Preventive Nutrition and Food Science最新文献_第2页

Application of Honey from Hedera rhombea as a Sugar Substitute to Design Functional Cookies for Controlling Carbohydrate Digestion. 应用菱形蜜代糖设计控制碳水化合物消化的功能性饼干。

IF 2.5

Preventive Nutrition and Food Science Pub Date : 2025-08-31 DOI: 10.3746/pnf.2025.30.4.391

Hyeonbeom Kim, Soungcheol Baek, Jongbin Lim

{"title":"Application of Honey from Hedera rhombea as a Sugar Substitute to Design Functional Cookies for Controlling Carbohydrate Digestion.","authors":"Hyeonbeom Kim, Soungcheol Baek, Jongbin Lim","doi":"10.3746/pnf.2025.30.4.391","DOIUrl":"10.3746/pnf.2025.30.4.391","url":null,"abstract":"In this study, honey from Hedera rhombea was used as a sugar substitute in cookie-making to design functional cookies for controlling carbohydrate digestion. Honey from H. rhombea contained glucose (0.56±0.11 mg/mg), fructose (0.27±0.06 mg/mg), and phenolic compounds (46.61±0.05 mg gallic acid equivalents/100 g). When honey from H. rhombea was used as a sugar substitute in the cookie dough, it decreased the dough stability and increased the degree of softening from the farinograph compared with the control dough, which implies a weaker gluten network formation. Moreover, the honey influenced the baking performance by decreasing the spread ratio and hardness, resulting in the production of softer cookies with a dark yellow color. Finally, the cookies prepared with honey exhibited reduced amounts of reducing sugars against α-amylase because of the antioxidant activity of phenolic compounds within the honey, indicating slower carbohydrate digestion. These results provide insights into how to use honey as a sugar substitute to design functional foods for modulating the postprandial glycemic response.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 4","pages":"391-398"},"PeriodicalIF":2.5,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Analysis of Fucosyllactose-Induced Changes in Adult Gut Microbiota and Short-Chain Fatty Acid Production Using the Simulator of Human Intestinal Microbial Ecosystem Model. 利用人体肠道微生物生态系统模型模拟器对比分析焦酰基乳糖诱导的成人肠道菌群变化和短链脂肪酸生成

IF 2.5

Preventive Nutrition and Food Science Pub Date : 2025-08-31 DOI: 10.3746/pnf.2025.30.4.331

Yohei Sato, Masaya Kanayama, Shiori Nakajima, Yosuke Komatsu, Takeshi Kokubo

{"title":"Comparative Analysis of Fucosyllactose-Induced Changes in Adult Gut Microbiota and Short-Chain Fatty Acid Production Using the Simulator of Human Intestinal Microbial Ecosystem Model.","authors":"Yohei Sato, Masaya Kanayama, Shiori Nakajima, Yosuke Komatsu, Takeshi Kokubo","doi":"10.3746/pnf.2025.30.4.331","DOIUrl":"10.3746/pnf.2025.30.4.331","url":null,"abstract":"As the third most abundant solid component of human milk, human milk oligosaccharides (HMOs) exert well-known effects on the infant gastrointestinal tract, including promoting Bifidobacterium growth and preventing pathogen infection. However, the effects of HMOs on the adult gut microbiome remain unknown. In this study, we examined the effects of 2'-fucosyllactose (2'-FL) and 3-fucosyllactose (3-FL), the most abundant HMOs, on the adult gut microbiome using the Simulator of Human Intestinal Microbial Ecosystem (SHIMEⓇ), which can simulate human gastrointestinal conditions. Healthy adult feces were subjected to SHIMEⓇ and incubated with either 2'-FL or 3-FL. The changes in the short-chain fatty acid concentration in feces and the gut microbiota composition were investigated using high-performance liquid chromatography and 16S rRNA gene sequencing, respectively. The addition of 2'-FL or 3-FL altered the microbial composition and increased acetate, propionate, and butyrate concentrations in the adult SHIMEⓇ culture. Remarkably, a difference was observed in the timing of butyrate production because of the addition of 2'-FL and 3-FL. The present findings can help clarify how FLs affect the gut microbiome of Japanese adults and support the development of targeted products.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 4","pages":"331-339"},"PeriodicalIF":2.5,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Takadiastase on the Extraction of Biotin from Plant-Based Foods. Takadiastase对植物性食品中生物素提取的影响。

IF 2.5

Preventive Nutrition and Food Science Pub Date : 2025-08-31 DOI: 10.3746/pnf.2025.30.4.399

