Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine最新文献_第6页

The effect of different mechanism combinations on sliding between brace and lower limb during walking and leg-raising. 不同的机构组合对行走和抬腿过程中支架和下肢之间滑动的影响。

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-27 DOI: 10.1177/09544119241241440

Yuzhou Yan, Ruitao Gong, Mengzhao Cao, Bing Han, Hui Li, Geng Liu

{"title":"The effect of different mechanism combinations on sliding between brace and lower limb during walking and leg-raising.","authors":"Yuzhou Yan, Ruitao Gong, Mengzhao Cao, Bing Han, Hui Li, Geng Liu","doi":"10.1177/09544119241241440","DOIUrl":"10.1177/09544119241241440","url":null,"abstract":"Knee braces are commonly used to support the knee joint and improve function. However, brace sliding caused by the misalignment between brace and knee during motion is a common problem, which reduces the therapeutic effect and leads to brace abandonment. To investigate the effect of mechanism combinations on sliding, an experimental brace was designed to isolate the mechanism as the sole variable. Ten healthy participants were recruited, each of whom worn four combinations of lateral/medial mechanisms: lateral and medial single-axis (SA), lateral super gear (SG) and medial non-circular gear (NCG), lateral four-bar linkage (FL) and medial SG, and lateral FL and medial NCG. The knee flexion angle was collected using inertial measurement units, and brace sliding was measured by 3D motion capture system. All combinations had significant changes in peak sliding of thigh and shank compared to the SA combination (p < 0.05), but lateral FL and medial NCG combination had the lowest peak and final sliding during walking and leg-raising, with significant reductions of 40.7 and 85.3% in peak sliding of thigh, and significant reductions of 56.3 and 72.0% in peak sliding of shank, respectively (p < 0.05). Moreover, the mechanism combination did not significantly impact the knee range of motion (p > 0.05). The mechanism combination that fit the instantaneous center of rotation of lateral/medial condyle of knee joint demonstrates a significant reduction in brace sliding. Additionally, the peak sliding during motion is significantly higher than the final sliding.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"500-507"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluate the effect of bone density variation on stress distribution at the bone-implant interface using numerical analysis. 利用数值分析评估骨密度变化对骨-种植体界面应力分布的影响。

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-27 DOI: 10.1177/09544119241240940

Bhargav Hindurao, Aditya Gujare, Harshavardhan Jadhav, Pankaj Dhatrak

{"title":"Evaluate the effect of bone density variation on stress distribution at the bone-implant interface using numerical analysis.","authors":"Bhargav Hindurao, Aditya Gujare, Harshavardhan Jadhav, Pankaj Dhatrak","doi":"10.1177/09544119241240940","DOIUrl":"10.1177/09544119241240940","url":null,"abstract":"The current study aims to comprehend how different bone densities affect stress distribution at the bone-implant interface. This will help understand the behaviour and help predict success rates of the implant planted in different bone densities. The process of implantation involves the removal of bone from a small portion of the jawbone to replace either a lost tooth or an infected one and an implant is inserted in the cavity made as a result. Now the extent of fixation due to osseointegration is largely dependent on the condition of the bone in terms of the density. Generally, the density of the bone is classified into four categories namely D1, D2, D3, and D4; with D1 being purely cortical and D4 having higher percentage of cancellous bordered by cortical bone. A bone model with a form closely resembling the actual bone was made using 3D CAD software and was meshed using Hyper Mesh. The model was subjected to an oblique load of 120 N at 70° to the vertical to replicate occlusal loading. A finite element static analysis was done using Abaqus software. The stress distribution contours at the bone-implant contact zone were studied closely to understand the changes as a result of the varying density. It was revealed that as the quantity of the cancellous bone increased from D1 to D4 the cortical peak stress levels dropped. The bone density and the corresponding change in the material characteristics was also responsible for the variation in the peak stress and displacement values.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"463-470"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of polydimethylsiloxane surface morphology on osteogenic differentiation of mesenchymal stem cells through SIRT1 signalling pathway. 聚二甲基硅氧烷表面形态通过 SIRT1 信号通路对间充质干细胞成骨分化的影响

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-04-01 DOI: 10.1177/09544119241242964

