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Parthenocissus-inspired soft climbing robots
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adt9284
Kecheng Qin, Wei Tang, Huaizhi Zong, Xinyu Guo, Huxiu Xu, Yiding Zhong, Yonghao Wang, Qincheng Sheng, Huayong Yang, Jun Zou
{"title":"Parthenocissus-inspired soft climbing robots","authors":"Kecheng Qin,&nbsp;Wei Tang,&nbsp;Huaizhi Zong,&nbsp;Xinyu Guo,&nbsp;Huxiu Xu,&nbsp;Yiding Zhong,&nbsp;Yonghao Wang,&nbsp;Qincheng Sheng,&nbsp;Huayong Yang,&nbsp;Jun Zou","doi":"10.1126/sciadv.adt9284","DOIUrl":"10.1126/sciadv.adt9284","url":null,"abstract":"<div >Climbing robots have attracted growing attention due to their mobility on vertical and nonplanar structural surfaces. However, the development of climbing robots capable of climbing on various complex surfaces remains elusive, especially on discontinuous surfaces. In nature, <i>Parthenocissus</i> climbs as it grows, having growing-climbing behaviors. Inspired by <i>Parthenocissus</i>, we propose a growing-climbing mechanism and report a soft climbing robot, which grows microstructured biofilms to enhance adhesion, similar to <i>Parthenocissus</i> growing suckers and adsorbing to the wall. The robot uses shape memory alloy contraction to achieve bending, similar to <i>Parthenocissus</i> using gelatinous fibers contraction to achieve hinge-like bending. In addition, to not damage the site, it can be fully contracted after completing tasks. The climbing robot can climb on various complex surfaces, especially discontinuous surfaces, verifying the effectiveness of <i>Parthenocissus</i>’ growing-climbing mechanism. The growing-climbing mechanism is a universal climbing robot paradigm, opening a door for complex surface climbing robots.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adt9284","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A millisecond integrated quantum memory for photonic qubits
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adu5264
Yu-Ping Liu, Zhong-Wen Ou, Tian-Xiang Zhu, Ming-Xu Su, Chao Liu, Yong-Jian Han, Zong-Quan Zhou, Chuan-Feng Li, Guang-Can Guo
{"title":"A millisecond integrated quantum memory for photonic qubits","authors":"Yu-Ping Liu,&nbsp;Zhong-Wen Ou,&nbsp;Tian-Xiang Zhu,&nbsp;Ming-Xu Su,&nbsp;Chao Liu,&nbsp;Yong-Jian Han,&nbsp;Zong-Quan Zhou,&nbsp;Chuan-Feng Li,&nbsp;Guang-Can Guo","doi":"10.1126/sciadv.adu5264","DOIUrl":"10.1126/sciadv.adu5264","url":null,"abstract":"<div >Quantum memories for light are essential building blocks for quantum repeaters and quantum networks. Integrated operations of quantum memories could enable scalable application with low-power consumption. However, the photonic quantum storage lifetime in integrated devices has so far been limited to tens of microseconds, falling short of the requirements for practical applications. Here, we demonstrate quantum storage of photonic qubits for 1.021 milliseconds based on a laser-written optical waveguide fabricated in a <sup>151</sup>Eu<sup>3+</sup>:Y<sub>2</sub>SiO<sub>5</sub> crystal. Spin dephasing of <sup>151</sup>Eu<sup>3+</sup> is mitigated through dynamical decoupling applied via on-chip electric waveguides, and we obtain a storage efficiency of 12.0 ± 0.5% at 1.021 milliseconds, which is a demonstration of integrated quantum memories that outperforms the efficiency of a simple fiber delay line. Such long-lived waveguide-based quantum memory could support applications in quantum repeaters, and further combination with critical magnetic fields could enable potential application as transportable quantum memories.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adu5264","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A memristor-based unified PUF and TRNG chip with a concealable ability for advanced edge security
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adr0112
Xueqi Li, Bohan Lin, Bin Gao, Yuyao Lu, Siyao Yang, Zhiqiang Su, Ting-Ying Shen, Jianshi Tang, He Qian, Huaqiang Wu
