Quintessence international最新文献

{"title":"3D virtual patient creation with intraoral and facial scanning for zirconia veneers fabrication.","authors":"Francisco Garcia-Torres, Carlos A Jurado, Silvia Rojas-Rueda, Franciele Floriani, Eric Sanchez-Alonso, Abdulrahman Alshabib","doi":"10.3290/j.qi.b6628521","DOIUrl":"https://doi.org/10.3290/j.qi.b6628521","url":null,"abstract":"<p><strong>Objectives: </strong>This clinical case report describes the application of a fully digital workflow for the esthetic and functional rehabilitation of a patient presenting severe fluorosis, internal discoloration, and previously inadequate restorations, utilizing multilayered zirconia prostheses.</p><p><strong>Materials and methods: </strong>The case integrated intraoral scanning, facial scanning, digital articulators, and CAD/CAM technology to improve treatment accuracy, predictability, and patient-specific adaptation. Initial intraoral and facial scans established functional and esthetic parameters. Occlusal adjustments were performed digitally, simulating condylar movements to ensure optimal occlusal harmony. Digital wax-ups and prototype restorations guided minimally invasive tooth preparations. Multilayered zirconia was selected due to its esthetic qualities, strength, and ability to mimic natural tooth translucency. Restorations were digitally designed, milled, verified intraorally, and bonded under rubber dam isolation.</p><p><strong>Results: </strong>The digital approach enabled precise occlusal adjustments and substantial esthetic improvements, resulting in enhanced function and natural appearance. Post-treatment assessment revealed improved color stability, optimal marginal adaptation, and high patient satisfaction. The patient was scheduled for regular three-month follow-ups and provided with an occlusal guard to ensure prosthetic longevity.</p><p><strong>Conclusion: </strong>This report highlights the clinical effectiveness of digital workflows in complex rehabilitations, underscoring benefits such as improved esthetic predictability, functional integration, and durability. Incorporating digital articulators and facial scans notably enhanced treatment precision. Multilayered zirconia restorations demonstrated superior esthetics and function, representing an effective treatment option for patients with severe discoloration and functional impairment.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of peri-implant health across different types of implantsupported prostheses and anatomical locations: a cross-sectional observational study.","authors":"Sarah B Hoerler, Whitnee R Murray, Miao Xian Zhou","doi":"10.3290/j.qi.b6628523","DOIUrl":"https://doi.org/10.3290/j.qi.b6628523","url":null,"abstract":"<p><strong>Background: </strong>Several patient and implant level factors influence the success of dental implants. This study aims to evaluate the clinical outcomes of peri-implant soft tissue across several types of implant-supported prostheses and anatomic locations at the implant level.</p><p><strong>Methods: </strong>This cross-sectional observational study included a purposive sample of adult patients with at least one dental implant and a variety of implant-supported prosthesis types over a 3-month period. Clinical assessments conducted for each implant included bleeding on probing, presence of suppuration, and implant probing depth. The data analyzed the relationship between the implant-supported prosthesis type and anatomic location on the peri-implant clinical outcomes.</p><p><strong>Results: </strong>Evaluated in this study were 134 participants with 456 implants distributed between the mandible (44%) and maxilla (56%) and the posterior (67%) and the anterior (33%). The clinical assessment revealed that implants with probing depths of 6 millimeters or greater had a significantly higher risk of suppuration compared to those with probing depths of 5 millimeters or less (P < .001). Full arch implant-supported fixed dental prostheses were associated with higher rates of bleeding on probing and suppuration compared to single tooth implants (P < .001). Anterior implants showed more bleeding than posterior implants (P = .02), whereas implants in the maxilla exhibited less bleeding than those in the mandible (P = .003).</p><p><strong>Conclusion: </strong>This study highlights the impact of the type of implant-supported prosthesis and anatomic location on peri-implant health, emphasizing the need for monitoring of full arch implant-supported fixed dental prostheses, implants with probing depths ≥6 mm, and implants placed in the anterior or mandible.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of retention cavity geometry and ferrule effect in maxillary central incisors restored with anatomically shaped glass fiber post: a finite element analysis.","authors":"Burcu Özer, Sercan Sabancı, Muhittin Toman","doi":"10.3290/j.qi.b6628534","DOIUrl":"https://doi.org/10.3290/j.qi.b6628534","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the influence of two novel internal retention cavity designs and the presence of a ferrule on stress distribution in endodontically treated maxillary central incisors restored with anatomically shaped fiber posts using finite element analysis (FEA).