Science Advances最新文献_第5页

Near-infrared spectroscopy–enabled electromechanical systems for fast mapping of biomechanics and subcutaneous diagnosis 用于快速绘制生物力学和皮下诊断图的近红外光谱机电系统

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-13 DOI: 10.1126/sciadv.adq9358

Yihang Wang, Josh Henderson, Priyash Hafiz, Pranav Turlapati, Daniel Ramsgard, Will Lipman, Yihan Liu, Lin Zhang, Zhibo Zhang, Brayden Davis, Ziheng Guo, Shuodao Wang, Lillian Seymour, Wanrong Xie, Wubin Bai

{"title":"Near-infrared spectroscopy–enabled electromechanical systems for fast mapping of biomechanics and subcutaneous diagnosis","authors":"Yihang Wang, Josh Henderson, Priyash Hafiz, Pranav Turlapati, Daniel Ramsgard, Will Lipman, Yihan Liu, Lin Zhang, Zhibo Zhang, Brayden Davis, Ziheng Guo, Shuodao Wang, Lillian Seymour, Wanrong Xie, Wubin Bai","doi":"10.1126/sciadv.adq9358","DOIUrl":"10.1126/sciadv.adq9358","url":null,"abstract":"<div >Fast and accurate assessment of skin mechanics holds great promise in diagnosing various epidermal diseases, yet substantial challenges remain in developing simple and wearable strategies for continuous monitoring. Here, we present a design concept, named active near-infrared spectroscopy patch (ANIRP) for continuously mapping skin mechanics. ANIRP addresses these challenges by integrating near-infrared (NIR) sensing with mechanical actuators, enabling rapid measurement (<1 s) of Young’s modulus, high spatial sensing density (~1 cm<sup>2</sup>), and high spatial sensitivity (<1 mm). Unlike conventional electromechanical sensors, NIR sensors precisely capture vibrational frequencies propagated from the actuators without needing ultraclose contact, enhancing wearing comfort. Demonstrated examples include ANIRPs for comprehensively moduli mapping of artificial tissues with varied mechanical properties emulating tumorous fibrosis. On-body validation of the ANIRP across skin locations confirms its practical utility for clinical monitoring of epidermal mechanics, promising considerable advancements in real-time, noninvasive skin diagnostics and continuous health monitoring.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq9358","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acoustofluidic tweezers via ring resonance 通过环形共振实现声流体镊子

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-13 DOI: 10.1126/sciadv.ads2654

Xianchen Xu, Ke Jin, Kaichun Yang, Ruoyu Zhong, Mingyuan Liu, Wesley Collyer, Shivam Jain, Ying Chen, Jianping Xia, Junfei Li, Shujie Yang, Earl H. Dowell, Tony Jun Huang

{"title":"Acoustofluidic tweezers via ring resonance","authors":"Xianchen Xu, Ke Jin, Kaichun Yang, Ruoyu Zhong, Mingyuan Liu, Wesley Collyer, Shivam Jain, Ying Chen, Jianping Xia, Junfei Li, Shujie Yang, Earl H. Dowell, Tony Jun Huang","doi":"10.1126/sciadv.ads2654","DOIUrl":"10.1126/sciadv.ads2654","url":null,"abstract":"<div >Ring resonator (RR) devices are closed-loop waveguides where waves circulate only at the resonant frequencies. They have been used in sensor technology and optical tweezers, but controlling micron-scale particles with optical RR tweezers is challenging due to insufficient force, short working distances, and photodamage. To overcome these obstacles, an acoustofluidic RR-based tweezing method is developed to manipulate micro-sized particles that can enhance particle trapping through the resonance interaction of acoustic waves with high <i>Q</i> factor (>3000), more than 20 times greater than traditional acoustic transducers. Particles can be precisely manipulated within the RR by adjusting the signal phase, with trapping amplified by enlarging the connected waveguide. Rapid particle mixing is achieved when particles are placed between the waveguide and RR. The signal path is strengthened by strategically positioning the RR in a two-dimensional plane. Acoustofluidic RR tweezers have immense potential for advancing applications in biosensing, mechanobiology, lab-on-a-chip, and cell-cell communication research.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.ads2654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Summer North Atlantic Oscillation, Arctic sea ice, and Arctic jet Rossby wave forcing 夏季北大西洋涛动、北极海冰和北极喷流罗斯比波强迫作用

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-13 DOI: 10.1126/sciadv.adk6693

Chris K. Folland, Tinghai Ou, Hans W. Linderholm, Adam A. Scaife, Jeff Knight, Deliang Chen

