Recent patents on biotechnology最新文献

{"title":"Curcumin-assisted Preparation of α-Fe₂O₃@TiO₂ Nanocomposites for Antibacterial and Photocatalytic Activity.","authors":"Anuskha Kala, Krati Saini, Sanjeev Kimothi, Rashmi Verma, Kamal K Kar, Pankaj Chamoli","doi":"10.2174/0118722083332040241011050802","DOIUrl":"10.2174/0118722083332040241011050802","url":null,"abstract":"<p><strong>Background: </strong>Harmful microorganisms like pathogens significantly impact human health. Meanwhile, industrial growth causes pollution and water contamination by releasing untreated hazardous waste. Effective treatment of these microorganisms and contaminants is essential, and nanocomposites may be a promising solution. The present attempt demonstrates the green synthesis of α-Fe<sub>2</sub>O<sub>3</sub>@TiO<sub>2</sub> nanocomposites (FTNCs) for the effective treatment of pathogens and organic contaminants.</p><p><strong>Methods: </strong>The FTNCs have been synthesized through a green approach utilizing curcumin extract. Curcumin (Turmeric) extract (TEx) was prepared by washing, drying, and crushing 5 g of turmeric, then boiling it in 100 mL distilled water at 70°C for 1 hour. Metal salts (Fe<sup>3</sup>+/Ti<sup>4+</sup>, 2:1) were added to 100 mL of TEx under continuous stirring at 70°C for 24 h. The solution was rinsed and dried at 80°C overnight and heated at 300°C for 3 h to remove impurities.</p><p><strong>Results: </strong>Synthesized FTNCs have been tested for the potent antibacterial activity against both Gram-positive (<i>Staphylococcus aureus, Bacillus subtilis, Enterococcus faecalis)</i> and Gram-negative bacteria (<i>Escherichia coli, Salmonella Abony, Pseudomonas sp.</i>). Observations discovered noteworthy inhibition of both Gram-positive and Gramnegative bacteria by FTNCs. Furthermore, the FTNCs system shows the energy band gap of ~2.6 eV which may suppress electron recombination, thereby enhancing photocatalysis. The photo-degradation is examined against Evans blue (EB) and Congo red (CR) dyes under UV and visible light (125 W) irradiation. The remarkable photocatalytic degradation efficiency (DE) for CR reached ~67.4% in 60 min.</p><p><strong>Conclusion: </strong>A simple green approach has been demonstrated for the synthesis of the FTNCs using curcumin-mediated reduction. As prepared FTNCs have been evaluated for potent antibacterial activity against both Gram-positive (<i>Staphylococcus aureus, Bacillus subtilis, Enterococcus faecalis</i>) and Gram-negative bacteria (<i>Escherichia coli, Salmonella Abony, Pseudomonas sp.</i>). The results show that the highest zone of inhibition diameter values have been obtained for 5 mg/mL concertation of FTNCs of ~14, 22, 18, 21, and 20 and 29 mm for <i>E. coli, S. abony, S. aureus, B. subtilis, E. faecalis</i>, and <i>Pseudomonas sp.,</i> respectively. Additionally, FTNCs demonstrate remarkable photocatalytic degradation efficiency against EB and CR dyes under UV (125 W) irradiation, achieving 56, 67% degradation within 60 min, respectively. The findings indicate that FTNCs show long-term antimicrobial effectiveness and potential for water treatment through photocatalysis. This examination highlights recent advancements in intellectual property rights (IPR) and patent strategies, shedding light on how patents influence eco-friendly synthesis and the development of multifun","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":"331-345"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Edible Vaccines: A Patent-Driven Exploration of Immunization Technologies.","authors":"Sahil Kashyap, Rohit Kamboj, Shikha Kamboj, Kumar Guarve, Sweta Kamboj","doi":"10.2174/0118722083275041231219060829","DOIUrl":"10.2174/0118722083275041231219060829","url":null,"abstract":"<p><p>Vaccines are biological preparations that improve immunity to particular diseases. Particularly for poor developing nations, edible vaccines show significant potential as a financially advantageous, simple to administer, straightforward to store, fail-safe, and socially and culturally acceptable vaccine delivery system. A vaccine incorporates the gene-encoding bacterial or viral disease-causing agent in plants without losing its immunogenic property. Potatoes, tomatoes, rice, soybeans, and bananas are the primary plants for edible vaccines. It activates the systemic and mucosal immunity responses against a foreign disease-causing organism. It offers exciting possibilities to reduce diseases like hepatitis B, rabies, HIV/AIDS (human immunodeficiency virus infection and acquired immune deficiency syndrome), etc. These vaccines provide many benefits, like being convenient to administer, efficiently storing, and readily acceptable drug delivery systems for patients of different age groups. So, an edible vaccine may be the most convenient vaccine to improve