{"title":"A memristor-based unified PUF and TRNG chip with a concealable ability for advanced edge security","authors":"Xueqi Li,&nbsp;Bohan Lin,&nbsp;Bin Gao,&nbsp;Yuyao Lu,&nbsp;Siyao Yang,&nbsp;Zhiqiang Su,&nbsp;Ting-Ying Shen,&nbsp;Jianshi Tang,&nbsp;He Qian,&nbsp;Huaqiang Wu","doi":"10.1126/sciadv.adr0112","DOIUrl":"10.1126/sciadv.adr0112","url":null,"abstract":"<div >Security primitives ensure Internet of Things (IoT) security by generating stable keys from physically unclonable functions (PUFs) and unpredictable bitstreams from true random number generators (TRNGs). Considering the restricted resources on IoT motes, a promising design trend is to unify PUF and TRNG by sharing the same entropy source and multiplexing entropy extractor. Here, we report a unified PUF and TRNG chip based on a 28-nanometer embedded memristor with concealable ability. We use the memristor intrinsic FORMING condition variation and read current variation as entropy sources and design a compact on-chip entropy extractor that achieves a high throughput of 41.7 megabits per second with minimal area overhead of 0.291 MF<sup>2</sup>. To prevent PUF data leakage, we developed a concealment method, protecting data when idle and enabling recovery upon demand. Comprehensive testing shows the chip has excellent performance in randomness, reliability, lifetime, and stability, achieving a 3.82-fold throughput improvement over complementary metal-oxide semiconductor–based designs in authentication tasks.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adr0112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic high-throughput evaluation reveals FrCas9’s superior specificity and efficiency for therapeutic genome editing
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adu7334
Rui Tian, Xun Tian, Meiying Yang, Yuping Song, Tingting Zhao, Chaoyue Zhong, Wei Zhu, Ping Zhou, Zhiqiang Han, Zheng Hu
{"title":"Systematic high-throughput evaluation reveals FrCas9’s superior specificity and efficiency for therapeutic genome editing","authors":"Rui Tian,&nbsp;Xun Tian,&nbsp;Meiying Yang,&nbsp;Yuping Song,&nbsp;Tingting Zhao,&nbsp;Chaoyue Zhong,&nbsp;Wei Zhu,&nbsp;Ping Zhou,&nbsp;Zhiqiang Han,&nbsp;Zheng Hu","doi":"10.1126/sciadv.adu7334","DOIUrl":"10.1126/sciadv.adu7334","url":null,"abstract":"<div >CRISPR-Cas9 systems have revolutionized genome editing, but the off-target effects of Cas9 limit its use in clinical applications. Here, we systematically evaluate FrCas9, a variant from <i>Faecalibaculum rodentium</i>, for cell and gene therapy (CGT) applications and compare its performance to SpCas9 and OpenCRISPR-1. OpenCRISPR-1 is a CRISPR system synthesized de novo using large language models (LLMs) but has not yet undergone systematic characterization. Using AID-seq, Amplicon sequencing, and GUIDE-seq, we assessed the on-target activity and off-target profiles of these systems across multiple genomic loci. FrCas9 demonstrated higher on-target efficiency and substantially fewer off-target effects than SpCas9 and OpenCRISPR-1. Furthermore, TREX2 fusion with FrCas9 reduced large deletions and translocations, enhancing genomic stability. Through screening of 1903 sgRNAs targeting 21 CGT-relevant genes using sequential AID-seq, Amplicon sequencing, and GUIDE-seq analysis, we identified optimal sgRNAs for each gene. Our high-throughput screening platform highlights FrCas9, particularly in its TREX2-fused form, as a highly specific and efficient tool for precise therapeutic genome editing.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adu7334","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Programmable engineered bacteria as sustained-releasing antibody factory in situ for enhancing tumor immune checkpoint therapy
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adt7298
Xiao-Ting Xie, Meng Guan, Kai Cheng, Yong Li, Bin Zhang, Yi-Tong Zhou, Lin-Fang Tan, Peng-Shuo Dong, Si Chen, Bo Liu, Yuan-Di Zhao, Jin-Xuan Fan
