Quintessence international最新文献

{"title":"Association between migration history and oral health: results of the 6th German Oral Health Study (DMS • 6).","authors":"Berit Lieske, Liane Schenk, Kathrin Kuhr, Vinay Pitchika, Katrin Borof, A Rainer Jordan, Ghazal Aarabi","doi":"10.3290/j.qi.b5982024","DOIUrl":"https://doi.org/10.3290/j.qi.b5982024","url":null,"abstract":"<p><strong>Objectives: </strong>Studies have demonstrated a significant association between migration history and oral health. Even after adjusting for confounders, migration history remains an independent risk factor for poorer oral health. As part of the 6th German Oral Health Study (DMS • 6), disease and care prevalence among individuals with migration history was surveyed at the population level. This article aims to assess the relationship between migration history, education status, and oral health.</p><p><strong>Method and materials: </strong>The analyses of the relationship between migration history and various oral health outcomes were conducted separately for younger adolescents (12-year-olds), adults (20-year-olds, 35- to 44-year-olds, 43- to 52-year-olds), and seniors (65- to 74-year-olds, 73- to 82-year-olds).</p><p><strong>Results: </strong>A significant association between migration history and poorer oral health outcomes, as well as less favorable oral health behaviors, was observed across all age groups. After adjusting for age, gender, and education, individuals with migration history exhibited higher levels of plaque, more bleeding sites, a higher prevalence of decayed teeth, insufficient tooth brushing frequency, and complaint-oriented dental service utilization.</p><p><strong>Conclusion: </strong>Previous studies have consistently identified education as a risk factor for poorer oral health. In the present study, even after adjusting for education status in multivariate models, the association between migration history and oral health outcomes remained significant. This finding underscores migration history as an independent risk factor for poorer oral health outcomes. This is the first large-scale cohort study in Germany to analyze the relationship between migration history and multiple oral health outcomes across different age groups. Future research should focus on uncovering migration-related factors, health literacy, and health behaviors to better explain the observed differences and improve oral health for migrant populations.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S126-S134"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of the periodontal status in Germany: results of the 6th German Oral Health Study (DMS • 6).","authors":"Peter Eickholz, Birte Holtfreter, Kathrin Kuhr, Bettina Dannewitz, A Rainer Jordan, Thomas Kocher","doi":"10.3290/j.qi.b5981979","DOIUrl":"https://doi.org/10.3290/j.qi.b5981979","url":null,"abstract":"<p><strong>Objectives: </strong>The 6th German Oral Health Study (DMS • 6) reports on the periodontal status in population-based cohorts of younger adults (35- to 44-year-olds) and younger seniors (65- to 74-year-olds).</p><p><strong>Method and materials: </strong>Participants answered questionnaires regarding oral health behavior, and general and oral health status. Probing depth (PD), clinical attachment level (CAL), and bleeding on probing (BOP) were measured on all teeth except third molars. Number of teeth, BOP, mean PD, mean CAL, the stages of the 2018 classification of periodontal diseases, the prevalence of Community Periodontal Index (CPI), and the Centers for Disease Control and Prevention (CDC)/ American Academy of Periodontology (AAP) case definition were reported.</p><p><strong>Results: </strong>In total, 9.2%/20.6% of younger adults/younger seniors had a low education status, 25.6%/14.1% of younger adults/younger seniors were current smokers, and 2.1%/15.4% of younger adults/younger seniors had type 2 diabetes. Of all younger adults/younger seniors, 24.4%/38.7% stated that they performed interdental cleaning at least daily. The mean number of teeth in dentate younger adults/younger seniors was 26.6/20.4, of which 5.6/8.3 teeth had PD ≥ 4 mm and only 0.6/1.7 teeth had PD ≥ 6 mm. The mean number of teeth with CAL ≥ 5 mm was 1.1/3.6 in younger adults/younger seniors. Mean PD in younger adults/younger seniors was 2.1 mm/ 2.6 mm; correspondingly, mean CAL was 1.1 mm/2.4 mm. A CPI score of 4 occurred in 16.2%/42.4% of younger adults/younger seniors. In total, 13.6%/26.3% of younger adults/younger seniors were classified as having stage III periodontitis, while 3.9% and 26.4% were classified as having stage IV periodontitis according to the 2018 case classification, respectively.