Science Advances最新文献_第7页

Interplay between noble gases and MOFs: Insights from 129Xe and 83Kr NMR spectroscopy 稀有气体和mof之间的相互作用：来自129 Xe和83 Kr核磁共振光谱的见解

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-08 DOI: 10.1126/sciadv.aea1857

Wanli Zhang, Vinicius Martins, Jeffrey Collins, Reza Moshrefi, Samantha Michelle Gateman, Victor V. Terskikh, Yining Huang

{"title":"Interplay between noble gases and MOFs: Insights from 129Xe and 83Kr NMR spectroscopy","authors":"Wanli Zhang, Vinicius Martins, Jeffrey Collins, Reza Moshrefi, Samantha Michelle Gateman, Victor V. Terskikh, Yining Huang","doi":"10.1126/sciadv.aea1857","DOIUrl":"10.1126/sciadv.aea1857","url":null,"abstract":"<div >Efficient separation and storage of radioactive noble gas isotopes [krypton-85 (<sup>85</sup>Kr) and xenon-131m/133/135 (<sup>131m/133/135</sup>Xe)] from off-gas during spent nuclear fuel reprocessing are vital for environmental protection and noble gas recovery. Metal-organic frameworks (MOFs) are promising adsorbents, yet atomic-level insights into Xe and Kr adsorption remain limited. Here, we report the first application of high-field solid-state <sup>83</sup>Kr nuclear magnetic resonance (NMR), alongside extensive <sup>129</sup>Xe NMR, to investigate gas adsorption in eight MOFs representing three design strategies: ultramicroporous one-dimensional–channel MOFs with pore sizes matching noble gas diameters, functionalized MOFs, and MOFs with open metal sites. Single-gas and coadsorption studies reveal distinct adsorption sites, guest-host interactions, and gas dynamics in each MOF. Most MOFs retain crystallinity after exposure to 60-kilogray γ radiation. Several radiation-sensitive MOFs exhibit enhanced stability in the presence of Xe, suggesting that Xe adsorption enhances framework stability and may broaden the range of MOFs usable under γ radiation in nuclear off-gas separation. These findings offer valuable molecular-level design insights.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 41","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.aea1857","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Substantially improved efficiency and selectivity of carbon dioxide reduction by superior hydrated electron in microdroplet 微滴中优越的水合电子显著提高了二氧化碳还原效率和选择性

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-08 DOI: 10.1126/sciadv.adx5714

Qiuyue Ge, Yangyang Liu, Wenbo You, Yumo Li, Wei Wang, Le Yang, Lifang Xie, Kejian Li, Licheng Wang, Minglu Ma, Runbo Wang, Jilun Wang, Tingting Huang, Tao Wang, Xuejun Ruan, Minbiao Ji, Liwu Zhang

{"title":"Substantially improved efficiency and selectivity of carbon dioxide reduction by superior hydrated electron in microdroplet","authors":"Qiuyue Ge, Yangyang Liu, Wenbo You, Yumo Li, Wei Wang, Le Yang, Lifang Xie, Kejian Li, Licheng Wang, Minglu Ma, Runbo Wang, Jilun Wang, Tingting Huang, Tao Wang, Xuejun Ruan, Minbiao Ji, Liwu Zhang","doi":"10.1126/sciadv.adx5714","DOIUrl":"10.1126/sciadv.adx5714","url":null,"abstract":"<div >The photochemical conversion of CO<sub>2</sub> into valuable fuels faces challenges of low efficiency and poor selectivity. Hydrated electrons (e<sub>aq</sub><sup>−</sup>), with their extremely negative reduction potential, are promising CO<sub>2</sub>-reducing agents, yet their short lifetime limits selectivity and high-energy-density product formation. Herein, we show that microdroplet interfaces with strong electric fields (10<sup>9</sup> volts per meter) substantially extend the lifespan of e<sub>aq</sub><sup>−</sup> generated from industrial sulfite pollutants (SO<sub>3</sub><sup>2−</sup>), lowering energy barriers in the CO<sub>2</sub> reduction reaction and enabling targeted product formation. The machine learning strategy identified microdroplet size as the key parameter controlling electric field strength, product yield, and selectivity. In our lab-based scaled-up system, microdroplets <10 micrometers improved performance by four to seven orders of magnitude over bulk-phase systems, achieving ~99% methanol selectivity. Strong interfacial electric fields stabilize intermediates and modulate carbon-oxygen bond lengths, directing pathways to high-value products. This approach enables sustainable CO<sub>2</sub> utilization via microdroplets, potentially producing fuels from waste.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 41","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adx5714","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CRISPR/Cas9-germline editing of Biomphalaria glabrata: A breakthrough in genetic modification of snails that transmit schistosomiasis CRISPR/ cas9基因编辑光螺：传播血吸虫病蜗牛基因改造的突破

