Quintessence international最新文献

{"title":"Influence of edentulous span length on complete-arch intraoral scanner accuracy: a comparative in vitro study.","authors":"Yaniv Mayer, Yarden Berg, Or Kfir, Alessio Triestino, Zvi Gutmacher, Luigi Canullo","doi":"10.3290/j.qi.b639465","DOIUrl":"10.3290/j.qi.b639465","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the influence of edentulous span length on the accuracy of two intraoral scanner (IOS) devices Primescan (Dentsply Sirona) and Trios 3 (3Shape) in complete-arch scenarios. The hypothesis was that accuracy would decline with increasing span length, with performance differences between scanners.</p><p><strong>Method and materials: </strong>An in vitro study was conducted using a maxillary complete-arch model with a central incisor implant. Twelve span-length scenarios (FA1 to FA12) were created by sequentially removing adjacent teeth. Each condition was scanned 10 times using both IOS devices (n = 240). A laboratory scanner (Identica blue, Medit) provided reference scans. Trueness (vs reference) and precision (intra-group) were evaluated using root mean square (RMS) error. Scans were aligned via automatic and local best-fit in Medit Design. Statistical analysis included two-way mixed ANOVA, repeated measures ANOVA, and linear regression with Bonferroni correction (α = .004).</p><p><strong>Results: </strong>Trios 3 demonstrated lower overall RMS values (0.296 ± 0.043 mm) than Primescan (0.338 ± 0.049 mm), with significant differences in 9 of 12 scenarios (P .001). Correlation with span length was stronger for Primescan (R2 = 0.892) than Trios 3 (R2 = 0.674). Both devices showed high reliability.</p><p><strong>Conclusions: </strong>Increasing edentulous span length negatively impacts scanner accuracy. Devices demonstrating consistent performance are preferable for reliable full-arch digital workflows. (Quintessence Int 2025;56:618-625; doi: 10.3290/j.qi.b639465).</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 8","pages":"618-625"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of low-dose naltrexone in the management of posttraumatic trigeminal neuropathic pain: a retrospective case series.","authors":"Sowmya Ananthan, Gary Heir, Olga Korczeniewska","doi":"10.3290/j.qi.b6335903","DOIUrl":"10.3290/j.qi.b6335903","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Dental practitioners provide treatment of anatomical structures innervated by the trigeminal system, such as the teeth and gingiva, which can be subject to injury even following routine and well-performed dental procedures. As a result, the dental clinician is often presented with patients with neuropathic pain or unusual sensory distortions. In addition, the dental clinician treats patients following facial and oral trauma which may result in chronic pain. Therefore, recognition of posttraumatic trigeminal neuropathic pain (PTTNP) and its management must be considered essential for the dental clinician. Painful neuropathies, including PTTNP, can present as a debilitating form of neuropathic pain that often defies treatment normally effective for other types of somatic pain disorders. Treatment of PTTNP typically involves the use of various classes of medications including antiseizure medications and tricyclic antidepressants. Many patients suffering with PTTNP may have contraindications for these medications due to comorbidities, occupational responsibilities, or medication side effects. An alternative to antiseizure medications and tricyclic antidepressants is the use of low-dose naltrexone.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Method and materials: &lt;/strong&gt;This study is a retrospective extended case series of patients with PTTNP. The records of 21 patients diagnosed with painful PTTNP at the Center for Temporomandibular Disorders and Orofacial Pain of the Rutgers School of Dental Medicine were analyzed. They met the criteria of PTTNP according to the International Classification of Orofacial Pain and were prescribed low-dose naltrexone. Though a total of 21 patients were included, 12 with all the data present were included in the final analysis. The sex distribution was equal, with six women and six men, with a combined average age of 59.33 ± 13.96 years.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Low-dose naltrexone significantly reduced the patients' report of pain using visual analog scale (VAS) 0 to 10 subjective pain ratings at the follow-up visits compared to the initial VAS. Interestingly, the small group of patients who used low-dose naltrexone in combination with serotonin norepinephrine reuptake inhibitors, demonstrated a lower average VAS score at the first follow-up visit, compared to those who took low-dose naltrexone with other medications. There were no significant side effects reported by the patients. No adverse effects of low-dose naltrexone therapy were reported. Side effects of the medication are rare and, as reported the literature, include mild abdominal distress or vivid dreams. None were reported among this group of subjects.