</p><p><strong>Method and materials: </strong>The models were divided into ferrule-present and ferrule-free groups and further subdivided according to cavity configuration: no additional retention, Retention Area 1, and Retention Area 2. A static oblique load of 100 N at 45° was applied to the palatal surface, 2 mm from the incisal edge. All simulations were conducted in ANSYS under standardized boundary conditions, with dentin stresses prioritized as dentin represents the primary load-bearing structure.</p><p><strong>Results: </strong>The ferrule-free reference model showed the highest dentin stress (187.54 MPa, σ = 7.40 MPa), indicating increased fracture risk. In the absence of a ferrule, Retention Area 1 reduced peak dentin stress substantially (62.74 MPa, σ = 4.12 MPa) and produced the most uniform stress distribution, while Retention Area 2 also lowered stresses compared with the reference (σ = 5.36 MPa). In the ferrule-present groups, stresses were overall lower, confirming the ferrule's protective role; within this group, Retention Area 1 recorded the lowest dentin stress (82.18 MPa).</p><p><strong>Conclusion: </strong>The ferrule remains biomechanically critical for preserving cervical dentin. However, in cases where a ferrule cannot be achieved, retention-oriented cavity designs demonstrated potential as a clinically viable alternative, though further validation is required.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal maintenance therapy for long-term tooth preservation and adequate oral health: a narrative review and case series.","authors":"Tae H Kwon, Daliah M Salem, Liran Levin","doi":"10.3290/j.qi.b6628510","DOIUrl":"https://doi.org/10.3290/j.qi.b6628510","url":null,"abstract":"<p><p>Periodontal diseases can lead to progressive attachment loss and eventual tooth loss if untreated. Following the successful completion of active therapy, periodontal maintenance therapy (PMT) plays a vital role in preserving periodontal health by controlling inflammation and monitoring conditions. This narrative review and case series evaluates the effectiveness of PMT in preserving teeth over long-term follow-up and explores relevant literature to highlight best practices. A search of PubMed was conducted using key terms related to PMT, tooth survival, and prognosis. Articles published between January 1, 1978, and December 15, 2024, were reviewed. Inclusion criteria focused on studies written in English and evaluating PMT outcomes. Four clinical cases illustrate the role of PMT in maintaining periodontal health across different patient profiles. PMT, when combined with patient compliance and individualized interventions, is effective in preserving teeth in periodontally compromised patients. Collaborative care between general dentists and specialists further optimizes outcomes. Regular monitoring and patient education are paramount to long-term success.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental knowledge of oral prophylaxis and recommended fluoride concentration in toothpastes for children in Israel.","authors":"Ieva Avidana, Aaya Shahin, Jomana Hassan, Samer Srouji, Mervat Khoury Absawi","doi":"10.3290/j.qi.b6287918","DOIUrl":"10.3290/j.qi.b6287918","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate parents' knowledge of the Israeli Ministry of Health guidelines on basic oral health practices and appropriate toothpaste usage for different pediatric age groups.</p><p><strong>Method and materials: </strong>Anonymous questionnaires were distributed to parents attending the Pedodontics Department. The questionnaire included two sections: general questions and questions that were completed for all children in the family, categorizing them into three age groups: under 2 years, 2 to 6 years, and over 6 years.</p><p><strong>Results: </strong>A total of 242 questionnaires and 410 responses across different age groups were collected. Most respondents knew that teeth should be brushed as soon as the first tooth appears and believed that the first dental visit should be at age 2 (60.5% and 26.9%, respectively). However, only 15% of parents answered both questions correctly. Toothpaste selection was primarily based on age (46.6%), with no significant differences across age groups for correct answer (P = .130). Awareness of the recommended fluoride concentration was low (16.1%), though parents of older children showed better knowledge (P = .040). Appropriate toothpaste amounts were used in 30.2% of the cases, with the 2- to 6-year age group demonstrating the highest awareness (P .001). Only 3.7% of parents correctly answered all three toothpaste-related questions. Overall, the knowledge score for toothpaste guidelines was highest in the middle age group (31.2%, SD = 28.66, P .001).</p><p><strong>Conclusion: </strong>A minority of parents are familiar with recommended early dental care practices and correct toothpaste usage. The findings emphasize the need to improve parental awareness from the very beginning of a child's development. (Quintessence Int 2025;56:644-653; doi: 10.3290/j.qi.b6287918).