Quintessence international最新文献

{"title":"Long-term preservation and maintenance of periodontally compromised teeth: a narrative literature review, recommended approach, and case series.","authors":"Daliah M Salem, Tae H Kwon, Abdulmonem Alshihri, Liran Levin","doi":"10.3290/j.qi.b6046543","DOIUrl":"10.3290/j.qi.b6046543","url":null,"abstract":"<p><p>There is a plethora of studies reporting successful long-term retention of periodontally compromised teeth. However, such teeth are more likely to be extracted during active therapy than during supportive periodontal therapy. With the vastly growing dental implant market, the inclination to extract periodontally compromised teeth has become more pronounced. In this narrative review, relevant literature along with suggested guidelines for dental partitioners are presented, as well as four cases, in which teeth with compromised periodontal prognosis were successfully managed, with follow-ups of up to 36 years. Conclusion: Preserving periodontally compromised teeth should be highly considered, especially because they tend to outlast dental practitioners' expectations as well as the implant alternatives. The decision to replace periodontally compromised teeth with implants should be taken with caution as there is increased evidence that the success rates of implants in treated periodontal disease patients are lower than in patients without the history of periodontitis. Furthermore, there are significantly lower overall costs of treating and maintaining stage III and IV periodontitis-affected teeth with periodontal regeneration than placing and maintaining implants in the long term.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 3","pages":"178-185"},"PeriodicalIF":1.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant, antibacterial, and systemic efficacy of sesame oil pulling in periodontitis and diabetes management.","authors":"Nehil Saran, Rameshwari Singhal, Abbas Ali Mahdi, Deepak Bhaghchandani, Pavitra Rastogi, Nand Lal, Shivani Pandey, Supriya Bhalerao","doi":"10.3290/j.qi.b5923875","DOIUrl":"10.3290/j.qi.b5923875","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of sesame oil pulling in periodontitis with/without type 2 diabetes mellitus (T2DM), compared to chlorhexidine, for its oral and systemic health benefits.</p><p><strong>Method and materials: </strong>A total of 120 periodontitis patients, without (Group A; 60)/with (Group B; 60) T2DM, underwent control (chlorhexidine 0.12%; Group A1 and B1) and test (sesame oil pulling; Group A2 and B2) interventions. Plaque index, pocket depth, salivary total antioxidant capacity (T-AOC) enzyme-linked-immunosorbent-assay (ELISA), subgingival plaque BANA test, and serum C-reactive protein (CRP) were evaluated at baseline and 30 days post-intervention using analysis of variance (ANOVA) with a significant P value set at .05. Group B serum samples were also analyzed for fructosamine and lipid profile.</p><p><strong>Results: </strong>Both treatment regimens were equivalent in reduction of plaque, pocket depth, and red complex periodontopathogens in Group A and B. Significant increase in salivary T-AOC post-intervention was observed in Group B with both interventions (P .01). Sesame oil pulling significantly decreased systemic CRP and triglyceride levels, with no difference observed with chlorhexidine in Group B.</p><p><strong>Conclusion: </strong>Sesame oil pulling is equivalent to chlorhexidine for anti-plaque, antibacterial, and antioxidant effects in periodontitis patients with/without T2DM. Systemic anti-inflammatory, cardio-protective benefits (reduction of CRP and triglycerides) make it a better adjunct to scaling and root planing than chlorhexidine in periodontitis with T2DM.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"198-205"},"PeriodicalIF":1.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and comparison of temporomandibular disorders according to Axis I in RDC/TMD and DC/TMD: a cross-sectional study.","authors":"Merve Cakir, Gül Merve Yalcin Ülker, Özgür Erdogan","doi":"10.3290/j.qi.b5938256","DOIUrl":"10.3290/j.qi.b5938256","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the prevalence of different temporomandibular disorder (TMD) diagnoses according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) and to compare the diagnoses according to both guidelines.</p><p><strong>Method and materials: </strong>Clinical examinations of 218 patients with TMD complaints were conducted according to both guidelines. Descriptive statistics were performed to analyze the frequency of diagnoses and differences between the guidelines.</p><p><strong>Results: </strong>Most patients diagnosed with TMD were women and middle-aged. The number of patients in the myofascial pain class was significantly lower for the RDC/TMD classification than for the DC/TMD classification (P = .045). The number of patients in the disc displacement with reduction category was significantly higher for the RDC/TMD classification than for the DC/TMD classification (P .001). Other categories did not exhibit differences between the classifications.