Skeletal Radiology最新文献

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High prevalence of associated injuries in anterior cruciate ligament tears: A detailed magnetic resonance imaging analysis of 254 patients. 前十字韧带撕裂伴发损伤的高发率:对 254 名患者进行的详细磁共振成像分析。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-03-27 DOI: 10.1007/s00256-024-04665-9
Riccardo Cristiani, Fabian van de Bunt, Joanna Kvist, Anders Stålman
{"title":"High prevalence of associated injuries in anterior cruciate ligament tears: A detailed magnetic resonance imaging analysis of 254 patients.","authors":"Riccardo Cristiani, Fabian van de Bunt, Joanna Kvist, Anders Stålman","doi":"10.1007/s00256-024-04665-9","DOIUrl":"10.1007/s00256-024-04665-9","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the type and prevalence of associated injuries by using magnetic resonance imaging (MRI) in patients with anterior cruciate ligament (ACL) tears.</p><p><strong>Methods: </strong>Data from the Natural Corollaries and Recovery after ACL injury multicenter longitudinal cohort study were analyzed. Between May 2016 and October 2018, patients aged between 15 and 40 years, who had experienced an ACL tear within the last 6 weeks and sought medical attention at one of seven healthcare clinics in Sweden, were invited to participate. The mean time from injury to MRI was 19.6 ± 15.2 days. An orthopedic knee surgeon and a musculoskeletal radiologist reviewed all the MRI scans. The following structures were assessed: posterior cruciate ligament (PCL), medial collateral ligament (MCL) complex, lateral collateral ligament (LCL), popliteus tendon, medial meniscus (MM), lateral meniscus (LM), and cartilage. In addition, the presence of bone bruising, impaction fractures in the lateral femoral condyle (LFC) or posterolateral tibia (PLT), and Segond fractures were also assessed.  RESULTS: A total of 254 patients (48.4% males) with a mean age of 25.4 ± 7.1 years were included. The prevalence of associated injuries was as follows: PCL (0.4%), MCL {41.3% [superficial MCL and deep MCL (dMCL) 16.5%; isolated dMCL 24.8%]}, LCL (2.4%), MM (57.4%), LM (25.2%), cartilage (15.0%), bone bruising (92.9%), impaction fracture in the LFC (45.7%) and PLT (4.7%), and Segond fracture (7.5%).</p><p><strong>Conclusions: </strong>The prevalence of associated injuries in patients with ACL tears was high. The findings reported in this study may serve as a reference tool for orthopedic surgeons and radiologists in the diagnosis of associated injuries using MRI in patients with ACL tears.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phalangeal microgeodic syndrome: a paediatric case series. 趾骨小关节综合征:儿科病例系列。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-01-20 DOI: 10.1007/s00256-024-04581-y
Jasmine Zacharias, Uday Mandalia, Jason Palman, Fatima Kagalwala, Cecil Bernard Colaco, Janani K Pillai
{"title":"Phalangeal microgeodic syndrome: a paediatric case series.","authors":"Jasmine Zacharias, Uday Mandalia, Jason Palman, Fatima Kagalwala, Cecil Bernard Colaco, Janani K Pillai","doi":"10.1007/s00256-024-04581-y","DOIUrl":"10.1007/s00256-024-04581-y","url":null,"abstract":"<p><p>We present the clinical and radiological characteristics of phalangeal microgeodic syndrome in a cluster of five children during the second peak of COVID-19 pandemic in the UK. Each child presented with phalangeal swelling and erythema, prompting a comprehensive multi-disciplinary team review to analyse the clinical presentation, blood test results and imaging. The cohort's average age was 14.1 years, ranging from 10.4 to 16.6 years, with two girls and three boys. Four children experienced phalangeal involvement in the hands, whilst one was affected solely in the feet. A rheumatological work-up was performed for all. Hand X-rays performed on three children revealed distinct radiographic features like microgeodes, subperiosteal bone resorption and rarefaction in two cases. However, further MRI showed extensive changes closely correlated with the clinical signs of cutaneous vasculopathic rashes. The MRI abnormalities were notable, encompassing marrow oedema primarily affecting metaphyses and epiphyses, displaying broad transition zones. Soft tissue swelling and cortical erosions were also observed. These MRI features proved more pathognomonic in the acute clinical context. The study concluded that phalangeal microgeodic syndrome, characterised by digital swelling and erythema, might