immunity. However, there are a lot of technical and regulatory challenges to overcome in the way of edible vaccine technology. Though all seem surmountable, various technical obstacles and regulatory and non-scientific challenges need to be overcome. Moreover, edible vaccine patents represent a cutting-edge area of biotechnology, where the integration of genetic material into edible substances holds great promise for revolutionizing vaccination methods. These patents aim to harness the potential of plants and other edibles to stimulate immune responses, offering a potential alternative to traditional injectable vaccines. This review states the technologies, host plants, current status, recent patents, the future of this new preventive modality, and different regulatory issues concerning edible vaccines.</p>","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":"99-112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139567388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of Polyhydroxybutyrate (PHB) Production Potential of Photosynthetic Microbes: A Sustainable Source of Bioplastic.","authors":"Saima Shahzad Mirza, Kanza Yaseen, Sumaira Aslam, Ammara Fatima, Mohammad Hossein Morowvat, Ayesha Ishaque, Kalsoom Fatima","doi":"10.2174/0118722083295143241220054012","DOIUrl":"https://doi.org/10.2174/0118722083295143241220054012","url":null,"abstract":"<p><strong>Introduction: </strong>The present study examined Polyhydroxy butyrate production (PHB) potential of different photosynthetic microbes such as Chlorella vulgaris, Scenedesmus obliquus and Rhodobacter capsulatus-PK under different nutrient conditions. Biodegradable bioplastics, such as Poly-β-hydroxybutyrates (PHB), derived from these microbes provide a sustainable alternative to conventional petroleum-based nondegradable plastics.</p><p><strong>Background: </strong>As the demand for clean and sustainable alternatives rises, bio-plastic is gaining attention as a viable substitute to conventional plastics. However, conventional sources of bio-plastic production have inherent limitations, which can be effectively addressed through the utilization of photosynthetic microbes e.g. microalgae, purple non sulphur bacteria.</p><p><strong>Methodology: </strong>The production of bioplastic was evaluated by cultivating the microalgae in BG-11, BBM and PNSB in synthetic growth media (MI, MII) with different nitrogen concentrations of 0%, 50% and 100%. The biopolymer (PHB) was obtained from all experiments in a wide range of concentration (7-42.8%) of dry cell weight (DCW).</p><p><strong>Results: </strong>In this study, algal isolate SK1 demonstrated the highest PHB content (42.8%) in BBM under 100% nitrogen starvations rendering the bioplastic exceptionally compatible and suitable for eco-friendly applications. Additionally, various patents cited by different authors on different aspects of microbial bioplastic production.</p><p><strong>Conclusion: </strong>Nutrition depletion such as nitrogen scarcity induced stressful growth conditions that resulted in highest accumulation of the biopolymer PHB. Optimizing nitrogen availability is key to maximizing PHB production, making it a viable sustainable alternative to conventional plastics.</p>","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Green-Synthesized Nanoparticles on Dental Caries-Causing Bacteria: A Systematic Review.","authors":"Asma Sepahdar, Behnoush Selahbarzin, Atoosa Vaez Naini, Samira Jafari, Mehrnaz Moradi, Pegah Shakib","doi":"10.2174/0118722083343723241204053839","DOIUrl":"https://doi.org/10.2174/0118722083343723241204053839","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;In this study, a comprehensive search was conducted across multiple databases, including PubMed, Google Scholar, SID, Scopus, Medline, and Web of Science, as well as selected herbal medicine journals. The inclusion of herbal medicine journals was justified by the growing interest in green-synthesized nanoparticles derived from plant extracts, which are relevant to the focus of this review. Articles published between 2015 and 2023 were evaluated. To ensure a robust selection process, studies were assessed for quality using specific criteria beyond the AXIS checklist, including study design, sample size, and methodological rigor. Any discrepancies between reviewers were resolved through discussion or consultation with a third reviewer. This approach aimed to minimize bias and ensure the inclusion of high-quality studies that contribute meaningfully to the review's objectives.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The primary objective of this review was to investigate the therapeutic implications of green-synthesized metallic nanoparticles, such as silver and zinc nanoparticles, in addressing dental caries, with a focus on their antibacterial properties and potential to improve current treatment modalities.