{"title":"Programmable engineered bacteria as sustained-releasing antibody factory in situ for enhancing tumor immune checkpoint therapy","authors":"Xiao-Ting Xie,&nbsp;Meng Guan,&nbsp;Kai Cheng,&nbsp;Yong Li,&nbsp;Bin Zhang,&nbsp;Yi-Tong Zhou,&nbsp;Lin-Fang Tan,&nbsp;Peng-Shuo Dong,&nbsp;Si Chen,&nbsp;Bo Liu,&nbsp;Yuan-Di Zhao,&nbsp;Jin-Xuan Fan","doi":"10.1126/sciadv.adt7298","DOIUrl":"10.1126/sciadv.adt7298","url":null,"abstract":"<div >Tumor immune checkpoint therapy (ICT) aims to block immune escape signals between tumor and immune cells. However, low delivery efficiency of immune checkpoint inhibitors (ICIs), narrow single-target approach, and reduced responsiveness notably hinder clinical development of ICT. Here, we developed a nanoliposome-bacteria hybrid system that acts as an antibody (Ab) factory, enabling precise tumor targeting and macrophage activation in hypoxic environments. We reprogrammed attenuated <i>Escherichia coli</i> MG1655 to synthesize CD47 antibodies (aCD47) in response to hypoxic tumor microenvironments while surface conjugating with redox-responsive macrophage colony-stimulating factor-loaded liposomes. This system leverages bacterial tropism to enhance macrophage infiltration and polarization. The low oxygen levels trigger in situ aCD47 expression, blocking the “do not eat me” signal and boosting macrophage antitumor activity. In addition, macrophage antigen presentation activates CD8+CD3+ T cells, amplifying systemic antitumor immunity. Analysis of the gut microbiome shows reduced pathogenicity and improved intestinal tolerance with increased probiotics.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adt7298","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A synthetic genomics-based African swine fever virus engineering platform
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adu7670
Walter Fuchs, Nacyra Assad-Garcia, Hussein M. Abkallo, Yong Xue, Lauren M. Oldfield, Nadia Fedorova, Alexandra Hübner, Tonny Kabuuka, Katrin Pannhorst, Dirk Höper, Vishvanath Nene, Norberto Gonzalez-Juarbe, Lucilla Steinaa, Sanjay Vashee
{"title":"A synthetic genomics-based African swine fever virus engineering platform","authors":"Walter Fuchs,&nbsp;Nacyra Assad-Garcia,&nbsp;Hussein M. Abkallo,&nbsp;Yong Xue,&nbsp;Lauren M. Oldfield,&nbsp;Nadia Fedorova,&nbsp;Alexandra Hübner,&nbsp;Tonny Kabuuka,&nbsp;Katrin Pannhorst,&nbsp;Dirk Höper,&nbsp;Vishvanath Nene,&nbsp;Norberto Gonzalez-Juarbe,&nbsp;Lucilla Steinaa,&nbsp;Sanjay Vashee","doi":"10.1126/sciadv.adu7670","DOIUrl":"10.1126/sciadv.adu7670","url":null,"abstract":"<div >African swine fever (ASF) is a deadly viral disease in domestic pigs that has a large global economic impact for the swine industry. It is present in Africa, Europe, Asia, and in the Caribbean island of Hispaniola. There are no effective treatments or broadly licensed vaccines to prevent disease. Efforts to counteract ASF have been hampered because of the lack of convenient tools to engineer its etiological agent, ASF virus (ASFV), largely due to its large noninfectious genome. Here, we report the use of synthetic genomics methodology to develop a reverse genetics system for ASFV using a CRISPR-Cas9–inhibited self-helper virus to reconstitute live recombinant ASFV from synthetic genomes to rapidly generate a variety of combinatorial mutants of ASFV. The method will substantially facilitate the development of therapeutics or subunit and live-attenuated vaccines for ASF. This synthetic genomics-based approach has wide-ranging impact because it can be applied to rapidly develop reverse genetics tools for emerging viruses with noninfectious genomes.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adu7670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic antitumor immune response of doped yttria nanoscintillators under low-dose x-ray irradiation
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-26 DOI: 10.1126/sciadv.adr4008
Onur Sahin, Yuri Mackeyev, Geraldine V. Vijay, Soumyabrata Roy, Ashokkumar Meiyazhagan, Yasmin Zahra, Okan Tezcan, Valeria Gonzalez, Belal Abousaida, Holden R. Wagner, Pearl Fernandes, Riaz Mowzoon-Mogharrabi, Bhanu P. Venkatesulu, Cheng-En Hsieh, Joseph B. K. Kim, Subhiksha Raghuram, Xiang Zhang, Kristen A. Miller, Guanhui Gao, Pankaj K. Singh, Sang Hyun Cho, Rao V. L. Papineni, Pulickel M. Ajayan, Sunil Krishnan