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-08 DOI: 10.1126/sciadv.adx5889

Kouhei Oonuma, Reiko Kuroda, Takayuki Uchida, Si-Ming Zhang

{"title":"CRISPR/Cas9-germline editing of Biomphalaria glabrata: A breakthrough in genetic modification of snails that transmit schistosomiasis","authors":"Kouhei Oonuma, Reiko Kuroda, Takayuki Uchida, Si-Ming Zhang","doi":"10.1126/sciadv.adx5889","DOIUrl":"10.1126/sciadv.adx5889","url":null,"abstract":"<div >Human schistosomiasis remains one of the most devastating parasitic diseases worldwide, and the development of genetically modified vector snails has long been a goal in the field. Here, we report the successful creation of genetically modified <i>Biomphalaria glabrata</i>, an important intermediate host, using CRISPR/Cas9 gene editing. We targeted the <i>fibrinogen-related protein 3.1</i> (<i>FREP3.1</i>) gene, confirmed stable germline transmission of the mutated gene, and established two different homozygous <i>FREP3.1</i>-edited lines. Disruption of the <i>FREP 3.1</i> gene did not alter snail susceptibility to <i>Schistosoma mansoni</i> infection, possibly due to a limited role of <i>FREP3.1</i> in resistance or to functional redundancy and/or compensatory expression within the highly diverse <i>FREP</i> gene family. Our study demonstrates successful germline editing, effective ex ovo culture of decapsulated embryos, and the generation of viable, genetically modified <i>B. glabrata</i> snails, thereby establishing a foundation for future genetic strategies to control schistosomiasis.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 41","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adx5889","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phage lysis protein LysM acts as a wedge to block MurJ conformational changes 噬菌体裂解蛋白Lys M作为楔子阻断MurJ构象变化

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-08 DOI: 10.1126/sciadv.ady8083

Hidetaka Kohga, Napathip Lertpreedakorn, Ryoji Miyazaki, Sixian Wu, Kaito Hosoda, Hiroyuki Tanaka, Yutaro S. Takahashi, Kunihito Yoshikaie, Yutetsu Kuruma, Hideki Shigematsu, Takaharu Mori, Tomoya Tsukazaki

{"title":"Phage lysis protein LysM acts as a wedge to block MurJ conformational changes","authors":"Hidetaka Kohga, Napathip Lertpreedakorn, Ryoji Miyazaki, Sixian Wu, Kaito Hosoda, Hiroyuki Tanaka, Yutaro S. Takahashi, Kunihito Yoshikaie, Yutetsu Kuruma, Hideki Shigematsu, Takaharu Mori, Tomoya Tsukazaki","doi":"10.1126/sciadv.ady8083","DOIUrl":"10.1126/sciadv.ady8083","url":null,"abstract":"<div >Many antibiotics target essential cellular processes. To combat multidrug-resistant bacteria, new antibacterial strategies are needed. In the peptidoglycan biogenesis pathway in <i>Escherichia coli</i>, MurJ, the lipid II flippase, is an essential membrane protein. The 37-residue protein M from the <i>Levivirus</i> phage, known as Lys<sup>M</sup> or Sgl<sup>M</sup>, targets MurJ and induces cell lysis; however, its molecular mechanism remains unclear. Here, we present the cryo-EM structure of the MurJ/Lys<sup>M</sup> (JM) complex at 3.09-angstrom resolution, revealing that Lys<sup>M</sup> interacts with the crevasse between TM2 and TM7 of MurJ, locking MurJ in an outward-facing conformation, with Lys<sup>M</sup> acting like a wedge. Alanine-scanning mutagenesis and pull-down assays revealed key residues responsible for Lys<sup>M</sup> function, and molecular dynamics simulations showed that Lys<sup>M</sup> stabilizes MurJ’s outward-facing state. These findings demonstrate an unprecedented phage-derived mechanism for blocking lipid II transport, providing a structural framework for designing MurJ-targeted antimicrobial agents.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 41","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ady8083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Conformal zwitterionic polymer nanofilms and lithium batteries 共形两性离子聚合物纳米膜与锂电池