Zezun Hu, Fanlei Yang, Pan Xiang, Zongping Luo, Ting Liang, Hao Xu

{"title":"Effect of polydimethylsiloxane surface morphology on osteogenic differentiation of mesenchymal stem cells through SIRT1 signalling pathway.","authors":"Zezun Hu, Fanlei Yang, Pan Xiang, Zongping Luo, Ting Liang, Hao Xu","doi":"10.1177/09544119241242964","DOIUrl":"10.1177/09544119241242964","url":null,"abstract":"Constructing surface topography with a certain roughness is a widely used, non-toxic, cost-effective and effective method for improving the microenvironment of cells, promoting the proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs), and promoting the osseointegration of grafts and further improving their biocompatibility under clinical environmental conditions. SIRT1 plays an important regulatory role in the osteogenic differentiation of bone marrow-derived MSCs (BM-MSCs). However, it remains unknown whether SIRT1 plays an important regulatory role in the osteogenic differentiation of BM-MSCs with regard to surface morphology. Polydimethylsiloxane (PDMS) with different surface morphologies were prepared using different grits of sandpaper. The value for BMSCs added on different surfaces was detected by cell proliferation assays. RT-qPCR and Western blotting were performed to detect SIRT1 activation and osteogenic differentiation of MSCs. Osteogenesis of MSCs was detected by alkaline phosphatase (ALP) and alizarin red S staining. SIRT1 inhibition experiments were performed to investigate the role of SIRT1 in the osteogenic differentiation of MSCs induced by surface morphology. We found that BM-MSCs have better value and osteogenic differentiation ability on a surface with roughness of PDMS-1000M. SIRT1 showed higher gene and protein expression on a PDMS-1000M surface with a roughness of 13.741 ± 1.388 µm. The promotion of the osteogenic differentiation of MSCs on the PDMS-1000M surface was significantly decreased after inhibiting SIRT1 expression. Our study demonstrated that a surface morphology with certain roughness can activate the SIRT1 pathway of MSCs and promote the osteogenic differentiation of BMSCs via the SIRT1 pathway.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"537-549"},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140336657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physics-based in silico modelling of microvascular pulmonary perfusion in COVID-19. 基于物理的 COVID-19 微血管肺灌注硅学建模。

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-04-02 DOI: 10.1177/09544119241241550

Elizabeth Dimbath, Shea Middleton, Matthew Sean Peach, Andrew W Ju, Stephanie George, Lisandra de Castro Brás, Alex Vadati

{"title":"Physics-based in silico modelling of microvascular pulmonary perfusion in COVID-19.","authors":"Elizabeth Dimbath, Shea Middleton, Matthew Sean Peach, Andrew W Ju, Stephanie George, Lisandra de Castro Brás, Alex Vadati","doi":"10.1177/09544119241241550","DOIUrl":"10.1177/09544119241241550","url":null,"abstract":"Due to its ability to induce heterogenous, patient-specific damage in pulmonary alveoli and capillaries, COVID-19 poses challenges in defining a uniform profile to elucidate infection across all patients. Computational models that integrate changes in ventilation and perfusion with heterogeneous damage profiles offer valuable insights into the impact of COVID-19 on pulmonary health. This study aims to develop an in silico hypothesis-testing platform specifically focused on studying microvascular pulmonary perfusion in COVID-19-infected lungs. Through this platform, we explore the effects of various acinar-level pulmonary perfusion abnormalities on global lung function. Our modelling approach simulates changes in pulmonary perfusion and the resulting mismatch of ventilation and perfusion in COVID-19-afflicted lungs. Using this coupled modelling platform, we conducted multiple simulations to assess different scenarios of perfusion abnormalities in COVID-19-infected lungs. The simulation results showed an overall decrease in ventilation-perfusion (V/Q) ratio with inclusion of various types of perfusion abnormalities such as hypoperfusion with and without microangiopathy. This model serves as a foundation for comprehending and comparing the spectrum of findings associated with COVID-19 in the lung, paving the way for patient-specific modelling of microscale lung damage in emerging pulmonary pathologies like COVID-19.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"562-574"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140336658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resistance model of an active capsule endoscope in a peristaltic intestine. 主动胶囊内窥镜在蠕动肠道中的阻力模型。

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-22 DOI: 10.1177/09544119241239112

Yi Huang, Liang Liang, Puhua Tang, Zhiming Guo

引用次数: 0

Assessing patient transport conditions during ambulance transit. 评估救护车转运过程中的病人运送条件。

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-04-01 DOI: 10.1177/09544119241240908