{"title":"The Summer North Atlantic Oscillation, Arctic sea ice, and Arctic jet Rossby wave forcing","authors":"Chris K. Folland, Tinghai Ou, Hans W. Linderholm, Adam A. Scaife, Jeff Knight, Deliang Chen","doi":"10.1126/sciadv.adk6693","DOIUrl":"10.1126/sciadv.adk6693","url":null,"abstract":"<div >We use Coupled Model Intercomparison Project Phase 6 (CMIP6) coupled and Atmospheric Model Intercomparison Project (AMIP) climate models, dynamical analyses, and observations to investigate interactions between summer Arctic sea ice concentration (SIC) variations and the Summer North Atlantic Oscillation (SNAO). Observations suggest that SIC-SNAO relationships mainly come from the East Siberian to Arctic Canada (ESAC) region where a weak atmospheric jet stream exists in summer. Twelve CMIP6 models with the most realistic atmospheric climatologies over the North Atlantic and Europe agree well with reanalyses on relationships between SIC and Northern Hemisphere atmospheric circulation. CMIP6 model data indicate that ESAC SIC influences the SNAO with a lead time of several weeks. However, AMIP simulations do not reproduce the observed atmospheric circulation when observed sea ice is prescribed. Rossby wave analyses do though support observed ESAC SIC influences on the SNAO. We conclude that ESAC Arctic SIC modestly influences the SNAO, and such investigations require the use of coupled models.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adk6693","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INF2 mutations cause kidney disease through a gain-of-function mechanism INF2 基因突变通过功能增益机制导致肾病

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-13 DOI: 10.1126/sciadv.adr1017

Balajikarthick Subramanian, Sarah Williams, Sophie Karp, Marie-Flore Hennino, Sonako Jacas, Miriam Lee, Cristian V. Riella, Seth L. Alper, Henry N. Higgs, Martin R. Pollak

{"title":"INF2 mutations cause kidney disease through a gain-of-function mechanism","authors":"Balajikarthick Subramanian, Sarah Williams, Sophie Karp, Marie-Flore Hennino, Sonako Jacas, Miriam Lee, Cristian V. Riella, Seth L. Alper, Henry N. Higgs, Martin R. Pollak","doi":"10.1126/sciadv.adr1017","DOIUrl":"10.1126/sciadv.adr1017","url":null,"abstract":"<div >Heterozygosity for inverted formin-2 (INF2) mutations causes focal segmental glomerulosclerosis (FSGS) with or without Charcot-Marie-Tooth disease. A key question is whether the disease is caused by gain-of-function effects on INF2 or loss of function (haploinsufficiency). Despite established roles in multiple cellular processes, neither INF2 knockout mice nor mice with a disease-associated point mutation display an evident kidney or neurologic phenotype. Here, we compared responses to puromycin aminonucleoside (PAN)–induced kidney injury between INF2 R218Q and INF2 knockout mice. R218Q INF2 mice are susceptible to glomerular disease, in contrast to INF2 knockout mice. Colocalization, coimmunoprecipitation analyses, and cellular actin measurements showed that INF2 R218Q confers a gain-of-function effect on the actin cytoskeleton. RNA expression analysis showed that adhesion and mitochondria-related pathways were enriched in the PAN-treated R218Q mice. Both podocytes from INF2 R218Q mice and human kidney organoids with an INF2 mutation (S186P) recapitulate adhesion and mitochondrial phenotypes. Thus, gain-of-function mechanisms drive INF2-related FSGS and explain this disease’s autosomal dominant inheritance.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adr1017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrically switchable chiral nonlinear optics in an achiral ferroelectric 2D van der Waals halide perovskite 非手性铁电二维范德华卤化物包晶中的电可切换手性非线性光学器件

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-13 DOI: 10.1126/sciadv.adq5521

Go Yumoto, Fuyuki Harata, Tomoya Nakamura, Atsushi Wakamiya, Yoshihiko Kanemitsu

{"title":"Electrically switchable chiral nonlinear optics in an achiral ferroelectric 2D van der Waals halide perovskite","authors":"Go Yumoto, Fuyuki Harata, Tomoya Nakamura, Atsushi Wakamiya, Yoshihiko Kanemitsu","doi":"10.1126/sciadv.adq5521","DOIUrl":"10.1126/sciadv.adq5521","url":null,"abstract":"<div >Two-dimensional (2D) van der Waals (vdW) semiconductors play a key role in developing nanoscale nonlinear optical devices. 2D Ruddlesden-Popper lead halide perovskites (RPPs) expand the potential of using 2D vdW semiconductors in nonlinear optical applications because they exhibit electrically switchable and chiral second-order optical nonlinearity originating from the emergence of ferroelectricity and chirality. However, electrically switchable chiral nonlinear optics has not yet been realized because of the difficulty in electrically manipulating chiral structures. Here, we demonstrate that chiral second-harmonic generation (SHG) can be electrically induced and switched in an achiral biaxial ferroelectric 2D RPP. We observe reversible and continuous electrical switching of SHG circular dichroism and large nonlinear chiroptical activity. Polarization-resolved SHG imaging reveals that electrical poling induces the ferroelectric multidomain structure arising from the biaxial nature of the material, and the planar chirality appears. Our findings show a simple electrical control of the nonlinear chiroptical responses and establish chiral nonlinear optics based on ferroelectric 2D RPPs.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq5521","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global expansion of wildland-urban interface intensifies human exposure to wildfire risk in the 21st century 21 世纪，全球野地-城市交接地带的扩张加剧了人类面临的野火风险。