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-08 DOI: 10.1126/sciadv.ady4460

Shuo Jin, Pengyu Chen, Shifeng Hong, Haonian Shu, Xiaosi Gao, Ziang Gao, Samuel Baffour, Mingjia Fang, Yong Lak Joo, Rong Yang, Lynden A. Archer

{"title":"Conformal zwitterionic polymer nanofilms and lithium batteries","authors":"Shuo Jin, Pengyu Chen, Shifeng Hong, Haonian Shu, Xiaosi Gao, Ziang Gao, Samuel Baffour, Mingjia Fang, Yong Lak Joo, Rong Yang, Lynden A. Archer","doi":"10.1126/sciadv.ady4460","DOIUrl":"10.1126/sciadv.ady4460","url":null,"abstract":"<div >Scalable synthesis of electrochemically inert nanofilms with precise spatial and compositional control enables rational design of solid-electrolyte interphases (SEIs) in rechargeable batteries. Ion and molecule transport through SEIs largely determines the cycling stability of high-energy rechargeable metal and metal-ion batteries, where electroreduction during charging often occurs beyond electrolyte stability limits. We report nanometer-thick gradient zwitterionic polymer (G-ZWP) interphases, synthesized via a scalable solvent-free method, to regulate transport and electroreduction kinetics at Li-metal anodes, achieving stable cycling. The synthesis combines initiated chemical vapor deposition and diffusion-limited vapor derivatization to form a zwitterionic top layer with high ionic conductivity and an inner covalently cross-linked layer blocking solvent access while remaining stable at reducing potentials. Cu substrates with G-ZWP interphases show >2000-hour cycling at 1 milliampere per square centimeter [6 milliampere hours per square centimeter (mA·hour/cm<sup>2</sup>)]. The interphases also enable long-term cycling of Li batteries (N/P = 0 to 2.5) and Li–dry-air batteries (10 mA·hour/cm<sup>2</sup>) and stabilize Na/Zn electrodeposition.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 41","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ady4460","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative and systematic behavioral profiling reveals social complexity in eusocial naked mole-rats 定量和系统的行为分析揭示了社会性裸鼹鼠的社会复杂性

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-08 DOI: 10.1126/sciadv.ady0481

Masanori Yamakawa, Takahiro Ezaki, Akiyuki Watarai, Nobuyuki Kutsukake, Kyoko Miura, Teruhiro Okuyama

