Science Advances最新文献_第7页

Neurons derived from NeuroD1-expressing astrocytes transition through transit-amplifying intermediates but lack functional maturity 来自表达neurod1的星形胶质细胞的神经元通过转运扩增中间体转变，但缺乏功能成熟

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adw9296

Fangbing Chen, Xi Liu, Xiaowen Zhong, Xiaoqing Chen, Eva Nicholson, Kaiyi Liu, Huiyao Chen, Yifeng Lin, Yousheng Shu, Wenhao Zhou, Carol J. Schuurmans, Q. Richard Lu

{"title":"Neurons derived from NeuroD1-expressing astrocytes transition through transit-amplifying intermediates but lack functional maturity","authors":"Fangbing Chen, Xi Liu, Xiaowen Zhong, Xiaoqing Chen, Eva Nicholson, Kaiyi Liu, Huiyao Chen, Yifeng Lin, Yousheng Shu, Wenhao Zhou, Carol J. Schuurmans, Q. Richard Lu","doi":"10.1126/sciadv.adw9296","DOIUrl":"10.1126/sciadv.adw9296","url":null,"abstract":"<div >In vivo conversion of nonneuronal cells into neurons is a proposed strategy to replace neurons lost to CNS injury or disease. Glia-to-neuron trans-differentiation by viral vector–mediated GFAP mini-promoter–driven NeuroD1 remains hotly debated. Developing inducible, lineage-traceable transgenic mice, we find that astrocyte-to-neuron conversion is restricted to a specific time window within the lesion core of injured spinal cord and brain. Spatiotemporal lineage-mapping combined with single-cell transcriptomics reveals that ectopic NeuroD1 induces astrocyte-to-neuron conversion specifically in lesion cores via transit-amplifying OLIG2<sup>+</sup> progenitors during early injury phase, but not in late phases or in nonreactive astrocytes. Neither a loss-of-function NeuroD1 mutant nor stemness-reprogramming factor SOX2 induces astrocyte-to-neuron conversion. However, contrary to previous reports, the neuronal-like cells generated by NeuroD1 lack mature neuroelectrical properties, limiting their functional integration into neural circuits. Together, our findings establish a spatiotemporal framework for NeuroD1-driven glia-to-neuron conversion, revealing a mechanistic shift from direct astrocyte conversion toward transit-amplifying intermediates and highlighting the functional immaturity of NeuroD1-converted neurons.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adw9296","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrically controlled heat transport in graphite films via reversible ionic liquid intercalation 可逆离子液体插入石墨薄膜的电控热传递

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adw8588

Pietro Steiner, Saqeeb Adnan, M. Said Ergoktas, Julien Barrier, Xiaoxiao Yu, Vicente Orts, Gokhan Bakan, Jonathan Aze, Yury Malevich, Kaiyuan Wang, Pietro Cataldi, Mark Bissett, Sinan Balci, Sefik Suzer, Marat Khafizov, Coskun Kocabas

{"title":"Electrically controlled heat transport in graphite films via reversible ionic liquid intercalation","authors":"Pietro Steiner, Saqeeb Adnan, M. Said Ergoktas, Julien Barrier, Xiaoxiao Yu, Vicente Orts, Gokhan Bakan, Jonathan Aze, Yury Malevich, Kaiyuan Wang, Pietro Cataldi, Mark Bissett, Sinan Balci, Sefik Suzer, Marat Khafizov, Coskun Kocabas","doi":"10.1126/sciadv.adw8588","DOIUrl":"10.1126/sciadv.adw8588","url":null,"abstract":"<div >The ability to control heat transport with electrical signals has been an outstanding challenge due to the lack of efficient electrothermal materials. Previous attempts have mainly concentrated on low–thermal conductivity materials and encountered various problems such as narrow dynamic range and modest on/off ratios. Here, using high–thermal conductivity graphite films, we demonstrate an electrothermal switch enabling electrically tunable heat flow at the device level. The device uses reversible electro-intercalation of ions to modulate the in-plane thermal conductivity of graphite film by more than 13-fold via tunable phonon scattering, enabling observable modulation of the thermal conductivity at the device level. We anticipate that our results could provide a realistic pathway for adaptive thermal transport, enabling electrically driven thermal devices that would find a broad spectrum of applications in aerospace and microelectronics.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adw8588","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiation with reproductive isolation in the near-absence of phylogenetic signal 在几乎没有系统发育信号的情况下与生殖隔离的辐射

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adt0973

Martin Helmkampf, Floriane Coulmance, Melanie J. Heckwolf, Arturo Acero P., Alice Balard, Iliana Bista, Omar Dominguez Dominguez, Paul B. Frandsen, Montserrat Torres-Oliva, Aintzane Santaquiteria, Jose Tavera, Benjamin C. Victor, D. Ross Robertson, Ricardo Betancur-R., W. Owen McMillan, Oscar Puebla

