Preventive Nutrition and Food Science最新文献_第10页

Chondroprotective Effects of Ulva prolifera on Osteoarthritis through MAPKs Signaling Inhibition. Ulva prolifera通过MAPKs信号抑制对骨关节炎的软骨保护作用。

Preventive Nutrition and Food Science Pub Date : 2023-03-31 DOI: 10.3746/pnf.2023.28.1.43

Seul Ah Lee, Seul Hee Han, Ji Yun Jang, Bo-Ram Park, Chun Sung Kim

{"title":"Chondroprotective Effects of Ulva prolifera on Osteoarthritis through MAPKs Signaling Inhibition.","authors":"Seul Ah Lee, Seul Hee Han, Ji Yun Jang, Bo-Ram Park, Chun Sung Kim","doi":"10.3746/pnf.2023.28.1.43","DOIUrl":"https://doi.org/10.3746/pnf.2023.28.1.43","url":null,"abstract":"Osteoarthritis (OA) is a typical degenerative disease that mainly appears in the elderly aged 65 and over. OA is characterized by inflammation and decomposition of the cartilage matrix due to irreversible wear and tear. Ulva prolifera, a green macroalgae species, contains polysaccharides, amino acids, polyunsaturated fatty acids, and polyphenols, which are major active components responsible for anti-inflammatory and antioxidant effects. This study evaluated the chondro-protective effect of 30% prethanol extract of U. prolifera (30% PeUP). Rat primary chondrocytes were pre-treated with 30% PeUP for 1 h before interleukin-1β (10 ng/mL) stimulation. The production of nitrite, prostaglandin E2 (PGE2), collagen type II (Col II), and aggrecan (ACAN) were detected by Griess reagent and enzyme-linked immunosorbent assay. The protein expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase (COX)-2, matrix metalloproteinase (MMP)-1, MMP-3, MMP-13, a disintegrin and metalloproteinase with thrombospondin (ADAMTS)-4, ADAMTS-5, and mitogen-activated protein kinases (MAPKs) (extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinase, and p38) were assessed by western blot. Thirty percent of PeUP significantly inhibited the expression of nitrite, iNOS, PGE2, COX-2, MMP-1, MMP-3, MMP-13, ADMATS-4, and ADMATS-5 in interleukin (IL)-1β-stimulated chondrocytes. Moreover, 30% PeUP decreased the IL-1β-induced degradation of Col II and ACAN. Additionally, 30% of PeUP suppressed IL-1β-induced phosphorylation of MAPKs. Therefore, 30% PeUP is a potential therapeutic agent to mitigate OA progression.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/3b/pnfs-28-1-43.PMC10103602.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9311095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sacha Inchi (Plukenetia volubilis L.) Oil Improves Hepatic Insulin Sensitivity and Glucose Metabolism through Insulin Signaling Pathway in a Rat Model of Type 2 Diabetes. 印度树(Plukenetia volubilis L.)油脂通过胰岛素信号通路改善2型糖尿病大鼠肝脏胰岛素敏感性和葡萄糖代谢

Preventive Nutrition and Food Science Pub Date : 2023-03-31 DOI: 10.3746/pnf.2023.28.1.30

Worarat Rojanaverawong, Navinee Wongmanee, Wanthanee Hanchang

{"title":"Sacha Inchi (Plukenetia volubilis L.) Oil Improves Hepatic Insulin Sensitivity and Glucose Metabolism through Insulin Signaling Pathway in a Rat Model of Type 2 Diabetes.","authors":"Worarat Rojanaverawong, Navinee Wongmanee, Wanthanee Hanchang","doi":"10.3746/pnf.2023.28.1.30","DOIUrl":"https://doi.org/10.3746/pnf.2023.28.1.30","url":null,"abstract":"This study aimed to evaluate the role of sacha inchi oil (SI) in alleviating hepatic insulin resistance and improving glucose metabolism by inhibiting oxidative stress and inflammation in a rat model of type 2 diabetes. This model was established by providing a high-fat diet and streptozotocin to the rats, thereby inducing diabetes. The diabetic rats were treated orally with 0.5, 1, and 2 mL/kg body weight (b.w.) of SI or 30 mg/kg b.w. of pioglitazone daily for 5 weeks. Blood and hepatic tissues were used for insulin sensitivity, carbohydrate metabolism, oxidative stress, and inflammatory status assessment. Treatment with SI attenuated hyperglycemia and insulin resistance indices, and improved hepatic histopathological alterations in the diabetic rats in a dose-dependent manner, which is correlated with the decreased serum levels of the liver enzymes, alanine transaminase and aspartate transaminase. SI significantly diminished the hepatic oxidative status of the diabetic rats by inhibiting malondialdehyde and enhancing the antioxidant superoxide dismutase, catalase, and glutathione peroxidase activities. Moreover, pro-inflammatory cytokine levels, including tumor necrosis factor-α and interleukin-6, in the liver of the diabetic rats were significantly decreased by the SI. Furthermore, SI treatment enhanced the hepatic insulin sensitivity of the diabetic rats, as shown by the increased insulin receptor substrate-1 and p-Akt protein expression, decreased phosphoenolpyruvate carboxykinase-1 and glucose-6-phospatase protein expression, and increased hepatic glycogen content. Overall, these findings suggest that SI exerts a potential hepatic insulin-sensitizing effect and an improvement in glucose metabolism in the type 2 diabetic rats, at least in part through enhancing insulin signaling, antioxidant defense, and inhibiting inflammation.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/e0/pnfs-28-1-30.PMC10103599.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9311096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Protein vs. Energy Restriction Impact on Rat Testis' Function, Redox Status, and Histomorphometry. 蛋白质和能量限制对大鼠睾丸功能、氧化还原状态和组织形态学的影响。