</p><p><strong>Conclusion: </strong>The periodontitis prevalence according to the 2018 classification (including all stages) was very high at 95.1%/85.2% in younger adults/younger seniors. In total, 31.6%/8.3% of younger adults/younger seniors were classified as stage I (ie, interdental CAL 1 to 2 mm), which, from a clinical point of view, appears to be a transitional phase between gingivitis and periodontitis, which can probably be managed with preventive rather than therapeutic measures. In younger adults and younger seniors, the prevalence of periodontitis in Germany is high, with severe periodontitis (stages III and IV) in 17.5%/52.7% of younger adults/younger seniors.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S40-S47"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between smoking and oral health: results of the 6th German Oral Health Study (DMS • 6).","authors":"Laura Krause, Anne Starker, Katrin Hertrampf, Nicolas Frenzel Baudisch, A Rainer Jordan, Vinay Pitchika, Kathrin Kuhr","doi":"10.3290/j.qi.b5982019","DOIUrl":"https://doi.org/10.3290/j.qi.b5982019","url":null,"abstract":"<p><strong>Objectives: </strong>Smoking is the most significant individual health risk and the leading cause of premature mortality in industrialized nations. International studies demonstrate that smoking also affects oral health adversely. This study aimed to investigate the association between smoking and oral health using population-representative data for Germany.</p><p><strong>Method and materials: </strong>The data source was the 6th German Oral Health Study (DMS • 6), conducted between 2021 and 2023. Data from a total of 2,135 individuals were included in the analyses. The distribution of sociodemographic characteristics (gender, age, education status), oral health behaviors (frequency of toothbrushing, interdental cleaning, and dental visits), and oral health-related parameters (self-assessed oral health, oral health-related quality of life, root caries, periodontitis, oral mucosal changes, and the number of teeth present) were reported separately for smoking status (daily smokers, former smokers, and never smoked). To estimate the associations between smoking status and oral health outcomes, mixed-effects regression models were employed.</p><p><strong>Results: </strong>Daily smokers exhibited worse outcomes in both self-assessed oral health parameters and clinical oral health measures compared to individuals who had never smoked. These associations persisted even after adjusting for sociodemographic factors and oral health behaviors. Similar trends were observed for former smokers compared to never smokers.</p><p><strong>Conclusion: </strong>Smoking is a well-established risk factor for poorer oral health. The findings of DMS • 6 confirm this association and are consistent with those of other national and international studies. Given the strong impact of smoking on oral health, comprehensive measures to curb smoking are essential. Evidence-based behavioral and structural preventive interventions exist to reduce tobacco consumption and promote smoking cessation. Dental offices can also contribute to tobacco prevention and cessation by providing brief counseling on the risks of smoking for both oral and general health.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S96-S103"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in periodontal status: results from the German Oral Health studies from 2005 to 2023.","authors":"Thomas Kocher, Peter Eickholz, Kathrin Kuhr, A Rainer Jordan, Dominic Sasunna, Vinay Pitchika, Birte Holtfreter","doi":"10.3290/j.qi.b5981996","DOIUrl":"https://doi.org/10.3290/j.qi.b5981996","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was twofold: firstly, to provide an overview of trends in periodontal status among younger adults aged 35 to 44 years and younger seniors aged 65 to 74 years between 2005 and 2023, based on data from the German Oral Health Studies (DMS); secondly, to quantify the extent to which observed differences in tooth count variables between consecutive studies can be attributed to differences in characteristics.