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Based on this retrospective extended case series, low-dose naltrexone appears to be a safe and effective medication for use in chronic PTTNP. These results highlight the need for future studies to elucidate low-dose naltrexone's analgesic mechanism of action and to ","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"682-690"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of symptomatic treatment for oral emergencies in pregnant women: a retrospective cohort study.","authors":"Yanjun Diao, Jinbiao Han, Yongle Shi, Xuan Xie, Yazhou He, Lin Xue, Xian Liu, Xuefeng Zhang","doi":"10.3290/j.qi.b6546019","DOIUrl":"https://doi.org/10.3290/j.qi.b6546019","url":null,"abstract":"<p><strong>Objectives: </strong>The primary objective of this study was to investigate the safety and efficacy of symptomatic treatments - encompassing both active and conservative treatments - for oral emergencies during pregnancy on two key aspects: first, the incidence of adverse pregnancy outcomes; second, the symptom relief rates of oral emergencies during pregnancy.</p><p><strong>Method and materials: </strong>Pregnant women with oral emergencies(n=118) who visited the Emergency Department of West China Hospital of Stomatology of Sichuan University, from January 34 2024 to June 2024, were included in the study. These pregnant women received symptomatic treatment for their oral emergencies. The active treatment group (n=55) consisted of pregnant women who received invasive oral interventions, while the conservative treatment group (n=63) comprised those undergoing non-invasive interventions. Data encompassed pregnant women characteristics (age, educational attainment), clinical variables, diagnostic classifications, therapeutic interventions, symptom relief status (complete/partial/no relief) and adverse pregnancy outcomes.</p><p><strong>Results: </strong>The results of this study demonstrated that the incidence of adverse pregnancy outcomes following symptomatic treatment for oral emergencies during pregnancy was 4.24% (5/118). Although a significantly lower incidence of adverse pregnancy outcomes was observed in this study (4.24%) compared to the general population (p<0.001), the statistical power of this finding remains limited Following symptomatic treatment for oral emergencies, 78.81% (93/118) of pregnant women achieved complete or partial relief. Specifically, 78.18% (43/55) in the active treatment group experienced complete symptom relief, compared with 17.46% (11/63) in the conservative treatment group, and this difference was statistically significant (p<0.001).</p><p><strong>Conclusion: </strong>Within the limitations of this study, symptomatic treatment strategies (encompassing both active and conservative treatment) for oral emergencies during pregnancy were demonstrated to be safe and effective.Furthermore, active treatment demonstrated significant superiority over conservative treatment in achieving complete relief of symptoms for oral emergencies during pregnancy.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 12-month prospective randomized controlled comparative evaluation of clinical success of esthetic flexible crowns with stainless steel crowns in primary mandibular molar teeth.","authors":"Shivani Sunder, Dinesh Rao, Sunil Panwar","doi":"10.3290/j.qi.b6541886","DOIUrl":"https://doi.org/10.3290/j.qi.b6541886","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical success of esthetic flexible crowns with stainless steel crowns in primary molars over 12 months.</p><p><strong>Methods and materials: </strong>In this randomized split-mouth pilot study, 30 children each received one SSC and one esthetic flexible crown. Clinical parameters were evaluated using modified USPHS Ryge criteria at baseline, one week, one month, three months, six months, and twelve months. Procedural time was recorded, and parental satisfaction was assessed at twelve months.</p><p><strong>Results: </strong>Based on Ryge criteria, SSCs showed significantly better resistance to staining and superior surface integrity at both 6 and 12 months (p = 0.001 and p = 0.011, respectively). At 12 months, two esthetic crowns failed, while no SSC failures were recorded. None of the other evaluated clinical parameters showed statistically significant differences between the two crown types over the 12-month follow-up. The mean time required was 12.3 ± 1.53 minutes for SSCs and 10.32 ± 1.48 minutes for esthetic crowns (p < 0.001). However, this approximately two-minute difference was not clinically significant. Parental preference favored esthetic crowns for appearance.</p><p><strong>Conclusion: </strong>SSCs outperformed esthetic flexible crowns in key clinical parameters, and failures occurred only in esthetic crowns. While parental preference for esthetics was high, these findings suggest esthetic crowns may have higher failure rates. This pilot study highlights the need for larger, long-term trials to further assess their clinical performance.