{"title":"Radiation with reproductive isolation in the near-absence of phylogenetic signal","authors":"Martin Helmkampf, Floriane Coulmance, Melanie J. Heckwolf, Arturo Acero P., Alice Balard, Iliana Bista, Omar Dominguez Dominguez, Paul B. Frandsen, Montserrat Torres-Oliva, Aintzane Santaquiteria, Jose Tavera, Benjamin C. Victor, D. Ross Robertson, Ricardo Betancur-R., W. Owen McMillan, Oscar Puebla","doi":"10.1126/sciadv.adt0973","DOIUrl":"10.1126/sciadv.adt0973","url":null,"abstract":"<div >According to the genic view, species are characterized by the genes that underlie functional divergence. Here, we take a phylogenomic approach to assess this view at the scale of a whole radiation. The hamlets (<i>Hypoplectrus</i> spp.) represent a recent radiation of reef fishes from the Greater Caribbean that are reproductively isolated through assortative mating. A total of 335 genomes from 15 locations revealed a single well-supported phylogenetic split among species, with a large share of the radiation unresolved. The polytomic nature of the hamlet radiation is extreme compared to other recent radiations such as Lake Victoria cichlids. At the gene-tree level, we identified just one genomic region, centered around the <i>casz1</i> transcription factor, with a topology that reflects species differences. These results show that phenotypic diversification and reproductive isolation—two major attributes of species—may unfold in the near-absence of phylogenetic signal, both genome-wide and at the gene-tree level.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adt0973","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration HAUS7作为DOCK3结合伙伴在促进轴突再生中的作用

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adq7105

Naoki Kiyota, Youichi Shinozaki, Xiaoli Guo, Atsuko Kimura, Kazuto Kawamura, Euido Nishijima, Sari Honda, Chikako Harada, Toru Nakazawa, Kazuhiko Namekata, Takayuki Harada

{"title":"Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration","authors":"Naoki Kiyota, Youichi Shinozaki, Xiaoli Guo, Atsuko Kimura, Kazuto Kawamura, Euido Nishijima, Sari Honda, Chikako Harada, Toru Nakazawa, Kazuhiko Namekata, Takayuki Harada","doi":"10.1126/sciadv.adq7105","DOIUrl":"10.1126/sciadv.adq7105","url":null,"abstract":"<div >The molecular mechanisms involved in reconstructing the eye-to-brain connection and functional recovery following optic nerve damage remain unclear. This study revealed that HAUS augmin-like complex subunit 7 (HAUS7) is a molecule that binds to dedicator of cytokinesis 3 (DOCK3), a regulator of neurotrophic factor signaling and axon regeneration. We observed a distribution pattern of HAUS7 expression, suggesting that neuronal HAUS7 is transported from the cell body to the growth cone under the control of DOCK3. In addition, phosphorylation of DOCK3 at Y562 by tropomyosin receptor kinase B signaling leads to the dissociation of HAUS7, which is considered an important step for microtubule assembly. Deletion of <i>Haus7</i> in mice significantly reduced microtubule formation and axon regeneration following optic nerve crush (ONC). Transcriptome analysis suggested that HAUS7 levels decrease in glaucoma and after the ONC, while retinal ganglion cells actively regenerating their axons express high levels of HAUS7. In summary, HAUS7 is a binding partner of DOCK3 necessary for axon elongation.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq7105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of metal anode reversibility with solvation chemistry and interfacial electron transfer in aqueous electrolytes 金属阳极可逆性与水溶液中溶剂化化学和界面电子转移的关系

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adx8413

Yunpei Zhu, Simil Thomas, Tairan Wang, Xianrong Guo, Yizhou Wang, Chen Liu, S. Mani Sarathy, Xixiang Zhang, Osman M. Bakr, Omar F. Mohammed, Husam N. Alshareef