</p><p><strong>Method and materials: </strong>The data from DMS IV (2005), DMS V (2014), and DMS • 6 (2023) were analyzed. The participants completed questionnaires concerning their oral health behaviors, and general and oral health. For this analysis, probing depths (PD) were calculated from three sites on 12 index teeth as a common denominator. The number of teeth, severity, and extent of PD and the Community Periodontal Index (CPI) were reported. Multivariate decomposition was employed to analyze differences by time.</p><p><strong>Results: </strong>The proportion of edentate younger seniors notably declined, from 23.2% to 5.4%, between 2005 and 2023. Similarly, the mean number of teeth for dentate younger seniors was 2.4 teeth higher in DMS • 6. While the mean PD remained 2.4 mm for younger adults and 2.8 mm for younger seniors, inconsistent patterns were observed for extent variables. In most cases, a decline of the extent variables was observed between DMS IV and DMS V, with a rebound at DMS • 6 for severe cases in younger seniors (with PD ≥ 6 mm). The proportion of younger adults and seniors with CPI scores of 0 to 2 increased considerably between DMS IV and DMS V, but rebounded at DMS • 6. Overall, the prevalence of these cases increased by approximately 10% points and 5% points, respectively. The majority of the observed reduction in the number of missing teeth (in younger adults) or the prevalence of having less than 20 teeth (in younger seniors) between DMS IV and DMS V and between DMS V and DMS • 6 were explained by an increase in the proportion of highly educated individuals, an increase in the proportion of those who have never smoked (only younger adults), an increase in the proportion of individuals using electric toothbrushes or interdental cleaning devices, and a reduction in the proportion of individuals with lifetime periodontal treatment.</p><p><strong>Conclusion: </strong>Over the last two decades, there has been a significant improvement in periodontal health in Germany, with the most notable enhancements occurring between DMS IV and DMS V. The prevalence of periodontal disease has decreased significantly in recent decades, largely due to the implementation of preventive measures. This underscores the importance of integrating preventive measures into dental practice as a public health strategy.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S48-S58"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DMS • 6: All new !","authors":"A Rainer Jordan, Jörg Wiltfang, Werner Geurtsen, Guido Heydecke","doi":"10.3290/j.qi.b6044427","DOIUrl":"https://doi.org/10.3290/j.qi.b6044427","url":null,"abstract":"","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S2-S3"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molar incisor hypomineralization: results of the 6th German Oral Health Study (DMS • 6).","authors":"Katrin Bekes, Hendrik Meyer-Lueckel, A Rainer Jordan, Kathrin Kuhr, Ulrich Schiffner","doi":"10.3290/j.qi.b5986273","DOIUrl":"https://doi.org/10.3290/j.qi.b5986273","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to determine the prevalence of molar incisor hypomineralization (MIH) in Germany. A secondary goal was to analyze a possible connection between MIH and caries, as well as to investigate the influence of MIH on oral health-related quality of life (OHRQoL).</p><p><strong>Method and materials: </strong>All younger adolescents (12-year-olds) from the 6th German Oral Health Study (DMS • 6) were examined for MIH according to the criteria of the European Academy of Paediatric Dentistry (EAPD). The caries experience and OHRQoL were also determined.</p><p><strong>Results: </strong>In total, 922 younger adolescents were included in the analysis. The prevalence of MIH was 15.3%; 63.3% of cases were mild forms; 8.2% of affected subjects had a caries experience. OHRQoL did not vary significantly between healthy and MIH-affected children.</p><p><strong>Conclusion: </strong>In Germany, every seventh child aged 12 years old suffers from MIH. These data on MIH in younger adolescents in Germany conform to data from regional studies; the prevalence is in the upper middle range in an international comparison.