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shifting definitions in dentistry: a source of clinical confusion.","authors":"Jens Christoph Türp, Güzin Neda Hasanoğlu Erbaşar","doi":"10.3290/j.qi.b6541896","DOIUrl":"10.3290/j.qi.b6541896","url":null,"abstract":"","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of amniotic membrane and collagen membrane in conjunction with coronally advanced flap for the treatment of gingival recession: a randomized controlled trial.","authors":"Mejalla Muthiah Amaladhas, Priyanka Pampani, Magesh Kumar Shekar, Kalaiselvan Dharani, Kowsalya Nallathambi, Ebenezer Mani","doi":"10.3290/j.qi.b6541904","DOIUrl":"https://doi.org/10.3290/j.qi.b6541904","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to compare the clinical efficacy of amniotic membrane (AM) and collagen membrane (CM), both used in conjunction with coronally advanced flaps (CAF), in the treatment of gingival recession, assessing their ability to achieve root coverage and improve periodontal health. The primary outcome measure was the percentage of root coverage. Secondary outcomes included recession height (RH), recession width (RW), width of keratinized tissue (WKT), probing depth (PD), and clinical attachment level (CAL).</p><p><strong>Materials and methods: </strong>A randomized controlled clinical trial was conducted involving 15 patients with bilateral gingival recessions, resulting in 30 recession sites. Each patient was assigned one control site (CAF + CM) and one test site (CAF + AM) using a coin toss for randomization. The primary outcome measure was the percentage of root coverage. Additional clinical parameters including recession height (RH), recession width (RW), width of keratinized tissue (WKT), probing depth (PD), and clinical attachment level (CAL) were recorded using a customized stent. Postoperative evaluations were performed at three months.</p><p><strong>Results: </strong>Both groups demonstrated significant improvements in RH, RW, WKT, PD, and CAL from baseline to 3 months (p < 0.001). At the 3-month follow-up, the test group (CAF + AM) achieved a mean RH reduction of 2.7 ± 0.8 mm and a mean RW reduction of 3.6 ± 1.2 mm, while the control group (CAF + CM) achieved reductions of 2.7 ± 1.0 mm and 3.7 ± 1.0 mm, respectively. The mean percentage of root coverage was 91% in the test group and 88% in the control group, with no statistically significant differences between groups (p > 0.05).</p><p><strong>Conclusion: </strong>Both AM and CM, when used in combination with CAF, are effective in managing gingival recession, yielding comparable root coverage and periodontal improvements. The study is limited by its short follow-up period and lack of histologic assessment. However, AM may offer practical advantages such as easier handling, reduced patient morbidity, and cost-effectiveness.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of provincial legislation on oral health in long-term care facilities.","authors":"Yushi Chen, Rafael Figueiredo, Lynn Petryk, Liran Levin","doi":"10.3290/j.qi.b6541914","DOIUrl":"10.3290/j.qi.b6541914","url":null,"abstract":"<p><p>In Alberta, a provincial daily oral hygiene policy (OHP) for Long-Term Care Facilities (LTCF) was approved in 2018, and a mouth care training program (MCTP) was implemented in 2015. These initiatives require LTCFs to provide residents with twice-daily oral hygiene assistance and staff training. This study aimed to evaluate the provincial implementation scope, compliance rates, perceived impact on residents, and areas for improvement. A web-based survey was distributed to LTCF managers across Alberta, with 77 responses representing 11,653 residents. Overall, 66.2% of LTCF managers had implemented the OHP, and 50.6% implemented the MCTP. Managers implementing these policies showed a 14.3% increase in twice-daily oral hygiene provision, with 46% reporting improved oral cleanliness. Notably, 33.9% indicated improved resident quality of life, and 55.2% observed increased staff oral health knowledge. However, reliance on family/caregivers for oral hygiene products (79.2%) and poor attendance at external dental appointments (67.6%) were significant barriers reported by managers. Thus, while policy implementation has positively impacted residents and staff, gaps remain in resource availability and professional support. Future policies should focus on enhancing access to oral health professionals and providing in-house dental resources.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 10-year clinical review of submandibular triangle masses.","authors":"Yu Wu, Zhiying He, Donghai Huang","doi":"10.3290/j.qi.b6496130","DOIUrl":"10.3290/j.qi.b6496130","url":null,"abstract":"<p><strong>Objectives: </strong>This study addresses the gap in retrospective analyses concerning submandibular triangle masses, utilizing a large Chinese cohort, to provide experience for preoperative diagnosis and a basis for individualized treatment.</p><p><strong>Methods: </strong>We collected basic demographic information, medical histories, physical examination findings, imaging results, and histopathological diagnoses for 608 patients who underwent surgical procedures in the submandibular triangle at Xiangya Hospital, Central South University, from January 2009 to June 2019. Statistical analyses were conducted to identify differences between malignant and benign masses, employing both univariate and multivariate analyses.