Preventive Nutrition and Food Science最新文献

Standardized Fingerroot (Boesenbergia pandurata) Extract Decelerates the Development of Sarcopenia in Aged Rats.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.47

Changhee Kim, Minseong Kang, Yeeun Kim, Jae-Kwan Hwang

{"title":"Standardized Fingerroot (Boesenbergia pandurata) Extract Decelerates the Development of Sarcopenia in Aged Rats.","authors":"Changhee Kim, Minseong Kang, Yeeun Kim, Jae-Kwan Hwang","doi":"10.3746/pnf.2025.30.1.47","DOIUrl":"10.3746/pnf.2025.30.1.47","url":null,"abstract":"Sarcopenia refers to the loss of muscle mass with age, significantly impacting the lives of the elderly. Fingerroot [Boesenbergia pandurata (Roxb.) Schltr.] exhibits antioxidant, anti-inflammatory, antibacterial, and anti-obesity activities. In this study, we demonstrated the inhibitory effect of fingerroot extract (B. pandurata extract, BPE) standardized with panduratin A on sarcopenia in aged rats. The results showed that BPE significantly increased the weights of the gastrocnemius and tibialis anterior muscle tissues and the cross-sectional area of the muscle fibers. In addition, BPE activated the phosphoinositide 3-kinase/Akt pathway, thereby activating the mammalian target of rapamycin pathway for protein formation and inhibiting proteolysis by decreasing forkhead box O3a-mediated muscle-specific ubiquitin ligases. BPE not only reduced tumor necrosis factor alpha and interleukin-6 levels but also stimulated the activities and mRNA expression of catalase and superoxide dismutase. The results suggest that BPE can be used as a functional food ingredient to inhibit or decelerate sarcopenia progression.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"47-55"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Soybean Extracts Prepared with Bionuruk^TM on Adipogenesis in 3T3-L1 Adipocytes.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.28

Hyeong-Woo Kim, Ha-Yull Chung

{"title":"Effects of Soybean Extracts Prepared with BionurukTM on Adipogenesis in 3T3-L1 Adipocytes.","authors":"Hyeong-Woo Kim, Ha-Yull Chung","doi":"10.3746/pnf.2025.30.1.28","DOIUrl":"10.3746/pnf.2025.30.1.28","url":null,"abstract":"Soybean isoflavone aglycones are more readily absorbed by humans than isoflavone glycosides and can inhibit adipogenesis. Various methods are used to convert isoflavone glycosides to their corresponding aglycones. However, few studies have used enzyme complexes to achieve this conversion. The present study examined the changes in the isoflavone profile of soybean extract prepared with BionurukTM, a fermentation starter (SE-B), and investigated its effects on lipid accumulation. SE-B was obtained by reacting soybean with BionurukTM at 37°C for 24 h. High-performance liquid chromatography was used to analyze the isoflavone profile of SE-B. The effects of SE-B on adipogenesis were assessed in 3T3-L1 adipocytes. Cytotoxicity and lipid accumulation were measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and Oil Red O assay, respectively. The mRNA and protein expression levels of adipogenesis-related transcription factors were measured by quantitative reverse transcription polymerase chain reaction and Western blot analysis. The isoflavone glycosides in SE-B were converted to their corresponding aglycones through the reaction with BionurukTM. Notably, the highest conversion rate was observed in SE-B10 (SE-B prepared with 10% BionurukTM), which exhibited the strongest inhibition of lipid accumulation (50.3% at 5.4 µg/mL). Furthermore, the mRNA and protein expression levels of peroxisome proliferator-activated receptor gamma, CCAAT/enhancer-binding protein-alpha, and adipocyte protein 2 were lower in cells treated with SE-B10 than in those with other treatments, and the effects were dose-dependent. In conclusion, isoflavone glycosides in soybeans were efficiently converted to their corresponding aglycones through the reaction with 10% BionurukTM, and SE-B10 inhibited lipid accumulation in 3T3-L1 adipocytes, suggesting its potential role in regulating adipogenesis in humans.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"28-36"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Packaging Variations on the Amino Acid Profile, Proximate Content, and Antinutritional Components of Tempeh from Jack Bean Sprouts.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.56