{"title":"Quantitative and systematic behavioral profiling reveals social complexity in eusocial naked mole-rats","authors":"Masanori Yamakawa, Takahiro Ezaki, Akiyuki Watarai, Nobuyuki Kutsukake, Kyoko Miura, Teruhiro Okuyama","doi":"10.1126/sciadv.ady0481","DOIUrl":"10.1126/sciadv.ady0481","url":null,"abstract":"<div >In highly organized animal societies, individual behavioral differences and close social relationships are crucial for group success and cohesion. However, in naked mole-rats, a eusocial mammal, these factors remain poorly understood because monitoring all colony members simultaneously is challenging. We developed an automated radio frequency identification (RFID) tracking system to continuously collect behavioral data from entire colonies, monitoring 102 individuals from five colonies for 30 days. Based on behavioral parameters, we statistically identified distinct behavioral phenotypes, comprising one cluster for breeders and six clusters for nonbreeders. Breeders formed strong social bonds, consistently remaining close in activity rhythm synchrony, spatial proximity, and directional following. In contrast, nonbreeders exhibited behavioral heterogeneity according to their cluster: One cluster avoided other active nonbreeders, whereas another cluster attracted frequent following. Our study highlights social complexity in this eusocial mammal and establishes a robust platform for further investigations into naked mole-rat social dynamics.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 41","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ady0481","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum for the Research Article “Exendin-4 gene modification and microscaffold encapsulation promote self-persistence and antidiabetic activity of MSCs” by Y. Zhang et al. Zhang等人的研究文章“Exendin-4基因修饰和微支架包封促进MSCs的自我持久性和抗糖尿病活性”的勘误。

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-03 DOI: 10.1126/sciadv.aea8045

引用次数: 0

Comprehensive engineering of novel glycosyltransferase for efficient, donor-promiscuous, and regioselective glycosylation of flavonoids 用于黄酮类化合物高效、供体混杂和区域选择性糖基化的新型糖基转移酶的综合工程

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-03 DOI: 10.1126/sciadv.adu5064

Yang Lu, Lianghua Xie, Jiahong Xie, Gexin Liu, Jiaqi Fu, Luheng Zou, Qiu Lin, Yong Wang, Wei Chen

{"title":"Comprehensive engineering of novel glycosyltransferase for efficient, donor-promiscuous, and regioselective glycosylation of flavonoids","authors":"Yang Lu, Lianghua Xie, Jiahong Xie, Gexin Liu, Jiaqi Fu, Luheng Zou, Qiu Lin, Yong Wang, Wei Chen","doi":"10.1126/sciadv.adu5064","DOIUrl":"10.1126/sciadv.adu5064","url":null,"abstract":"<div >Flavonoid <i>O</i>-glycosylation, catalyzed by uridine diphosphate (UDP)–glycosyltransferases, is crucial for their therapeutic efficacy. However, most UDP-glycosyltransferases encounter three major limitations: low activity, poor regioselectivity, and restricted substrate availability, hindering their pharmaceutical applications. To address these challenges, we conducted protein engineering on a previously unidentified glycosyltransferase, UGT75AJ2, which had 3′,7-<i>O</i>-glycosylation capabilities. Our approach involved three strategies: (i) development of a tailored focused rational iterative site-specific mutagenesis strategy, augmented by virtual screening and iterative mutagenesis, to design mutant Mut4-1 (S367A/V274A/F82V/I132T) with a 128-fold enhancement in relative catalytic activity; (ii) enhancement of the enzyme’s compatibility with a broader spectrum of sugar donors achieved through structural-based engineering, yielding mutant S14G/F366H/S367G and demonstrating effective utilization of diverse donors; (iii) construction of a targeted mutant library to enhance regioselectivity by active site analysis, leading to mutants with high selectivity for targeted glycosylation sites. This comprehensive study tackles predominant challenges in UDP-glycosyltransferases protein engineering, providing innovative approaches and insights that enhance the development of flavonoid glycosides.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 40","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adu5064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-step separation of lithium from natural ores in seconds 在几秒钟内从天然矿石中一步分离锂

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-03 DOI: 10.1126/sciadv.ady6457

Shichen Xu, Justin Sharp, Alex Lathem, Qiming Liu, Lucas Eddy, Weiqiang Chen, Karla J. Silva, Shihui Chen, Bowen Li, Tengda Si, Jaeho Shin, Chi Hun Choi, Yimo Han, Kai Gong, Boris I. Yakobson, Yufeng Zhao, James M. Tour

