Science Advances最新文献_第8页

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.ads2217

Fanxi Sun, Ang Gao, Boyun Yan, Jing Zhang, Xiangru Wang, Hanjun Zhang, Dacheng Dai, Yonghao Zheng, Xu Deng, Chen Wei, Dongsheng Wang

{"title":"Self-adaptive photochromism","authors":"Fanxi Sun, Ang Gao, Boyun Yan, Jing Zhang, Xiangru Wang, Hanjun Zhang, Dacheng Dai, Yonghao Zheng, Xu Deng, Chen Wei, Dongsheng Wang","doi":"10.1126/sciadv.ads2217","DOIUrl":"10.1126/sciadv.ads2217","url":null,"abstract":"<div >Organisms with active camouflage ability exhibit changeable appearance with the switching of environments. However, manmade active camouflage systems heavily rely on integrating electronic devices, which encounters problems including a complex structure, poor usability, and high cost . In the current work, we report active camouflage as an intrinsic function of materials by proposing self-adaptive photochromism (SAP). The SAP materials were fabricated using donor-acceptor Stenhouse adducts (DASAs) as the negative photochromic phases and organic dyes as the fixed phases (nonphotochromic). Incident light with a specific wavelength induces <i>linear</i>-to-<i>cyclic</i> isomerization of DASAs, which generates an absorption gap at the wavelength and accordingly switches the color. The SAP materials are in the primary black state under dark and spontaneously switch to another color upon triggering by transmitted and reflected light in the background. SAP films and coatings were fabricated by incorporating polycaprolactone and are applicable to a wide variety of surfaces.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ads2217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-dimensional spin-orbital single-photon sources 高维自旋轨道单光子源

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adq6298

Yinhui Kan, Xujing Liu, Shailesh Kumar, Liudmilla F. Kulikova, Valery A. Davydov, Viatcheslav N. Agafonov, Sergey I. Bozhevolnyi

{"title":"High-dimensional spin-orbital single-photon sources","authors":"Yinhui Kan, Xujing Liu, Shailesh Kumar, Liudmilla F. Kulikova, Valery A. Davydov, Viatcheslav N. Agafonov, Sergey I. Bozhevolnyi","doi":"10.1126/sciadv.adq6298","DOIUrl":"10.1126/sciadv.adq6298","url":null,"abstract":"<div >Hybrid integration of solid-state quantum emitters (QEs) into nanophotonic structures opens enticing perspectives for exploiting multiple degrees of freedom of single-photon sources for on-chip quantum photonic applications. However, the state-of-the-art single-photon sources are mostly limited to two-level states or scalar vortex beams. Direct generation of high-dimensional structured single photons remains challenging, being still in its infancy. Here, we propose a general strategy to design highly entangled high-dimensional spin-orbital single-photon sources by taking full advantage of the spatial freedom to design QE-coupled composite (i.e., Moiré/multipart) metasurfaces. We demonstrate the generation of arbitrary vectorial spin-orbital photon emission in high-dimensional Hilbert spaces, mapping the generated states on hybrid-order Bloch spheres. We further realize single-photon sources of high-dimensional spin-orbital quantum emission and experimentally verify the entanglement of high-dimensional superposition states with high fidelity. We believe that the results obtained facilitate further progress in integrated solutions for the deployment of next-generation high-capacity quantum information technologies.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq6298","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endosomes serve as signaling platforms for RIG-I ubiquitination and activation 内体是 RIG-I 泛素化和激活的信号平台

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adq0660

Kuan-Ru Chen, Chia-Yu Yang, San-Ging Shu, Yin-Chiu Lo, Kuan-Wei Lee, Li-Chun Wang, Jia-Bao Chen, Meng-Cen Shih, Hung-Chun Chang, Yu-Ju Hsiao, Chao-Liang Wu, Tse-Hua Tan, Pin Ling