</p><p><strong>Conclusion: </strong>Women and middle-aged individuals are more affected by TMDs. Pain-related TMDs were the most common diagnosis, followed by disc displacement with reduction according to DC/TMD. According to the RDC/TMD classification, myofascial pain, arthralgia, and disc displacement with reduction were the most commonly observed diagnoses, respectively. Significant differences were observed between the pain-related TMD and disc displacement with reduction groups.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"238-247"},"PeriodicalIF":1.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis' effects on dental implants osseointegration and survival rate: a systematic review of clinical studies.","authors":"Jamil A Shibli, Viviane Naddeo, Khalila C Cotrim, Eduardo C Kalil, Erica Dorigatti de Avila, Fernanda Faot, Leonardo P Faverani, João Gabriel S Souza, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes","doi":"10.3290/j.qi.b5927487","DOIUrl":"10.3290/j.qi.b5927487","url":null,"abstract":"<p><strong>Objectives: </strong>The goal of this systematic review was to critically appraise the existing evidence evaluating osteoporosis' effects on dental implant osseointegration and survival rate.</p><p><strong>Data source: </strong>A search was conducted in two databases, PubMed/MEDLINE and Scopus, until October 2024, using the keywords 'osteoporosis,' 'osteopenia,' 'osseointegration,' and 'dental implants'. The inclusion criteria were clinical studies that evaluated the implant placement, complications, and osseointegration results in patients with osteoporosis; literature reviews and clinical studies addressing the outcome were considered; and articles written in English and published since 2000. Descriptive data analysis included author, year of publication, study design, number of patients, osteoporosis assessment, follow-up, and main findings. JBI quality assessment was performed. Overall, 24 articles were included with a total of 2,102 patients; 5,954 dental implants were considered and evaluated. Most studies evaluated bone density for osteoporosis by dual-energy x-ray technology. The follow-up ranged from 1 month to 25 years. Four studies evaluated implants with over 10 years of follow-up. All studies' survival rate was higher than 90%, even for osteoporotic patients. Most studies indicated no differences between osteoporotic and healthy patients regarding marginal bone loss, bone-to-implant contact, cytokine levels, and mineral bone density. A prospective cohort study found a small marginal bone loss (-0.34 mm) in osteoporotic women, but there was insufficient evidence to prove any causal relationship between marginal bone loss and osteoporosis. Another study showed no clinical differences between implants placed in osteoporotic and healthy individuals. In contrast, other studies showed lower stability scores for implants placed in osteoporotic sites and a higher risk of failure for implant placement. Osteoporosis status was not a risk factor for dental implant failure, which was also confirmed by histologic studies. Three studies had a medium risk of bias, and 21 a low risk.</p><p><strong>Conclusion: </strong>Osteoporosis is not a contraindication for dental implant placement. Osseointegration in patients with osteoporosis is feasible; however, planning must be cautious and personalized for the placement of dental implants.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"206-216"},"PeriodicalIF":1.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse idiopathic skeletal hyperostosis (DISH): incidental radiologic finding in an older adult.","authors":"John K Brooks, Azin Parsa, Rewa O Hazim, Sylvan Feldman, Sharon L Varlotta, Jeffery B Price","doi":"10.3290/j.qi.b5966655","DOIUrl":"10.3290/j.qi.b5966655","url":null,"abstract":"<p><p>Diffuse idiopathic skeletal hyperostosis (DISH) is a somewhat uncommon osteopathic disorder associated with interconnected ossifications along the anterior vertebrae and may be accompanied by systemic comorbidities. To date, there is limited information concerning DISH in the dental literature. The objective of this report was to provide an overview of DISH for the general dental practitioner, illustrated with a case report involving an asymptomatic patient. An 87-year-old man underwent a preprosthodontic assessment, including a CBCT scan. Incidental CBCT findings included bridging ossification involving the anterior aspects of C3 and C4, resulting in mild airway displacement and mild reduction in airway volume, left calcified carotid atheroma, and bilateral intracranial carotid artery calcifications. At a 5-month follow-up telephone call, the patient admitted that he had remained asymptomatic and has not experienced dyspnea, dysphagia, throat pain, or episodic choking. Dental health care clinicians should remain vigilant for the radiologic evidence of DISH, especially involving older patients. Patients with suspected cases of DISH warrant timely referral for a comprehensive medical evaluation.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"248-253"},"PeriodicalIF":1.