Naeun Kim, Yoonjeong Kim, Jihyeon Yu, Eunji Park, Youngmin Choi, Younghwa Kim

引用次数: 0

Role of Lacticaseibacillus rhamnosus GG in the Management of Respiratory Diseases: A Systematic Review and Meta-Analysis. 鼠李糖乳杆菌GG在呼吸道疾病治疗中的作用：系统综述和荟萃分析。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.222

Muhammad Naufal Zuhair, Edward Pandu Wiriansya, Ismail Masyhuri, Muhammad Fakhri, Mochammad Hatta, Irawaty Djaharuddin, Agussalim Bukhari

{"title":"Role of Lacticaseibacillus rhamnosus GG in the Management of Respiratory Diseases: A Systematic Review and Meta-Analysis.","authors":"Muhammad Naufal Zuhair, Edward Pandu Wiriansya, Ismail Masyhuri, Muhammad Fakhri, Mochammad Hatta, Irawaty Djaharuddin, Agussalim Bukhari","doi":"10.3746/pnf.2025.30.3.222","DOIUrl":"10.3746/pnf.2025.30.3.222","url":null,"abstract":"Respiratory diseases represent a significant global health issue. Currently, there is growing interest in using probiotics [e.g., Lacticaseibacillus rhamnosus GG (LGG)] as adjunctive therapies for the management of respiratory diseases. However, the efficacy of LGG in respiratory diseases remains unknown. Therefore, this study aimed to evaluate the effectiveness of LGG in preventing and treating respiratory diseases. A comprehensive literature search was performed using the PubMed, Embase, Cochrane Library, and Scopus databases using keywords related to LGG and respiratory diseases. Studies were selected on the basis of predefined inclusion and exclusion criteria, and data were extracted for qualitative and quantitative analyses. The Cochrane Risk of Bias tool was used to assess the methodological quality of the included studies, and RevMan 5.4 was used to perform the meta-analysis. Out of 155 studies that were initially identified, 13 randomized controlled trials met the inclusion criteria. The meta-analysis showed that LGG intervention, both as a preventive and therapeutic strategy, significantly reduced the incidence of respiratory disease episodes (mean difference: -0.14, 95% confidence interval: -0.27 to -0.01, P=0.03) and mitigated associated symptoms compared with placebo or no intervention. The results of subgroup analyses indicated that LGG was particularly effective in reducing the duration and severity of respiratory infections in children and high-risk populations. However, heterogeneity (I2=62%) was observed, which was likely because of variations in the study design, dosage, and patient populations. These findings suggest that LGG may be a promising adjunctive therapy for respiratory diseases, particularly in preventive settings.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 3","pages":"222-229"},"PeriodicalIF":1.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Lutein with Cancer: A Systematic Review of the Lutein Effects on Cellular Processes Involved in Cancer Progression. 叶黄素与癌症的关系：叶黄素对参与癌症进展的细胞过程的影响的系统综述。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.250

Fahmideh Bagrezaei, Sorayya Kheirouri, Mohammad Alizadeh

{"title":"Association of Lutein with Cancer: A Systematic Review of the Lutein Effects on Cellular Processes Involved in Cancer Progression.","authors":"Fahmideh Bagrezaei, Sorayya Kheirouri, Mohammad Alizadeh","doi":"10.3746/pnf.2025.30.3.250","DOIUrl":"10.3746/pnf.2025.30.3.250","url":null,"abstract":"Lutein belongs to the carotenoid family of xanthophylls, which have antioxidant, anti-inflammatory, and anticancer properties. This study aimed to comprehensively review the interactions between lutein and critical cellular processes that influence cancer progression. A search of electronic databases, including PubMed, Science Direct, Cochrane Library, Web of Science, Scopus, Google Scholar, and Google, was conducted for the keywords \"cancer or tumor or neoplasm or carcinoma\" and \"lutein\" in the titles or abstracts of published research. A total of 47 studies were reviewed, and it was shown that lutein reduced estrogen receptors (2 out of 4 studies), DNA damage (4 out of 8 studies), cancer cell survival (1 out of 1 studies), growth (7 out of 7 studies), and proliferation (19 out of 19 studies) as well as cancer cell invasion, migration, metastasis, and adhesion (2 out of 2 studies), but induced apoptosis (17 out of 17 studies) and cell differentiation (1 out of 1 studies). According to this review, lutein may be effective in suppressing cellular processes involved in cancer progression through a variety of mechanisms.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 3","pages":"250-262"},"PeriodicalIF":1.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kaempferol Inhibits Lipid Accumulation in HepG2 Cells through AMPK-Mediated Autophagy. 山奈酚通过ampk介导的自噬抑制HepG2细胞脂质积累。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.242

