Honey in orabase and triamcinolone acetonide for the treatment of atrophic/erosive oral lichen planus: a randomized, blind, controlled, clinical trial.
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引用次数: 0
Abstract
Objective: This study aimed to evaluate the clinical efficacy of an innovative preparation, honey in orabase (50% in 1:1), for treating atrophic/erosive oral lichen planus compared with triamcinolone acetonide 0.1% ointment.
Method and materials: The study involved a total of 60 patients who were randomly divided into three groups: Group I (honey in orabase 50%, 1:1 paste), Group II (triamcinolone acetonide 0.1% ointment), and the control group, Group III (orabase paste). The primary outcome measure was pain, measured on a visual analog scale, and the secondary outcome was the evaluation of the clinical manifestation through an oral lichen planus reduction score assessment.
Results: Compared to Group III, Groups I and II experienced significant reductions in their pain visual analog scale scores and oral lichen planus scores. Participants in Groups I and II reported minimal to no discomfort, with Group I demonstrating the most substantial pain relief.
Conclusion: In comparison to triamcinolone acetonide 0.1% ointment and the control group, the study showed that honey in orabase 50% paste is effective in the reduction of pain and lesion size in patients with atrophic/erosive oral lichen planus. Therefore, as an alternative to utilizing the traditional triamcinolone acetonide 0.1% ointment to treat atrophic/erosive oral lichen planus, honey in orabase 50% paste may be an effective treatment option.
期刊介绍:
QI has a new contemporary design but continues its time-honored tradition of serving the needs of the general practitioner with clinically relevant articles that are scientifically based. Dr Eli Eliav and his editorial board are dedicated to practitioners worldwide through the presentation of high-level research, useful clinical procedures, and educational short case reports and clinical notes. Rigorous but timely manuscript review is the first order of business in their quest to publish a high-quality selection of articles in the multiple specialties and disciplines that encompass dentistry.