not be adequately assessed by plain X-rays. The more comprehensive MRI features, including marrow oedema and soft tissue abnormalities, appeared to be more indicative in diagnosing the condition. Considering the rarity of this syndrome and its temporal association with the COVID-19 pandemic, the study hypothesised that COVID-related thrombophilia and immune-mediated vasculopathy might act as crucial triggers for the active bony manifestations seen in this syndrome. KEY POINTS: • PMS is a rare, predominantly paediatric condition, of unknown aetiology which affects the digits. • Laboratory investigations are generally negative; however, in the appropriate clinical context, the X-ray findings of microgeodes and pattern of bone marrow oedema seen on MRI are pathognomonic. • Considering the rarity of PMS and temporal association with the COVID-19 pandemic, COVID vasculopathy may represent a previously unrecognised aetiology for PMS.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139512977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extremity radiographs derived from low-dose ultra-high-resolution CT: a phantom study. 从低剂量超高分辨率 CT 导出的四肢放射影像:一项模型研究。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-02-03 DOI: 10.1007/s00256-024-04600-y
Andrew M Hernandez, Christopher O Bayne, Cyrus Bateni, Ramit Lamba, John M Boone
{"title":"Extremity radiographs derived from low-dose ultra-high-resolution CT: a phantom study.","authors":"Andrew M Hernandez, Christopher O Bayne, Cyrus Bateni, Ramit Lamba, John M Boone","doi":"10.1007/s00256-024-04600-y","DOIUrl":"10.1007/s00256-024-04600-y","url":null,"abstract":"<p><strong>Objective: </strong>To demonstrate the potential of low-dose ultra-high-resolution CT (UHRCT) images to generate high-quality radiographic images on extremity phantoms and to estimate the radiation dose required for this.</p><p><strong>Materials and methods: </strong>A hand and knee phantom containing real human bones was imaged on an UHRCT scanner at full-dose, half-dose, and quarter-dose levels using a high-resolution extremity protocol. The raw data was reconstructed using both filtered back projection (FBP) and an iterative reconstruction algorithm (AIDR3D). Using custom designed software, each CT volume data set was converted to attenuation coefficients, and then a synthesized radiograph (synDX) was generated by forward projecting the volume data sets from a point source onto a 2D synthetic detector. The signal-to-noise ratio (SNR) was measured in the synDXs across all dose levels and the root-mean-squared error (RMSE) was computed with the FD synDXs as the reference.</p><p><strong>Results: </strong>The proposed workflow generates high-quality synDXs at any arbitrary angle. For FBP, the SNR largely tracked with the radiation dose levels for both the knee and hand phantoms. For the knee phantom, iterative reconstruction provided a 6.1% higher SNR when compared to FBP. The RMSE was overall higher for the lowest dose levels and monotonically decreased with increasing dose. No substantial differences were observed qualitatively in the visualization of skeletal detail of the phantoms.</p><p><strong>Conclusion: </strong>The fine detail provided by UHRCT acquisitions of extremities facilitates the ability to generate quality radiographs, potentially eliminating the need for additional scanning on a conventional digital radiography system.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent benign fibrous histiocytoma of the bone benefits from denosumab followed by malignant transformation: a case report. 复发性骨良性纤维组织细胞瘤受益于地诺单抗后发生恶性转化:病例报告。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-02-19 DOI: 10.1007/s00256-024-04610-w
Wetterwald Laureline, Omoumi Patrick, Nguyen Tu, Cherix Stephane, Dolcan Ana, Ferraro Daniela, Saglietti Chiara, Letovanec Igor, Digklia Antonia
