Radiomics-T1WI-Clinical model exhibited the best performance, with AUC values of 0.947, 0.907, and 0.924 at 300 days, 600 days, and 900 days, respectively.</p><p><strong>Conclusion: </strong>The proposed ROI-Net framework demonstrated high consistency between its segmentation results and expert annotations. The radiomics features and the combined nomogram have the potential to aid in predicting PFS for patients with sarcoma.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1417-1427"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2024-10-13DOI: 10.1007/s00256-024-04814-0
Sindhura Mettu, Sonal Saran, Kapil Shirodkar, Ankit B Shah, Bipin R Shah, Iqbal Siddi Ganie, K J S S Raghu Teja, Karthikeyan P Iyengar, Rajesh Botchu
{"title":"Anatomy and pathology of adductor canal (Hunter's canal).","authors":"Sindhura Mettu, Sonal Saran, Kapil Shirodkar, Ankit B Shah, Bipin R Shah, Iqbal Siddi Ganie, K J S S Raghu Teja, Karthikeyan P Iyengar, Rajesh Botchu","doi":"10.1007/s00256-024-04814-0","DOIUrl":"10.1007/s00256-024-04814-0","url":null,"abstract":"<p><p>Adductor canal (Hunter's canal) pathologies are often underdiagnosed, with the saphenous nerve being the most commonly affected. While uncommon, involvement of the femoral artery and vein can cause severe and irreversible complications if not detected early. Significant attention must be given to adductor canal pathologies because the musculoaponeurotic tunnel is predominantly fibrotic with minimal adipose tissue. As a result, any edema or space-occupying lesion can lead to early compression of the structures within the adductor canal. Incorporating adductor canal syndrome into the imaging differential diagnosis is essential. For diagnosing and sometimes managing these conditions. In this article, we describe the anatomy and spectrum of pathologies involving the Hunter's canal.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1169-1177"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142474246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2024-11-19DOI: 10.1007/s00256-024-04829-7
Ruoxun Zi, Batool Abbas, Bili Wang, Jerzy Walczyk, Ryan Brown, Catherine Petchprapa, James Fishbaugh, Guido Gerig, Kai Tobias Block, Riccardo Lattanzi
{"title":"High-resolution volumetric dynamic magnetic resonance imaging of the wrist using an 8-channel flexible receive coil.","authors":"Ruoxun Zi, Batool Abbas, Bili Wang, Jerzy Walczyk, Ryan Brown, Catherine Petchprapa, James Fishbaugh, Guido Gerig, Kai Tobias Block, Riccardo Lattanzi","doi":"10.1007/s00256-024-04829-7","DOIUrl":"10.1007/s00256-024-04829-7","url":null,"abstract":"<p><strong>Objective: </strong>Real-time imaging is useful for the evaluation of wrist instability. However, currently available real-time magnetic resonance imaging (MRI) methods are limited due to their 2D nature or provide insufficient temporal resolution and image quality for quantitative kinematic analysis. This work introduces a novel approach for volumetric dynamic MRI of the wrist joint during active motion and demonstrates the feasibility of tracking carpal bone motion.</p><p><strong>Materials and methods: </strong>A flexible 8-element 3 T wrist receive coil and 3D-printed support platform for guiding motion were designed for dynamic wrist imaging. 2D real-time images were acquired using a fat-saturated FLASH sequence with radial sampling and reconstructed with the GRASP algorithm. Corresponding volumetric dynamic wrist images were obtained by assembling 2D real-time images into 3D snapshots using autodetected MRI-visible markers for slice alignment. The proposed method was demonstrated for radial-ulnar deviation on five healthy volunteers.</p><p><strong>Results: </strong>The flexible wrist coil provided high SNR while allowing a wide range of wrist movements. 2D real-time wrist images were acquired with a temporal resolution of 48 ms/frame with negligible streaking artifacts. Carpal bones and metacarpal bones were properly aligned in the assembled dynamic volumes for all five subjects. The excellent bone-to-tissue contrast enabled accurate segmentation of the individual carpal bones on the assembled dynamic volumes.</p><p><strong>Conclusion: </strong>This work introduces a novel wrist coil and demonstrates that real-time volumetric dynamic examination of the moving wrist is feasible. The achieved image quality and high temporal resolution could enable automatic segmentation of carpal bones and quantitative kinematic assessment for evaluating wrist instability.