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-08 DOI: 10.1126/sciadv.ado9587

Yongxuan Guo, Jianghao Wang, Yong Ge, Chenghu Zhou

{"title":"Global expansion of wildland-urban interface intensifies human exposure to wildfire risk in the 21st century","authors":"Yongxuan Guo, Jianghao Wang, Yong Ge, Chenghu Zhou","doi":"10.1126/sciadv.ado9587","DOIUrl":"10.1126/sciadv.ado9587","url":null,"abstract":"<div >Rapidly increasing human-nature interactions exacerbate the risk of exposure to wildfires for human society. The wildland-urban interface (WUI) represents the nexus of human-nature interactions, where the risk of exposure to natural hazards such as wildfire is most pronounced. However, quantifying long-term global WUI change and the corresponding driving factors at fine resolution remain challenging. Here, we mapped and analyzed the global WUI at 30-meter resolution in 2000, 2010, and 2020. Our analysis revealed that the global WUI expanded by 35.6% since 2000, reaching 1.93 million square kilometer in 2020. Notably, 85% of this growth occurred between 2010 and 2020. The increase in WUI was primarily driven by the unprecedented expansion of global urbanization, contributing an additional 589,914 square kilometer of WUI. In addition, the number of small fires occurring in WUI areas has increased substantially since 2010. These findings underscore the rising wildfire risk to human society and highlight the urgency of implementing tailored fire management strategies in WUI areas.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contemporary small-scale subsistence populations offer unique insights into human musculoskeletal health and aging 当代自给自足的小规模人群为了解人类肌肉骨骼健康和衰老提供了独特的视角。

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-08 DOI: 10.1126/sciadv.adq1039

Jonathan Stieglitz

{"title":"Contemporary small-scale subsistence populations offer unique insights into human musculoskeletal health and aging","authors":"Jonathan Stieglitz","doi":"10.1126/sciadv.adq1039","DOIUrl":"10.1126/sciadv.adq1039","url":null,"abstract":"<div >Human foragers avoid noncommunicable diseases that are leading causes of mortality, partly because physically active lifestyles promote healthy aging. High activity levels also promote tissue damage accumulation from wear-and-tear, increase risk of injury and disability which compromise productivity, and reduce energetic investments in somatic maintenance given constrained energy expenditure. Constraints intensify when nutrient supply is limited and surplus energy is directed toward pathogen defense and reproduction, as occurred throughout hominin evolution. This paper reviews evidence linking exposomes to musculoskeletal health in subsistence populations, focusing on effects of physical activity, pathogens, diet, and reproduction. Chronic musculoskeletal conditions are common for humans and possibly prehistoric hominins but rarer in quadrupedal apes. We propose that transition to bipedalism ~6 to 8 million years ago constituted an early “mismatch scenario,\" increasing hominin susceptibility to musculoskeletal conditions vis-à-vis quadrupedal apes due to changes in mechanical loading environments. Mismatched musculoskeletal traits were not targets of selection because of trade-offs favoring bipedal extractive foraging and higher fertility.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adq1039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual function of overexpressing plasma membrane H+-ATPase in balancing carbon-water use 过表达质膜 H+-ATP 酶在平衡碳水利用中的双重功能

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-08 DOI: 10.1126/sciadv.adp8017

Hangjin Jiang, Jinghan Su, Zirong Ren, Dexian Wang, Adrian Hills, Toshinori Kinoshita, Michael R. Blatt, Yin Wang, Yizhou Wang