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing axial inclination with clear aligner orthodontic treatment to address recession defects: a case series.","authors":"Shmuel Einy, Anahat Khehra, Liran Levin","doi":"10.3290/j.qi.b5923896","DOIUrl":"10.3290/j.qi.b5923896","url":null,"abstract":"<p><p>Proper alignment of the teeth not only aids in functional occlusion but also promotes harmonious gingival contours, potentially reducing the risk of inflammation and gingival recession. This case series aimed to evaluate the effectiveness of optimizing axial inclination through clear aligner orthodontic treatment in addressing gingival recession defects. This case series included nine patients, aged 20 to 36 years, who presented with varying degrees of gingival recession on 12 mandibular incisors. All patients had undergone orthodontic treatment during childhood and were maintained with a fixed stainless-steel canine-to-canine retainer. The exhibited gingival recessions were potentially caused by inadvertent torque discrepancies in the teeth induced by the retention wire. Prior to treatment, a comprehensive radiographic and periodontal evaluation was performed, and clear aligner orthodontic treatment was used to correct the axial inclination of the affected teeth. Following the completion of the orthodontic treatment, patients were reevaluated to assess changes in recession depth and width; those with remaining recession were considered for soft tissue grafting. The average treatment duration was 21.6 ± 3.7 months, ranging from 18 to 29 months. Root torque adjustments averaged 12 ± 9 degrees, ranging from a correction of 14 degrees lingually to 33 degrees labially, while buccolingual crown movement averaged 1.7 ± 1.2 mm, with a range from 3.4 mm lingually to 0.6 mm labially. All cases showed improvement in gingival recession, with complete recovery in one tooth and an average of 58% ± 21% reduction in recession depth and width for the remaining 11 teeth. Surgical intervention, consisting of soft tissue grafting, was required in four cases, while the remaining eight teeth showed sufficient improvement and were monitored with follow-up care. Correcting axial inclination with clear aligner orthodontic treatment positively impacts both tooth alignment and gingival recession. These findings propose a new approach: initiating orthodontic treatment before periodontal surgery to streamline treatment and reduce the need for invasive procedures. Orthodontists, general dental practitioners, and patients should be aware of the potential complications of fixed retainers and their possible orthodontic adjustments correction.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"0 0","pages":"218-225"},"PeriodicalIF":1.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health in the elderly: results of the 6th German Oral Health Study (DMS • 6).","authors":"Stefanie Samietz, Bernd Wöstmann, Kathrin Kuhr, A Rainer Jordan, Helmut Stark, Ina Nitschke","doi":"10.3290/j.qi.b5982021","DOIUrl":"10.3290/j.qi.b5982021","url":null,"abstract":"<p><strong>Objectives: </strong>Oral health plays a central role in overall well-being, including in the elderly. The demographic transition and its effects are resulting in a higher proportion of older people, both with and without care requirements. This paper provides an overview of the dental situation of the elderly from the 6th German Oral Health Study (DMS • 6).</p><p><strong>Method and materials: </strong>DMS • 6 is a population-representative oral epidemiologic study that surveys oral health in Germany. Data from 797 younger seniors aged 65 to 74 were collected by calibrated examiners. The methodology remains largely consistent with that of the previous studies.</p><p><strong>Results: </strong>Among the younger seniors (65- to 74-year-olds), edentulism has more than halved to 5.0% compared to the Fifth German Oral Health Study (DMS V) (12.4% in 2014). The mean number of missing teeth (8.6) decreased further, compared to DMS IV (14.1) and DMS V (11.1). At 18.8 teeth, the FST Index (number of filled or sound teeth) has shown improvement compared to the previous studies (DMS IV, 13.6; DMS V, 16.4). The root caries (59.1%) increased compared to DMS IV (28.0%). Caries experience (decayed, missing, filled teeth [DMFT]: 17.6), in contrast, hardly changed from DMS V (17.7). Half of 65- to 74-year-olds were diagnosed with moderate periodontitis (49.4%) and almost a third (30.4%) with severe periodontitis. In younger seniors with care requirements, therapeutic capability was greatly reduced for almost half (47.4%) and oral hygiene ability for one fifth (18.5%).</p><p><strong>Conclusion: </strong>The prevalence of tooth loss and edentulism among younger seniors in Germany continues to decline. Due to further morbidity compression, the challenges of dental treatment lie in the continuous treatment of younger seniors to prepare them for older stages of life.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S112-S119"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral hygiene behavior and toothbrushing skills: results of the 6th German Oral Health Study (DMS • 6).","authors":"Renate Deinzer, A Rainer Jordan, Kathrin Kuhr, Jutta Margraf-Stiksrud","doi":"10.3290/j.qi.b5982011","DOIUrl":"10.3290/j.qi.b5982011","url":null,"abstract":"<p><strong>Objectives: </strong>Past German Oral Health Studies (DMS) have revealed that toothbrushing patterns - a behavioral index comprising toothbrushing frequency, duration and timing - have steadily improved over the previous decades. What has not yet been investigated, however, are toothbrushing skills, ie, the ability to achieve oral cleanliness by removing all plaque deposits.