The Landscape of Products for Diabetic Peripheral Neuropathy: A Scientific and Patent Systematic Review.

Q3 Biochemistry, Genetics and Molecular Biology

Recent patents on biotechnology Pub Date : 2024-08-27 DOI:10.2174/0118722083314714240820115610

Giselda Dos Santos Barros, Paula Dos Passos Menezes, Simone de Cássia Silva, Gabriel Francisco da Silva

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引用次数: 0

Abstract

Background: Diabetic peripheral neuropathy (DPN) is a complication of diabetes that occurs in 40 - 60 million individuals worldwide and is associated with other chronic diseases. However, there are no review studies that present the state-of- the- art and technologies developed to circumvent this important health problem.

Material and methods: This review was conducted based on scientific papers and patents. The papers were retrieved from Lilacs, PubMed, and Web of Science databases, and the patents from INPI, ESPACENET, WIPO, and GOOGLE PATENTS. Thus, a sample consisting of 14 scientific articles and 667 patents was analyzed.

Results: From the analysis of the data, we drew an overview of the development of biomedical technologies for DPN and detected the pioneering spirit of China, the USA, and Japan in the area, with a focus on the treatment of DPN. Based on this, we carried out a SWOT analysis to help direct future efforts in the area, which should focus primarily on developing technologies for prevention, early diagnosis, and, above all, cure of the disease to reduce the important impact of this disease in various sectors of society.

Conclusion: This study finds a concentration of diabetic peripheral neuropathy products, especially therapeutic drugs, in high-income countries. It highlights the need for global collaboration and strategic focus on therapeutic adherence and preventive strategies to effectively manage DPN.

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糖尿病周围神经病变产品的现状：科学与专利系统回顾

背景：糖尿病周围神经病变（DPN）是糖尿病的一种并发症，全世界有 4,000-6,000 万糖尿病患者，并与其他慢性疾病相关。然而，目前还没有综述性研究介绍最新技术和为解决这一重要健康问题而开发的技术：本综述以科学论文和专利为基础。论文来自 Lilacs、PubMed 和 Web of Science 数据库，专利来自 INPI、ESPACENET、WIPO 和 GOOGLE PATENTS。因此，我们分析了由 14 篇科学论文和 667 项专利组成的样本：结果：通过对数据的分析，我们得出了针对 DPN 的生物医学技术的发展概况，并发现了中国、美国和日本在该领域的开拓精神，重点是 DPN 的治疗。在此基础上，我们进行了 SWOT 分析，以帮助指导该领域未来的工作，其主要重点应放在开发预防、早期诊断，尤其是治愈该疾病的技术上，以减少该疾病对社会各部门的重要影响：本研究发现，糖尿病周围神经病变产品，尤其是治疗药物，主要集中在高收入国家。它强调了全球合作的必要性，以及将战略重点放在坚持治疗和预防策略上以有效控制糖尿病周围神经病变的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Recent patents on biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

2.90

自引率

0.00%

发文量

期刊介绍： Recent Patents on Biotechnology publishes review articles by experts on recent patents on biotechnology. A selection of important and recent patents on biotechnology is also included in the journal. The journal is essential reading for all researchers involved in all fields of biotechnology.