{"title":"Recurrent benign fibrous histiocytoma of the bone benefits from denosumab followed by malignant transformation: a case report.","authors":"Wetterwald Laureline, Omoumi Patrick, Nguyen Tu, Cherix Stephane, Dolcan Ana, Ferraro Daniela, Saglietti Chiara, Letovanec Igor, Digklia Antonia","doi":"10.1007/s00256-024-04610-w","DOIUrl":"10.1007/s00256-024-04610-w","url":null,"abstract":"<p><p>Benign fibrous histiocytoma of the bone (BFHB) is a rare mesenchymal tumor, representing less than 1% of all benign bone tumors. This controversial entity is characterized by a mixture of fibroblasts arranged in a storiform pattern, varying amounts of osteoclast-type giant cells and foamy macrophages. Curettage or simple resection is usually curative. However, it was reported that up to 11% of the patients suffer from relapse. Here, we report a case of malignant transformation of BFHB after long-lasting disease stabilization under denosumab therapy.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance of thoracic ultrasonography compared with chest radiography for the detection of rib fractures using computed tomography as a reference standard. 以计算机断层扫描为参考标准,比较胸部超声波与胸部放射摄影在检测肋骨骨折方面的性能。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-03-19 DOI: 10.1007/s00256-024-04658-8
Evangelia E Vassalou, Iraklis Perysinakis, Michail E Klontzas, Eelco de Bree, Apostolos H Karantanas
{"title":"Performance of thoracic ultrasonography compared with chest radiography for the detection of rib fractures using computed tomography as a reference standard.","authors":"Evangelia E Vassalou, Iraklis Perysinakis, Michail E Klontzas, Eelco de Bree, Apostolos H Karantanas","doi":"10.1007/s00256-024-04658-8","DOIUrl":"10.1007/s00256-024-04658-8","url":null,"abstract":"<p><strong>Objective: </strong>Although there is growing evidence that ultrasonography is superior to X-ray for rib fractures' detection, X-ray is still indicated as the most appropriate method. This has partially been attributed to a lack of studies using an appropriate reference modality. We aimed to compare the diagnostic accuracy of ultrasonography and X-ray in the detection of rib fractures, considering CT as the reference standard.</p><p><strong>Materials and methods: </strong>Within a 2.5-year period, all consecutive patients with clinically suspected rib fracture(s) following blunt chest trauma and available posteroanterior/anteroposterior X-ray and thoracic CT were prospectively studied and planned to undergo thoracic ultrasonography, by a single operator. All imaging examinations were evaluated for cortical rib fracture(s), and their location was recorded. The cartilaginous rib portions were not assessed. CTs and X-rays were evaluated retrospectively. Concomitant thoracic/extra-thoracic injuries were assessed on CT. Comparisons were performed with the Mann-Whitney U test and Fisher's exact test.</p><p><strong>Results: </strong>Fifty-nine patients (32 males, 27 females; mean age, 53.1 ± 16.6 years) were included. CT, ultrasonography, and X-ray (40 posteroanterior/19 anteroposterior views) diagnosed 136/122/42 rib fractures in 56/54/27 patients, respectively. Ultrasonography and X-ray had sensitivity of 100%/40% and specificity of 89.7%/30.9% for rib fractures' detection. Ultrasound accuracy was 94.9% compared to 35.4% for X-rays (P < .001) in detecting individual rib fractures. Most fractures involved the 4th-9th ribs. Upper rib fractures were most commonly overlooked on ultrasonography. Thoracic cage/spine fractures and haemothorax represented the most common concomitant injuries.</p><p><strong>Conclusion: </strong>Ultrasonography appeared to be superior to X-ray for the detection of rib fractures with regard to a reference CT.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140158981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Swollen and painful distal phalanx. 远端指骨肿胀、疼痛。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-02-08 DOI: 10.1007/s00256-024-04612-8
Thomas Saliba, Grammatina Boitsios, Paolo Simoni
{"title":"Swollen and painful distal phalanx.","authors":"Thomas Saliba, Grammatina Boitsios, Paolo Simoni","doi":"10.1007/s00256-024-04612-8","DOIUrl":"10.1007/s00256-024-04612-8","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automatic estimation of hallux valgus angle using deep neural network with axis-based annotation. 利用基于轴标注的深度神经网络自动估算外翻角度。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-03-13 DOI: 10.1007/s00256-024-04618-2
Ryutaro Takeda, Hiroyasu Mizuhara, Akihiro Uchio, Toshiko Iidaka, Kenta Makabe, Taro Kasai, Yasunori Omata, Noriko Yoshimura, Sakae Tanaka, Takumi Matsumoto
