Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine最新文献

Effects of self-expandable pedicle screws with shape memory alloy structures on spinal fixation strength: A finite element study. 具有形状记忆合金结构的自膨胀椎弓根螺钉对脊柱固定强度的影响：有限元研究

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-23 DOI: 10.1177/09544119241298535

Mahdi Mohammad Asghari, Aisa Rassoli, Hedayeh Mehmanparast

{"title":"Effects of self-expandable pedicle screws with shape memory alloy structures on spinal fixation strength: A finite element study.","authors":"Mahdi Mohammad Asghari, Aisa Rassoli, Hedayeh Mehmanparast","doi":"10.1177/09544119241298535","DOIUrl":"https://doi.org/10.1177/09544119241298535","url":null,"abstract":"In many spine surgeries, pedicle screws are commonly used to stabilize vertebrae, however, loosening can be a complication. Different designs have shown improvements in fixation strength, with self-expandable screws featuring shape memory alloy (SMA) structures being of particular interest. This study aimed to assess the fixation strength of self-expandable pedicle screws made with SMA (specifically Nickel-Titanium) sheets. Three types of screws were evaluated: self-expandable screws with a smooth SMA surface, self-expandable screws with a porous SMA surface, and standard design screws. Each screw underwent pullout tests for comparison. Following the tests, the self-expandable screw with a porous surface exhibited the highest pullout force (1141.83 N), compared to 1056.86 N for the smooth self-expandable screw and 1104.25 N for the standard screw. The dissipated plastic strain energy differed among the screws, with values of 0.073 J for the porous self-expandable screw, 0.065 J for the smooth self-expandable screw, and 0.089 J for the standard pedicle screw. Notably, the porous self-expandable screw showed reduced stress on the bone-screw interface. Improving the mechanical design of pedicle screws could significantly enhance screw-bone fixation strength. The utilization of self-expandable pedicle screws with porous surface SMA sheets demonstrates superior performance, potentially mitigating complications like loosening.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241298535"},"PeriodicalIF":1.7,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortical bone fracture analysis including the combined influence of osteon orientations, applied load and crack lengths: A numerical investigation. 皮质骨断裂分析（包括骨质取向、外加载荷和裂缝长度的综合影响）：数值研究。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-22 DOI: 10.1177/09544119241299081

Ajay Kumar, Himanshu Pathak, Rajesh Ghosh

{"title":"Cortical bone fracture analysis including the combined influence of osteon orientations, applied load and crack lengths: A numerical investigation.","authors":"Ajay Kumar, Himanshu Pathak, Rajesh Ghosh","doi":"10.1177/09544119241299081","DOIUrl":"https://doi.org/10.1177/09544119241299081","url":null,"abstract":"Similar to how fiber orientation affects composite materials, osteon orientation affects the elasticity and fracture behavior of cortical bone. The objective of this work is to predict the combined effect of orientations of the osteon, applied load, and various crack lengths on the fracture characteristics of cortical bone. Orthotropic modeling and analyses of cortical bone were carried out using the linear-elastic fracture mechanics (LEFM) based extended finite element method (XFEM). Five values of applied mode-I and mode-II load, five distinct crack lengths, and seven angular osteon orientations were taken into consideration to predict the change in SIF. In this work, the 2-D plane stress assumption with a straight-edge crack was taken into consideration. It was found that the values of SIF significantly increased when the load (15-35 MPa) and fracture length (1.8-2.2 mm) increased. SIF (KI) values under mode-I loading were discovered to be substantially lower than SIF (KI and KII) values under mode-II loading. Results of this study showed that osteon orientations with different crack lengths and applied loads had a significant impact on cortical bone fracture characteristics. Only the crack's opening was discovered to be caused by mode-I loading; however, both the opening and shearing of the crack were found to be caused by mode-II loading. Despite differences in applied loads, crack lengths, and osteon orientations, the values of the SIF predicted in this work (under mode-I loading) using LEFM-based XFEM exhibited good agreement with the prior published experimental and numerical data.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241299081"},"PeriodicalIF":1.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review of energy storing dynamic response foot for prosthetic rehabilitation. 对用于假肢康复的蓄能动态响应脚进行系统回顾。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-22 DOI: 10.1177/09544119241295342