Subin Park, Miey Park, Hae-Jeung Lee

{"title":"Kaempferol Inhibits Lipid Accumulation in HepG2 Cells through AMPK-Mediated Autophagy.","authors":"Subin Park, Miey Park, Hae-Jeung Lee","doi":"10.3746/pnf.2025.30.3.242","DOIUrl":"10.3746/pnf.2025.30.3.242","url":null,"abstract":"Metabolic dysfunction-associated steatotic liver disease (MASLD) is closely associated with metabolic syndrome. Currently, it is considered as a global health concern. Kaempferol (a flavonoid) exhibits extensive pharmacological properties, including anti-inflammatory, antioxidant, anticancer, and neuroprotective effects. In the present study, we investigated the effects of kaempferol on free fatty acid (FFA)-induced lipid accumulation in HepG2 cells. To establish an in vitro model of MASLD, we treated the human hepatocellular carcinoma cell line HepG2 with FFAs. Subsequently, we performed Western blot analysis to analyze the expression levels of essential proteins associated with lipogenesis and autophagy. Vital lipogenesis-related proteins (e.g., acetyl-CoA carboxylase, fatty acid synthase, sterol regulatory element-binding protein-1c, CCAAT/enhancer-binding protein alpha, and peroxisome proliferator-activated receptor gamma) were downregulated by kaempferol treatment. Concurrently, the expression of proteins involved in fatty acid oxidation (e.g., carnitine palmitoyltransferase 1 and peroxisome proliferator-activated receptor alpha) was upregulated. These changes indicate that kaempferol promotes a shift toward enhanced fatty acid oxidation and reduced lipogenesis, thereby mitigating lipid accumulation in liver cells. Our findings suggest that kaempferol exerts a protective effect against MASLD by modulating lipid metabolism via autophagy activation.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 3","pages":"242-249"},"PeriodicalIF":1.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing the Nutritional and Microbiological Properties of Fermented Melon Condiment (Ogiri) Using Newbouldia laevis and Icacina trichantha Leaves. 利用新叶和三叶提高甜瓜发酵调味品的营养和微生物特性。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.285

Oluwatoyin Ajoke Oladeji, Clement Olusola Ogidi

{"title":"Enhancing the Nutritional and Microbiological Properties of Fermented Melon Condiment (Ogiri) Using Newbouldia laevis and Icacina trichantha Leaves.","authors":"Oluwatoyin Ajoke Oladeji, Clement Olusola Ogidi","doi":"10.3746/pnf.2025.30.3.285","DOIUrl":"10.3746/pnf.2025.30.3.285","url":null,"abstract":"This study investigated the influence of incorporating Newbouldia laevis and Icacina trichantha leaves into fermented melon condiment using different wrapping materials for fermentation. Moreover, the resulting quality of the condiment was analyzed. The leaves were boiled with melon seeds after removing their pericarp. Subsequently, the boiled leaves were wrapped in Thaumatococcus daniellii. Other portions of the seeds that were not boiled with the leaves were wrapped in T. danielli leaves, aluminum foil paper, and airtight containers. The proximate, mineral, amino acid, microbiological quality, and antioxidant properties of the condiment were determined in accordance with standard procedures. The protein, ash, fat, and glutamic acid contents of the condiment ranged from 25.20% to 34.57%, 2.10% to 3.22%, 14.61% to 28.65%, and 12.30 mg/100 g protein to 13.80 mg/100 g protein, respectively. The incorporation of leaves and fermentation of melon in leaves significantly (P≤0.05) enhanced their antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl (46.30%－65.60%) and ferric reducing antioxidant power (0.22－0.62 µmol/mL Fe2+). Bacillus subtilis, Corynebacterium spp., Lactobacillus acidophilus, and Staphylococcus aureus were isolated from the fermented condiment. The fermented condiment supported the growth of Lactobacillus fermentum with values of 1.80 to 2.80×105 colony-forming units/mL. Moreover, the fermented condiment showed improved microbiological quality, enhanced nutrient content, and profound antioxidant activities. Hence, the bioactive compounds in the leaves can be exploited and incorporated into food products for therapeutic purposes.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 3","pages":"285-294"},"PeriodicalIF":1.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review of the Effects of Psidium guajava and Syzygium cumini Leaves on Diabetes Mellitus. 瓜石榴叶和茴香叶对糖尿病作用的研究综述。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.209