{"title":"Automatic estimation of hallux valgus angle using deep neural network with axis-based annotation.","authors":"Ryutaro Takeda, Hiroyasu Mizuhara, Akihiro Uchio, Toshiko Iidaka, Kenta Makabe, Taro Kasai, Yasunori Omata, Noriko Yoshimura, Sakae Tanaka, Takumi Matsumoto","doi":"10.1007/s00256-024-04618-2","DOIUrl":"10.1007/s00256-024-04618-2","url":null,"abstract":"<p><strong>Objectives: </strong>We developed the deep neural network (DNN) model to automatically measure hallux valgus angle (HVA) and intermetatarsal angle (IMA) on foot radiographs. The objective is to assess the accuracy of the model by comparing to the manual measurement of foot and ankle surgeons.</p><p><strong>Materials and methods: </strong>A DNN was developed to predict the bone axes of the first proximal phalanx and all metatarsals from the first to the fifth in foot radiographs. The dataset used for model development consisted of 1798 radiographs collected from a population-based cohort and patients at our foot and ankle clinic. The retrospective validation cohort comprised of 92 radiographs obtained from 92 consecutive patients visiting our foot and ankle clinic. The mean absolute error (MAE) between automatic measurements by the model and the median of manual measurements by three foot and ankle surgeons was compared to 3° using one-tailed t-test and was also compared to the inter-rater difference in manual measurements among the three surgeons using two-tailed paired t-test.</p><p><strong>Results: </strong>The MAE for HVA was 1.3° (upper limit of 95% CI 1.6°), and this was significantly smaller than the inter-rater difference of 2.0 ± 0.2° among the surgeons, demonstrating the superior accuracy of the model. In contrast, the MAE for IMA was 0.8° (upper limit of 95% CI 1.0°) that showed no significant difference from the inter-rater difference of 1.0 ± 0.1° among the surgeons.</p><p><strong>Conclusion: </strong>Our model demonstrated the ability to measure the HVA and IMA with an accuracy comparable to that of specialists.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140120575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Density Screening Rates Among Medicare Beneficiaries: An Analysis with a focus on Asian Americans. 医疗保险受益人的骨密度筛查率:以亚裔美国人为重点的分析。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-03-09 DOI: 10.1007/s00256-024-04643-1
Soterios Gyftopoulos, Casey E Pelzl, Madalena Da Silva Cardoso, Juliana Xie, Simona C Kwon, Connie Y Chang
{"title":"Bone Density Screening Rates Among Medicare Beneficiaries: An Analysis with a focus on Asian Americans.","authors":"Soterios Gyftopoulos, Casey E Pelzl, Madalena Da Silva Cardoso, Juliana Xie, Simona C Kwon, Connie Y Chang","doi":"10.1007/s00256-024-04643-1","DOIUrl":"10.1007/s00256-024-04643-1","url":null,"abstract":"<p><strong>Purpose: </strong>To report osteoporosis screening utilization rates among Asian American (AsA) populations in the USA.</p><p><strong>Methods: </strong>We retrospectively assessed the use of dual-energy X-ray absorptiometry (DXA) screening using the Medicare 5% Research Identifiable Files. Using Current Procedural Terminology (CPT) codes indicative of a DXA scan, we identified patients recommended for DXA screening according to the ACR-SPR-SSR Practice Parameters (females ≥ 65 years, males ≥ 70 years). Sociodemographic factors and their association with screening were evaluated using chi-square tests.</p><p><strong>Results: </strong>There were 80,439 eligible AsA beneficiaries, and 12,102 (15.1%) received osteoporosis screening. DXA rate for women was approximately four times greater than the rate for men (19.8% vs. 5.0%; p < 0.001). AsA beneficiaries in zip codes with higher mean household income (MHI) were more likely to have DXA than those in lower MHI areas (17.6% vs. 14.3%, p < 0.001). AsA beneficiaries aged < 80 were more likely to receive DXA (15.5%) than those aged ≥ 80 (14.1%, p < 0.001). There were 2,979,801 eligible non-AsA beneficiaries, and 496,957 (16.7%) received osteoporosis screening during the study period. Non-Hispanic white beneficiaries had the highest overall screening rate (17.5%), followed by North American Native (13.0%), Black (11.8%), and Hispanic (11.1%) beneficiaries. Comparing AsA to non-AsA populations, there were significantly lower DXA rates among AsA beneficiaries when controlling for years of Medicare eligibility, patient age, sex, location, and mean income (p < 0.001).</p><p><strong>Conclusion: </strong>We found lower than expected DXA screening rates for AsA patients. A better understanding of the barriers and facilitators to AsA osteoporosis screening is needed to improve patient care.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140068691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative MRI assessment of joint effusion using T2-relaxometry at 3 Tesla: a feasibility and reproducibility study. 在 3 特斯拉下使用 T2-松弛测量法对关节积液进行磁共振成像定量评估:一项可行性和可重复性研究。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-03-21 DOI: 10.1007/s00256-024-04652-0