</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 8","pages":"644-653"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of medication-related osteonecrosis of the jaw through the association of surgical treatment with local and systemic adjuvant therapies: a case series with follow-ups of up to 3 years.","authors":"Leonardo Faverani, Stefany Cruz, Leonardo Delanora, Izabela Delamura, Mirela Silva, João Fonseca E Santos, Tiburtino Lima Neto, Edilson Ervolino, Valdir Garcia, Leticia Theodoro, Ana Bassi","doi":"10.3290/j.qi.b6376673","DOIUrl":"10.3290/j.qi.b6376673","url":null,"abstract":"<p><p>The objective of this case series was to report the outcomes of patients diagnosed with medication-related osteonecrosis of the jaw (MRONJ) and seek a remission through surgical management associated with local and systemic adjuvant therapies. A total of 14 patients were followed for up to 3 years, of whom one had MRONJ stage 0; three with stage I; seven with stage II; and four with stage III. Twelve patients underwent conservative sequestrectomy. In seven of these cases, the surgery was guided by fluorescence, using doxycycline preoperatively to remove necrotic bone tissue more accurately. In four participants, platelet-rich fibrin membranes were positioned at the surgical site before suturing. All 14 patients were instructed to perform daily mouthwashes with 0.12% chlorhexidine, and all underwent weekly sessions of antimicrobial photodynamic therapy according to the following protocol: Pre-irradiation with methylene blue (100 μg/mL) for 60 seconds, followed by irradiation with a low-level laser (600 nm; 100 mW; 214 J/cm2; 6 J/point; 60 s/point). Other adjuvant therapies were employed, such as the prescription of a combination of pentoxifylline and tocopherol, in addition to metronidazole paste. The proposed therapies led to remission in most patients, and although some of the patients did not achieve complete remission, they showed a significant reduction in pain complaints. These results demonstrate that the protocols used in this study are promising for the management of MRONJ in different stages. As such, they offer potential for the practice of surgeons and should be the object of further clinical investigations. (Quintessence Int 2025;56:654-666; doi: 10.3290/j.qi.b6376673).</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"654-666"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontitis and Mediterranean fever: a systematic review and metaanalysis.","authors":"Iman Elahi Vahed, Mahtab Mottaghi, Nima Khamisi, Taymaz Shirinzadeh, Kimia Mosadeghi, Elina Almadi, Sepehr Salehi Omran, Rozhin Hedayatpour, Marieh Aalizadeh, Zohre Masoumi Shahr-E Babak, Mahta Malek, Mohammad Rahmanian","doi":"10.3290/j.qi.b6353965","DOIUrl":"10.3290/j.qi.b6353965","url":null,"abstract":"<p><strong>Background: </strong>Periodontitis is a severe oral health condition that damages the supporting bone and soft tissues surrounding the teeth. In recent years, it has become evident that periodontitis could increase systemic inflammatory markers. Some studies showed a potential link between periodontitis and autoinflammatory diseases, including Familial Mediterranean fever (FMF), which is a hereditary autoinflammatory condition. The current study aimed to comprehensively evaluate the association between FMF and periodontitis by analyzing clinical periodontal parameters-Plaque Index (PI), Gingival Index (GI), and Clinical Attachment Loss (CAL)-through a meta-analysis.</p><p><strong>Methods: </strong>A thorough search was conducted across different databases, including PubMed, Scopus, Web of Science, and Google Scholar, covering publications up to July 2024. Eleven studies were included, consisting of one cohort and ten case controls. Following established methods, we performed data extraction and quality assessment of the selected publications. We conducted a meta-analysis to gather the effect sizes obtained from the eligible publications.</p><p><strong>Results: </strong>The meta-analysis highlighted a statistically significant increase in PI among FMF patients compared to controls, with a pooled mean difference of 0.1833 (95% CI: 0.0012, 0.3655; p=0.0485), indicating higher plaque accumulation in FMF patients. On the other hand, CAL exhibited a non-significant mean difference of -0.0933 (95% CI: -0.2928 to 0.1062; p = 0.3596), and the GI similarly did not reach statistical significance, presenting a mean difference of 0.3223 (95% CI: -0.0713 to 0.7158; p = 0.1085).</p><p><strong>Conclusion: </strong>Our investigation underscores a potential association between FMF and periodontitis, as seen by elevated levels of PI in FMF patients. These results suggest that FMF patients experience higher levels of periodontal inflammation, emphasizing the importance of periodontal care in this population.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"604-617"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid implant-supported restorations bonded to nitride-coated titanium bases: a clinical method to address biologic, functional, and esthetic challenges in the esthetic zone.","authors":"Rafael Del Castillo, Carlo Ercoli, Rafael Valera, José Díaz Fernández, Miguel Padial-Molina, Javier Ata-Ali","doi":"10.3290/j.qi.b6353957","DOIUrl":"10.3290/j.qi.b6353957","url":null,"abstract":"<p><strong>Objective: </strong>To describe how advancements in digital technologies and materials science provide additional restorative alternatives and material combinations for single- and multiple-unit implant-supported restorations, such as those incorporating the clinical use of nitride-coated titanium bases in combination with the two-piece, CAD/CAM, screw-retained, zirconia-ceramic, hybrid implant-supported restoration concept.