Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine最新文献_第2页

Development of small bone implants using a mean shape bone in a porcine model for carpal bone replacement. 在猪模型腕骨置换中使用平均形状骨的小骨植入物的发展。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-24 DOI: 10.1177/09544119251355382

Quianna M Vaughan, Amy M Morton, Douglas Moore, Edward Akelman, Joseph J Crisco

{"title":"Development of small bone implants using a mean shape bone in a porcine model for carpal bone replacement.","authors":"Quianna M Vaughan, Amy M Morton, Douglas Moore, Edward Akelman, Joseph J Crisco","doi":"10.1177/09544119251355382","DOIUrl":"10.1177/09544119251355382","url":null,"abstract":"The development of innovative small bone replacements for the human wrist has been partially limited by the lack of a suitable preclinical animal model. This study explores the feasibility of using the Yucatan minipig (YMP) as a preclinical model for small bone replacement. Implants for the radial carpal bone (RCB), homologous to the human scaphoid, were developed for a pilot in vivo animal study. RCB size (volume, bounding box dimensions) was quantified (n = 35), and relationships between animal age, weight, and RCB volume were investigated. Bounding box dimensions were also analyzed relative to RCB volume. A mean-shaped RCB model was generated using ShapeWorks Studio and scaled to create a set of implants. These implants were evaluated in a pilot in vivo study, where the distances between the explanted bone surface and both the predicted and surgeon-selected implant surfaces were recorded for each animal. Predicted implant distances (0.8 ± 0.2 mm), were larger (p < 0.001) than surgeon-selected implant distances (0.4 ± 0.1 mm) in three animals. In one animal, the predicted implant distances (0.3 ± 0.2 mm) were smaller (p < 0.0001) than the surgeon-selected implant distances (0.5 ± 0.3 mm). The set of implants generated provided the surgeon with options suitable for the range of animals in the in vivo study. This study presents a novel approach to generating small bone replacements by scaling a mean-shaped bone in a porcine model and further evaluates the YMP as a preclinical model for small bone replacement in the human wrist.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"755-765"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Critical review on additive manufacturing based biomedical and biosensors application. 基于增材制造的生物医学和生物传感器应用综述。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-08-12 DOI: 10.1177/09544119251355052

R Raghavendra Rao, B N Sharath, S Pradeep, M Hareesha, D J Navaneet

{"title":"Critical review on additive manufacturing based biomedical and biosensors application.","authors":"R Raghavendra Rao, B N Sharath, S Pradeep, M Hareesha, D J Navaneet","doi":"10.1177/09544119251355052","DOIUrl":"10.1177/09544119251355052","url":null,"abstract":"The domains of biomedical engineering and biosensors have been revolutionized by additive manufacturing, commonly referred to as 3D printing. This study delves into the various ways additive printing has been used in these fields, showcasing its role in creating biosensor parts, implants, tissue engineering scaffolds, and medical equipment. The production of typical prosthetics and implants has been revolutionized by additive manufacturing. It allows for the manufacture of complicated geometries with a high degree of precision and personalization, which in turn improves clinical results and patient care. Additionally, innovative diagnostic tools have been developed through the combination of biosensor technologies with additive manufacturing. These tools can identify infections, physiological factors, and biomarkers with a level of sensitivity and specificity that has never been seen before. This review discusses the present and prospects of additive manufacturing for biomedical and biosensor applications, as well as the state-of-the-art techniques and materials used in this sector. It also analyzes the ongoing obstacles in this area. Additive manufacturing has enormous potential to transform bio sensing technology and healthcare delivery, opening the door to novel approaches to difficult medical problems.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"721-735"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144837476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a radiation-free magnetic guidance device for distal screw placement in intramedullary nails. 用于髓内钉远端螺钉置入的无辐射磁导向装置的研制。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-08-21 DOI: 10.1177/09544119251357640