Flora H P van Leeuwen, Beatrice Lena, Eline D P van Bergen, Janoah J van Klei, Merel A Timmer, Lize F D van Vulpen, Kathelijn Fischer, Pim A de Jong, Clemens Bos, Wouter Foppen
{"title":"Quantitative MRI assessment of joint effusion using T2-relaxometry at 3 Tesla: a feasibility and reproducibility study.","authors":"Flora H P van Leeuwen, Beatrice Lena, Eline D P van Bergen, Janoah J van Klei, Merel A Timmer, Lize F D van Vulpen, Kathelijn Fischer, Pim A de Jong, Clemens Bos, Wouter Foppen","doi":"10.1007/s00256-024-04652-0","DOIUrl":"10.1007/s00256-024-04652-0","url":null,"abstract":"<p><strong>Objective: </strong>T2-relaxometry could differentiate between physiological and haemorrhagic joint effusion (≥ 5% blood) in vitro. Are quantitative T2-relaxation time measurements of synovial fluid feasible and reproducible in vivo in clinically bleed-free joints of men with haemophilia?</p><p><strong>Materials and methods: </strong>In this cross-sectional study, we measured T2-relaxation times of synovial fluid in clinically bleed-free ankles, knees or elbows of men with severe haemophilia A using a T2-mapping sequence (duration ≤ 7 min) at 3 Tesla MRI. Manual and circular regions of interest (ROI) were drawn in the synovial fluid of each joint by two independent observers to measure T2-relaxation times. Measurement feasibility was expressed as the success rate of the measurements by both observers. The interobserver and intraobserver reproducibility of the measurements were evaluated by the intraclass correlation coefficient of absolute agreement (ICC) and the limits of agreement (LoA) from Bland Altman analysis.</p><p><strong>Results: </strong>We evaluated 39 clinically bleed-free joints (11 ankles, 12 knees, 16 elbows) of 39 men (median age, 24 years; range 17-33) with severe haemophilia A. The success rate of the T2-measurements was ≥ 90%. Interobserver reliability was good to excellent (manual ROI: ICC = 0.92, 95% CI 0.76-0.97; circular ROI: ICC = 0.82, 95% CI 0.66-0.91) and interobserver agreement was adequate (manual ROI: LoA = 71 ms; circular ROI: LoA = 146 ms). Intraobserver reliability was good to excellent (manual ROI: ICC = 0.78, 95% CI - 0.06-0.94; circular RO: ICC = 0.99, 95% CI 0.98-0.99) and intraobserver agreement was good (manual ROI: LoA = 63 ms; circular ROI: LoA = 41 ms).</p><p><strong>Conclusion: </strong>T2-relaxometry of synovial fluid in haemophilia patients is feasible with good interobserver and intraobserver reproducibility.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare presentation of a primary intraosseous glomus tumor in the humerus of a teenager. 罕见的青少年肱骨内原发性骨内胶质瘤。
IF 1.9 3区 医学
Skeletal Radiology Pub Date : 2024-11-01 Epub Date: 2024-02-01 DOI: 10.1007/s00256-024-04604-8
Kengo Kawaguchi, Kenichi Kohashi, Nokitaka Setsu, Koji Sagiyama, Makoto Endo, Takeshi Iwasaki, Yasuharu Nakashima, Yoshinao Oda
{"title":"Rare presentation of a primary intraosseous glomus tumor in the humerus of a teenager.","authors":"Kengo Kawaguchi, Kenichi Kohashi, Nokitaka Setsu, Koji Sagiyama, Makoto Endo, Takeshi Iwasaki, Yasuharu Nakashima, Yoshinao Oda","doi":"10.1007/s00256-024-04604-8","DOIUrl":"10.1007/s00256-024-04604-8","url":null,"abstract":"<p><p>A glomus tumor is a benign mesenchymal tumor comprised of cells that resemble the perivascular modified smooth muscle cells of the glomus body. Glomus tumors typically appear in the superficial lesions of the soft tissue in the extremities, such as the subungual region. However, their occurrence in the bone is rare, with only about 30 cases reported to date. Half of these cases involved the distal phalanges of the fingers or toes, with only three reported cases involving the long bones. Here, we present the first case, a primary glomus tumor in the humerus of a 14-year-old female. An osteolytic and cystic lesion was detected after a pathological fracture occurred during exercise. Despite the tumor's large size, no pathological findings indicated malignancy. The fracture healed through conservative treatment, while the tumor was effectively managed with curettage. Appropriate medical care can be provided to patients by focusing on pathological findings.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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