Swapna Sahoo, Rajesh Kumar Mohanty, Aswini Kumar Mohapatra

{"title":"A systematic review of energy storing dynamic response foot for prosthetic rehabilitation.","authors":"Swapna Sahoo, Rajesh Kumar Mohanty, Aswini Kumar Mohapatra","doi":"10.1177/09544119241295342","DOIUrl":"https://doi.org/10.1177/09544119241295342","url":null,"abstract":"The purpose of this paper is to undertake a systematic review on various mechanical design considerations, simulation and optimization techniques as well as the clinical applications of energy storing and return (ESAR) prosthetic feet used in amputee rehabilitation. Methodological databases including PubMed, EMBASE, and SCOPUS were searched till July 2022, and the retrieved records were evaluated for relevance. The design, mechanism, materials used, mechanical and simulation techniques and clinical applications of ESAR foot used in developed and developing nations were reviewed. 61 articles met the inclusion criteria out of total 577 studies. A wide variety of design matrices for energy- storing feet was found, but the clinical relevance of its design parameters is uncommon. Definitive factors on technical and clinical characteristics were derived and included in the summary tables. To modify existing foot failure mechanisms, material selection and multiple experiments must be improved. Gait analysis and International Organization for Standardization (ISO) mechanical testing standards of energy-storing feet were the methods for integrating clinical experimentation with numerical results. To meet technological requirements, various frameworks simulate finite element models of the energy-storing foot, whereas clinical investigations involving gait analysis require proper insight. Analysis of structural behavior under varying loads and its effect on studies of functional gait are limited. For optimal functional performance, durability and affordability, more research and technological advancements are required to characterize materials and standardize prosthetic foot protocols.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241295342"},"PeriodicalIF":1.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization and control of robotic vertebral plate grinding: Predictive modeling, parameter optimization, and fuzzy control strategies for minimizing bone damage in laminectomy procedures. 机器人椎板打磨的优化与控制：预测建模、参数优化和模糊控制策略，最大限度减少椎板切除术中的骨损伤。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-19 DOI: 10.1177/09544119241292192

Heqiang Tian, Jinchang An, Hongqiang Ma, Bo Pang, Junqiang Liu

{"title":"Optimization and control of robotic vertebral plate grinding: Predictive modeling, parameter optimization, and fuzzy control strategies for minimizing bone damage in laminectomy procedures.","authors":"Heqiang Tian, Jinchang An, Hongqiang Ma, Bo Pang, Junqiang Liu","doi":"10.1177/09544119241292192","DOIUrl":"https://doi.org/10.1177/09544119241292192","url":null,"abstract":"During the robotic grinding of vertebral plates in high-risk laminectomy procedures, programmed operations may inadvertently induce force or temperature-related damage to the bone tissue. Therefore, it is imperative to explore a control methodology aimed at minimizing such damage during the robotic grinding of vertebral plate cortical bone, contingent upon optimal grinding parameters. Initially, predictive models for both the grinding force and temperature of vertebral plate cortical bone were developed using the response surface design (RSD) methodology. Subsequently, employing the satisfaction function approach, multi-objective parameter optimization of these predictive models was conducted to ascertain the optimal combination of parameters conducive to low-damage grinding. The optimum grinding parameters identified were a speed of 6000 r/min, a depth of grind of 0.4 mm, and a feed rate of 3.8 mm/s. Moreover, a multi-layer adaptive fuzzy control strategy was devised, and a corresponding multi-layer adaptive fuzzy controller (MFLC) was then implemented to dynamically adjust the grinding feed speed. The efficacy of this control module was corroborated through Simulink simulations. Simulation results demonstrated that the magnitude of the grinding force fluctuated within the range of 2.2-2.6 N after FLC control, while the fluctuation range of the grinding force was limited to 2.2-2.48 N after MFLC control. This indicates that MFLC control brings the force closer to the target expectation value of 2.39 N compared with FLC control. Finally, the dynamic fuzzy control method predicated on optimal grinding parameters was validated through experimental porcine spine grinding conducted on a robotic vertebral plate grinding platform.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241292192"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A wavelet and local binary pattern-based feature descriptor for the detection of chronic infection through thoracic X-ray images. 基于小波和局部二进制模式的特征描述器，用于通过胸部 X 光图像检测慢性感染。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-19 DOI: 10.1177/09544119241293007