</p><p><strong>Results: </strong>The cohort comprised 405 males and 203 females, with an average age of 43.17 ± 19.6 years (range 1 to 80 years). The prevalence of congenital masses, inflammatory masses, and tumors were 2.6%, 63.5%, and 33.9%, respectively. Among the identified tumors, benign, borderline, and malignant tumors represented 48.4%, 1.6%, and 50.0%, respectively. Pleomorphic adenoma and lymphoma emerged as the most frequent benign and malignant pathologies, respectively, with metastatic tumors primarily originating from head and neck cancers. Univariate analysis revealed significant differences based on gender, age, smoking status, alcohol consumption, betel nut chewing habits, mass characteristics (mobility and texture), and the presence of cervical lymph nodes. Multivariate analysis identified age, alcohol consumption, and betel nut chewing as significant risk factors for malignancy.</p><p><strong>Conclusion: </strong>A comprehensive analysis of clinical parameters aids in the preoperative diagnosis of submandibular triangle masses.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of appliance therapy on orofacial muscle activity in mouth breathers: an electromyographic study.","authors":"Madhulika Srivastava, Priyanka, Subash Singh, Rashika Singhania","doi":"10.3290/j.qi.b6496142","DOIUrl":"10.3290/j.qi.b6496142","url":null,"abstract":"<p><strong>Objectives: </strong>Mouth breathing is a condition that alters normal skeletal and dental development while also affecting the surrounding orofacial muscles. Electromyography (EMG) provides an objective method to assess these muscular changes. This study aimed to evaluate the activity of the buccinator, orbicularis oris, mentalis, sternocleidomastoid, and trapezius muscles in mouth breathers before and after interceptive therapy and compare these findings with those of nasal breathers.</p><p><strong>Method and materials: </strong>Children aged 6 to 12 years were selected based on inclusion/exclusion criteria and categorized into two groups: Group I (mouth breathers, n=18) and Group II (nasal breathers, n=18). The electromyographic activity of all the five selected muscles were recorded at rest and during maximal contraction using an EMG Retrainer (Chattanooga Group Inc, DJO UK Ltd, Guildford Surrey, GU2 8XG United Kingdom), an intraoral device used to measure muscle activity, particularly in the orofacial region. Statistical analysis was performed using SPSS version 22.0, with significance set at p<0.05. The Mann-Whitney U test was used for intergroup and intragroup comparisons.</p><p><strong>Results: </strong>Results showed significant differences in muscle activity before and after appliance therapy, particularly in the buccinator, mentalis, orbicularis oris, trapezius, and sternocleidomastoid muscles. Post-therapy, the orbicularis oris and buccinator muscles exhibited notable differences in mouth breathers.</p><p><strong>Conclusion: </strong>Surface EMG can be a valuable diagnostic and biofeedback tool in pediatric interceptive orthodontics, aiding in treatment assessment and relapse prevention.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frostbite injuries to the head and neck associated with nitrous oxide abuse: review of published cases.","authors":"John K Brooks","doi":"10.3290/j.qi.b6444238","DOIUrl":"https://doi.org/10.3290/j.qi.b6444238","url":null,"abstract":"<p><strong>Objectives: </strong>The objectives of this article were to provide a review of published cases of frostbite injuries of the head and neck associated with abuse of nitrous oxide (NO) abuse and summarize other the pathophysiologic consequences.</p><p><strong>Methods and materials: </strong>A literature search was undertaken for articles on the development of frostbite injuries to the head and neck from recreational use of NO, including review papers, clinical investigations, case reports, case series, cohort studies, and letters to the editor. Relevant articles were ascertained from the electronic databases of PubMed and Google Scholar from extending January 1, 1985 through July 5, 2025 and from references cited within culled sources.</p><p><strong>Results: </strong>The search identified 13 articles, involving 16 patients, with NO-related frostbite injuries to the head and neck. Commonly affected sites included the face, lips, oropharynx, and palate. Six patients required hospital admission, including 3 who were referred to the intensive care unit.</p><p><strong>Conclusions: </strong>Oral healthcare practitioners should be aware of contemporary modalities of substance abuse, particularly from recreational use of NO and consequent risk of frostbite to the mucocutaneous structures of the head and neck. Attending clinicians are advised to educate their patients about the potential for these injuries from recreational NO abuse.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"0"},"PeriodicalIF":1.5,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}