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1291-1299"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Histopathologic confirmation of subchondral fracture in symptomatic pre-collapse osteonecrosis of the femoral head with bone marrow edema on magnetic resonance imaging.","authors":"Yusuke Ayabe, Goro Motomura, Ryosuke Yamaguchi, Takeshi Utsunomiya, Kosei Sakamoto, Yasuharu Nakashima","doi":"10.1007/s00256-024-04846-6","DOIUrl":"10.1007/s00256-024-04846-6","url":null,"abstract":"<p><strong>Objective: </strong>The presence of bone marrow edema on magnetic resonance imaging (MRI) in pre-collapse osteonecrosis of the femoral head is suggested to be a sign of occult subchondral fracture; however, to our knowledge, there are no histopathological studies verifying this. This study aimed to histopathologically verify the presence of subchondral fracture at the lateral necrotic boundary in symptomatic pre-collapse osteonecrosis of the femoral head with bone marrow edema on MRI.</p><p><strong>Materials and methods: </strong>Of 149 consecutive necrotic femoral heads resected during total hip arthroplasty at our hospital from January 2019 to June 2024, we included 13 femoral heads that did not show apparent collapse on preoperative radiographs and exhibited bone marrow edema on MRI. Continuous coronal-slice hematoxylin and eosin-stained specimens of each femoral head were examined for the presence of subchondral fracture. Bone microarchitectures around subchondral fractures were measured using micro-computed tomography (CT) images.</p><p><strong>Results: </strong>In all femoral heads, subchondral fractures were histopathologically confirmed at the lateral junction between the reparative and the necrotic zone. On micro-CT, bone volume fraction, trabecular thickness, and bone mineral density of the reparative zone adjacent to the subchondral fracture were all significantly higher than those of the necrotic zone adjacent to the subchondral fracture.</p><p><strong>Conclusion: </strong>Subchondral fracture invariably existed when bone marrow edema was present on MRI during pre-collapse osteonecrosis of the femoral head. When bone marrow edema is observed on MRI, it should be known that subchondral fracture has already occurred, even if femoral head collapse is unclear on radiographs.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1275-1281"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2025-03-26DOI: 10.1007/s00256-025-04918-1
Renata Vidal Leão, Leandro Ejnisman, Renata Fernandes Batista Pereira, Paulo Victor Partezani Helito
{"title":"Response to the LETTER TO THE EDITOR on the Paper \"Imaging evaluation of hip capsule disorders: a comprehensive review\".","authors":"Renata Vidal Leão, Leandro Ejnisman, Renata Fernandes Batista Pereira, Paulo Victor Partezani Helito","doi":"10.1007/s00256-025-04918-1","DOIUrl":"10.1007/s00256-025-04918-1","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1303-1304"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2024-11-19DOI: 10.1007/s00256-024-04832-y
Paulo Miro, Amanda Crawford, Megan K Mills, Volker Schöffl
{"title":"Imaging of primary periphyseal finger stress injuries in climbers.","authors":"Paulo Miro, Amanda Crawford, Megan K Mills, Volker Schöffl","doi":"10.1007/s00256-024-04832-y","DOIUrl":"10.1007/s00256-024-04832-y","url":null,"abstract":"<p><p>Periphyseal stress injuries (PPSIs) in young rock climbers are gaining recognition due to the surge in popularity of the sport. These injuries, occurring near the growth plates of fingers, pose diagnostic challenges due to their subtle presentation and potential long-term complications if left untreated. This review emphasizes the importance of radiologists' awareness of PPSIs, covering their anatomy, biomechanics, and imaging findings. Techniques like the \"crimp-grip\" in climbing exacerbate the vulnerability of the physis, leading to repetitive stress injuries. Imaging modalities such as radiography, MRI, CT, and ultrasound play crucial roles in diagnosis, each with its advantages and limitations. While radiographs remain a cost-effective initial choice, MRI offers detailed soft tissue evaluation and can detect occult injuries. Understanding the pathophysiology and imaging characteristics of PPSIs is essential for early detection and appropriate management to prevent long-term skeletal deformities and growth disturbances in young climbers.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1215-1224"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2024-11-21DOI: 10.1007/s00256-024-04833-x
Parya Valizadeh, Payam Jannatdoust, Mohammad-Taha Pahlevan-Fallahy, Sara Bagherieh, Paniz Adli, Melika Amoukhteh, Amir Hassankhani, George R Matcuk, Ali Gholamrezanezhad