Friska Citra Agustia, Hery Winarsi, Aprilia Fitriani, Nurul Latifasari

{"title":"Impact of Packaging Variations on the Amino Acid Profile, Proximate Content, and Antinutritional Components of Tempeh from Jack Bean Sprouts.","authors":"Friska Citra Agustia, Hery Winarsi, Aprilia Fitriani, Nurul Latifasari","doi":"10.3746/pnf.2025.30.1.56","DOIUrl":"10.3746/pnf.2025.30.1.56","url":null,"abstract":"Jack bean sprouts are rich in plant-based proteins, which possess additional functional properties. However, no studies have reported using different packaging to ferment tempeh to increase the amino acids and nutritional properties of jack bean sprouts. The present study aimed to determine the effects of fermentation time and different packaging materials on the amino acid, proximate, and antinutrient concentrations of tempeh from jack bean sprouts. This study used experimental methods with two factors: fermentation time (36, 48, 60, and 72 h) and packaging material (plastic, banana leaf, and teak leaf). The results showed that the fermentation time contributed to significant changes (P<0.05), including an increase in the moisture, protein, and crude fiber contents of tempeh; a decrease in the fat and carbohydrate contents; and a decrease in antinutritional compounds (tannins, phytic acid, and hydrogen cyanide). The soluble protein content of tempeh was higher after 48 h of fermentation than after 36 h of fermentation, and the content remained consistent across all tempeh treatments until 72 h of fermentation. The amino acid concentration of tempeh fermented for 48 h was evaluated. Tempeh packaged in teak leaves exhibited the highest contents of essential and nonessential amino acids (34.27 and 58.97 g/100 g protein dry weight, respectively), followed by tempeh packaged in banana leaves and plastic. Regardless of packaging materials, tempeh fermented for 48 h contained the highest amounts of hydrophobic amino acids, including L-leucine, L-alanine, L-proline, L-phenylalanine, L-valine, and L-isoleucine.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"56-67"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Astragalus membranaceus Leaf Extract on Allergic Inflammation in Immune Cell Lines.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.68

Perleidulam Bunddulam, Mizuki Nakamura, Anuu Zorig, Yu Hinata, Mikako Takasugi, Chao-Hui Feng, Toshitsugu Sato, Hirofumi Arai

{"title":"Effects of Astragalus membranaceus Leaf Extract on Allergic Inflammation in Immune Cell Lines.","authors":"Perleidulam Bunddulam, Mizuki Nakamura, Anuu Zorig, Yu Hinata, Mikako Takasugi, Chao-Hui Feng, Toshitsugu Sato, Hirofumi Arai","doi":"10.3746/pnf.2025.30.1.68","DOIUrl":"10.3746/pnf.2025.30.1.68","url":null,"abstract":"Astragalus membranaceus is a perennial plant belonging to the Fabaceae family that is widely distributed across northern Asia. A. membranaceus roots have been used as a traditional medicinal herb because of their numerous health benefits. However, the physiological properties of A. membranaceus leaves remain unknown. During allergic reactions, chemical mediators are released from mast cells, which trigger immediate hypersensitivity and subsequent macrophage-mediated inflammation. In the present study, we investigated the inhibitory effects of A. membranaceus leaf extract (AMLE) on allergic and inflammatory responses in immune cell lines. The results showed that AMLE suppressed the release of histamine and leukotriene B4 from stimulated mast cells during allergic response by inhibiting the influx of calcium ions and downregulating the expression of 5-lipoxygenase. Moreover, AMLE suppressed the release of nitric oxide, prostaglandin E2, and cytokines from stimulated macrophages during inflammatory response. These effects were attributed to the suppression of mRNA and protein expressions of inducible nitric oxide synthase and microsomal prostaglandin E synthase-1 and the inhibition of the nuclear translocation of nuclear factor kappa-light-chain-enhancer of activated B cells. Compared with the A. membranaceus root extract, AMLE had more potent inhibitory effects. Quercetin and kaempferol, the predominant polyphenolic compounds present in AMLE, suppressed the release of chemical mediators during allergic and inflammatory responses in immune cells. These results suggest that A. membranaceus leaves have a therapeutic potential for alleviating allergic inflammation and that polyphenols are the primary bioactive constituents of A. membranaceus leaves.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"68-80"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced In Vitro Bioaccessibility and Anticancer Activity of Brazilian Propolis Extracted with L-Lactic Acid.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.81

Caglar Doguer, Fatma Duygu Ceylan, Esra Capanoglu, Nabil Adrar, Esra Bölük, Ali Timucin Atayoglu, Suzan Uzun, Ibrahim Palabiyik

