揭开蒽醌的神秘面纱:重要次级代谢物的多种健康益处。

Q3 Biochemistry, Genetics and Molecular Biology
Mushfa Khatoon, Amita Dubey, Janhvi Km Verma
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引用次数: 0

摘要

自古以来,植物就被用来治疗多种疾病。植物的药理特性得益于萜类、黄酮类、生物碱等次生代谢物的存在。蒽醌是一组天然存在的醌类化合物,广泛存在于各种植物物种中。据报道,蒽醌类化合物具有治疗多种疾病的功效,因此备受关注。蒽醌类化合物的化学结构复杂,加上其固有的药用特性,凸显了它们作为治疗药物的潜力。它们具有多种治疗特性,如润肠通便、抗肿瘤、抗疟、抗菌、抗真菌、抗氧化等。蒽醌类化合物以不同的形式(衍生物)存在于植物中,由于其结构和化学性质,它们具有多种药用特性。在高等植物中,蒽醌类化合物的生物合成前体由不同途径提供,如质体半萜 2-C-甲基-D-赤藓醇-4-磷酸酯(MEP)、甲羟戊酸(MVA)、异橙皮苷酸合成酶和多酮类化合物。通过对科学文献进行深入分析,本综述深入探讨了蒽醌生物合成之间错综复杂的相互作用及其对人类健康的广泛贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unveiling Anthraquinones: Diverse Health Benefits of an Essential Secondary Metabolite.

Since ancient times, plants have been used as a remedy for numerous diseases. The pharmacological properties of plants are due to the presence of secondary metabolites like terpenoids, flavonoids, alkaloids, etc. Anthraquinones represent a group of naturally occurring quinones found generously across various plant species. Anthraquinones attract a significant amount of attention due to their reported efficacy in treating a wide range of diseases. Their complex chemical structures, combined with inherent medicinal properties, underscore their potential as agents for therapy. They demonstrate several therapeutic properties such as laxative, antitumor, antimalarial, antibacterial, antifungal, antioxidant, etc. Anthraquinones are found in different forms (derivatives) in plants, and they exhibit various medicinal properties due to their structure and chemical nature. The precursors for the biosynthesis of anthraquinones in higher plants are provided by different pathways such as plastidic hemiterpenoid 2-C-methyl-D-erthriol4-phosphate (MEP), mevalonate (MVA), isochorismate synthase and polyketide. By conducting a thorough analysis of scientific literature, this review provides insights into the intricate interplay between anthraquinone biosynthesis and its broad-ranging contributions to human health.

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来源期刊
Recent patents on biotechnology
Recent patents on biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
2.90
自引率
0.00%
发文量
51
期刊介绍: Recent Patents on Biotechnology publishes review articles by experts on recent patents on biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.
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