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;In this study, PubMed, Google Scholar, SID, Scopus, Medline, Web of Science, and herbal medicine journals were searched, and articles from 2015 to 2023 were evaluated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In this study, 22 clinical trials were reviewed, and the effectiveness of synthesized nanoparticles was demonstrated in nearly all of them. The nanoparticles found to be most effective against tooth decay-causing bacteria include silver, zinc, selenium, nickel, and copper nanoparticles. To provide greater clarity, key findings, such as nanoparticle size, minimum inhibitory concentration (MIC) values, and specific antibacterial effects, are presented in a table. Additionally, a more in-depth comparison was made between these nanoparticles, focusing on their relative effectiveness under different conditions. For example, silver nanoparticles were consistently effective across various trials due to their strong antimicrobial properties, while zinc and copper nanoparticles showed efficacy in specific concentrations and against particular bacterial strains. Furthermore, green-synthesized nanoparticles were compared with those produced using traditional methods, evaluating factors, such as effectiveness, scalability, and safety, to provide a comprehensive understanding of their potential in dental caries treatment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;According to the literature review, nanoparticles with antibacterial properties have the potential to serve as an alternative or complement to conventional chemical treatments for combating tooth decay. Future research should focus on exploring specific types of nanoparticles, such as green-synthesized metallic nanoparticles (e.g., sil","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biosurfactants Used in the Bioremediation of Soils Contaminated With Hydrocarbons - Overview of the State of the Art and Future Perspectives.","authors":"Maria Auxiliadora de Oliveira, Vinícius Souza Tarabal, Felipe Ferreira Silva, Diego Fernandes Livio, Daniela Regiane da Silva, Adriano Guimarães Parreira, Daniel Bonoto Gonçalves, José Antônio da Silva, Pedro Pires Goulart Guimarães, Paulo Afonso Granjeiro","doi":"10.2174/0118722083343490241130163344","DOIUrl":"https://doi.org/10.2174/0118722083343490241130163344","url":null,"abstract":"<p><strong>Background: </strong>The increasing industrialization and hydrocarbon use have led to concerning soil contamination. Oil spills and improper disposal of oily waste pose threats to ecosystems and human health. The recovery of these environments is essential, but separating oily components from soil remains challenging. Current bioremediation strategies using synthetic surfactants can cause secondary contamination. Microbial biosurfactants, which are biodegradable and low in toxicity, emerge as promising solutions, and this study reviews methods for utilizing these biosurfactants in the environmental bioremediation of hydrocarbons.</p><p><strong>Objective: </strong>This study explores the efficient and eco-friendly use of biosurfactants for hydrocarbon- contaminated soil management, providing a market-oriented analysis of recent patents and trends, and highlighting the transition from academic research to industrial applications.</p><p><strong>Method: </strong>The methodology involves an extensive literature review, careful selection of recent studies and patents on biosurfactants in hydrocarbon bioremediation, critical analysis of in-situ and ex-situ application methods, assessment of commercial viability, and synthesis of findings to contribute to sustainable solutions in contaminated environments.</p><p><strong>Conclusion: </strong>The present study demonstrates the extensive applicability of biosurfactants across various industrial sectors. The increasing interest in incorporating biosurfactants into industrial processes is driven by the pressing need for sustainable solutions to address tangible market challenges. Notably, the cosmetics industry exhibited the highest number of patents related to the use of biosurfactants, underscoring its significant role in advancing the adoption of these environmentally friendly agents. This trend highlights the critical demand for sustainable alternatives in product formulations and underscores the pivotal role of biosurfactants in fostering eco-innovation within the industry.