Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine最新文献

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A 3D-printed hybrid portable simulator for skills training in arthroscopic knee surgery. 一种用于关节镜膝关节手术技能训练的3d打印混合便携式模拟器。
IF 1.7 4区 医学
Carlos Javier Solis-Oviedo, Francisco Javier Pérez Jiménez, Jonathan Acuña Campos, César Iván Nájera Ríos, Miguel Ángel Bañuelos Saucedo, Fernando Pérez-Escamirosa
{"title":"A 3D-printed hybrid portable simulator for skills training in arthroscopic knee surgery.","authors":"Carlos Javier Solis-Oviedo, Francisco Javier Pérez Jiménez, Jonathan Acuña Campos, César Iván Nájera Ríos, Miguel Ángel Bañuelos Saucedo, Fernando Pérez-Escamirosa","doi":"10.1177/09544119251328414","DOIUrl":"https://doi.org/10.1177/09544119251328414","url":null,"abstract":"<p><p>Arthroscopic surgery has become the first option for the treatment of joint injuries. However, training outside the operating room is limited by the lack of portability and high cost of high-fidelity simulators. The aim of this study is to present the ArthSim hybrid simulator, a low-cost portable device for the training of psychomotor skills of orthopaedic surgeons in arthroscopic knee surgery. The ArthSim simulator consists of a physical model of the knee with an integrated motion tracking system with a virtual reality application that captures and replicates the movements of the knee joint and the two arthroscopic instruments inside the virtual model, in a mixed reality approach to arthroscopy training. The functionality of ArthSim's technology was evaluated in two experiments: static and dynamic. The interaction of the physical knee joint and the arthroscopic instruments within the virtual model was evaluated by eight orthopaedic surgeons, who recreated the common positions of the knee, arthroscope, and instruments during the exploration of the internal structures. The results indicated a surgical total workspace of 80 mm<sup>3</sup> with a range of motion of 115° for flexion, 23° for abduction, and 33° for rotation in the knee joint. The measurements showed linearity and repeatability with errors below, for motion capture. Feedback provided by orthopaedic surgeons on ArthSim was used to identify the device's points of improvement. The ArthSim simulator provides an effective alternative for arthroscopic training in a hybrid simulation approach, offering natural haptics to enhance the surgical experience of orthopaedic surgeons.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251328414"},"PeriodicalIF":1.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the mechanical properties and cell cultural behavior of diamond lattice scaffolds with different porosities. 不同孔隙率金刚石晶格支架的力学性能及细胞培养行为评价。
IF 1.7 4区 医学
Hojjat Ghahramanzadeh Asl, Selcen Çelik Uzuner, Salim Çam, Uğur Uzuner
{"title":"Evaluation of the mechanical properties and cell cultural behavior of diamond lattice scaffolds with different porosities.","authors":"Hojjat Ghahramanzadeh Asl, Selcen Çelik Uzuner, Salim Çam, Uğur Uzuner","doi":"10.1177/09544119251328434","DOIUrl":"https://doi.org/10.1177/09544119251328434","url":null,"abstract":"<p><p>Metal porous structures are a common treatment for bone tissue loss when the loss exceeds the self-repair capacity of the human body. The structural characteristics, mechanical properties, and biological behavior of scaffold biomaterials exert a significant influence on the formation of new bone cells. The objective of this study was to ascertain the mechanical and cell biological behavior of scaffold structures with four distinct porosities (60%, 70%, 80%, and 90%). Scaffold structures with a diamond lattice unit cell were manufactured by the selective laser melting method using a CoCr alloy powder with a diameter of 4 mm and a height of 5 mm and were then subjected to a static compression test. Subsequently, human gingival fibroblast cells were seeded into each sample via the cell culture process, and cell formation was observed. According to the results obtained from the compression test, the sample with 60% porosity demonstrated optimal mechanical performance and effective modulus of elasticity. In the cell culture process, the sample with 60% porosity exhibited the highest adherence rate.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251328434"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced prediction method of biological tissue mechanical response based on hybrid prediction model. 基于混合预测模型的生物组织机械响应高级预测方法。
IF 1.7 4区 医学
Jing Yang, Changwei Shi, Lihua Yao, Yixun Fang, Yiming Huang
{"title":"Advanced prediction method of biological tissue mechanical response based on hybrid prediction model.","authors":"Jing Yang, Changwei Shi, Lihua Yao, Yixun Fang, Yiming Huang","doi":"10.1177/09544119251327646","DOIUrl":"https://doi.org/10.1177/09544119251327646","url":null,"abstract":"<p><p>The mechanical response of biological tissue is an important basis for evaluating its state during the surgical operation. Accurate prediction of mechanical response is helpful to improve the precision of surgical operation. In this paper, An advanced prediction method based on hybrid prediction model is proposed and used to predict the mechanical response of soft tissue. Firstly, the simulation model of soft tissue indentation experiment was established to obtain the mechanical response under continuous loading condition. The mechanical response of kindy tissue under discontinuous loading was obtained by the actual indentation experiment. Secondly, the mechanical response is predicted and the influence of loading parameters on the prediction accuracy is analyzed. The mechanical response under continuous loading was obtained by simulation, and the mechanical response under non-continuous loading was obtained by indentation experiment. The proposed advanced prediction method is verified by the obtained mechanical responses. The results show that the proposed method can predict the mechanical response of soft tissue well. The proposed prediction algorithm is helpful to predict the mechanical response in advance and avoid the potential tissue damage caused by surgical operation.