{"title":"Systemic antitumor immune response of doped yttria nanoscintillators under low-dose x-ray irradiation","authors":"Onur Sahin,&nbsp;Yuri Mackeyev,&nbsp;Geraldine V. Vijay,&nbsp;Soumyabrata Roy,&nbsp;Ashokkumar Meiyazhagan,&nbsp;Yasmin Zahra,&nbsp;Okan Tezcan,&nbsp;Valeria Gonzalez,&nbsp;Belal Abousaida,&nbsp;Holden R. Wagner,&nbsp;Pearl Fernandes,&nbsp;Riaz Mowzoon-Mogharrabi,&nbsp;Bhanu P. Venkatesulu,&nbsp;Cheng-En Hsieh,&nbsp;Joseph B. K. Kim,&nbsp;Subhiksha Raghuram,&nbsp;Xiang Zhang,&nbsp;Kristen A. Miller,&nbsp;Guanhui Gao,&nbsp;Pankaj K. Singh,&nbsp;Sang Hyun Cho,&nbsp;Rao V. L. Papineni,&nbsp;Pulickel M. Ajayan,&nbsp;Sunil Krishnan","doi":"10.1126/sciadv.adr4008","DOIUrl":"10.1126/sciadv.adr4008","url":null,"abstract":"<div >Inadequate light penetration in tissues restricts photodynamic therapy to treating only superficial tumors. To enable x-ray–excited photodynamic therapy (XPDT) that targets deep-seated tumors, we synthesized a nanoscintillator-photosensitizer complex containing 5% Eu-doped Y<sub>2</sub>O<sub>3</sub> fluorescing at 611 nanometers and decorated with SiO<sub>2</sub> containing the scintillation-coupled photosensitizer methylene blue and a polyethylene glycol coating [PEGylated Y<sub>2</sub>O<sub>3</sub>:Eu@SiO<sub>2</sub>-methylene blue (pYSM)]. When irradiated, pYSMs generate singlet oxygen species in vitro, causing cytotoxicity with hallmarks of immunogenic cell death (calreticulin translocation to the cell membrane). Intravenously administered pYSMs home passively to pancreatic tumor xenografts and, upon 10 gray irradiation, cause significant tumor regression (<i>P</i> &lt; 0.01). On combining XPDT with anti-PD1 immunotherapy, a distant nonirradiated tumor also regresses via an increase in intratumoral activated CD8<sup>+</sup> cytotoxic T cells. Collectively, we advance a systemically delivered XPDT strategy that mediates an antitumor effect in both irradiated and nonirradiated (abscopal) tumors when coupled with immunotherapy, converting an immunologically “cold” tumor to an immunologically “hot” tumor.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 13","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adr4008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinct attentional characteristics of neurons with visual feature coding in the primate brain
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-21 DOI: 10.1126/sciadv.adq0332
Jie Zhang, Runnan Cao, Xiaocang Zhu, Huihui Zhou, Shuo Wang
{"title":"Distinct attentional characteristics of neurons with visual feature coding in the primate brain","authors":"Jie Zhang,&nbsp;Runnan Cao,&nbsp;Xiaocang Zhu,&nbsp;Huihui Zhou,&nbsp;Shuo Wang","doi":"10.1126/sciadv.adq0332","DOIUrl":"10.1126/sciadv.adq0332","url":null,"abstract":"<div >Visual attention and object recognition are two critical cognitive functions that shape our perception of the world. While these neural processes converge in the temporal cortex, the nature of their interactions remains largely unclear. Here, we systematically investigated the interplay between visual attention and stimulus feature coding by training macaques to perform a free-gaze visual search task with natural stimuli. Recording from a large number of units across multiple brain areas, we found that units exhibiting visual feature coding showed stronger attentional modulation of responses and spike–local field potential coherence than units without feature coding. Across brain areas, attention directed toward search targets enhanced the neuronal pattern separation of stimuli, with this enhancement more pronounced for units encoding visual features. Together, our results suggest a complex interplay between visual feature and attention coding in the primate brain, likely driven by interactions between brain areas engaged in these processes.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 12","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq0332","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143666263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultranarrow-linewidth wavelength-vortex metasurface holography
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-21 DOI: 10.1126/sciadv.adt9159
Weijia Meng, Johannes E. Fröch, Ke Cheng, Dapu Pi, Baoli Li, Arka Majumdar, Stefan A. Maier, Haoran Ren, Min Gu, Xinyuan Fang