</p>","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifungal Activity of Alcoholic Extract of Allium Jesdianum on Fungi-Contaminated Dairy Products.","authors":"Fatemeh Fallahi, Shirin Naghdifar, Zahra Sadri Irani, Seyed Mohammad Mahdi Kazemi, Pegah Shakib, Mahboobeh Madani","doi":"10.2174/0118722083332626241129061731","DOIUrl":"https://doi.org/10.2174/0118722083332626241129061731","url":null,"abstract":"<p><strong>Background: </strong>One of the main sources of contaminated dairy products is moldy fungi, specifically species of Aspergillus and Penicillium. This study aimed to evaluate the effect of the alcoholic extract of Allium jesdianum plant on the growth of molds contaminating dairy products in Isfahan.</p><p><strong>Materials and methods: </strong>In this research, 200 samples of dairy products were gathered from different areas of Isfahan city, including 70 samples of cheese, 60 samples of buttermilk, 40 samples of yogurt, 20 samples of curd, and 10 samples of cream. The antifungal activity of Allium jesdianum plant was investigated by the diffusion method in disc, well, and agar dilution in various concentrations. Minimum inhibitory concentration (MIC) and minimum fatal concentration (MFC) were also determined. Aspergillus, Penicillium, Cladosporium, and Acremonium fungi were the most commonly found fungal contaminants of this investigation. Antifungal activity was not observed by disc diffusion and well diffusion methods.</p><p><strong>Results: </strong>In the agar dilution method, ethanolic and methanolic extracts of stem and leaves in concentrations of 80, 60, 40, and 30 mg/ml, and ethanolic and methanolic extracts of plant bulbs in concentrations of 60 and 30 mg/ml revealed antifungal activity against Aspergillus niger, Penicillium notatum, and Penicillium chrysogenum. The MIC of stem and leaf ethanol extracts and onion ethanol for Aspergillus niger was 18.7, and for Penicillium notatum and Penicillium chrysogenum, it was 37.5, 37.5, 37.5, and 37.5 mg/ml. Fungal contamination of dairy products is a serious threat to the public health of society. Therefore, identifying medicinal plants with antifungal activity can be an effective step in preventing fungal contamination and increasing the shelf life of these products.</p><p><strong>Conclusion: </strong>The results of this research have shown that the Allium jesdianum plant can inhibit the growth of Aspergillus niger, Penicillium notatum, and Penicillium chrysogenum.</p>","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Effect of Formononetin Against the Periodental Pathogens Enterococcus faecalis and Candida albicans.","authors":"Negar Delfan, Maryam Dalaei Moghadam, Pegah Shakib, Asma Sepahdar, Zahra Naghibeiranvand","doi":"10.2174/0118722083342082241129060918","DOIUrl":"https://doi.org/10.2174/0118722083342082241129060918","url":null,"abstract":"<p><strong>Background: </strong>Among the bioactive isoflavones identified from different plants is formononetin. Formononetin's antioxidant, anti-inflammatory, and anti-cancer qualities have all received a lot of attention lately. The goal of the current investigation was to examine formononetin's antifungal and antibacterial activity against Candida albicans and Enterococcus faecalis in vitro, respectively.</p><p><strong>Methods: </strong>The present study determined the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and Minimum Fungicidal Concentration (MFC) of formononetin, chlorhexidine, formononetin + chlorhexidine, Formononetin+ nystatin, and nystatin against E. faecalis and C. albicans isolates. Next, SPSS version 25 was used to analyze the data. A significance cutoff of P<0.05 was taken into account.</p><p><strong>Results: </strong>Chlorhexidine + formononetin and formononetin alone had the greatest and lowest minimum inhibitory concentrations (MIC) against E. faecalis, at 6.6 and 18.3 μg/ml, respectively. With MIC values of 0.66 and 8.3 μg/ml against a C. albicans isolate sensitive to nystatin, the combination of formononetin + nystatin and formononetin alone was shown to have the greatest and lowest anti-candida effects.</p><p><strong>Conclusion: </strong>The findings demonstrated a considerably greater antibacterial effect (P<0.05) for the combinations of formononetin + nystatin and chlorhexidine as compared to nystatin and chlorhexidine alone.</p>","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospects of Plant Derived Bioactive Compounds as Nanoparticles for Biotechnological Applications.","authors":"N. Bano, Syed Khalida Izhar, Anamika Gupta, M. Zaheer, Roohi","doi":"10.2174/0118722083301253240417114400","DOIUrl":"https://doi.org/10.2174/0118722083301253240417114400","url":null,"abstract":"Nanoparticles bestow beneficial impacts on plants, specifically in increasing photosynthetic capacity and germination rate, pesticide delivery, managing pathogenicity and enhancing nutrient supply. The nanoparticles produced from the medicinal plant extracts are identified as an exceptional applicant in nanomedicine, cosmetics, and agriculture for the treatment of diseases as antimicrobial, antioxidant and anticancer agents, etc. Plant extracts actually have bioactive metabolites that provide therapeutic potential against a variety of diseases. Herein, we review the production of bioactive compounds from leaves, roots, seeds, flowers and stems. We further summarize the different methods for obtaining plant extracts and the green technologies for the synthesis of nanoparticles of plant derived bioactive compounds. Biotechnological aspects of these synthesized nanoparticles are also added here as highlights of this review. Overall, plant derived nanoparticles provide an alternative to conventional approaches for drug delivery as well and present exciting opportunities for future research on novel areas.