Sukhmanpreet Kaur, Rohit Chaudhary

引用次数: 0

Anti-Androgenic Effect of Soybean Tempeh Extract in the Treatment of Polycystic Ovary Syndrome. 大豆豆豉提取物治疗多囊卵巢综合征的抗雄激素作用。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.263

Cut Raihanah, Yenni Karlina, Saleh Wikarsa, Neng Fisheri Kurniati, Sukrasno Sukrasno

{"title":"Anti-Androgenic Effect of Soybean Tempeh Extract in the Treatment of Polycystic Ovary Syndrome.","authors":"Cut Raihanah, Yenni Karlina, Saleh Wikarsa, Neng Fisheri Kurniati, Sukrasno Sukrasno","doi":"10.3746/pnf.2025.30.3.263","DOIUrl":"10.3746/pnf.2025.30.3.263","url":null,"abstract":"Polycystic ovary syndrome (PCOS), also known as hyperandrogenic anovulation, has been linked to steroidogenic enzyme activity. Previous studies have reported that soybean isoflavones act as inhibitors of these enzymes due to their anti-androgenic properties. This study evaluated the potential anti-androgenic mechanism of soybean tempeh extract in PCOS through both in vivo and in silico approaches. Female Wistar rats were induced with letrozole to model PCOS, followed by treatments with tempeh extract and metformin as a positive control. Serum testosterone, estrous cycle patterns, and weight were assessed. In the in silico study, daidzein and genistein were docked to the androgen receptor (AR) and 17β-hydroxysteroid dehydrogenase (17β-HSD). Treatment with tempeh extract at 250 mg/kg body weight more effectively restored abnormal estrous cycles than metformin. Weight gain and testosterone levels also decreased in this group. Daidzein and genistein bound to AR inhibitor amino acids; however, only genistein showed high binding energy to 17β-HSD inhibitor amino acids. As an anti-androgen, the findings suggest that tempeh extract at 250 mg/kg body weight may serve as a dietary supplement for managing PCOS, potentially via AR inhibition.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 3","pages":"263-273"},"PeriodicalIF":1.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genomic Analysis and Metabolite Profiling of Three Probiotic Bacillus Strains for Potential Application in Aquaculture. 三种潜在应用于水产养殖的益生菌菌株的基因组分析和代谢物谱分析。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-06-30 DOI: 10.3746/pnf.2025.30.3.274

Evgeniya Valer'evna Prazdnova, Vladimir Anatolevich Chistyakov, Nikita Gennadjevich Vasilchenko, Radomir Viktorovich Skripnichenko, Alina Yurievna Gulyaeva, Anna Valentinovna Aleshukina, Iraida Sergeievna Berezinskaya, Dmitriy Vladimirovich Rudoy

{"title":"Genomic Analysis and Metabolite Profiling of Three Probiotic Bacillus Strains for Potential Application in Aquaculture.","authors":"Evgeniya Valer'evna Prazdnova, Vladimir Anatolevich Chistyakov, Nikita Gennadjevich Vasilchenko, Radomir Viktorovich Skripnichenko, Alina Yurievna Gulyaeva, Anna Valentinovna Aleshukina, Iraida Sergeievna Berezinskaya, Dmitriy Vladimirovich Rudoy","doi":"10.3746/pnf.2025.30.3.274","DOIUrl":"10.3746/pnf.2025.30.3.274","url":null,"abstract":"In this study, we investigated the genomic characteristics and bioactive metabolite profiles of three novel Bacillus strains that were isolated from the intestinal tracts of healthy carp (Cyprinus carpio). Strain identification and whole-genome sequencing were performed before analysis. Among the three novel strains, R1 and R4 were classified as Bacillus subtilis, and strain R5 was classified as Bacillus velezensis. Genome mining revealed a repertoire of secondary metabolites, including bacillaene, bacillibactin, bacilysin, difficidin, and fengycin, which likely contribute to the probiotic potential of these strains. The metabolite profiles were further characterized using matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry, with fengycins and bacillibactin specifically isolated and identified. Additionally, the presence of genetic markers associated with antimicrobial resistance was assessed, and these gene profiles were reconstructed. These Bacillus strains represent promising candidates for the development of novel feed additives for aquaculture.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 3","pages":"274-284"},"PeriodicalIF":1.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0