Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine最新文献

{"title":"Evaluation of the mechanical properties and cell cultural behavior of diamond lattice scaffolds with different porosities.","authors":"Hojjat Ghahramanzadeh Asl, Selcen Çelik Uzuner, Salim Çam, Uğur Uzuner","doi":"10.1177/09544119251328434","DOIUrl":"https://doi.org/10.1177/09544119251328434","url":null,"abstract":"<p><p>Metal porous structures are a common treatment for bone tissue loss when the loss exceeds the self-repair capacity of the human body. The structural characteristics, mechanical properties, and biological behavior of scaffold biomaterials exert a significant influence on the formation of new bone cells. The objective of this study was to ascertain the mechanical and cell biological behavior of scaffold structures with four distinct porosities (60%, 70%, 80%, and 90%). Scaffold structures with a diamond lattice unit cell were manufactured by the selective laser melting method using a CoCr alloy powder with a diameter of 4 mm and a height of 5 mm and were then subjected to a static compression test. Subsequently, human gingival fibroblast cells were seeded into each sample via the cell culture process, and cell formation was observed. According to the results obtained from the compression test, the sample with 60% porosity demonstrated optimal mechanical performance and effective modulus of elasticity. In the cell culture process, the sample with 60% porosity exhibited the highest adherence rate.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251328434"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced prediction method of biological tissue mechanical response based on hybrid prediction model.","authors":"Jing Yang, Changwei Shi, Lihua Yao, Yixun Fang, Yiming Huang","doi":"10.1177/09544119251327646","DOIUrl":"https://doi.org/10.1177/09544119251327646","url":null,"abstract":"<p><p>The mechanical response of biological tissue is an important basis for evaluating its state during the surgical operation. Accurate prediction of mechanical response is helpful to improve the precision of surgical operation. In this paper, An advanced prediction method based on hybrid prediction model is proposed and used to predict the mechanical response of soft tissue. Firstly, the simulation model of soft tissue indentation experiment was established to obtain the mechanical response under continuous loading condition. The mechanical response of kindy tissue under discontinuous loading was obtained by the actual indentation experiment. Secondly, the mechanical response is predicted and the influence of loading parameters on the prediction accuracy is analyzed. The mechanical response under continuous loading was obtained by simulation, and the mechanical response under non-continuous loading was obtained by indentation experiment. The proposed advanced prediction method is verified by the obtained mechanical responses. The results show that the proposed method can predict the mechanical response of soft tissue well. The proposed prediction algorithm is helpful to predict the mechanical response in advance and avoid the potential tissue damage caused by surgical operation.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251327646"},"PeriodicalIF":1.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of 3D printing in healthcare: A comprehensive review on treatment and training.","authors":"Maruf Nizam, Rajesh Purohit, Mohammad Taufik","doi":"10.1177/09544119251321585","DOIUrl":"https://doi.org/10.1177/09544119251321585","url":null,"abstract":"<p><p>Additive manufacturing (AM) is revolutionizing healthcare by enabling the creation of customized 3D printed (3DP) medical equipment, implants, orthoses, prosthetics, drugs, and organs. With the availability of different types of materials suitable for 3DP and healthcare applications, this technology allows for the precise fabrication of patient-oriented prosthetics, dental implants, and orthopedic devices, significantly improving fit and functionality. Additionally, 3DP drugs, such as Oral Dispersible Formulations (ODFs) and polypills, are surpassing the traditional \"one pill fits all\" concept, offering more tailored medication solutions. This innovation also supports the development of personalized medications and bioprinted tissues, opening the way for advancements in regenerative medications and tailored therapies. 3D-bioprinted organs are addressing the growing demand for organ transplants. In surgical planning, 3D-printed anatomical models provide students and professionals with hands-on practice, which is crucial for skill development and understanding complex anatomies. Surgeons can also practice and refine techniques before actual procedures, enhancing precision and improving outcomes during real operations. This paper focus on highlighting the progression and motivations behind the cross-disciplinary applications of AM within the healthcare sector providing customized medical devices, drug delivery systems and diagnostic tools for personalized treatment and skill refinement. This paper is designed for a broad audience, including manufacturing professionals and researchers, who are interested in exploring the medical implications of this transformative technology.