Preventive Nutrition and Food Science Pub Date : 2023-03-31 DOI: 10.3746/pnf.2023.28.1.61

Meddah Benabbou, Amine Allaoui, Aït Kaci Meriem Zahzeh, Ahmed Boualga, Touria Zahzeh

{"title":"Protein vs. Energy Restriction Impact on Rat Testis' Function, Redox Status, and Histomorphometry.","authors":"Meddah Benabbou, Amine Allaoui, Aït Kaci Meriem Zahzeh, Ahmed Boualga, Touria Zahzeh","doi":"10.3746/pnf.2023.28.1.61","DOIUrl":"https://doi.org/10.3746/pnf.2023.28.1.61","url":null,"abstract":"This study aimed to evaluate the effects of protein-restricted (PR) and energy restriction (ER) on male repro-ductive function. Eighteen weaning Wistar rats were divided into three groups, and were fed an experimental diet for five months. The first group, a control (C), received a diet containing 20% casein and 1.7×106 J/kg diet. The ER was given 50% less calories vs. C, while the PR group was given a low-protein diet (10% casein). The reproductive function was evaluated on serum and testis using anthropometrical, histological, hormonal, and oxidative parameters. The body weight was reduced by 37% and 40%, respectively, in the PR and ER groups vs. C. In the PR group, the testis relative weight was decreased, whereas that of the seminal vesicles was higher than that of C. The epididymis and prostate relative weights remained unchanged in the three experimental groups. Furthermore, serum testosterone concentrations were respectively 1.4- and 2.8-fold lower in the PR and ER groups vs. C, whereas no significant difference was found in luteinizing hormone and follicle-stimulating hormone levels among the groups. Compared with the C group, thiobarbituric acid reactive substance, carbonyl levels, glutathione, and glutathione reductase activity reduced significantly in PR, and specifically in ER rat's testis, whereas, catalase and superoxide dismutase activities increased. Furthermore, the testis and epididymis examination revealed histological alterations in the PR and ER groups. In conclusion, ER and PR diets could reduce the oxidant markers, even though they may alter the reproductive activity by probably altering testosterone production.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/35/f0/pnfs-28-1-61.PMC10103604.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9311099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Adipogenic and Anti-Obesity Effects of Gongmi Tea and Gongmi So Extract. 工米茶和工米苏提取物的抗脂肪和抗肥胖作用。

Preventive Nutrition and Food Science Pub Date : 2023-03-31 DOI: 10.3746/pnf.2023.28.1.21