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251327646"},"PeriodicalIF":1.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of 3D printing in healthcare: A comprehensive review on treatment and training. 3D打印在医疗保健中的作用:对治疗和培训的全面回顾。
IF 1.7 4区 医学
Maruf Nizam, Rajesh Purohit, Mohammad Taufik
{"title":"Role of 3D printing in healthcare: A comprehensive review on treatment and training.","authors":"Maruf Nizam, Rajesh Purohit, Mohammad Taufik","doi":"10.1177/09544119251321585","DOIUrl":"https://doi.org/10.1177/09544119251321585","url":null,"abstract":"<p><p>Additive manufacturing (AM) is revolutionizing healthcare by enabling the creation of customized 3D printed (3DP) medical equipment, implants, orthoses, prosthetics, drugs, and organs. With the availability of different types of materials suitable for 3DP and healthcare applications, this technology allows for the precise fabrication of patient-oriented prosthetics, dental implants, and orthopedic devices, significantly improving fit and functionality. Additionally, 3DP drugs, such as Oral Dispersible Formulations (ODFs) and polypills, are surpassing the traditional \"one pill fits all\" concept, offering more tailored medication solutions. This innovation also supports the development of personalized medications and bioprinted tissues, opening the way for advancements in regenerative medications and tailored therapies. 3D-bioprinted organs are addressing the growing demand for organ transplants. In surgical planning, 3D-printed anatomical models provide students and professionals with hands-on practice, which is crucial for skill development and understanding complex anatomies. Surgeons can also practice and refine techniques before actual procedures, enhancing precision and improving outcomes during real operations. This paper focus on highlighting the progression and motivations behind the cross-disciplinary applications of AM within the healthcare sector providing customized medical devices, drug delivery systems and diagnostic tools for personalized treatment and skill refinement. This paper is designed for a broad audience, including manufacturing professionals and researchers, who are interested in exploring the medical implications of this transformative technology.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251321585"},"PeriodicalIF":1.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technological interventions for the suppression of hand tremors: A literature review. 抑制手颤的技术干预:文献综述。
IF 1.7 4区 医学
Krishnakumar Sankar, Mohammed Aasim Subairdeen, Navaneetha Krishnan Muthukrishnan
{"title":"Technological interventions for the suppression of hand tremors: A literature review.","authors":"Krishnakumar Sankar, Mohammed Aasim Subairdeen, Navaneetha Krishnan Muthukrishnan","doi":"10.1177/09544119251325115","DOIUrl":"https://doi.org/10.1177/09544119251325115","url":null,"abstract":"<p><p>A tremor is a neurological disorder that results in trembling or shaking in one or more body parts. A thorough literature review was conducted to investigate the methods for suppressing tremors. We looked for articles published between 1995 and 2024 in the databases CINAHL (Cumulative Index to Nursing and Allied Health Literature), PubMed, Medline, Embase, Scopus, and Cochrane. Two thousand two hundred fifty distinct items were discovered after an extensive search. Based only on the title, 250 were included. Two hundred papers were deemed ineligible after the abstracts were assessed. The remaining 26 articles were shortlisted after screening titles and abstracts and categorized based on treatment methods for hand tremors. According to the study's findings, deep brain stimulation (DBS) and electrical stimulation both reduced tremors considerably. It was also evident that attenuation systems and passive devices lessen the effects of tremors; target tracking tasks can lessen physiological tremors in postural posture; ET may have better hand functions after cold water treatment than warm water or at baseline; and targeted ultrasound thalamotomy is an effective treatment for ET, as it improved quality of life (QoL) significantly. Additionally, the design, development, and evaluation of wearable devices and pharmaceutical interventions for tremor suppression were investigated in detail. The main objective was to perform a comparative analysis of the merits and demerits of both treatment methodologies in terms of functional outcomes, users' comfort, and side effects. The review highlights wearable devices as a beneficial option for tremor suppression, offering comfort, safety, and advanced technology over pharmaceutical intervention methodologies.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251325115"},"PeriodicalIF":1.7,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning and robotics enabled approach for audio based emotional pragmatics deficits identification in social communication disorders. 基于深度学习和机器人技术的音频情感语用缺陷识别方法。