Yi-Chih Chen, Wen-Tzu Chen, Peng-Lin Yeh, Po-Jen Shih

{"title":"Development of a radiation-free magnetic guidance device for distal screw placement in intramedullary nails.","authors":"Yi-Chih Chen, Wen-Tzu Chen, Peng-Lin Yeh, Po-Jen Shih","doi":"10.1177/09544119251357640","DOIUrl":"https://doi.org/10.1177/09544119251357640","url":null,"abstract":"This study developed a practical device for guiding distal interlocking screws during intramedullary nail fixation, aiming to address issues associated with the conventional free-hand approach using fluoroscopy. The objectives were to attain precision, reduce radiation exposure, and ease of operation. A small cylindrical magnet was embedded in the distal screw hole to emit signals for positioning. Due to the magnet's relatively weak magnetic force, especially in clinical settings with obese patients, the required long sensing distance is significant, making it susceptible to interference from the Earth's magnetic field. Therefore, three magnetic sensors were integrated to detect subtle magnetic changes: two sensors detect the position and tilt of the magnet, while the third sensor identifies the Earth's magnetic field. Consequently, this handheld device can freely rotate and tilt in three-dimensional space to accommodate the surgical site as required by the patient. Testing was conducted on porcine legs using a nonferromagnetic intramedullary nail and a magnet. Two validation methods were employed: passing a cotton rope through the drilled hole and using colored tape to assess drill bit accuracy. In tests, all targets of passing through the intramedullary nail hole were successfully achieved, with high accuracy rate (position accuracy of 91%-96%). Since this device is self-contained, sterilization can be achieved using an external plastic protective cover. The developed device offers a safe, accurate, and efficient radiation-free solution for distal screw placement, with strong clinical applicability and ease of use.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"239 8","pages":"775-787"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and development of an Orthodontic Torque Simulator for the measurement of tie-wing deformation. 正畸扭矩模拟器系翼变形测量的设计与开发。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-15 DOI: 10.1177/09544119251352071

Subramanian Sundar, Pandurangan Harikrishnan, Devadhas Kingsly Jeba Singh

{"title":"Design and development of an Orthodontic Torque Simulator for the measurement of tie-wing deformation.","authors":"Subramanian Sundar, Pandurangan Harikrishnan, Devadhas Kingsly Jeba Singh","doi":"10.1177/09544119251352071","DOIUrl":"10.1177/09544119251352071","url":null,"abstract":"In fixed appliances, archwire rotation transfer the applied forces to the bracket which causes repositioning of the crown or roots of a tooth. Understanding this process is difficult due to the complex geometry and miniature dimensions of the bracket and archwire. In this work, an experimental setup was designed, and fabricated to measure the torque induced in the bracket-archwire-ligature combinations and to find the tie-wing deformation for varying archwire rotations. The developed setup has four components, namely, fixture assembly to position and hold the bracket-archwire-ligature combination; torque measurement system; vision capture system to calculate the deformation of bracket tie-wings; and drive system to rotate the archwire. The fabricated setup was validated with different sizes of stainless steel (SS) bracket-archwire-ligature combinations. The developed experimental setup was used to measure the torque and tie-wing deformation of 0.018″ and 0.022″ conventional brackets with three different archwires and ligatures and 15 trials each. The clinically effective torque angle required for the orthodontic treatments were analyzed along with tie-wing deformation. The test results were compared with the literature and validated. The torque moment of both 0.018″ and 0.022″ bracket systems increased as the archwire width and archwire rotation increased. The torque moment with SS wire ligation was significantly larger than that of elastic ligature for all the archwires tested in both systems. Each bracket-archwire-ligature combination tested had shown significantly different torque characteristics and tie-wing deformations. This study would be of clinical importance to find the tie-wing deformation along with torque on various bracket-archwire-ligature combinations.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"815-826"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial fixation of metallic wedge-augmented versus angled BIO reverse shoulder arthroplasty techniques: A finite element study. 金属楔形增强与角度BIO反向肩关节置换术的初始固定：有限元研究。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-24 DOI: 10.1177/09544119251356213