{"title":"Endosomes serve as signaling platforms for RIG-I ubiquitination and activation","authors":"Kuan-Ru Chen, Chia-Yu Yang, San-Ging Shu, Yin-Chiu Lo, Kuan-Wei Lee, Li-Chun Wang, Jia-Bao Chen, Meng-Cen Shih, Hung-Chun Chang, Yu-Ju Hsiao, Chao-Liang Wu, Tse-Hua Tan, Pin Ling","doi":"10.1126/sciadv.adq0660","DOIUrl":"10.1126/sciadv.adq0660","url":null,"abstract":"<div >RIG-I–like receptors (RLRs) are cytosolic RNA sensors critical for antiviral immunity. RLR activation is regulated by polyubiquitination and oligomerization following RNA binding. Yet, little is known about how RLRs exploit subcellular organelles to facilitate their posttranslational modifications and activation. Endosomal adaptor TAPE regulates the endosomal TLR and cytosolic RLR pathways. The potential interplay between RIG-I signaling and endosomes has been explored. Here, we report that endosomes act as platforms for facilitating RIG-I polyubiquitination and complex formation. RIG-I was translocated onto endosomes to form signaling complexes upon activation. Ablation of endosomes impaired RIG-I signaling to type I IFN activation. TAPE mediates the interaction and polyubiquitination of RIG-I and TRIM25. TAPE-deficient myeloid cells were defective in type I IFN activation upon RNA ligand and virus challenges. Myeloid TAPE deficiency increased the susceptibility to RNA virus infection in vivo. Our work reveals endosomes as signaling platforms for RIG-I activation and antiviral immunity.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq0660","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases 底物特异性和蛋白质稳定性驱动植物特异性 DNA 甲基转移酶的分化

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adr2222

Jianjun Jiang, Jia Gwee, Jian Fang, Sarah M. Leichter, Dean Sanders, Xinrui Ji, Jikui Song, Xuehua Zhong

{"title":"Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases","authors":"Jianjun Jiang, Jia Gwee, Jian Fang, Sarah M. Leichter, Dean Sanders, Xinrui Ji, Jikui Song, Xuehua Zhong","doi":"10.1126/sciadv.adr2222","DOIUrl":"10.1126/sciadv.adr2222","url":null,"abstract":"<div >DNA methylation is an important epigenetic mechanism essential for transposon silencing and genome integrity. Across evolution, the substrates of DNA methylation have diversified between kingdoms. In plants, chromomethylase3 (CMT3) and CMT2 mediate CHG and CHH methylation, respectively. However, how these two methyltransferases diverge on substrate specificities during evolution remains unknown. Here, we reveal that CMT2 originates from a duplication of an evolutionarily ancient CMT3 in flowering plants. Lacking a key arginine residue recognizing CHG in CMT2 impairs its CHG methylation activity in most flowering plants. An engineered V1200R mutation empowers CMT2 to restore CHG and CHH methylations in <i>Arabidopsis cmt2cmt3</i> mutant, testifying a loss-of-function effect for CMT2 during evolution. CMT2 has evolved a long and unstructured amino terminus critical for protein stability, especially under heat stress, and is plastic to tolerate various natural mutations. Together, this study reveals the mechanism of chromomethylase divergence for context-specific DNA methylation in plants and sheds important lights on DNA methylation evolution and function.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adr2222","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical experiments of waves generated by submerged steam eruptions with applications to volcanic tsunamis 水下蒸汽喷发产生波浪的物理实验及火山海啸的应用

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adk6208

Yaxiong Shen, Colin N. Whittaker, Emily M. Lane, James D. L. White, William Power

{"title":"Physical experiments of waves generated by submerged steam eruptions with applications to volcanic tsunamis","authors":"Yaxiong Shen, Colin N. Whittaker, Emily M. Lane, James D. L. White, William Power","doi":"10.1126/sciadv.adk6208","DOIUrl":"10.1126/sciadv.adk6208","url":null,"abstract":"<div >The tsunamigenic potential of underwater volcanic eruptions is not well understood, even though eruption-generated tsunamis can be devastating. To address how erupted steam bursts from underwater volcanoes generate tsunamis, we present the experiments, using pressurized steam injected vertically into a water tank. Results over various eruption conditions identify three eruption regimes, namely, shallow-, intermediate-, and deep-water eruptions, according to the combined effects of water depths, source strengths, and source durations. The transition between shallow and intermediate eruptions is characterized by critical depths maximizing tsunami wave heights, while the transition between intermediate and deep eruptions is characterized by containment depths inhibiting surface disturbances. Water depth and source intensity are the dominant factors controlling maximum wave amplitudes, more so than aspects of jet duration and condensation. These experiments and supporting dimensional analysis improve our understanding of how underwater volcanic eruptions form tsunamis, while also providing a complete dataset for advancing tsunami generation models.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adk6208","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of electrochemically accessible iridium oxide surface area with mercury underpotential deposition 利用汞欠电位沉积量化电化学可触及的氧化铱表面积