IF 1.7 4区 医学
Muskan Chawla, Surya Narayan Panda, Vikas Khullar
{"title":"Deep learning and robotics enabled approach for audio based emotional pragmatics deficits identification in social communication disorders.","authors":"Muskan Chawla, Surya Narayan Panda, Vikas Khullar","doi":"10.1177/09544119251325331","DOIUrl":"https://doi.org/10.1177/09544119251325331","url":null,"abstract":"<p><p>The aim of this study is to develop Deep Learning (DL) enabled robotic systems to identify audio-based emotional pragmatics deficits in individuals with social pragmatic communication deficits. The novelty of the work stems from its integration of deep learning with a robotics platform for identifying emotional pragmatics deficits. In this study, the proposed methodology utilizes the implementation of machine and DL-based classification techniques, which have been applied to a collection of open-source datasets to identify audio emotions. The application of pre-processing and converting audio signals of different emotions utilizing Mel-Frequency Cepstral Coefficients (MFCC) resulted in improved emotion classification. The data generated using MFCC were used for the training of machine or DL models. The trained models were then tested on a randomly selected dataset. DL has been proven to be more effective in the identification of emotions using robotic structure. As the data generated by MFCC is of a single dimension, therefore, one-dimensional DL algorithms, such as 1D-Convolution Neural Network, Long Short-Term Memory, and Bidirectional-Long Short-Term Memory, were utilized. In comparison to other algorithms, bidirectional Long Short-Term Memory model has resulted in higher accuracy (96.24%), loss (0.2524 in value), precision (92.87%), and recall (92.87%) in comparison to other machine and DL algorithms. Further, the proposed model was deployed on the robotic structure for real-time detection for improvement of social-emotional pragmatic responses in individuals with deficits. The approach can serve as a potential tool for the individuals with pragmatic communication deficits.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251325331"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel preoperative prosthetic position planning algorithm for total hip arthroplasty based on the no-impingement principle: A case study. 一种基于无碰撞原则的全髋关节置换术术前假体位置规划算法:一个案例研究。
IF 1.7 4区 医学
Tao Feng, Hao Tang, Xiaogang Zhang, Yali Zhang, Yixin Zhou, Zhongmin Jin
{"title":"A novel preoperative prosthetic position planning algorithm for total hip arthroplasty based on the no-impingement principle: A case study.","authors":"Tao Feng, Hao Tang, Xiaogang Zhang, Yali Zhang, Yixin Zhou, Zhongmin Jin","doi":"10.1177/09544119251319960","DOIUrl":"https://doi.org/10.1177/09544119251319960","url":null,"abstract":"<p><p>Most preoperative planning calculations of impingement-free range of motion (IFROM) and impingement-free safe zone (IFSZ) rarely consider non-standard shaped prostheses and bony impingement (BI) for total hip arthroplasty (THA). This research developed a novel algorithm that considers BI, prosthetic impingement, pelvic tilt angle (<i>PT</i>) in the sagittal plane, and non-standard-shaped hip prostheses. This research aimed to investigate the effect of BI and <i>PT</i> on hip IFROM, IFSZ, and the BI rate. Using this algorithm to calculate a case, we found that when considering BI, (1) the upper limit of the hip IFROM was decreased, and the different <i>PT</i> affected the upper limit of the hip IFROM of various movements; (2) the BI rate of the flat-rim liner in standing and sitting postures were 54.6% and 67%; and (3) the maximum IFSZ size of the flat-rim liner was reduced by 12%, the reduction rate of the combined pelvic position with a non-zero IFSZ size was 83.2% for the flat-rim liner. Consideration of BI further reduces the IFROM, the IFSZ size, and the number of the combined position of the pelvis with a non-zero IFSZ size of the hip joint. Importantly, this algorithm provides a reliable tool for personalized prosthesis positioning for THA. This algorithm has excellent applications in personalized surgical planning and surgical robotics.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251319960"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthetic data generation in motion analysis: A generative deep learning framework. 运动分析中的合成数据生成:生成式深度学习框架。
IF 1.7 4区 医学
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-02-01 Epub Date: 2025-02-04 DOI: 10.1177/09544119251315877
Mattia Perrone, Steven P Mell, John T Martin, Shane J Nho, Scott Simmons, Philip Malloy