Se Jin Jo, Yue Gong, Rui Jiang, Hyunjae Jung, Young Ran Kim

{"title":"Anti-Adipogenic and Anti-Obesity Effects of Gongmi Tea and Gongmi So Extract.","authors":"Se Jin Jo, Yue Gong, Rui Jiang, Hyunjae Jung, Young Ran Kim","doi":"10.3746/pnf.2023.28.1.21","DOIUrl":"https://doi.org/10.3746/pnf.2023.28.1.21","url":null,"abstract":"The prevalence of obesity has been increasing worldwide, and its pathogenesis is closely related to preadipo-cyte differentiation. Because the presence of obesity increases the risk of chronic disease, it is important to decrease exces-sive body fat accumulation. This study aimed to demonstrate the anti-adipogenesis and anti-obesity effects of gongmi tea and gongmi so extract. The 3T3-L1 preadipocyte cell line was stained with Oil red O, and the expression levels of peroxi-some proliferator-activated receptor-γ (PPARγ), adiponectin, and fatty acid-binding protein 4 (FABP4) were evaluated via Western blot analysis. A mouse model of obesity was developed by feeding C57BL/6 male mice a high-fat diet (HFD). Gongmi tea or gongmi so extract was orally administered at a dose of 200 mg/kg for 6 weeks. The mouse body weight was measured weekly during the study period, and the epididymal adipose tissue weight and blood serum were analyzed at the end of the study period. The gongmi tea and gongmi so extract did not exhibit toxicity in mice. Oil red O staining showed that gongmi tea significantly decreased excessive body fat accumulation. In addition, gongmi tea (300 μg/mL) significantly downregulated adipogenic transcription factors, such as PPARγ, adiponectin, and FABP4. In vivo tests indicated that oral administration of gongmi tea or gongmi so extract to C57BL/6 mice with HFD-induced obesity effectively decreased their body weight and epididymal adipose tissue. Gongmi tea and gongmi so extract have potent in vitro anti-adipogenic effects in 3T3-L1 cells and in vivo anti-obesity effects in mice with HFD-induced obesity.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/22/pnfs-28-1-21.PMC10103607.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9311098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical and Chemical Properties of 70% Cocoa Dark Chocolate Mixed with Freeze-Dried Arazá (Eugenia stipitata) Pulp. 70%可可黑巧克力与冻干阿拉沙混合的理化特性研究(Eugenia stipitata)牙髓

Preventive Nutrition and Food Science Pub Date : 2022-12-31 DOI: 10.3746/pnf.2022.27.4.474

César R Balcázar-Zumaeta, Efraín M Castro-Alayo, Marleni Medina-Mendoza, Lucas D Muñoz-Astecker, Llisela Torrejón-Valqui, Roxana J Rodriguez-Perez, Elizabeth Rojas-Ocampo, Ilse S Cayo-Colca

引用次数: 2

Pluchea indica Leaf Extract Alleviates Dyslipidemia and Hepatic Steatosis by Modifying the Expression of Lipid Metabolism-Related Genes in Rats Fed a High Fat-High Fructose Diet. 梅子叶提取物通过改变高脂高果糖饮食大鼠脂质代谢相关基因的表达来缓解血脂异常和肝脏脂肪变性。

Preventive Nutrition and Food Science Pub Date : 2022-12-31 DOI: 10.3746/pnf.2022.27.4.384

Patcharin Singdam, Jarinyaporn Naowaboot, Laddawan Senggunprai, Kampeebhorn Boonloh, Patchareewan Pannangpetch

{"title":"Pluchea indica Leaf Extract Alleviates Dyslipidemia and Hepatic Steatosis by Modifying the Expression of Lipid Metabolism-Related Genes in Rats Fed a High Fat-High Fructose Diet.","authors":"Patcharin Singdam, Jarinyaporn Naowaboot, Laddawan Senggunprai, Kampeebhorn Boonloh, Patchareewan Pannangpetch","doi":"10.3746/pnf.2022.27.4.384","DOIUrl":"https://doi.org/10.3746/pnf.2022.27.4.384","url":null,"abstract":"This study evaluated the effect of Pluchea indica leaf extract (PIE) on dyslipidemia and lipid accumulation in the liver, emphasizing its molecular mechanisms in regulating lipid metabolism in rats fed a high fat-high fructose diet (HFFD). Male rats were fed HFFD (40% lard and 20% fructose) for ten weeks. They were then divided into four groups receiving distilled water, PIE (100 or 300 mg/kg/d), and pioglitazone (10 mg/kg/d) for a further six weeks, during which the HFFD was continued. After the experiment, fasting blood glucose (FBG), oral glucose tolerance (OGT), serum insulin and leptin levels, lipid profiles, and hepatic triglyceride content were measured. Histological examination and expression levels of lipid metabolism-related genes in the liver were measured. HFFD-fed rats indicated a significantly increased FBG, serum leptin, and homeostasis model assessment of insulin resistance (HOMA-IR) scores with impaired OGT and dyslipidemia compared to rats fed a normal diet. PIE significantly reduced FBG, serum leptin, and HOMA-IR scores and improved OGT. Additionally, PIE significantly improved dyslipidemia and decreased serum-free fatty acids and liver triglyceride content. Hepatic histological examination showed a marked reduction lipid accumulation in relation to HFFD controls. Interestingly, PIE significantly downregulated the expression of lipid synthesis-related genes and upregulated the expression of fatty-acid oxidation-related genes. In conclusion, PIE alleviates dyslipidemia and hepatic steatosis in HFFD rats plausibly by increasing insulin resistance and modifying the gene expression associated with lipid metabolism. PIE may be used as preventive nutrition for dyslipidemia and hepatic steatosis.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/44/e0/pnfs-27-4-384.PMC9843721.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10602768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Applications of Potentiometric Electronic Tongue and Electronic Nose in Sensory Evaluation. 电位法电子舌和电子鼻在感官评价中的最新应用。