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":" 576","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140682560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decarbonizing the Transport of Microalgae-based Products - The Role of E-mobility.","authors":"R. R. Dias, Mariany C. Deprá, Victor Cesar Rodrigues Carvalho, Cristiano Ragagnin de Menezes, L. Q. Zepka, E. Jacob‐Lopes","doi":"10.2174/0118722083305025240409071630","DOIUrl":"https://doi.org/10.2174/0118722083305025240409071630","url":null,"abstract":"BACKGROUND\u0000The decarbonization of road transport is a precondition for achieving carbon neutrality. Battery-electric vehicle technology can make this a reality. In this bias, the objective of the article is to shed light on the ongoing debate about the potentially important role of the adoption of electric vehicles in the transport of microalgae- based products to help them advance to a cleaner life cycle.\u0000\u0000\u0000METHODS\u0000Five routes, including unimodal and multimodal conditions, were defined to assess the carbon emissions of the transport system and, more specifically, of road transport. The headquarters of market-leading microalgae manufacturers were selected as the origin of the routes and, as the destination, regions that sustain them.\u0000\u0000\u0000RESULTS\u0000The results reveal the supremacy of road transport of microalgae-based products using electric vehicles powered by nuclear, hydroelectric, and wind, followed by biomass and photovoltaic energy. They also show that the positive impact of wind, water, and photovoltaic energy on the climate, added to the lower battery charging costs and the greater opportunity to generate revenue from the sale of carbon credits, make their tradeoffs.\u0000\u0000\u0000CONCLUSION\u0000The exquisite results of this study convey key messages to decision-makers and stakeholders about the role of electromobility in building a zero-carbon delivery route.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":"20 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140700922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional Health Connection of Algae and its Pharmaceutical Value as Anticancer and Antioxidant Constituents of Drugs","authors":"S. Mirza, Sidra Akbar, Muhammad Umer Ijaz, Mohammad Hossein Morowvat, Ayesha Ishaque, Kalsoom Fatima","doi":"10.2174/0118722083287672240321081428","DOIUrl":"https://doi.org/10.2174/0118722083287672240321081428","url":null,"abstract":"\u0000\u0000The marine environment is one of the major biomass producers of algae and\u0000seaweed; it is rich in functional ingredients or active metabolites with valuable nutritional\u0000health effects. Algal Metabolites derived from the cultivation of both microalgae and\u0000macroalgae may positively impact human health, offering physiological, pharmaceutical\u0000and nutritional benefits. Microalgae have been widely used as novel sources of bioactive\u0000substances. Bioactive polymers extracted from algae, such as algal fucans, Galatians, alginates\u0000phenolics, carotenoids, vitamin B12, and peptides possess antioxidant, anticoagulant,\u0000antimicrobial, antiviral, anti-inflammatory, anti-allergy, anticancer, and hypocholesterolemic\u0000properties. It emphasizes that using marine-derived compounds with bioactive\u0000properties as functional food ingredients may help promote human health and prevent\u0000chronic diseases. Utilizing bioactive compounds has demonstrated notable advantages in\u0000terms of effectiveness more than conventional treatments and therapies currently in use.\u0000Despite the availability of numerous microalgae-derived products catering to human\u0000health and nutrition in the market, there remains a lack of social acceptance and awareness\u0000regarding the health benefits of microalgae. Hence, this review aims to offer a comprehensive\u0000account of the current knowledge on anticancers, antioxidants, commercially\u0000available edible algal products and therapeutics isolated from algae.\u0000","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":"24 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}