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251321585"},"PeriodicalIF":1.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technological interventions for the suppression of hand tremors: A literature review.","authors":"Krishnakumar Sankar, Mohammed Aasim Subairdeen, Navaneetha Krishnan Muthukrishnan","doi":"10.1177/09544119251325115","DOIUrl":"https://doi.org/10.1177/09544119251325115","url":null,"abstract":"<p><p>A tremor is a neurological disorder that results in trembling or shaking in one or more body parts. A thorough literature review was conducted to investigate the methods for suppressing tremors. We looked for articles published between 1995 and 2024 in the databases CINAHL (Cumulative Index to Nursing and Allied Health Literature), PubMed, Medline, Embase, Scopus, and Cochrane. Two thousand two hundred fifty distinct items were discovered after an extensive search. Based only on the title, 250 were included. Two hundred papers were deemed ineligible after the abstracts were assessed. The remaining 26 articles were shortlisted after screening titles and abstracts and categorized based on treatment methods for hand tremors. According to the study's findings, deep brain stimulation (DBS) and electrical stimulation both reduced tremors considerably. It was also evident that attenuation systems and passive devices lessen the effects of tremors; target tracking tasks can lessen physiological tremors in postural posture; ET may have better hand functions after cold water treatment than warm water or at baseline; and targeted ultrasound thalamotomy is an effective treatment for ET, as it improved quality of life (QoL) significantly. Additionally, the design, development, and evaluation of wearable devices and pharmaceutical interventions for tremor suppression were investigated in detail. The main objective was to perform a comparative analysis of the merits and demerits of both treatment methodologies in terms of functional outcomes, users' comfort, and side effects. The review highlights wearable devices as a beneficial option for tremor suppression, offering comfort, safety, and advanced technology over pharmaceutical intervention methodologies.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251325115"},"PeriodicalIF":1.7,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning and robotics enabled approach for audio based emotional pragmatics deficits identification in social communication disorders.","authors":"Muskan Chawla, Surya Narayan Panda, Vikas Khullar","doi":"10.1177/09544119251325331","DOIUrl":"https://doi.org/10.1177/09544119251325331","url":null,"abstract":"<p><p>The aim of this study is to develop Deep Learning (DL) enabled robotic systems to identify audio-based emotional pragmatics deficits in individuals with social pragmatic communication deficits. The novelty of the work stems from its integration of deep learning with a robotics platform for identifying emotional pragmatics deficits. In this study, the proposed methodology utilizes the implementation of machine and DL-based classification techniques, which have been applied to a collection of open-source datasets to identify audio emotions. The application of pre-processing and converting audio signals of different emotions utilizing Mel-Frequency Cepstral Coefficients (MFCC) resulted in improved emotion classification. The data generated using MFCC were used for the training of machine or DL models. The trained models were then tested on a randomly selected dataset. DL has been proven to be more effective in the identification of emotions using robotic structure. As the data generated by MFCC is of a single dimension, therefore, one-dimensional DL algorithms, such as 1D-Convolution Neural Network, Long Short-Term Memory, and Bidirectional-Long Short-Term Memory, were utilized. In comparison to other algorithms, bidirectional Long Short-Term Memory model has resulted in higher accuracy (96.24%), loss (0.2524 in value), precision (92.87%), and recall (92.87%) in comparison to other machine and DL algorithms. Further, the proposed model was deployed on the robotic structure for real-time detection for improvement of social-emotional pragmatic responses in individuals with deficits. The approach can serve as a potential tool for the individuals with pragmatic communication deficits.