Pedro Vitor Uchima, Sérgio Junichi Idehara

{"title":"Assessing patient transport conditions during ambulance transit.","authors":"Pedro Vitor Uchima, Sérgio Junichi Idehara","doi":"10.1177/09544119241240908","DOIUrl":"10.1177/09544119241240908","url":null,"abstract":"Emergency ambulances play a vital role in medical rescue and patient transportation, but their transit can impact patient health due to vehicle dynamic forces and vibrations. This study evaluates patient transport conditions on a stretcher subjected to vertical vibration excitation from road unevenness. Using an eight-degree-of-freedom numerical model, we analyze the construction parameters of a medical stretcher's support and vehicle suspension. Actual experimental data from an emergency vehicle were utilized to assess the vibration conditions experienced by both the stretcher and the ambulance floor. The model is adjusted based on measurements, specifically targeting the main vibration modes. The investigation involves determining temporal responses for vertical accelerations and characterizing vibration modal parameters under various transportation conditions. Notably, several system natural frequencies fall within the range of human body frequencies, making them susceptible to mechanical excitation, particularly in the human neck, abdomen, and spine. A sensitivity analysis underscores the influence of medical stretcher support structure parameters on patient comfort. Increasing support stiffness, which alters the stretcher's natural frequency, and damping coefficient reduce vibration propagation between the vehicle and the patient. Additionally, the research predicts the model's dynamic behavior on roads with low-quality pavement, indicating vibrational amplitudes that could potentially be discomforting and unhealthy for individuals. The study illustrates a vibration exposure period on a class E road, revealing that transportation longer than 25 min may cause damage to patient health.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"508-519"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140336656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phantom validation of a novel RSA-based impingement metric to assess component-on-component impingement risk. 对基于 RSA 的新型撞击度量进行模型验证，以评估组件间撞击风险。

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-22 DOI: 10.1177/09544119241238950

Shahnaz Taleb, Jordan S Broberg, Brent A Lanting, Matthew G Teeter

{"title":"Phantom validation of a novel RSA-based impingement metric to assess component-on-component impingement risk.","authors":"Shahnaz Taleb, Jordan S Broberg, Brent A Lanting, Matthew G Teeter","doi":"10.1177/09544119241238950","DOIUrl":"10.1177/09544119241238950","url":null,"abstract":"Component-on-component impingement in total hip arthroplasty may lead to post-operative complications including dislocation. Despite numerous clinical studies focusing on reducing this risk, assessment methods remain limited to qualitative radiography, finite element analysis, and cadaver studies. There is a need for more precise measurements of impingement in the research setting. We aimed to validate a novel RSA-based impingement metric to measure component-on-component impingement in vivo. A phantom experiment of a standard metal-on-polyethylene total hip system was performed. RSA examinations were performed as typical for a traditional weight-bearing RSA exam for large joints. The phantom was placed in 10 possible impinged positions and one neutral position. Double exposure radiographs were taken to measure repeatability. The closest distance between the skirt of the head and the inner circumference of the acetabular cup liner was measured to assess impingement risk. Distances between the closest point of the hood to the edge of the cup in 10 impinged positions ranged from 0.05 to 1.03 mm, with the average being 0.67 mm. In the neutral position, the distance measured is 11.02 mm. Excellent repeatability was observed, with a standard deviation of 0.03 mm with an r value of 0.09. A validated RSA-based risk metric was established to evaluate in vivo hip impingement. A 1 mm threshold may be proposed to define impingement where distances approaching 1.00 mm are at a greater risk of impingement. This simplified metric holds promise for upcoming clinical studies on component-on-component impingement.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"483-487"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11083746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140194425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel design of hip-stem with reduced strain-shielding 减少应变屏蔽的新型髋关节茎干设计

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-04-22 DOI: 10.1177/09544119241244537