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S70-S74"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tooth loss and denture status: results of the 6th German Oral Health Study (DMS • 6).","authors":"Bernd Wöstmann, Stefanie Samietz, A Rainer Jordan, Kathrin Kuhr, Ina Nitschke, Helmut Stark","doi":"10.3290/j.qi.b5986257","DOIUrl":"https://doi.org/10.3290/j.qi.b5986257","url":null,"abstract":"<p><strong>Objectives: </strong>The German Oral Health Study (DMS) is a series of consecutive studies designed to assess the oral health status of adults, seniors, and children in Germany. DMS is a major program of the Institute of German Dentists (Institut der Deutschen Zahnärzte) with the aim to produce health statistics for Germany. Tooth loss, edentulism, and prosthetic care have considerable socioeconomic significance; it is the aim of this paper to report findings on these aspects.</p><p><strong>Method and materials: </strong>The survey combines interviews and clinical examinations. Previous DMS studies focused primarily on tooth loss, edentulism, and prosthetic care. In the DMS • 6 survey, the condition of removable dentures and need for adjustments were additionally recorded, as well as necessary repair measures that were grouped according to their complexity (chairside or laboratory).</p><p><strong>Results: </strong>The prevalence of edentulism decreased considerably compared to that in the Fifth German Oral Health Study (DMS V) in 2014. Among younger adults (35- to 44-year-olds), the prevalence of edentulism was negligible, with an average of 26.6 teeth present. The younger senior group (65- to 74-year-olds) had an average of 19.3 teeth; the prevalence of edentulism was 5%, which is a reduction of > 50% compared to 2014 (12.4%). Lower education status was an important prognostic factor for tooth loss. Owing to the low prevalence of edentulism in younger adults, removable dentures were not prevalent in this age group, whereas combined fixed-removable dentures were most frequently used in seniors. Regarding the type of denture, a shift towards fixed as well as implant-supported types was observed. Of the removable dentures, 50% to 60% were in a very good or good clinical condition. Problems were mainly identified with simple acrylic dentures. Nonetheless, participants' satisfaction with removable dentures was extremely high, and the dentures were used almost continuously.</p><p><strong>Conclusion: </strong>The most important finding in this study is the continued significant decline in the prevalence of complete edentulism among seniors that suggests a further reduction in edentulism in the future with an estimate of around 4% in 2030. The shift observed in primary prosthetic care from removable to fixed prostheses as well as the increasing prevalence of implants placed are positive developments. The data revealed further compression of morbidity compared to DMS V. Complete edentulism declined, and fixed partial dentures, including implant-supported prostheses, were increasingly used. Lower education status was an important predictor for tooth loss.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S60-S68"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the efficacy of nonsurgical periodontal treatment on rheumatoid arthritis: an umbrella review.","authors":"Xuyan Sheng, Xinjian Ye, Hefei Yuan, Changbo Zheng, Tao Zheng, Qianming Chen, Shuli Deng","doi":"10.3290/j.qi.b6043843","DOIUrl":"https://doi.org/10.3290/j.qi.b6043843","url":null,"abstract":"<p><strong>Background: </strong>The relationship between periodontitis and rheumatoid arthritis (RA) has attracted considerable interest. However, the effect of non-surgical periodontal treatment (NSPT) on RA remains uncertain. This umbrella review aims to consolidate current research to establish a stronger evidence base.</p><p><strong>Methods: </strong>Medline, Embase, and the Cochrane library were searched from inception to August 2024. Two independent reviewers handled study selection, data extraction, and quality assessment (AMSTAR-2). The qualitative analysis covered clinical activity, joint symptoms, inflammatory markers, cytokines, and autoantibodies. Quantitative results for disease activity score 28 (DAS28), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were reported as mean differences (MD)with 95% confidence intervals (CI).</p><p><strong>Results: </strong>A total of 2,982 records were screened, with 41 full-text articles assessed for eligibility, and9 selected for evidence synthesis. Qualitative analysis suggests that NSPT may reduce clinical activityin patients with periodontitis and RA. Quantitative analysis provided suggestive evidence on theeffects of NSPT on DAS28, with the MD ranging from -0.38 (95% CI: -0.46 to -0.31) to -1.18 (95%CI: -1.43 to -0.93). One-third of the included studies were rated as &#34;high&#34; quality, while another one-third were &#34;critically low&#34;.