{"title":"Enhanced In Vitro Bioaccessibility and Anticancer Activity of Brazilian Propolis Extracted with L-Lactic Acid.","authors":"Caglar Doguer, Fatma Duygu Ceylan, Esra Capanoglu, Nabil Adrar, Esra Bölük, Ali Timucin Atayoglu, Suzan Uzun, Ibrahim Palabiyik","doi":"10.3746/pnf.2025.30.1.81","DOIUrl":"10.3746/pnf.2025.30.1.81","url":null,"abstract":"This study aimed to investigate whether L-lactic acid (LA), as a better solvent than ethanol (EtOH), enhances the bioaccessibility of phenolic compounds in red and green Brazilian propolis and to evaluate their potential anticancer effects in vitro. In vitro gastrointestinal digestion was performed by sequentially subjecting propolis extracts to buccal, gastric, and intestinal digestion phases, and samples were collected at each stage for analysis. The total phenolic content (TPC) was determined using the Folin-Ciocalteu reagent with gallic acid as a standard. The total antioxidant capacity was evaluated using the cupric ion reducing antioxidant capacity and 2,2-diphenyl-1-picrylhydrazyl assays. The phenolic compounds of propolis samples were determined by high-performance liquid chromatography with diode-array detection analysis. The anticancer effects of propolis samples were evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The results showed that the TPC and antioxidant activity were markedly higher in the gastric and intestinal digestive products of LA propolis extracts than in those of ethanolic extracts. Treatment with red propolis LA extracts (RP-LA) resulted in a dose-dependent reduction in the viability of lung and colon carcinoma cells. Specifically, treatment with 1,750 ppm of RP-LA decreased the survival rate of carcinoma cells by 85% to 90%, whereas treatment with ethanolic propolis extracts at the same concentration did not exhibit any cytotoxic effect on cell viability. These findings suggest that LA is a more effective solvent than EtOH for extracting bioactive compounds from propolis, enhancing its antioxidant and anticarcinogenic potential.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"81-91"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Dietary and Lifestyle Management of Pre-Eclampsia and Postpartum Eclampsia.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.1

Muhammad Nadeem, Komal Javed, Hafiz Muhammad Rizwan Abid, Athar Hussain, Nauman Khalid

{"title":"A Review of Dietary and Lifestyle Management of Pre-Eclampsia and Postpartum Eclampsia.","authors":"Muhammad Nadeem, Komal Javed, Hafiz Muhammad Rizwan Abid, Athar Hussain, Nauman Khalid","doi":"10.3746/pnf.2025.30.1.1","DOIUrl":"10.3746/pnf.2025.30.1.1","url":null,"abstract":"Eclampsia is a prevailing hypertensive disorder that poses more significant risks to mothers and neonates globally. This review aimed to investigate eclampsia [preeclampsia and postpartum eclampsia (posteclampsia)] and the supportive role of dietary and lifestyle management. The review was compiled by searching various engines such as Google Scholar, Research Gate, BASE, PubMed Central, National Center for Biotechnology Information, and other related search engines. Eclampsia is believed to involve genetic and nongenetic factors, although the precise underlying mechanism remains unclear. Nevertheless, the traditional diagnosis of the disorder typically involves the coexistence of various factors such as an unhealthy lifestyle, diabetes mellitus, hypertension, low micronutrient levels, obesity, and proteinuria. Consuming at least 330 g fresh or 4 g dried fruits daily minimizes preeclampsia. Diets high in sugar, fat, and salt are associated with higher vulnerability to the disease. Calcium supplementation is beneficial for women as it helps to reduce the occurrence of preeclampsia. Evidence for vitamin D supplementation is inconclusive and requires further research. Selenium supplementation has shown a negative correlation with the chance of preeclampsia. Dietary patterns with higher intakes of a plant-based diet, including micronutrients, and a healthy lifestyle significantly reduce the risk of preeclampsia and posteclampsia. Furthermore, clinical trials could explore the potential benefits of dietary supplements in preventing or treating eclampsia. There is a need for further exploration into the benefits of personalized medical nutrition therapy for preeclampsia and posteclampsia. Lastly, modern prognostic tools can diagnose disorders promptly and help with effective medicinal and nutritional management.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"1-20"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Instant Pumpkin Soup on the Antioxidant Capacity and Oxidative Stress of the Elderly.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.21