Mariana Lopes, Carlos Quental, Marco Sarmento, João Folgado

{"title":"Initial fixation of metallic wedge-augmented versus angled BIO reverse shoulder arthroplasty techniques: A finite element study.","authors":"Mariana Lopes, Carlos Quental, Marco Sarmento, João Folgado","doi":"10.1177/09544119251356213","DOIUrl":"10.1177/09544119251356213","url":null,"abstract":"Augmented techniques in the reverse total shoulder arthroplasty (rTSA) have emerged to treat large asymmetric glenoid bone defects and restore shoulder function. However, whether metallic wedge-augmented (W-AUG-rTSA) and angled bony increased-offset (angled BIO-rTSA) rTSA techniques provide equivalent implant fixation remains unclear. This study aimed to directly compare the initial fixation of W-AUG-rTSA and angled BIO-rTSA in a 15° retroverted glenoid, while also assessing the impact of graft stiffness and the number of peripheral screws. Finite element models were developed considering compressive and inferior-to-superior shear loads. Micromotions at the bone-implant interface were compared between the techniques, considering variations in the number of peripheral screws (2 vs 4) and graft stiffness in the angled BIO-rTSA (96 MPa and 1.3 GPa to simulate different bone qualities, and 2.5 GPa to simulate a porous metal wedge as used in the W-AUG-rTSA). The W-AUG-rTSA and angled BIO-rTSA achieved, respectively, maximum micromotions of 63.5 µm and 47.4-65.0 µm (depending on graft stiffness). Assuming a bone ingrowth threshold of 50 µm, 9% and 0%-4% of the bone-implant interface exceeded this threshold for the W-AUG-rTSA and angled BIO-rTSA techniques, respectively, when 4 peripheral screws were used. These results suggest that both augmentation techniques can likely achieve good initial fixation under this screw configuration. Although changes in graft stiffness affected the micromotion distribution in the angled BIO-rTSA, their overall impact on initial fixation was limited. Reducing the number of peripheral screws to 2 resulted in a substantial increase in interface nodes exceeding the 50 µm threshold in both techniques.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"766-774"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of compression application and exercise on interface pressure (IP) gradients in healthy volunteers. 压缩和运动对健康志愿者界面压力梯度的影响。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-08-15 DOI: 10.1177/09544119251363649

James B Cox, Suzie Ehmann, Aidan J Quinn, Hayden E Cagle, John D DesJardins

{"title":"The effect of compression application and exercise on interface pressure (IP) gradients in healthy volunteers.","authors":"James B Cox, Suzie Ehmann, Aidan J Quinn, Hayden E Cagle, John D DesJardins","doi":"10.1177/09544119251363649","DOIUrl":"10.1177/09544119251363649","url":null,"abstract":"Lower extremity compression is effective in treating various vascular and wound conditions. Assessment of IP variations along limb length and under different compression applications are limited. This work quantified both local and gradient in vivo IP map with a piezoresistive (PR) sensor under three different compression applications when applied to the right leg of forty healthy subjects (n = 40). Compression applications included elastic stockinette, EdemaWear (EW), a pre-packaged compression set, CoFlex TLC (CF) and a combination application, CF applied over EW (Both = BO). Results showed statistical variations in local pressures and pressure gradients that varied by condition, body position, and post 10 min of exercise. Immediately post application significant differences between all compression conditions were observed at both distal and proximal measurement points, ranging from 10.8 ± 4.2 mmHg for supine EW to 38.2 ± 10.7 mmHg for standing BO. A non-uniform reduction in IP was observed post a brief period of wear under CF and BO, but not EW. The largest decrease was observed at the proximal measurement point under BO (37% reduction). Rate of change in IP proximal to distal ranging from -2.4 to 3.4 mmHg/in. Vertical patterning that mirrored the structural design of the EW was observed in some, but not all, of the pressure maps for the BO application only. The use of the PR sensor for capturing in vivo IP profiles may provide a more comprehensive understanding of the compression effect, highlighting the importance of considering variation in IP across the limb over a period of wear.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"827-839"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating fixation techniques to prevent subsidence in cervical corpectomy models using low and high-density polyurethane blocks. 评估使用低密度和高密度聚氨酯块防止颈椎椎体切除术模型下沉的固定技术。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-27 DOI: 10.1177/09544119251355721