{"title":"Dual function of overexpressing plasma membrane H+-ATPase in balancing carbon-water use","authors":"Hangjin Jiang, Jinghan Su, Zirong Ren, Dexian Wang, Adrian Hills, Toshinori Kinoshita, Michael R. Blatt, Yin Wang, Yizhou Wang","doi":"10.1126/sciadv.adp8017","DOIUrl":"10.1126/sciadv.adp8017","url":null,"abstract":"<div >Stomata respond slowly to changes in light when compared with photosynthesis, undermining plant water-use efficiency (WUE). We know much about stomatal mechanics, yet efforts to accelerate stomatal responsiveness have been limited despite the breadth of potential targets for manipulation. Here, we use mechanistic modeling to establish a hierarchy of putative targets affecting stomatal kinetics. Counterintuitively, modeling predicted that overexpressing plasma membrane H<sup>+</sup>-ATPases could speed stomata and enhance WUE under fluctuating light, even though overexpressed H<sup>+</sup>-ATPases is known to promote stomatal opening and reduce WUE in the steady state. Experiments validated the prediction, implicating an unexpected role of the H<sup>+</sup>-ATPases in improving WUE under fluctuating light. It suggests that H<sup>+</sup>-ATPases have a dual function, acting as a facilitator of carbon assimilation and water use, depending on the light conditions. These findings highlight the importance of integrating in silico modeling with experiments in future efforts toward enhancing stomatal function.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic overrepresentation of accumbal cues in food- and opioid-seeking rats after prenatal THC exposure 产前暴露于四氢大麻酚后，食物和阿片类药物觅食大鼠的累积性线索动态过度呈现。

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-08 DOI: 10.1126/sciadv.adq5652

Miguel Á. Luján, Reana Young-Morrison, Sonia Aroni, István Katona, Miriam Melis, Joseph F. Cheer

{"title":"Dynamic overrepresentation of accumbal cues in food- and opioid-seeking rats after prenatal THC exposure","authors":"Miguel Á. Luján, Reana Young-Morrison, Sonia Aroni, István Katona, Miriam Melis, Joseph F. Cheer","doi":"10.1126/sciadv.adq5652","DOIUrl":"10.1126/sciadv.adq5652","url":null,"abstract":"<div >The increasing prevalence of cannabis use during pregnancy has raised medical concerns, primarily related to Δ9-tetrahydrocannabinol (THC), which readily crosses the placenta and affects fetal brain development. Previous research has identified dopaminergic alterations related to maternal THC consumption. However, the consequences that prenatal cannabis exposure (PCE) has on striatum-based processing during reward pursuit have not been determined. Here, we characterize PCE rats during food or opioid-maintained reward seeking. We find that the supramotivational phenotype of PCE rats is independent of value-based processing and is instead related to augmented reinforcing efficiency of opioid rewards. Our findings reveal that prenatal THC exposure leads to increased cue-evoked dopamine responses and an overrepresentation of effort-driven striatal encoding patterns. Recapitulating clinical findings, drug-related PCE adaptations were more pronounced in males, who showed increased vulnerability for relapse. Collectively, these findings indicate that prenatal THC exposure in male rats engenders a pronounced neurodevelopmental susceptibility to addiction-like disorders.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leaftronics: Natural lignocellulose scaffolds for sustainable electronics 叶电子学：用于可持续电子产品的天然木质纤维素支架。

IF 11.7 1区综合性期刊

Science Advances Pub Date : 2024-11-08 DOI: 10.1126/sciadv.adq3276

Rakesh R. Nair, Jakob Wolansky, Kai Uhlig, Ali Solgi, Laura Teuerle, Tianyi Zhang, Jonas Schröder, Tobias Antrack, Johannes Benduhn, Hans Kleemann, Karl Leo

{"title":"Leaftronics: Natural lignocellulose scaffolds for sustainable electronics","authors":"Rakesh R. Nair, Jakob Wolansky, Kai Uhlig, Ali Solgi, Laura Teuerle, Tianyi Zhang, Jonas Schröder, Tobias Antrack, Johannes Benduhn, Hans Kleemann, Karl Leo","doi":"10.1126/sciadv.adq3276","DOIUrl":"10.1126/sciadv.adq3276","url":null,"abstract":"<div >The global rise in electronic waste is alarming, driven by the persistent use of glass, epoxy, and plastic substrates owing to their cost, stability, flexibility, and transparency. This underscores the need for biodegradable alternatives with similar properties. This study shows that leaf-derived lignocellulose scaffolds can stabilize bio-sourced, solution-processed polymers by acting as natural sequestering media. Such reinforced films, even when based on gelatin (<i>T</i><sub>g</sub> ~ 60°C), can endure processes over 200°C. We demonstrate dip-coated ethyl cellulose films for commercially viable reflow soldered circuitry. The films offer high flexibility, more than 80% transparency, and surface roughness below 5.5 nm. Advanced OPDs and OECTs fabricated on these films perform comparably to those on glass and the low material cost and simple fabrication process yields a minimal carbon footprint of 1.6 kgCO<sub>2</sub>/m<sup>2</sup>. This work thus opens a vista of possibilities for biodegradable polymers heretofore considered unsuitable for making temperature-stable substrates for state-of-the-art electronics applications.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":null,"pages":null},"PeriodicalIF":11.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0