{"title":"Correlation of metal anode reversibility with solvation chemistry and interfacial electron transfer in aqueous electrolytes","authors":"Yunpei Zhu, Simil Thomas, Tairan Wang, Xianrong Guo, Yizhou Wang, Chen Liu, S. Mani Sarathy, Xixiang Zhang, Osman M. Bakr, Omar F. Mohammed, Husam N. Alshareef","doi":"10.1126/sciadv.adx8413","DOIUrl":"10.1126/sciadv.adx8413","url":null,"abstract":"<div >Reversible electrodeposition of metals is a crucial route to developing high-energy and rechargeable batteries. However, uncontrolled and nonplanar morphological evolution and parasitic reactions at the metal anodes are fundamental barriers to realizing full reversibility. Here, using aqueous electrochemistry as a probe, we develop multiscale characterization tools that can precisely determine the root cause of these morphological instabilities and parasitic reactions. Our analysis indicates that these issues are fundamentally from the free water molecules in aqueous electrolytes, leading to low reversibility of metal anodes. We therefore demonstrate a straightforward and effective strategy, based on modulating the solute anions in aqueous electrolytes, to suppress free water molecule concentration in conventional aqueous electrolytes. A proof of concept is demonstrated using a Zn metal anode, which shows unprecedented reversibility and stability in conventional aqueous electrolytes with structure-making anions under a harsh condition of 10 milliampere hours per square centimeter. This work unlocks an alternative angle to develop sustainable electrolytes for cost-efficient, practical battery chemistries.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adx8413","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum for the Research Article “Gradient double-twisted Bouligand structural design for high impact resistance over a wide range of loading velocities” by S.-M. Wen et al. 研究文章《在大加载速度范围内抗高冲击的梯度双扭布利甘结构设计》的勘误。温等人。

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.aea0930

引用次数: 0

Thermoresponsive antioxidant metal-free carbon nanodot hydrogel: An effective therapeutic approach for ocular surface disease 热响应性抗氧化无金属碳纳米点水凝胶：眼表疾病的有效治疗方法

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adt8775

Mei Yang, Xin Chen, Zhongxing Chen, Nan Zhao, Zhenhai Zeng, Xiaomin Huang, Zheng Li, Jiawei Li, Guoli Zhao, Manli Deng, Zhilin Zou, Hongxian Pan, Aodong Chen, Tingting Chen, Yue Wu, Xueyu Fu, Qimanguli Saiding, Na Kong, Wei Tao, Xingtao Zhou, Jinhai Huang

{"title":"Thermoresponsive antioxidant metal-free carbon nanodot hydrogel: An effective therapeutic approach for ocular surface disease","authors":"Mei Yang, Xin Chen, Zhongxing Chen, Nan Zhao, Zhenhai Zeng, Xiaomin Huang, Zheng Li, Jiawei Li, Guoli Zhao, Manli Deng, Zhilin Zou, Hongxian Pan, Aodong Chen, Tingting Chen, Yue Wu, Xueyu Fu, Qimanguli Saiding, Na Kong, Wei Tao, Xingtao Zhou, Jinhai Huang","doi":"10.1126/sciadv.adt8775","DOIUrl":"10.1126/sciadv.adt8775","url":null,"abstract":"<div >Oxidative stress, an imbalance between the body’s oxidative and antioxidant systems, contributes markedly to the development of numerous ocular surface diseases, particularly dry eye disease (DED). Effective elimination or reduction of reactive oxygen species (ROS) can halt disease progression and alleviate symptoms. This study presents an innovative thermoresponsive, metal-free carbon nanodot (CD) hydrogel, termed F-CD hydrogel, which exhibits potent neutralization capabilities against multiple free radicals, including OH·, O<sub>2</sub><sup>−</sup>·, and ·DPPH. This hydrogel demonstrates remarkable antioxidant, anti-inflammatory, and antiapoptotic capacity, effectively relieving DED symptoms by eliminating ROS at their source. Furthermore, its thermosensitive characteristics enhance the adherence of CDs to the ocular surface. In mouse models of DED, the F-CD hydrogel accelerates epithelial repair, thickens the corneal epithelium, promotes tear secretion, and boosts goblet cell count by up-regulating protective genes while suppressing those promoting apoptosis and oxidative stress. Coupled with its excellent biocompatibility and reduced administration frequency and treatment duration, the F-CD hydrogel emerges as a promising therapeutic approach for DED.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adt8775","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neanderthals, hypercarnivores, and maggots: Insights from stable nitrogen isotopes 尼安德特人、超级食肉动物和蛆：来自稳定氮同位素的见解

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-25 DOI: 10.1126/sciadv.adt7466

Melanie M. Beasley, Julie J. Lesnik, John D. Speth

{"title":"Neanderthals, hypercarnivores, and maggots: Insights from stable nitrogen isotopes","authors":"Melanie M. Beasley, Julie J. Lesnik, John D. Speth","doi":"10.1126/sciadv.adt7466","DOIUrl":"10.1126/sciadv.adt7466","url":null,"abstract":"<div >Reconstructions of Eurasian Neanderthal diets based on stable nitrogen isotope ratios (δ<sup>15</sup>N) typically place hominins at the top of the food web, together with, or above, hypercarnivores, such as lions and wolves. We suggest that these high δ<sup>15</sup>N values may, in part, reflect the regular consumption of <sup>15</sup>N-enriched fly larvae (maggots) occurring in stored animal foods. The ethnohistoric record contains countless examples of Indigenous peoples routinely consuming putrefied animal foods with maggots. Here, we report the results of δ<sup>15</sup>N bulk analyses of fly larvae of three families (Diptera: Brachycera: Calliphoridae, Piophilidae, and Stratiomyidae) collected from putrefying carcasses. Putrefaction led to modest changes in the initial muscle tissue δ<sup>15</sup>N values that ranged from −0.6 to 7.7‰. Much greater δ<sup>15</sup>N values ranging from 5.4 to 43.2‰ were observed in the fly larvae associated with putrefaction. We suggest that frequent consumption of animal foods laced with maggots should be considered as a contributor to the high δ<sup>15</sup>N values observed in Late Pleistocene hominins.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adt7466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multienergy x-ray detection and imaging enabled by working voltage regulating unipolar carrier collection in perovskite detectors 在钙钛矿探测器中通过工作电压调节单极载流子收集实现多能x射线探测和成像