Tolga Türkmen, Aydemir Kale, Yunus Uslan, Teyfik Demir

{"title":"Evaluating fixation techniques to prevent subsidence in cervical corpectomy models using low and high-density polyurethane blocks.","authors":"Tolga Türkmen, Aydemir Kale, Yunus Uslan, Teyfik Demir","doi":"10.1177/09544119251355721","DOIUrl":"https://doi.org/10.1177/09544119251355721","url":null,"abstract":"Subsidence is a common complication, especially in multisegment corpectomies. In addition to the characteristics of the cage, fixation method is also an effective means of preventing subsidence. We compared three different fixation methods used after the cage placement: Anterior fixation (AF), posterior fixation (PF), and circumferential fixation (CF). Low-density (LDB) and high-density (HDB) polyurethane blocks were used to mimic osteoporotic and normal bone, respectively. Five models within the groups loaded flexion-extension testing, and maximum compressive loads (MCL), bending moment and stiffness were determined in static tests. Subsequently, the specimens were subjected to dynamic fatigue tests then the amount of subsidence was calculated. The MCL and stiffness differences between AF, PF, and CF in the LDB were statistically significant, decreasing CF, PF, AF, respectively. In the HDB group, the difference in MCL between AF, PF, and CF was significant, decreasing from CF to PF to AF, respectively. The differences between the stiffness of these models were statistically significant, from high to low CF, PF, AF. The subsidence of AF, PF and CF in the LDB were 2.3 ± 1.59 mm, 7.5 ± 1.58 mm, and 0.65 ± 0.10 mm, respectively. In this group, CF is more successful in preventing subsidence than AF and PF. Subsidence of less than 1 mm was observed in all models in the HDB. This study suggests that AF is as effective as other methods in preventing subsidence following two-level corpectomy in patients with high bone quality. In those with low bone quality, CF could provide more stable fixation and may be more reliable in preventing subsidence and potential instrumentation failure.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"239 8","pages":"746-754"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of porous customized Ti-6Al-4V cranial implant manufactured by laser beam powder bed fusion. 激光粉末床融合制备多孔定制Ti-6Al-4V颅骨种植体的研制。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-07-27 DOI: 10.1177/09544119251351733

Mihrigul Ekşi Altan, Alperen Acar, Seyhan Özen, Yeliz Güldorum, Eren Külle, Berke Apaydınlı, Abdulkadir Günay, Meltem Eryildiz

{"title":"Development of porous customized Ti-6Al-4V cranial implant manufactured by laser beam powder bed fusion.","authors":"Mihrigul Ekşi Altan, Alperen Acar, Seyhan Özen, Yeliz Güldorum, Eren Külle, Berke Apaydınlı, Abdulkadir Günay, Meltem Eryildiz","doi":"10.1177/09544119251351733","DOIUrl":"https://doi.org/10.1177/09544119251351733","url":null,"abstract":"Customized cranial implants play a crucial role in neurosurgery, serving to restore cranial integrity and protect the underlying brain tissue after trauma or surgical intervention. Ti-6Al-4V cranial implants exhibit high mechanical strength; however, their solid forms can be excessively heavy and possess a high elastic modulus, leading to stress shielding effects. This study focuses on designing a cranial implant utilizing computer tomography data, incorporating different lattice and porous structures to optimize weight and mechanical performance. The analysis, conducted with nTop software, compared displacement and von Mises stress values across different structures. The isotruss lattice structure emerged as the most effective, achieving a weight reduction of approximately 50% while maintaining a von Mises stress of 40 MPa. Following the computational analysis, Laser Beam Powder Bed Fusion (PBF-LB) was employed to fabricate the isotruss implant and the compression test was performed to mimic the cranial implant under realistic conditions. The isotruss lattice cranial implant exhibited a remarkable load-bearing capacity of up to 18,000 N while achieving a 50% weight reduction compared to the solid implant, indicating that this lightweight structure not only offers high-performance load-bearing capabilities but also shows great potential for use in surgical applications.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":"239 8","pages":"736-745"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PPEA: Personalized positioning and exposure assistant based on multi-task shared pose estimation transformer. PPEA：基于多任务共享姿态估计转换器的个性化定位和曝光助手。

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-08-13 DOI: 10.1177/09544119251359978