Tanmoy Loha, Rounak Bhattacharya, Bidyut Pal, Andrew A Amis

{"title":"A novel design of hip-stem with reduced strain-shielding","authors":"Tanmoy Loha, Rounak Bhattacharya, Bidyut Pal, Andrew A Amis","doi":"10.1177/09544119241244537","DOIUrl":"https://doi.org/10.1177/09544119241244537","url":null,"abstract":"The use of uncemented stems in hip arthroplasty has been increasing, even in osteoporotic patients. The major concerns of uncemented hip-stems, however, are peri-prosthetic fracture, thigh pain, and proximal femoral stress-/strain-shielding. In this study, a novel design of uncemented hip-stem is proposed that will reduce such concerns, improve osseointegration, and benefit both osteoporotic and arthritic patients. The stem has a central titanium alloy core surrounded by a set of radial buttresses that are partly porous titanium, as is the stem tip. The aim of the study was to investigate the mechanical behaviour of the proposed partly-porous design, examining load transfer in the short-term, and comparing its strain-shielding behaviour with a solid metal implant. The long-term effect of implant-induced bone remodelling was also simulated. Computed tomography based three-dimensional finite element models of an intact proximal femur, and the same femur implanted with the proposed design, were developed. Peak hip contact and major muscle forces corresponding to level-walking and stair climbing were applied. The proposed partly-porous design had approximately 50% lower strain-shielding than the solid-metal counterpart. Results of bone remodelling simulation indicated that only 16% of the total bone volume is subjected to reduction of bone density. Strain concentrations were observed in the bone around the stem-tip for both solid and porous implants; however, it was less prominent for the porous design. Lower strain-shielding and reduced bone resorption are advantageous for long-term fixation, and the reduced strain concentration around the stem-tip indicates a lower risk of peri-prosthetic fracture.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"58 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140805506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental investigation on punch shear strength of poly lactic acid specimens for biomedical applications 生物医学应用中聚乳酸试样冲剪强度的实验研究

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-04-17 DOI: 10.1177/09544119241245503

Shrutika Sharma, Vishal Gupta, Deepa Mudgal

{"title":"Experimental investigation on punch shear strength of poly lactic acid specimens for biomedical applications","authors":"Shrutika Sharma, Vishal Gupta, Deepa Mudgal","doi":"10.1177/09544119241245503","DOIUrl":"https://doi.org/10.1177/09544119241245503","url":null,"abstract":"The designed biomedical implants require excellent shear strength primarily for mechanical stability against forces in human body. However, metallic implants undergo stress shielding with release of toxic ions in the body. Thus, Fused Deposition Modeling (FDM) has made significant progress in the biomedical field through the production of customized implants. The mechanical behavior is highly dependent on printing parameters, however, the effect of these parameters on punch shear strength of ASTM D732-02 standard specimens has not been explored. Thus, in the current study, the effect of infill density (IFD), printing speed (PTS), wall thickness (WLT), and layer thickness (LYT) has been investigated on the punch shear strength using Response Surface Methodology. The Analysis of Variance (ANOVA) has been performed for predicting statistical model with 95% confidence interval. During the statistical analysis, the terms with p-value lower than 0.05 were considered significant and the influence of process parameters has been examined using microscopic images. The surface plots have been used for discussing the effect of interactions between printing parameters. The statistical results revealed IFD as the most significant contributing factor, followed by PTS, LYT, and WLT. The study concluded by optimization of printing parameters for obtaining the highest punch shear strength.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"20 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140614808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CONfidence: Developing an app to promote bladder and bowel health 信心：开发一款促进膀胱和肠道健康的应用程序

IF 1.8 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-04-17 DOI: 10.1177/09544119241246848

Nikki Cotterill, Knut Schroeder

{"title":"CONfidence: Developing an app to promote bladder and bowel health","authors":"Nikki Cotterill, Knut Schroeder","doi":"10.1177/09544119241246848","DOIUrl":"https://doi.org/10.1177/09544119241246848","url":null,"abstract":"The CONfidence app was developed to address an unmet need for access to self-help advice and information for bladder and bowel incontinence. The app was developed by the Bladder and Bowel CONfidence Health Integration Team and Expert Self Care and this paper describes the evolution of this innovation to empower patients and the public with bladder and bowel leakage. The app is intended to provide a proactive approach to continence promotion and not replace formal healthcare. Crucial steps were identified to ensuring this resource was accessible and understandable for the intended audience including: input from national clinical experts and individuals with lived experience to co-produce content, clear definition of scope, technical expertise in app development, clear language avoiding jargon or medical terms, credibility assurance and a strategic plan for dissemination. The app is free to download and will remain so to ensure evidence-based continence advice can be in the palm of all with a smartphone. The CONfidence app has been downloaded approaching 7000 times and is in use in 10 countries. A continual effort is required to share this resource as disclosure of these symptoms is shrouded in secrecy and many people could benefit from its content.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"20 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140617624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0