{"title":"Ultranarrow-linewidth wavelength-vortex metasurface holography","authors":"Weijia Meng,&nbsp;Johannes E. Fröch,&nbsp;Ke Cheng,&nbsp;Dapu Pi,&nbsp;Baoli Li,&nbsp;Arka Majumdar,&nbsp;Stefan A. Maier,&nbsp;Haoran Ren,&nbsp;Min Gu,&nbsp;Xinyuan Fang","doi":"10.1126/sciadv.adt9159","DOIUrl":"10.1126/sciadv.adt9159","url":null,"abstract":"<div >Metasurface holograms harness multiple degrees of freedom of light to enhance information channel capacity. Traditionally, wavelength multiplexing holography with high-capacity information channel was only achievable through 3D volume holograms using Bragg diffraction. Here, we demonstrate ultranarrow-linewidth wavelength-vortex multiplexing holography in metasurface holograms. By applying elementary dispersion engineering, we develop a sparse <i>k</i>-vector–filtering aperture array in momentum space, enabling sharp wavelength selectivity combined with orbital angular momentum selectivity. Further leveraging transformer neural networks for the design of phase-only holograms, we showcase the reconstruction of up to 118 independent images from a single hologram, achieving a simulated ultranarrow linewidth of 2 nanometers within the visible range. We apply these developed metasurface holograms for holographic visual cryptography, attaining unprecedented security levels with an information rate over 2500 times higher than traditional methods. Our results open exciting avenues for the application of metasurface holograms in various fields, including 3D displays, holographic encryption, and optical artificial intelligence.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 12","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adt9159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143666300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distortion-free sampling of ultrabroadband terahertz electric fields by interfacial spin accumulation
IF 11.7 1区 综合性期刊
Science Advances Pub Date : 2025-03-21 DOI: 10.1126/sciadv.adq7741
Alexander L. Chekhov, Yannic Behovits, Julius J. F. Heitz, Maria-Andromachi Syskaki, Samridh Jaiswal, Oliver Gueckstock, Bruno R. Serrano, Amon Ruge, Jana Kredl, Martin Wolf, Markus Münzenberg, Gerhard Jakob, Mathias Kläui, Tom S. Seifert, Tobias Kampfrath
{"title":"Distortion-free sampling of ultrabroadband terahertz electric fields by interfacial spin accumulation","authors":"Alexander L. Chekhov,&nbsp;Yannic Behovits,&nbsp;Julius J. F. Heitz,&nbsp;Maria-Andromachi Syskaki,&nbsp;Samridh Jaiswal,&nbsp;Oliver Gueckstock,&nbsp;Bruno R. Serrano,&nbsp;Amon Ruge,&nbsp;Jana Kredl,&nbsp;Martin Wolf,&nbsp;Markus Münzenberg,&nbsp;Gerhard Jakob,&nbsp;Mathias Kläui,&nbsp;Tom S. Seifert,&nbsp;Tobias Kampfrath","doi":"10.1126/sciadv.adq7741","DOIUrl":"10.1126/sciadv.adq7741","url":null,"abstract":"<div >In spintronics, FM|HM stacks consisting of a ferromagnetic-metal (FM) and a heavy-metal (HM) layer are model systems for spin transport and spin-charge interconversion. To explore their potential as detectors for ultrabroadband terahertz electromagnetic pulses, we measure the transient optical birefringence the terahertz field induces. Notably, the signal component linear in the FM magnetization agrees excellently with the shape of the incident terahertz electric field at 1 to 13 terahertz and beyond. Analysis indicates that the birefringence arises from the terahertz-field–driven spin accumulation at the FM/HM interface through the spin Rashba-Edelstein effect (SREE). Because of spin-momentum locking, the SREE decays by electron momentum relaxation in &lt;10 femtoseconds, substantially faster than a spin-Hall-effect–induced bulk spin accumulation. Our experiment demonstrates straightforward spintronic sampling of intense ultrabroadband terahertz fields with flat amplitude and phase response. Furthermore, it provides temporal signatures of the SREE and can be viewed as a versatile implementation of interface-specific terahertz time-domain spectroscopy.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 12","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq7741","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143666306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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