{"title":"Diagnostic performance of dual-energy computed tomography in detecting anterior cruciate ligament injuries: a systematic review and meta-analysis.","authors":"Parya Valizadeh, Payam Jannatdoust, Mohammad-Taha Pahlevan-Fallahy, Sara Bagherieh, Paniz Adli, Melika Amoukhteh, Amir Hassankhani, George R Matcuk, Ali Gholamrezanezhad","doi":"10.1007/s00256-024-04833-x","DOIUrl":"10.1007/s00256-024-04833-x","url":null,"abstract":"<p><strong>Objective: </strong>Anterior cruciate ligament (ACL) injuries are common and lead to significant physical limitations. While MRI is the diagnostic gold standard, its use is restricted in acute trauma cases due to contraindications and longer imaging times. Dual-energy computed tomography (DECT) has emerged as a potential alternative. This meta-analysis evaluates the diagnostic accuracy of DECT for ACL injuries.</p><p><strong>Materials and methods: </strong>Following PRISMA guidelines, a comprehensive literature search was conducted using PubMed, Web of Science, Scopus, and Embase for studies published up to June 2024. Studies that provided diagnostic accuracy data for DECT in ACL ruptures were included. Metrics of diagnostic accuracy were aggregated using a bivariate random effects model.</p><p><strong>Results: </strong>The meta-analysis, which included five studies with a total of 191 patients, found that DECT had a pooled sensitivity of 88.1% (95% CI, 78.0-93.9%) and a specificity of 82.0% (95% CI, 62.0-92.7%) for diagnosing ACL ruptures, with an AUC of 0.92 (95% CI, 0.72-0.96). For complete ruptures, sensitivity was 83.2% (95% CI, 68.2-92.0%), and specificity was 94.9% (95% CI, 92.2-96.7%), with an AUC of 0.96 (95% CI, 0.81-0.98). In acute/subacute settings, sensitivity was 89.4% (95% CI, 76.8-95.6%), and specificity was 82.1% (95% CI, 56.2-94.2%), with an AUC of 0.93 (95% CI, 0.71-0.97).</p><p><strong>Conclusion: </strong>Our findings suggest that DECT is a valuable diagnostic tool for ACL injuries, particularly as an adjunct or alternative when MRI is unavailable or contraindicated, enabling timely and accurate diagnosis.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1247-1262"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12000185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating tibial rotation in recurrent patellar dislocation with four-dimensional computed tomography.","authors":"Kazuya Kaneda, Kengo Harato, Satoshi Oki, Yutaro Morishige, Shu Kobayashi, Masaya Nakamura, Takeo Nagura","doi":"10.1007/s00256-024-04817-x","DOIUrl":"10.1007/s00256-024-04817-x","url":null,"abstract":"<p><strong>Objective: </strong>This study is to investigate the three-dimensional (3D) kinematic changes in the knee joint in patients with recurrent patellar dislocation using four-dimensional computed tomography (4DCT) imaging and the 3D-3D surface registration technique.</p><p><strong>Materials and methods: </strong>Ten knees from nine patients with recurrent patellar dislocation and seven knees from seven controls (unaffected side of patients with unilateral anterior cruciate ligament injury) were analyzed using 4DCT. The patients were asked to extend their knees from 60° of flexion to full extension for 10 s in the CT gantry. We used the 3D-3D registration technique, and the 3D angles of the patella and tibia relative to the femur were evaluated.</p><p><strong>Results: </strong>In the dislocation group, the patellar lateral tilt increased as the knee extended. Significant differences were found between the two groups at 0°-20° of knee flexion. The tibia rotated externally as the knee extended in the dislocation group. Significant differences between the two groups were found at 0°-10° of knee flexion.</p><p><strong>Conclusion: </strong>This study demonstrated significant differences in the timing and magnitude of tibial external rotation between patients with recurrent patellar dislocation and controls. Specifically, the tibia began to externally rotate during the early phase of knee extension in the dislocation group. These findings provide new insights into knee kinematics that may inform future treatment strategies for patellar dislocation.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1283-1289"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2025-03-05DOI: 10.1007/s00256-025-04903-8
Manuela Gallo, Laura Manuela Olarte Bermúdez, Alejandra Duarte
{"title":"Commentary to: CT imaging fndings in symptomatic patients with and without revision surgery after reverse shoulder arthroplasty.","authors":"Manuela Gallo, Laura Manuela Olarte Bermúdez, Alejandra Duarte","doi":"10.1007/s00256-025-04903-8","DOIUrl":"10.1007/s00256-025-04903-8","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1305-1306"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-06-01Epub Date: 2024-11-29DOI: 10.1007/s00256-024-04841-x
L Haq, H Uldin, S Evans, A Patel, P Balogh, R Botchu
{"title":"Test Yourself Question: A young male with right shoulder pain.","authors":"L Haq, H Uldin, S Evans, A Patel, P Balogh, R Botchu","doi":"10.1007/s00256-024-04841-x","DOIUrl":"10.1007/s00256-024-04841-x","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"1313-1315"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}