{"title":"One-step separation of lithium from natural ores in seconds","authors":"Shichen Xu, Justin Sharp, Alex Lathem, Qiming Liu, Lucas Eddy, Weiqiang Chen, Karla J. Silva, Shihui Chen, Bowen Li, Tengda Si, Jaeho Shin, Chi Hun Choi, Yimo Han, Kai Gong, Boris I. Yakobson, Yufeng Zhao, James M. Tour","doi":"10.1126/sciadv.ady6457","DOIUrl":"10.1126/sciadv.ady6457","url":null,"abstract":"<div >Lithium (Li), the lowest-density metal, is an optimal element in most battery designs. With the increasing demand for Li, metallurgical techniques using excess acid leaching of mineral ores are common. However, these techniques are limited by multistep processes with adverse environmental impacts caused by secondary waste streams. Here, we show a one-step, acid-free, and alkali-free extraction process for Li from mineral ores with an initial Li content of only 4.8%. By applying flash Joule heating to α-spodumene under an atmosphere of Cl<sub>2</sub> (FJH-Cl<sub>2</sub>), LiCl immediately distills from the remaining nonvolatile aluminum and silicon oxides. LiCl with a 97% purity and 94% yield can be achieved, enormously reducing costs and waste emissions. Local processing with FJH-Cl<sub>2</sub> can markedly lessen the complexity and cost of obtaining Li, obviating remote mining and facilitating the world’s progression toward cleaner renewable energies, which also paves the way for extracting critical metals from other mineral ores.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 40","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ady6457","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced spectral purity of WSe2 quantum emitters via conformal organic adlayers 通过共形有机贴片提高wse2量子发射体的光谱纯度

IF 12.5 1区综合性期刊

Science Advances Pub Date : 2025-10-03 DOI: 10.1126/sciadv.ady7557

Riddhi Ananth, M. Iqbal Bakti Utama, David D. Xu, Albert F. Vong, Tumpa Sadhukhan, Hongfei Zeng, Rafael López-Arteaga, Wei Wang, Seok Daniel Namgung, S. Carin Gavin, Anushka Dasgupta, Yi Liang, Alina Bennett, Fateme Mahdikhany, Kenji Watanabe, Takashi Taniguchi, Vinod K. Sangwan, Chad A. Mirkin, Tobin J. Marks, Xuedan Ma, Nathaniel P. Stern, George C. Schatz, Emily A. Weiss, Mark C. Hersam

{"title":"Enhanced spectral purity of WSe2 quantum emitters via conformal organic adlayers","authors":"Riddhi Ananth, M. Iqbal Bakti Utama, David D. Xu, Albert F. Vong, Tumpa Sadhukhan, Hongfei Zeng, Rafael López-Arteaga, Wei Wang, Seok Daniel Namgung, S. Carin Gavin, Anushka Dasgupta, Yi Liang, Alina Bennett, Fateme Mahdikhany, Kenji Watanabe, Takashi Taniguchi, Vinod K. Sangwan, Chad A. Mirkin, Tobin J. Marks, Xuedan Ma, Nathaniel P. Stern, George C. Schatz, Emily A. Weiss, Mark C. Hersam","doi":"10.1126/sciadv.ady7557","DOIUrl":"10.1126/sciadv.ady7557","url":null,"abstract":"<div >Quantum emitters in solid-state materials are typically embedded in the bulk of their hosts, making their electronic transitions inaccessible to surface modification. In contrast, two-dimensional materials, with their all-surface nature, offer a platform for tuning quantum emitters via chemical functionalization. Because of its semiconducting properties that enable electrical addressability, monolayer WSe<sub>2</sub> is a promising candidate for quantum emission, although the complex interplay between point defects and the localized strain needed to activate quantum emission leads to poor spectral purity. Here, we demonstrate that functionalizing monolayer WSe<sub>2</sub> with conformal adlayers of 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) improves quantum emission spectral purity. Optical spectroscopy reveals that PTCDA functionalization lowers defect activation energies by 10 meV and induces a 30 nm redshift in quantum emission wavelength, while preserving the bright and dark exciton energies of monolayer WSe<sub>2</sub>. First-principles calculations corroborate these findings, thus providing molecular-level insight into the underlying mechanism of enhanced spectral purity.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 40","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ady7557","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0