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-23 DOI: 10.1126/sciadv.ads2995

Yuwei Li, Xin Wang, Yijing Ding, Jingda Zhao, Shilin Liu, Yubing Xu, Qi Cheng, Ziyu Wei, Damian Chinedu Onwudiwe, Byung Seong Bae, Mehmet Ertuğrul, Ying Zhu, Wenbo Ma, Yang (Michael) Yang, Wei Lei, Xiaobao Xu

{"title":"Multienergy x-ray detection and imaging enabled by working voltage regulating unipolar carrier collection in perovskite detectors","authors":"Yuwei Li, Xin Wang, Yijing Ding, Jingda Zhao, Shilin Liu, Yubing Xu, Qi Cheng, Ziyu Wei, Damian Chinedu Onwudiwe, Byung Seong Bae, Mehmet Ertuğrul, Ying Zhu, Wenbo Ma, Yang (Michael) Yang, Wei Lei, Xiaobao Xu","doi":"10.1126/sciadv.ads2995","DOIUrl":"10.1126/sciadv.ads2995","url":null,"abstract":"<div >Multienergy x-ray imaging can provide additional substance information beyond morphology in conventional energy-integration imaging. The predominant approach, single photon counting, sets stringent requirements on low x-ray flux and signal discrimination and prolongs imaging time. Here, we report on the design of unipolar n-i-n perovskite detectors for multienergy x-ray imaging. Systematic characterization validates electrons dominating carrier dynamics in detectors, and the distribution of generated electrons varies as x-ray energy along its penetrating direction, whereas working voltage can manipulate electron drift length, ensuring their selective collection for x-ray energy discrimination. Our multienergy imaging array adopts high-flux x-ray in a normal imaging system and realizes fast 4-energy-bins x-ray images. By introducing the σ(<i>E<sub>i</sub></i>)/σ(<i>E<sub>j</sub></i>)-related multienergy digital subtraction algorithm, the images successfully distinguish the substance of targets side by side or by stacking, representing a notable advancement over conventional energy-integration imaging technique.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ads2995","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Starfish-inspired tube feet for temporary and switchable underwater adhesion and transportation 海星启发的管脚，用于临时和可切换的水下粘附和运输

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2025-07-23 DOI: 10.1126/sciadv.adx3539

Hyemin Lee, Yerin Ryu, Yejin Oh, Chorong Kim, Yoonjin Lee, Hyewon Choi, Jaekyoung Kim, Ji Hoon Kim, Jiwan Kang, Keun Park, Kevin T. Turner, Shu Yang, Hyunsik Yoon

{"title":"Starfish-inspired tube feet for temporary and switchable underwater adhesion and transportation","authors":"Hyemin Lee, Yerin Ryu, Yejin Oh, Chorong Kim, Yoonjin Lee, Hyewon Choi, Jaekyoung Kim, Ji Hoon Kim, Jiwan Kang, Keun Park, Kevin T. Turner, Shu Yang, Hyunsik Yoon","doi":"10.1126/sciadv.adx3539","DOIUrl":"10.1126/sciadv.adx3539","url":null,"abstract":"<div >Temporary and reversible underwater adhesion is important for a number of robotic applications, including picking up objects, facilitating locomotion in confined environments, and attaching to surfaces during periods of observation. Here, we present a starfish-inspired tube foot composed of a soft hydrogel mouth and a rigid stem, fabricated by integrating two serially bonded cylindrical components with distinct mechanical properties. Upon swelling, the initially straight hydrogel cylinder undergoes a selective shape transformation into a soft, cupped pad that deforms to stretch and spread upon contact, enabling effective adhesion to target surfaces. During detachment, a vacuum is formed within the tube, leading to strong underwater adhesion. The artificial tube feet show high adhesion hysteresis, autonomous release by external stimuli, and immediate detachment by pneumatic actuation with integrated system. The temporary underwater adhesive inspired by the tube feet of starfish enables functionality in underwater robotics and is demonstrated through underwater manipulation of rocks.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 30","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adx3539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144684968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0