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adp8911

Jane Edgington, Sejal Vispute, Ruihan Li, Adrien Deberghes, Linsey C. Seitz

{"title":"Quantification of electrochemically accessible iridium oxide surface area with mercury underpotential deposition","authors":"Jane Edgington, Sejal Vispute, Ruihan Li, Adrien Deberghes, Linsey C. Seitz","doi":"10.1126/sciadv.adp8911","DOIUrl":"10.1126/sciadv.adp8911","url":null,"abstract":"<div >Research drives development of sustainable electrocatalytic technologies, but efforts are hindered by inconsistent reporting of advances in catalytic performance. Iridium-based oxide catalysts are widely studied for electrocatalytic technologies, particularly for the oxygen evolution reaction (OER) for proton exchange membrane water electrolysis, but insufficient techniques for quantifying electrochemically accessible iridium active sites impede accurate assessment of intrinsic activity improvements. We develop mercury underpotential deposition and stripping as a reversible electrochemical adsorption process to robustly quantify iridium sites and consistently normalize OER performance of benchmark IrO<i><sub>x</sub></i> electrodes to a single intrinsic activity curve, where other commonly used normalization methods cannot. Through rigorous deconvolution of mercury redox and reproportionation reactions, we extract net monolayer deposition and stripping of mercury on iridium sites throughout testing using a rotating ring disk electrode. This technique is a transformative method to standardize OER performance across a wide range of iridium-based materials and quantify electrochemical iridium active sites.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adp8911","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A disease resistance protein triggers oligomerization of its NLR helper into a hexameric resistosome to mediate innate immunity 抗病蛋白触发其 NLR 辅助蛋白寡聚成一个六聚体抗病基因组，从而介导先天性免疫

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adr2594

Jogi Madhuprakash, AmirAli Toghani, Mauricio P. Contreras, Andres Posbeyikian, Jake Richardson, Jiorgos Kourelis, Tolga O. Bozkurt, Michael W. Webster, Sophien Kamoun

{"title":"A disease resistance protein triggers oligomerization of its NLR helper into a hexameric resistosome to mediate innate immunity","authors":"Jogi Madhuprakash, AmirAli Toghani, Mauricio P. Contreras, Andres Posbeyikian, Jake Richardson, Jiorgos Kourelis, Tolga O. Bozkurt, Michael W. Webster, Sophien Kamoun","doi":"10.1126/sciadv.adr2594","DOIUrl":"10.1126/sciadv.adr2594","url":null,"abstract":"<div >NRCs are essential helper NLR (nucleotide-binding domain and leucine-rich repeat) proteins that execute immune responses triggered by sensor NLRs. The resting state of NbNRC2 was recently shown to be a homodimer, but the sensor-activated state remains unclear. Using cryo-EM, we determined the structure of sensor-activated NbNRC2, which forms a hexameric inflammasome-like resistosome. Mutagenesis of the oligomerization interface abolished immune signaling, confirming the functional significance of the NbNRC2 resistosome. Comparative structural analyses between the resting state homodimer and sensor-activated homohexamer revealed substantial rearrangements, providing insights into NLR activation mechanisms. Furthermore, structural comparisons between NbNRC2 hexamer and previously reported CC-NLR pentameric assemblies revealed features allowing an additional protomer integration. Using the NbNRC2 hexamer structure, we assessed the recently released AlphaFold 3 for predicting activated CC-NLR oligomers, revealing high-confidence modeling of NbNRC2 and other CC-NLR amino-terminal α1 helices, a region proven difficult to resolve structurally. Overall, our work sheds light on NLR activation mechanisms and expands understanding of NLR structural diversity.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adr2594","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-molecule profiling of per- and polyfluoroalkyl substances by cyclodextrin mediated host-guest interactions within a biological nanopore 在生物纳米孔中通过环糊精介导的主客体相互作用对全氟化烷基和多氟化烷基物质进行单分子分析

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adp8134

Xiaojun Wei, Aditya Choudhary, Leon Y. Wang, Lixing Yang, Mark J. Uline, Mario Tagliazucchi, Qian Wang, Dmitry Bedrov, Chang Liu

{"title":"Single-molecule profiling of per- and polyfluoroalkyl substances by cyclodextrin mediated host-guest interactions within a biological nanopore","authors":"Xiaojun Wei, Aditya Choudhary, Leon Y. Wang, Lixing Yang, Mark J. Uline, Mario Tagliazucchi, Qian Wang, Dmitry Bedrov, Chang Liu","doi":"10.1126/sciadv.adp8134","DOIUrl":"10.1126/sciadv.adp8134","url":null,"abstract":"<div >Biological nanopores are increasingly used in molecular sensing due to their single-molecule sensitivity. The detection of per- and polyfluoroalkyl substances (PFAS) like perfluorooctanoic acid and perfluorooctane sulfonic acid is critical due to their environmental prevalence and toxicity. Here, we investigate selective interactions between PFAS and four cyclodextrin (CD) variants (α-, β-, γ-, and 2-hydroxypropyl-γ-CD) within an α-hemolysin nanopore. We demonstrate that PFAS molecules can be electrochemically sensed by interacting with a γ-CD in a nanopore. Using HP-γ-CDs with increased steric resistance, we can identify homologs of the perfluoroalkyl carboxylic acid and the perfluoroalkyl sulfonic acid families and detect common PFAS in drinking water at 0.4 to 2 parts per million levels, which are further lowered to 400 parts per trillion by sample preconcentration. Molecular dynamics simulations reveal the underlying chemical mechanism of PFAS-CD interactions. These insights pave the way toward nanopore-based in situ detection with promises in environmental protection against PFAS pollution.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adp8134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness 以大脑为基础预测常见精神病的认知功能，具有普遍性和可复制性