Amar Kumar Verma, Prerna Saurabh, Deep Madhukant Shah, Vamsi Inturi, Radhika Sudha, Sabareesh Geetha Rajasekharan, Rajkumar Soundrapandiyan

{"title":"A wavelet and local binary pattern-based feature descriptor for the detection of chronic infection through thoracic X-ray images.","authors":"Amar Kumar Verma, Prerna Saurabh, Deep Madhukant Shah, Vamsi Inturi, Radhika Sudha, Sabareesh Geetha Rajasekharan, Rajkumar Soundrapandiyan","doi":"10.1177/09544119241293007","DOIUrl":"10.1177/09544119241293007","url":null,"abstract":"This investigation attempts to propose a novel Wavelet and Local Binary Pattern-based Xception feature Descriptor (WLBPXD) framework, which uses a deep-learning model for classifying chronic infection amongst other infections. Chronic infection (COVID-19 in this study) is identified via RT-PCR test, which is time-consuming and requires a dedicated laboratory (materials, equipment, etc.) to complete the clinical results. X-rays and computed tomography images from chest scans offer an alternative method for identifying chronic infections. It has been demonstrated that chronic infection can be diagnosed from X-ray images acquired in a real-world setting. The images are transformed using the discrete wavelet transform (DWT), combined with the local binary pattern (LBP) technique. Pre-trained deep-learning models, such as AlexNet, Xception, VGG-16 and Inception Resnet50, extract the features. Subsequently, the extracted features are fused using feature-fusion approaches and subjected to classification. The AlexNet, in conjunction with the DWT model, produced 99.7% accurate results, whereas the AlexNet and the LBP model produced 99.6% accurate results. Therefore, the proposed method is efficient as it offers a better detection accuracy and eventually enhances the scope of early detection, thus assisting the clinical perspectives.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241293007"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

User experience of lower extremity exoskeletons and its improvement methodologies: A narrative review. 下肢外骨骼的用户体验及其改进方法：叙述性综述。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-17 DOI: 10.1177/09544119241291194

Yuan Zhou

{"title":"User experience of lower extremity exoskeletons and its improvement methodologies: A narrative review.","authors":"Yuan Zhou","doi":"10.1177/09544119241291194","DOIUrl":"https://doi.org/10.1177/09544119241291194","url":null,"abstract":"In this review, user experience (UX) of recent lower limb exoskeletons (LLEs) and its improvement methodologies are investigated. First, statistics based on standardised and custom UX evaluations are presented. It is indicated that, LLE users have positive UX, especially in the aspects of safety, dimension and effectiveness. Further, overall, UX levels of ankle and hip-knee exoskeletons are higher than those of other exoskeleton types; unilateral LLEs have higher mean UX levels than that of the bilateral ones. Then, design practices for improving UX are studied; the focused points are burden reduction and improvement of device fit. The former is achieved through lightweight design and approaches that reduce device's moment of inertia (MOI) at mechanical joints. Works on the latter refer to the endeavours to enhance static and dynamic fit; they mainly rely on the optimisations of human-robot interface (HRS) and endeavours to rectify misalignment of axes of mechanical and anatomic joints, respectively. The following section is control approaches to enhance wearing comfort level; it is mainly focused on adaptive, interaction and compensation-based controls. Finally, existing problems and future directions are stated and prospected respectively.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241291194"},"PeriodicalIF":1.7,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving arterial stiffness prediction with machine learning utilizing hemodynamics and biomechanical features derived from phase contrast magnetic resonance imaging. 利用相位对比磁共振成像得出的血液动力学和生物力学特征，通过机器学习改进动脉僵化预测。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-12 DOI: 10.1177/09544119241291191