Wawan Saepul Irwan, Budi Setiawan, Ahmad Sulaeman, Hardinsyah, Tjahja Muhandri

{"title":"Effects of Instant Pumpkin Soup on the Antioxidant Capacity and Oxidative Stress of the Elderly.","authors":"Wawan Saepul Irwan, Budi Setiawan, Ahmad Sulaeman, Hardinsyah, Tjahja Muhandri","doi":"10.3746/pnf.2025.30.1.21","DOIUrl":"10.3746/pnf.2025.30.1.21","url":null,"abstract":"Oxidative stress is an important contributor to degenerative diseases in the elderly. Pumpkin is known for its potent antioxidant properties. The present study evaluated the effects of two types of instant pumpkin soups on the antioxidant capacity and oxidative stress in the elderly. This study used a quasi-experimental design to compare two types of instant pumpkin soups: instant pumpkin soup supplemented with chicken breast (IPB) and instant pumpkin soup prepared with the original recipe (IPO). Plasma antioxidants [superoxide dismutase (SOD), glutathione peroxidase, and catalase] and oxidative stress markers [malondialdehyde (MDA), oxidized low-density lipoprotein (ox-LDL), 8-isoprostane, tumor necrosis factor-α (TNF-α), and 8-hydroxy-2'-deoxyguanosine (8-OHdG)] were analyzed using enzyme-linked immunosorbent assay. The results showed that IPB had higher protein (13.40% vs. 2.20%), fiber (13.9% vs. 9.21%), β-carotene (6.28 mg/100 g vs. 3.38 mg/100 g), vitamin A (96.63 µg/100 g vs. 81.82 µg/100 g), and ash contents (5.68% vs. 3.00%) than IPO. Both soups demonstrated antioxidant activity, with IPB showing greater effects than IPO. IPB significantly increased the plasma SOD (432.63±396.03 pg/mL; P=0.011), but not IPO (127.30±364.69 pg/mL; P=0.326). Both soups reduced plasma ox-LDL, TNF-α, and 8-OHdG levels. Compared with IPO, IPB significantly decreased plasma MDA levels (P<0.05). Reductions in ox-LDL (-555.03±155.86 vs. -83.09±66.45 pg/mL; P<0.001) and TNF-α (-58.24±22.85 vs. -30.59±18.08 ng/mL; P=0.012) were significantly greater in the IPB group than in the IPO group. These findings suggest that IPB may serve as a functional food for reducing oxidative damage in the elderly.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"21-27"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of Functional Compounds and Antioxidant Activity in Houttuynia cordata Thunb. Leaf Extracts Through Lactiplantibacillus plantarum Fermentation.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.92

Cheng-Chieh Chou, Simon Anthony Kayombo, Chao-Hsiang Chen, Chih-Min Yang

{"title":"Improvement of Functional Compounds and Antioxidant Activity in Houttuynia cordata Thunb. Leaf Extracts Through Lactiplantibacillus plantarum Fermentation.","authors":"Cheng-Chieh Chou, Simon Anthony Kayombo, Chao-Hsiang Chen, Chih-Min Yang","doi":"10.3746/pnf.2025.30.1.92","DOIUrl":"10.3746/pnf.2025.30.1.92","url":null,"abstract":"This study aimed to compare the functional compounds and antioxidant activity of Houttuynia cordata Thunb. (HC) leaves and stems harvested in summer and winter and to select the optimal sample to determine its growth-promoting effects on Lactiplantibacillus plantarum. Dried HC leaves and stems were extracted using boiling water, and colorimetric methods were used to measure their total polyphenol and flavonoid contents and antioxidant capacity. High-performance liquid chromatography was used to determine the content of active compounds, including quercitrin, hyperoside, and quercetin. The results showed that the raw materials of HC leaves harvested in summer had significantly higher quercitrin and hyperoside contents compared with those of HC stems harvested in winter. Boiling water extracts of HC (BWEHC) leaves harvested in summer also exhibited higher total polyphenol and flavonoid contents and antioxidant activity than stems harvested in winter. During fermentation, BWEHC leaves were fermented with L. plantarum at solid-solvent ratios of 0.3%－1.5% (w/v) for 24－72 h. The optimal fermentation condition was a solid-liquid ratio of 0.9% (w/v) with a fermentation time of 48 h as this condition resulted in the highest bacterial counts. After fermentation, the quercetin content, total polyphenol and flavonoid content, and antioxidant activity significantly improved, whereas the quercitrin and hyperoside contents decreased compared with those in nonfermented samples. The L. plantarum count was considerably higher in BWEHC leaves than in the control group. In conclusion, BWEHC leaves could serve as a potential prebiotic for L. plantarum and may offer benefits as a functional food.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"92-100"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of a Novel Fortified Dairy Product on the Psychological Status and Sleep Quality of Patients with Polycystic Ovary Syndrome: A Double-Blind Randomized Controlled Trial.