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adn1862

Sidhant Chopra, Elvisha Dhamala, Connor Lawhead, Jocelyn A. Ricard, Edwina R. Orchard, Lijun An, Pansheng Chen, Naren Wulan, Poornima Kumar, Arielle Rubenstein, Julia Moses, Lia Chen, Priscila Levi, Alexander Holmes, Kevin Aquino, Alex Fornito, Ilan Harpaz-Rotem, Laura T. Germine, Justin T. Baker, B. T. Thomas Yeo, Avram J. Holmes

{"title":"Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness","authors":"Sidhant Chopra, Elvisha Dhamala, Connor Lawhead, Jocelyn A. Ricard, Edwina R. Orchard, Lijun An, Pansheng Chen, Naren Wulan, Poornima Kumar, Arielle Rubenstein, Julia Moses, Lia Chen, Priscila Levi, Alexander Holmes, Kevin Aquino, Alex Fornito, Ilan Harpaz-Rotem, Laura T. Germine, Justin T. Baker, B. T. Thomas Yeo, Avram J. Holmes","doi":"10.1126/sciadv.adn1862","DOIUrl":"10.1126/sciadv.adn1862","url":null,"abstract":"<div >A primary aim of computational psychiatry is to establish predictive models linking individual differences in brain functioning with symptoms. In particular, cognitive impairments are transdiagnostic, treatment resistant, and associated with poor outcomes. Recent work suggests that thousands of participants may be necessary for the accurate and reliable prediction of cognition, questioning the utility of most patient collection efforts. Here, using a transfer learning framework, we train a model on functional neuroimaging data from the UK Biobank to predict cognitive functioning in three transdiagnostic samples (ns = 101 to 224). We demonstrate prediction performance in all three samples comparable to that reported in larger prediction studies and a boost of up to 116% relative to classical models trained directly in the smaller samples. Critically, the model generalizes across datasets, maintaining performance when trained and tested across independent samples. This work establishes that predictive models derived in large population-level datasets can boost the prediction of cognition across clinical studies.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adn1862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-speed odor sensing using miniaturized electronic nose 利用微型电子鼻高速感应气味

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-06 DOI: 10.1126/sciadv.adp1764

Nik Dennler, Damien Drix, Tom P. A. Warner, Shavika Rastogi, Cecilia Della Casa, Tobias Ackels, Andreas T. Schaefer, André van Schaik, Michael Schmuker

{"title":"High-speed odor sensing using miniaturized electronic nose","authors":"Nik Dennler, Damien Drix, Tom P. A. Warner, Shavika Rastogi, Cecilia Della Casa, Tobias Ackels, Andreas T. Schaefer, André van Schaik, Michael Schmuker","doi":"10.1126/sciadv.adp1764","DOIUrl":"10.1126/sciadv.adp1764","url":null,"abstract":"<div >Animals have evolved to rapidly detect and recognize brief and intermittent encounters with odor packages, exhibiting recognition capabilities within milliseconds. Artificial olfaction has faced challenges in achieving comparable results—existing solutions are either slow; or bulky, expensive, and power-intensive—limiting applicability in real-world scenarios for mobile robotics. Here, we introduce a miniaturized high-speed electronic nose, characterized by high-bandwidth sensor readouts, tightly controlled sensing parameters, and powerful algorithms. The system is evaluated on a high-fidelity odor delivery benchmark. We showcase successful classification of tens-of-millisecond odor pulses and demonstrate temporal pattern encoding of stimuli switching with up to 60 hertz. Those timescales are unprecedented in miniaturized low-power settings and demonstrably exceed the performance observed in mice. It is now possible to match the temporal resolution of animal olfaction in robotic systems. This will allow for addressing challenges in environmental and industrial monitoring, security, neuroscience, and beyond.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adp1764","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142588808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0