Asma Ayadi, Imen Hammami, Wassila Sahtout, Olivier Baledant

{"title":"Improving arterial stiffness prediction with machine learning utilizing hemodynamics and biomechanical features derived from phase contrast magnetic resonance imaging.","authors":"Asma Ayadi, Imen Hammami, Wassila Sahtout, Olivier Baledant","doi":"10.1177/09544119241291191","DOIUrl":"https://doi.org/10.1177/09544119241291191","url":null,"abstract":"Arterial stiffness has emerged as a prominent marker of risk for cardiovascular diseases. Few studies are interested in predicting symptomatic or asymptomatic arterial stiffness from hemodynamics and biomechanics parameters. Machine learning models can be used as an intelligent tool for arterial stiffness detection based on hemodynamic and biomechanical parameters. Indeed, in the case of arterial stiffness hemodynamics and biomechanics parameters present significant change, such as an increase in age, local wave velocity, arterial elastance, Young's modulus, reflected wave amplitude, decrease in arterial compliance, reflected wave arrival time, and reflection coefficient. This study aims to assess the impact of artificial intelligence using machine-learning algorithms for the detection of arterial stiffness. The ability of various machine-learning approaches can be investigated to predict wall stiffness in the carotid artery and to evaluate the risk of cardiovascular events. A mathematical model developed in previous work was used to determine hemodynamic and biomechanical parameters. Accuracy, sensitivity, and specificity are calculated to evaluate the performance of the proposed models. All used classifiers demonstrated high performance in predicting arterial stiffness, notably with the Support Vector Machine, Artificial Neural Network, and Decision Tree classifiers achieving exceptional accuracies of 100%. In this study, the potential of machine learning based on hemodynamic parameters for the prediction of symptomatic and asymptomatic arterial stiffness was demonstrated.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241291191"},"PeriodicalIF":1.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis methods of Mg-based scaffolds and their applications in tissue engineering: A review. 镁基支架的合成方法及其在组织工程中的应用：综述。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-11-11 DOI: 10.1177/09544119241289504

Hurieh Mohammadzadeh, Robabeh Jafari, Behnam Doudkanlouy Milan, Mohammad Jangju

{"title":"Synthesis methods of Mg-based scaffolds and their applications in tissue engineering: A review.","authors":"Hurieh Mohammadzadeh, Robabeh Jafari, Behnam Doudkanlouy Milan, Mohammad Jangju","doi":"10.1177/09544119241289504","DOIUrl":"https://doi.org/10.1177/09544119241289504","url":null,"abstract":"Repair and regeneration of damaged tissues due to disease and accidents have become a severe challenge to tissue engineers and researchers. In recent years, biocompatible metal materials such as stainless steels, cobalt alloys, titanium alloys, tantalum alloys, nitinol, and Mg alloys have been studied for tissue engineering applications; as suitable candidates in orthopedic and dentistry implants. These materials and their alloys are used for load-bearing and physiological roles in biological applications. Due to the suitable conditions provided by a porous material, many studies have been performed on the porous implants, including Mg-based scaffolds. Mg alloy scaffolds are attractive due to some outstanding features and susceptibilities, such as providing a cell matrix for cell proliferation, migration, and regeneration, providing metabolic substances for bone tissue growth, biocompatibility, good biodegradability, elastic modulus comparable to the natural bone, etc. Accordingly, in the present study, a general classification of all the production methods of Mg-based scaffolds is provided. Strengths and weaknesses, the effect of the production approach on the final properties of scaffolds, including mechanical and biological capabilities, and the impact of alloying elements and process parameters have been reviewed, and discussed. Finally, the manufacturing methods have been compared and the upcoming challenges have been stated.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241289504"},"PeriodicalIF":1.7,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial performance of nanosecond laser irradiated zirconium-based bulk metallic glass. 纳秒激光辐照锆基块状金属玻璃的抗菌性能。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-10-01 Epub Date: 2024-10-08 DOI: 10.1177/09544119241285659