{"title":"Synthetic data generation in motion analysis: A generative deep learning framework.","authors":"Mattia Perrone, Steven P Mell, John T Martin, Shane J Nho, Scott Simmons, Philip Malloy","doi":"10.1177/09544119251315877","DOIUrl":"10.1177/09544119251315877","url":null,"abstract":"<p><p>Generative deep learning has emerged as a promising data augmentation technique in recent years. This approach becomes particularly valuable in areas such as motion analysis, where it is challenging to collect substantial amounts of data. The objective of the current study is to introduce a data augmentation strategy that relies on a variational autoencoder to generate synthetic data of kinetic and kinematic variables. The kinematic and kinetic variables consist of hip and knee joint angles and moments, respectively, in both sagittal and frontal plane, and ground reaction forces. Statistical parametric mapping (SPM) did not detect significant differences between real and synthetic data for each of the biomechanical variables considered. To further evaluate the effectiveness of this approach, a long-short term model (LSTM) was trained both only on real data (R) and on the combination of real and synthetic data (R&S); the performance of each of these two trained models was then assessed on real test data unseen during training. The principal findings included achieving comparable results in terms of nRMSE when predicting knee joint moments in the frontal (R&S: 9.86% vs R: 10.72%) and sagittal plane (R&S: 9.21% vs R: 9.75%), and hip joint moments in the frontal (R&S: 16.93% vs R: 16.79%) and sagittal plane (R&S: 13.29% vs R: 14.60%). The main novelty of this study lies in introducing an effective data augmentation approach in motion analysis settings.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"202-211"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Data Lake: A storage platform for bone texture analysis. 骨数据湖:骨结构分析的存储平台。
IF 1.7 4区 医学
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-02-01 Epub Date: 2025-02-20 DOI: 10.1177/09544119251318434
Marcin Wolski, Tomasz Woloszynski, Gwidon Stachowiak, Pawel Podsiadlo
{"title":"Bone Data Lake: A storage platform for bone texture analysis.","authors":"Marcin Wolski, Tomasz Woloszynski, Gwidon Stachowiak, Pawel Podsiadlo","doi":"10.1177/09544119251318434","DOIUrl":"10.1177/09544119251318434","url":null,"abstract":"<p><p>Trabecular bone (TB) texture regions selected on hand and knee X-ray images can be used to detect and predict osteoarthritis (OA). However, the analysis has been impeded by increasing data volume and diversification of data formats. To address this problem, a novel storage platform, called Bone Data Lake (BDL) is proposed for the collection and retention of large numbers of images, TB texture regions and parameters, regardless of their structure, size and source. BDL consists of three components, i.e.: a raw data storage, a processed data storage, and a data reference system. The performance of the BDL was evaluated using 20,000 knee and hand X-ray images of various formats (DICOM, PNG, JPEG, BMP, and compressed TIFF) and sizes (from 0.3 to 66.7 MB). The images were uploaded into BDL and automatically converted into a standardized 8-bit grayscale uncompressed TIFF format. TB regions of interest were then selected on the standardized images, and a data catalog containing metadata information about the regions was constructed. Next, TB texture parameters were calculated for the regions using Variance Orientation Transform (VOT) and Augmented VOT (AVOT) methods and stored in XLSX files. The files were uploaded into BDL, and then transformed into CSV files and cataloged. Results showed that the BDL efficiently transforms images and catalogs bone regions and texture parameters. BDL can serve as the foundation of a reliable, secure and collaborative system for OA detection and prediction based on radiographs and TB texture.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"190-201"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of mechanical biocompatibility of cog threads for prolapse repair. 脱垂修复用齿轮螺纹的机械生物相容性评价。
IF 1.7 4区 医学
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-02-01 Epub Date: 2025-04-02 DOI: 10.1177/09544119251321130
N M Ferreira, M E T Silva, M P L Parente, F Pinheiro, T Mascarenhas, A A Fernandes
{"title":"Evaluation of mechanical biocompatibility of cog threads for prolapse repair.","authors":"N M Ferreira, M E T Silva, M P L Parente, F Pinheiro, T Mascarenhas, A A Fernandes","doi":"10.1177/09544119251321130","DOIUrl":"https://doi.org/10.1177/09544119251321130","url":null,"abstract":"<p><p>Pelvic floor disorders (PFD), including Pelvic Organ Prolapse (POP), can negatively impact a woman's daily activities and quality of life. POP is a growing concern, with an increasing number of cases each year and significant numbers of women going through surgery to alleviate it. Traditional interventions like the use of mesh implants have certain limitations such as repeated surgeries. An alternative surgical intervention technique using injectable biodegradable cog threads was suggested. The application of Finite element analysis (FEA) to this research allows us to personalize and select suitable POP correction techniques and study the effect of alternative reinforcement techniques. The 3D computational model of the vagina will be used to simulate defect repair using cog threads. To accurately model this, we conducted uniaxial tensile tests on both the polycaprolactone (PCL) cog threads and the sow's vaginal tissues, which mimic human tissue, providing vital data for precise finite element modeling. The study's findings suggest that cog threads may have the potential to provide benefits in the treatment of POP. This study provides a starting point for further research on cog threads as one possible treatment option for POP.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"239 2","pages":"155-164"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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