</p><p><strong>Method and materials: </strong>All participants of the DMS • 6 from the age groups of 12-year-olds, 35- to 44-year-olds, and 65- to 74-year-olds were asked to brush their teeth to the best of their ability. To do so, they used their own devices or those provided. The plaque that remained after brushing was recorded using the modified Marginal Plaque Index (mMPI), expressing the percentage of segments remaining at the gingival margin that were colonized by plaque. Relationships to questionnaire data regarding demographics (age, gender, education status), toothbrushing behavior (frequency, utilization of an electric toothbrush), and selected dental treatments (professional tooth cleaning, lifetime periodontal treatment) were assessed.</p><p><strong>Results: </strong>Even following the best possible brushing, roughly half of the segments (44% to 52%) across all age groups showed persisting plaque deposits. Survey data revealed the most pronounced group differences regarding education, whereby even in the group of younger seniors with a high education status, 37% of the areas showed persisting plaque after cleaning.</p><p><strong>Conclusion: </strong>The data demonstrate that there are population-wide deficits in the ability to achieve oral cleanliness. Future prevention efforts should also focus on improving the population's toothbrushing skills.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S82-S87"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular diseases and oral health: results of the 6th German Oral Health Study (DMS • 6).","authors":"A Rainer Jordan, Kathrin Kuhr, Dominic Sasunna, Wolfgang Rathmann","doi":"10.3290/j.qi.b5982020","DOIUrl":"10.3290/j.qi.b5982020","url":null,"abstract":"<p><strong>Objectives: </strong>Epidemiologic studies have indicated a correlation between dental and cardiovascular diseases, which remains insufficiently explored. Therefore, this study aimed to compare the prevalence of common dental diseases in younger seniors (65- to 74-year-olds) with and without cardiovascular diseases.</p><p><strong>Method and materials: </strong>Participants with available self-reported data on cardiovascular diseases were selected from the cohort of the population-representative 6th German Oral Health Study (DMS • 6), in which caries, periodontitis, and tooth loss were recorded in a standardized manner. The prevalence of oral diseases was compared between participants with and without cardiovascular diseases.</p><p><strong>Results: </strong>Compared with participants without cardiovascular diseases, those with cardiovascular diseases had an average of 2.1 fewer teeth, were more frequently edentulous, and were more likely to have advanced periodontal disease (stage IV). In contrast, participants without cardiovascular disease had more fillings (mean + 1.7 teeth) than those with cardiovascular disease.</p><p><strong>Conclusion: </strong>The main cause of increased tooth loss - caries or periodontal disease - could not be clarified from the available data. In this study, the prevalence of tooth loss with oral-function limitation was higher in younger seniors with cardiovascular disease.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S104-S110"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erosions in younger adults in Germany: results of the 6th German Oral Health Study (DMS • 6).","authors":"Ulrich Schiffner, A Rainer Jordan, Hendrik Meyer-Lueckel, Kathrin Kuhr, Katrin Bekes","doi":"10.3290/j.qi.b5982008","DOIUrl":"10.3290/j.qi.b5982008","url":null,"abstract":"<p><strong>Objectives: </strong>In addition to caries, other dental hard tissue diseases, such as erosive wear, are gaining importance in prevention and treatment. The survey aimed to collect current data on the prevalence of erosions in younger adults and to compare these with the previous state of knowledge.</p><p><strong>Method and materials: </strong>As part of the representative 6th German Oral Health Study (DMS • 6), all teeth were assessed according to the basic erosive wear examination (BEWE). The maximum value of the findings per sextant was included in the evaluation.</p><p><strong>Results: </strong>The prevalence of erosions was found to be 43.2%. At 49.1%, men had significantly more erosions than women (37.8%). Younger adults with a high education status were affected by erosions more frequently than persons with a medium or low education status (49.2%, 37.9%, and 45.1%, respectively).</p><p><strong>Conclusion: </strong>The prevalence of erosions remains practically unchanged from the Fifth German Oral Health Study (DMS V) of 2014. However, the proportion of people at increased risk has risen sharply. The continued high prevalence of erosions combined with the increased proportion of people with a medium or high risk classification indicates that the prevention and treatment of erosive wear is a clinically relevant issue.</p>","PeriodicalId":20831,"journal":{"name":"Quintessence international","volume":"56 11","pages":"S76-S80"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}