Preventive Nutrition and Food Science Pub Date : 2022-12-31 DOI: 10.3746/pnf.2022.27.4.354

Sungeun Cho, Md Shakir Moazzem

{"title":"Recent Applications of Potentiometric Electronic Tongue and Electronic Nose in Sensory Evaluation.","authors":"Sungeun Cho, Md Shakir Moazzem","doi":"10.3746/pnf.2022.27.4.354","DOIUrl":"https://doi.org/10.3746/pnf.2022.27.4.354","url":null,"abstract":"Electronic tongue (e-tongue) and electronic nose (e-nose) have been widely used to determine food products' taste, aroma, and flavor profiles. Several researchers and industries have recently attempted to find relationships between these e-senses and human sensory panels to ultimately replace sensory panels or use them as a viable alternative to timeconsuming and expensive traditional sensory evaluation (e.g., consumer acceptance testing or descriptive sensory analysis). This study investigated the recent applications of e-tongue and e-nose in the food and beverages sectors and their relationships with human sensory panels, including a trained sensory panel and naïve consumers. According to several studies, the e-tongue, e-nose, or a combination of e-tongue and e-nose can be an effective and powerful tool for rapid assessment of sensory profiles and quality detection with significant correlations with human sensory data. These instruments are also often reported to be more sensitive to detect subtle changes/differences that the human panel cannot detect. Future trends and projections of the e-tongue and e-nose with limitations are also discussed.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/64/pnfs-27-4-354.PMC9843717.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10602772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Determination of Aroma Characteristics of Commercial Garlic Powders Distributed in Korea via Instrumental and Descriptive Sensory Analyses. 通过仪器和描述性感官分析确定韩国市场上销售的商用大蒜粉的香味特征

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2022-12-31 DOI: 10.3746/pnf.2022.27.4.464

In-Seo Hwang, Mina K Kim

引用次数: 0

Effect of Fluidized Bed Agglomeration on Rheological and Physical Properties of Soy Protein-Enriched Milk Powder for Dietary Supplementation in Sarcopenia. 流化床团聚对肌少症患者膳食补充大豆蛋白奶粉流变学和物理特性的影响。

Preventive Nutrition and Food Science Pub Date : 2022-12-31 DOI: 10.3746/pnf.2022.27.4.483

Chan Won Seo

{"title":"Effect of Fluidized Bed Agglomeration on Rheological and Physical Properties of Soy Protein-Enriched Milk Powder for Dietary Supplementation in Sarcopenia.","authors":"Chan Won Seo","doi":"10.3746/pnf.2022.27.4.483","DOIUrl":"https://doi.org/10.3746/pnf.2022.27.4.483","url":null,"abstract":"Recently, many elderly people in Korea have been consuming protein-enriched milk powders for dietary supplementation in sarcopenia. In general, protein powders are manufactured using a spray dryer, and their fine particles result in poor instant properties. Fluidized bed agglomeration (FBA) is an effective method for improving the physical properties of protein powders via particle granulation, such as flowability and wettability. Therefore, the effects of FBA on the rheological and physical properties of isolated soy protein (ISP)-enriched skim milk powder (SMP) were investigated in this study. The size of ISP-enriched SMP particles was significantly increased by FBA, leading to changes in the Carr index and Hausner ratio from fair flowability and intermediate cohesiveness to good flowability and low cohesiveness, respectively. The wettability of the granulated particles was also improved by FBA, and they exhibited a shorter wetting time below 10 s. However, a slight color change was observed after the FBA process. These findings contribute to the production of protein-enriched food powders with improved properties.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/b0/pnfs-27-4-483.PMC9843709.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10593431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of Isoflavones and Their Potential Clinical Impacts on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients. 异黄酮及其对腹膜透析患者心血管和骨代谢指标的潜在临床影响综述。

Preventive Nutrition and Food Science Pub Date : 2022-12-31 DOI: 10.3746/pnf.2022.27.4.347

Zahra Yari

引用次数: 2