</p><p><strong>Conclusions: </strong>The present evidence suggests that NSPT may provide benefits in managing RAsymptoms in patients with periodontitis; however, the potential bias of current evidence calls forfurther rigorous studies. Clinicians should account for the complex interplay between periodontitis andRA when devising treatment strategies.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Honey in orabase paste and triamcinolone acetonide for the treatment of atrophic/erosive oral lichen planus: a randomized, blind, controlled, clinical trial.","authors":"Sally Abd El-Meniem El-Haddad","doi":"10.3290/j.qi.b6043838","DOIUrl":"https://doi.org/10.3290/j.qi.b6043838","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the clinical efficacy of an innovative preparation; honey inorabase (50% in 1:1) for treating atrophic/ erosive oral lichen planus (OLP) compared with triamcinolone acetonide 0.1% ointment.</p><p><strong>Subjects and methods: </strong>The study involved a total of 60 patients who were randomly dividedinto three groups: Group I (honey in orabase 50%, 1:1 paste), Group II (triamcinolone acetonide 0.1% ointment), and the control group, III, (orabase paste). The primary outcome measure utilized the Visual Analogue Scale (VAS), while the secondary outcome included evaluating the clinical manifestation through an OLP reduction score assessment.</p><p><strong>Results: </strong>Compared to Group III, Groups I and II experienced significant reductions in their VASand OLP scores. Participants in Groups I and II reported minimal to no discomfort, with Group I demonstrating the most substantial pain relief.</p><p><strong>Conclusion: </strong>In comparison to triamcinolone acetonide 0.1% ointment and the control group,the study showed that honey in orabase 50% paste is effective in the reduction of pain and lesion size in patients with atrophic/erosive OLP. Therefore, as an alternative to utilizing the traditional triamcinolone acetonide 0.1% ointment to treat atrophic/erosive OLP, honey in orabase 50% paste may be an effective treatment option.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergies in dentistry and potential cofactors: a case-control study.","authors":"Lisa Corvin, Sandra Freitag-Wolf, Christof Dörfer, Guido Heine","doi":"10.3290/j.qi.b5907068","DOIUrl":"10.3290/j.qi.b5907068","url":null,"abstract":"<p><strong>Objective: </strong>Allergic reactions during dental procedures are suspected frequently. Still, data on the confirmed allergens are rare. This study aimed to identify allergens in dentistry and potential cofactors in sensitization.</p><p><strong>Method and materials: </strong>Patients with suspected allergic reactions in the context of dental (study group) or surgical (control group) procedures were analyzed in a monocentric 3-year retrospective and 2-year prospective file chart analysis between 2018 and 2023. Descriptive statistics and multiple logistic regression analysis were performed.</p><p><strong>Results: </strong>In total, 129 patients were allocated to the study group and 123 to the control group. Confirmed allergy was less frequent in the study group (10%) than in the control group (28%, P .001). Local anesthetics triggered most dental reactions, but were rarely confirmed allergic (1 of 55 cases). Dental materials and implant material in the control group were confirmed in 16% and 15% of clinically relevant sensitizations, respectively. Multiple logistic regression identified reactions to local anesthetics or dental materials/implant material with a 33.33- or 2.63-fold lower risk of sensitization. A concomitant immune disease was associated with higher risk for a confirmed allergic reaction in dentistry in the cohort (OR 9.12, 95% CI 2.40 to 35.10).</p><p><strong>Conclusion: </strong>Allergy to dentally administered drugs is rare. Most local anesthetic-triggered reactions were unspecific. Reactions to dental materials resulting in objective symptoms require allergy diagnostics. (Quintessence Int 2025;56:162-170; doi: 10.3290/j.qi.b5907068).</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"162-170"},"PeriodicalIF":1.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142922753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}