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251325331"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel preoperative prosthetic position planning algorithm for total hip arthroplasty based on the no-impingement principle: A case study.","authors":"Tao Feng, Hao Tang, Xiaogang Zhang, Yali Zhang, Yixin Zhou, Zhongmin Jin","doi":"10.1177/09544119251319960","DOIUrl":"https://doi.org/10.1177/09544119251319960","url":null,"abstract":"<p><p>Most preoperative planning calculations of impingement-free range of motion (IFROM) and impingement-free safe zone (IFSZ) rarely consider non-standard shaped prostheses and bony impingement (BI) for total hip arthroplasty (THA). This research developed a novel algorithm that considers BI, prosthetic impingement, pelvic tilt angle (<i>PT</i>) in the sagittal plane, and non-standard-shaped hip prostheses. This research aimed to investigate the effect of BI and <i>PT</i> on hip IFROM, IFSZ, and the BI rate. Using this algorithm to calculate a case, we found that when considering BI, (1) the upper limit of the hip IFROM was decreased, and the different <i>PT</i> affected the upper limit of the hip IFROM of various movements; (2) the BI rate of the flat-rim liner in standing and sitting postures were 54.6% and 67%; and (3) the maximum IFSZ size of the flat-rim liner was reduced by 12%, the reduction rate of the combined pelvic position with a non-zero IFSZ size was 83.2% for the flat-rim liner. Consideration of BI further reduces the IFROM, the IFSZ size, and the number of the combined position of the pelvis with a non-zero IFSZ size of the hip joint. Importantly, this algorithm provides a reliable tool for personalized prosthesis positioning for THA. This algorithm has excellent applications in personalized surgical planning and surgical robotics.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251319960"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis and optimization of cortical bone drilling process based on stochastic optimization.","authors":"Ghodratollah Taheri, Reza Saeidi Abueshaghi, Farbod Setoudeh, Vahid Tahmasbi, Mohammad Mohammadian","doi":"10.1177/09544119251321134","DOIUrl":"https://doi.org/10.1177/09544119251321134","url":null,"abstract":"<p><p>The process of bone drilling is essential in orthopedic surgery and fracture treatment, involving the machining of anisotropic composite materials that exhibit significant hardness and strength. This technique is commonly employed to access underlying tissues, place implants, or remove damaged tissue. However, the challenging nature of this process can lead to high shear forces and elevated temperatures, which pose a risk of thermal necrosis - a condition that damages bone tissue due to excessive heat generated during surgery. When drilling temperatures exceed the critical threshold of 47°C, it can result in the death of bone tissue cells, contributing to micro-cracks, and layering within the bone structure. This study examines the effects of key drilling parameters - rotational speed, feed rate, and tool diameter - and is divided into two main sections: laboratory experiments and statistical modeling using Analysis of Variance (ANOVA). A sensitivity analysis was also performed to assess how optimal parameter values influence output temperature. The results emphasize the significance of temperature control during the drilling process and demonstrate that optimizing these parameters greatly improves bone drilling procedures.To manage temperature effectively, researchers employed the Simultaneous Perturbation Stochastic Approximation (SPSA) optimization algorithm, recognized for its high accuracy and efficiency. Laboratory drilling tests were carried out using the optimal values derived from this optimization process, confirming its effectiveness. Additionally, the findings indicate that temperature fluctuations are influenced by the type of bone, its softness or hardness, and the inherent properties of anisotropic composite materials, which can also contribute to higher temperatures during drilling. Overall, this research underscores the vital importance of parameter optimization in enhancing outcomes in orthopedic applications and reducing the risks associated with thermal necrosis.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251321134"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rings in Taylor Spatial Frame: Mechanical testing and finite element analysis.","authors":"Ahmad Zamani, Michalis Zenios, S Olutunde Oyadiji","doi":"10.1177/09544119251321128","DOIUrl":"10.1177/09544119251321128","url":null,"abstract":"<p><p>Taylor Spatial Frame (TSF) is a type of hexapod external ring fixation system. TSF rings are supplied as half rings, whole full rings and two third rings in different sizes. In this work, these components as well as bolted full rings made of two half rings were tested in compression in two or three directions. Tests were simulated by Finite Element (FE) method using 3D solid elements, which were validated against the experimental results. Load-deflection curves and values for stiffness and ultimate loads are presented for each case from both tests and FE analyses. Load-stiffness curves are also presented for each test. The followings were demonstrated by the results: (1) a significant difference between bolted and whole full rings in their respective stiffness behaviour, the clear advantage being with the whole full rings, (2) a variation in stiffness of bolted rings when loaded across their different diameters, (3) a potential problem in the TSF rings: having the same cross section and thickness, smaller rings are stronger than larger ones, whereas in fact the larger ones ought to be stronger due to patient's weight and that (4) the lowest stiffness was exhibited when a 2/3 ring was loaded parallel to the line joining its open ends.