Cezhi Du, Chengyong Wang, Jianbo Sui, Lijuan Zheng

{"title":"Antibacterial performance of nanosecond laser irradiated zirconium-based bulk metallic glass.","authors":"Cezhi Du, Chengyong Wang, Jianbo Sui, Lijuan Zheng","doi":"10.1177/09544119241285659","DOIUrl":"10.1177/09544119241285659","url":null,"abstract":"Bulk metallic glasses (BMGs) have garnered significant attention in recent decades due to the outstanding physical, chemical, and biomedical characteristics. The biomedical application of metallic glass also received extensive attention. This report investigates the interplay among antibacterial performance, crystallization and processing parameters of Zr-based bulk metallic glass (Zr-BMG) following nanosecond laser irradiation. We examined surface morphology, crystallization behavior, surface quality, binding energy, and ion release properties post-laser irradiation. Additionally, we evaluated the generation of reactive oxygen species upon immersion of Zr-BMG in phosphate-buffered saline using the 2',7'-dichlorofluorescin diacetate method. Staphylococcus aureus was chosen to assess Zr-BMG's antibacterial performance, while mouse osteoblasts were utilized to investigate in vitro cytotoxicity. Our findings revealed that at laser energy intensities below 0.08 J/mm2, the amorphous structure of Zr-BMG remained intact after irradiation. Moreover, laser irradiation significantly enhanced the antibacterial performance of Zr-BMG. The release rate of ion, concentration of reactive oxygen species, and antibacterial properties exhibited direct proportionality to laser energy intensity. However, surfaces exhibiting high antibacterial efficacy also displayed elevated cytotoxicity. The surface irradiated with a 7 μJ ablation pulse and 200 mm/s irradiation speed demonstrated a superior balance between antibacterial and cytotoxic properties while maintaining an amorphous state. We hope this research can provide theoretical reference and data support for the application of metallic glass in biomedical application.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"973-984"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of bone ingrowth into a porous novel hip-stem: A finite element analysis integrated with mechanoregulatory algorithm. 多孔新型髋关节干的骨生长预测：结合机械调节算法的有限元分析。

IF 1.7 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2024-10-01 Epub Date: 2024-10-14 DOI: 10.1177/09544119241286958

Tanmoy Loha, Kaushik Mukherjee, Bidyut Pal

{"title":"Prediction of bone ingrowth into a porous novel hip-stem: A finite element analysis integrated with mechanoregulatory algorithm.","authors":"Tanmoy Loha, Kaushik Mukherjee, Bidyut Pal","doi":"10.1177/09544119241286958","DOIUrl":"10.1177/09544119241286958","url":null,"abstract":"Bone ingrowth into a porous implant is necessary for its long-term fixation. Although attempts have been made to quantify the peri-implant bone growth using finite element (FE) analysis integrated with mechanoregulatory algorithms, bone ingrowth into a porous cellular hip stem has scarcely been investigated. Using a three-dimensional (3D) FE model and mechanobiology-based numerical framework, the objective of this study was to predict the spatial distribution of evolutionary bone ingrowth into an uncemented novel porous hip stem proposed earlier by the authors. A CT-based FE macromodel of the implant-bone structure was developed. The bone material properties were assigned based on CT grey value. Peak musculoskeletal loading conditions, corresponding to level walking and stair climbing, were applied. The geometry of the implant-bone macromodel was divided into multiple submodels. A suitable mapping framework was used to transfer maximum nodal displacements from the FE macromodel to the cut boundaries of the FE submodels. CT grey value-based bone materials properties were assigned to the submodels. Thereafter, the submodels were solved and simulations of bone ingrowth were carried out using mechanoregulatory principle. A gradual increase in the average Young's modulus, from 1200 to 1500 MPa, of the bone tissue layer was observed considering all the submodels. The distal submodel exhibited 82% of bone ingrowth, whereas the proximal submodel experienced 65% bone ingrowth. Equilibrium in the bone ingrowth process was achieved in 7 weeks postoperatively, with a notable amount of bone ingrowth that should lead to biological fixation of the novel hip stem.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"992-1004"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0