Jie Zhao, Jianqiang Liu, Chunfeng Yang, Hui Tang, Yang Chen, Yudong Zhang

{"title":"PPEA: Personalized positioning and exposure assistant based on multi-task shared pose estimation transformer.","authors":"Jie Zhao, Jianqiang Liu, Chunfeng Yang, Hui Tang, Yang Chen, Yudong Zhang","doi":"10.1177/09544119251359978","DOIUrl":"10.1177/09544119251359978","url":null,"abstract":"Hand and foot digital radiography (DR) is an indispensable tool in medical imaging, with varying diagnostic requirements necessitating different hand and foot positionings. Accurate positioning is crucial for obtaining diagnostically valuable images. Furthermore, adjusting exposure parameters such as exposure area based on patient conditions helps minimize the likelihood of image retakes. We propose a personalized positioning and exposure assistant capable of automatically recognizing hand and foot positionings and recommending appropriate exposure parameters to achieve these objectives. The assistant comprises three modules: (1) Progressive Iterative Hand-Foot Tracker (PIHFT) to iteratively locate hands or feet in RGB images, providing the foundation for accurate pose estimation; (2) Multi-Task Shared Pose Estimation Transformer (MTSPET), a Transformer-based model that encompasses hand and foot estimation branches with similar network architectures, sharing a common backbone. MTSPET outperformed MediaPipe in the hand pose estimation task and successfully transferred this capability to the foot pose estimation task; (3) Domain Expertise-embedded Positioning and Exposure Assistant (DEPEA), which combines the key-point coordinates of hands and feet with specific positioning and exposure parameter requirements, capable of checking patient positioning and inferring exposure areas and Regions of Interest (ROIs) of Digital Automatic Exposure Control (DAEC). Additionally, two datasets were collected and used to train MTSPET. A preliminary clinical trial showed strong agreement between PPEA's outputs and manual annotations, indicating the system's effectiveness in typical clinical scenarios. The contributions of this study lay the foundation for personalized, patient-specific imaging strategies, ultimately enhancing diagnostic outcomes and minimizing the risk of errors in clinical settings.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"788-801"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144837478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical properties of Palacos^® MV bone cements containing magnetic glass-ceramic particles. 含有磁性微晶玻璃颗粒的Palacos®MV骨水泥的力学性能

IF 1.5 4区医学

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Pub Date : 2025-08-01 Epub Date: 2025-08-18 DOI: 10.1177/09544119251357342

Fatma Ozdemir, Iain Evans, Oana Bretcanu

{"title":"Mechanical properties of Palacos® MV bone cements containing magnetic glass-ceramic particles.","authors":"Fatma Ozdemir, Iain Evans, Oana Bretcanu","doi":"10.1177/09544119251357342","DOIUrl":"10.1177/09544119251357342","url":null,"abstract":"Polymethylmethacrylate (PMMA) is the most used bone cement in orthopaedic surgery for the fixation of prosthetic components or filling bone defects. PMMA bone cements containing magnetic particles have been explored for the treatment of bone cancers using magnetic induction hyperthermia. In this study, different formulations of magnetic bone cements were developed by mixing up to 40 wt% of magnetic glass-ceramics with Palacos® MV, a commercial PMMA bone cement with medium viscosity. Mechanical properties of these magnetic bone cements were investigated and compared to the non-magnetic commercial Palacos® MV cement, which was used as control. Setting time, setting temperature, compressive strength, bending strength and bending modulus of these magnetic bone cements were evaluated using the ISO 5833:2002 standard guidelines. Vickers hardness tests were carried out using ASTM E384-22 standard. Setting time increased with the amount of magnetic glass-ceramic in the bone cement. Setting temperatures of magnetic cements and non-magnetic control are similar. All magnetic bone cements have the average compressive strength above 70 MPa and the average bending modulus above 1.8 GPa, and meet the requirements of the ISO 5833:2002 standard. Only magnetic cements containing up to 30 wt% of magnetic glass-ceramic have the average bending strength above 50 MPa and comply with the ISO 5833:2002 standard requirement. All magnetic bone cements have Vickers hardness higher than the control cements. Thus, magnetic cements containing up to 30 wt% of magnetic glass-ceramic have the potential to be used for the treatment of bone cancers.","PeriodicalId":20666,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine","volume":" ","pages":"840-854"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0