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2025-02-28 DOI: 10.3746/pnf.2025.30.1.37

Moein Askarpour, Najmeh Hejazi, Bahia Namavar Jahromi, Mohammad Hadi Eskandari, Mandana Famouri, Alireza Bedeltavana

{"title":"Effects of a Novel Fortified Dairy Product on the Psychological Status and Sleep Quality of Patients with Polycystic Ovary Syndrome: A Double-Blind Randomized Controlled Trial.","authors":"Moein Askarpour, Najmeh Hejazi, Bahia Namavar Jahromi, Mohammad Hadi Eskandari, Mandana Famouri, Alireza Bedeltavana","doi":"10.3746/pnf.2025.30.1.37","DOIUrl":"10.3746/pnf.2025.30.1.37","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a neuroendocrine disorder that commonly causes anovulation and infertility worldwide. Aside from infertility, patients with PCOS suffer from sleep disturbances and mental health issues. Recent studies have shown that functional foods may have a beneficial impact on psychological disorders and sleep quality. Therefore, the present study aimed to investigate the effects of daily intake of a fortified yogurt on the psychological and sleep profiles of women with PCOS. In this 8-week randomized double-blind controlled trial, after a 2-week run-in period, participants in the intervention group (n=45) received yogurt fortified with 106 colony-forming units/g of probiotics (Bifidobacterium animalis Bb-12 and Lactobacillus acidophilus La-5) along with 50 IU of vitamin E and 1,000 IU of vitamin D, and those in the placebo group (n=45) received low-fat yogurt. The psychological status and sleep quality of patients were measured using the Depression, Anxiety, and Stress Scale-21 Items and Pittsburgh Sleep Quality Index before and after the study, respectively. The registration number of this study was IRCT20231210060323N1. The results showed that the intervention group exhibited a significant improvement in depression status compared with the placebo group (P=0.01). However, no statistically beneficial impact was observed on sleep quality in patients with PCOS (P=0.44). This trial indicated that consuming yogurt with probiotics, vitamin E, and vitamin D may alleviate depression in patients with PCOS and that nutritional interventions could be advantageous, particularly for individuals who prefer not to take antidepressant medications. However, further research is needed to confirm the results.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"30 1","pages":"37-46"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Water Extract of Djulis Husk Exerts Protective Effect Against Metabolic Syndrome. 枣壳水提物对代谢综合征的保护作用。

IF 1.6

Preventive Nutrition and Food Science Pub Date : 2024-12-31 DOI: 10.3746/pnf.2024.29.4.466

Liang-Yi Wu, Wei-Lun Hung, Ling-Yun Cheng, Zheng-Yuan Su, Bo-Yang Hsu

{"title":"Water Extract of Djulis Husk Exerts Protective Effect Against Metabolic Syndrome.","authors":"Liang-Yi Wu, Wei-Lun Hung, Ling-Yun Cheng, Zheng-Yuan Su, Bo-Yang Hsu","doi":"10.3746/pnf.2024.29.4.466","DOIUrl":"https://doi.org/10.3746/pnf.2024.29.4.466","url":null,"abstract":"Djulis (Chenopodium formosanum Koidz.) possesses various biological activities, including anti-oxidant, anti-hyperglycemic, anti-aging and hepatoprotective properties. Although djulis husk is typically considered agricultural waste, there is value in exploring ways to utilize it effectively. This study aimed to investigate the protective effects of the water extract of djulis husk (WDH) in rats with high-fructose-induced metabolic syndrome. The results showed that WDH significantly ameliorated the metabolic syndrome induced by a high-fructose diet in rats. Supplementation with low-dose WDH (0.5% of diet, w/w) significantly improved metabolic syndrome, including high blood pressure, hypertriglyceridemia, and insulin resistance. The protective effects of WDH against metabolic syndrome may be associated with increased expression of the genes encoding insulin receptor substrates-1 (IRS-1) and glucose transporter 4 (GLUT-4) in the epididymal fat. Thus, WDH is likely a functional food ingredient for the prevention of metabolic syndrome.","PeriodicalId":20424,"journal":{"name":"Preventive Nutrition and Food Science","volume":"29 4","pages":"466-473"},"PeriodicalIF":1.6,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0