</p><p><strong>Case presentation: </strong>Two partially edentulous patients with missing teeth in the maxillary esthetic zone were treated with a novel technical and restorative concept using the two-piece CAD/CAM screw-retained zirconia-ceramic hybrid-abutment crown concept bonded to nitride-coated titanium bases. Biologic outcomes showed that tissues were maintained healthy with the patients showing an adequate oral hygiene level, no detectable plaque present upon probing, and no bleeding on probing. Esthetic evaluation demonstrated an excellent esthetic outcome and peri-implant soft-tissue integration with adjacent natural teeth and pontic tissue areas, together with posttreatment stability of the gingival zenith position. Neither of the two patients showed technical complications such as screw loosening or porcelain chipping/fracture. Radiographic evaluation revealed a precise fit between nitride-coated titanium bases and the implant connecting interfaces, no marginal bone loss, and stable implant osseointegration. The principal advantages of incorporating nitride-coated titanium bases in implant-supported restorations rely on the favorable esthetic outcomes, improved technical, mechanical, and biologic aspects, as well as the physicochemical characteristics of nitride-coated titanium bases' hard thin film coatings and their positive impact on titanium biocompatibility.</p><p><strong>Conclusions: </strong>The short-term promising clinical outcomes of the two-piece CAD/CAM screw-retained, zirconia-ceramic hybrid-abutment crown concept bonded to nitride-coated titanium bases, indicate the potential clinical benefits of the described restorative alternative. However, additional in vitro investigations and randomized clinical trials are needed to validate these initial observations, especially those evaluating the two-piece CAD/CAM screw-retained, zirconia-ceramic hybrid-abutment crown bonded to nitride-coated titanium bases when compared to the conventional two-piece hybrid design as well as stock/custom, metal/zirconia/lithium disilicate, screw/cemented implant-supported restorations.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"628-642"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification of postoperative bleeding severity by general dental practitioners in the National Dental Practice-Based Research Network: a survey-based assessment.","authors":"Sharon Elad, Greg Connolly, Rita Cacciato, Rebekah Boy, Michael C Leo, William Calnon, Suzanne Gillespie, Denis Nyongesa, Gregg Gilbert, Cyril Meyerowitz","doi":"10.3290/j.qi.b6376527","DOIUrl":"10.3290/j.qi.b6376527","url":null,"abstract":"<p><strong>Objective: </strong>The objectives of this study were to: (1) describe how general dental practitioners (GDPs) in the National Dental Practice-Based Research Network ('Network') classify the severity of postoperative bleeding; and (2) examine the association between bleeding severity classification and whether the GDP had residency training.</p><p><strong>Method and materials: </strong>An electronic questionnaire was developed to assess GDPs' classification of bleeding severity for various scenarios following scaling or a single-tooth simple extraction, and to collect information about respondents' experience with bleeding scenarios. A total of 1,815 GDP members of the Network were invited to participate.</p><p><strong>Results: </strong>A total of 866 GDPs responded. Strong agreement (low variability) was observed for scenarios that were classified as 'severe bleeding' (94.7% to 96.8%), and lower agreement (higher variability) was observed for scenarios classified as 'moderate bleeding' (53.2% to 65.2%). The GDP's classification of bleeding severity was not correlated with training in a General Practice Residency (GPR) or Advanced Education in General Dentistry (AEGD). A minority of respondents had experience with 'major bleeding' that may lead to hemodynamic emergency (15.5%) or a referral to an emergency department (4.8%).</p><p><strong>Conclusion: </strong>This study identified scenarios for which there is high agreement and low agreement regarding bleeding severity classification among GDPs in the US. A small percentage of respondents had actual experience with major bleeding in their patients. Based on these results, a new tool is proposed to assess the severity of oral bleeding, intended to foster better communication between dental professionals. The new tool may assist GDPs to standardize documentation and communication with other health care professionals. (Quintessence Int 2025;56:668-679; doi: 10.3290/j.qi.b6376527).</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"668-679"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12326511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Take a step on the right track.","authors":"Yehuda Zadik, Shlomo P Zusman","doi":"10.3290/j.qi.b6574235","DOIUrl":"10.3290/j.qi.b6574235","url":null,"abstract":"","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 8","pages":"600-601"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}