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251321128"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A proposal to analyze muscle fiber type composition in the soleus muscle of untrained subjects and sprinters using surface EMG signals.","authors":"Venugopal Gopinath, Manuskandan Swaminathan Ramakrishnan, Remya R Nair, Ramakrishnan Swaminathan","doi":"10.1177/09544119251321129","DOIUrl":"https://doi.org/10.1177/09544119251321129","url":null,"abstract":"<p><p>Muscle fiber type proportion is a key determinant of fatigue, force generation, and functions of different skeletal muscles. Analysis of muscle fiber type composition aids in the assessment of athletic abilities and individualization of training methods. This study attempts to non-invasively analyze the muscle fiber type composition in the soleus (SOL) of untrained subjects (UT) and sprinters (SP) using surface electromyography-based time-frequency analysis. Signals are recorded from both groups during an isometric calf raise test with loads until fatigue. Filtered signals are segmented into epochs of 1-s duration and processed using a reassigned Morlet scalogram. Four time-frequency features namely averaged frequency, squared frequency bandwidth, averaged time, and squared time duration are extracted from the reassigned distribution and are subjected to linear regression analysis. A fiber-type-specific reassigned profile is noticed for UT and SP reflecting their distinct muscle composition during their non-fatigue and fatigue states. The regression parameters namely slope, intercept, and Adjusted R-square values are higher for the signals of SP indicating their fast-fatigue characteristics. Greater variation of features during fatigue is noticed in the signals of UT compared to SP. Among the features, the squared time duration exhibits the highest significance of <i>p</i> = 8.75E-07 in differentiating the signals of UT and SP during the non-fatigue state. Thus, the proposed approach is found suitable for analyzing the fiber type differences in both subject groups. This work may be further extended in sports biomechanics for studying the fiber-type transformations in muscles due to different athletic training strategies.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119251321129"},"PeriodicalIF":1.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic pain classification using PPG and ECG parameters selected via hybrid feature selection.","authors":"Jia-Hao Cai, De-Fu Jhang, Shih-Che Hung, Yu-Ting Tai, Chia-Yu Hsu, Chiung-Cheng Chuang","doi":"10.1177/09544119241309424","DOIUrl":"https://doi.org/10.1177/09544119241309424","url":null,"abstract":"<p><p>Current chronic pain intensity assessment methods are large based on self-description, which is the gold-standard in clinical practice. However, for patients who lack communication ability or consciousness, this challenging task falls on medical staff. Our study aimed to develop a pain intensity classification system to perform this task automatically. Electrocardiogram and photoplethysmography (PPG) recordings from 43 patients with pain were analyzed with recordings from 20 healthy volunteers as a control group. A numerical rating scale was derived to assess pain intensity, which was divided into four categories of no pain, low pain, moderate pain, and severe pain as specific labels. To explore the robustness of PPG and heart rate variability (HRV) features, a hybrid feature selection (HFS) method was applied to identify important indicators based on majority rule. Additionally, a multi-class support vector machine (SVM) was utilized for classification with 10-fold cross validation. The overall estimation accuracy of the SVM for the four pain intensity levels was approximately 74.6%. It was determined that PPG and HRV features with HFS can provide sufficient information to discriminate different pain intensities in myofascial chronic pain patients. Additionally, our study yielded a novel perspective regarding the trends of PPG features in clinical practice.</p>","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"9544119241309424"},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143503761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}